DRUG MODE OF INDICATION DOSAGE DRUG ADVERSE EFFECT

ACTION INTERACTION
Levodopa Transported into Parkinson 100mg Use with Carbidopa GIT upset,
the CNS and diseases greatly diminishes arrhythmias,
converted to required dosage. dyskinesia, on-off and
dopamine, also in Use with COMT or wearing off
periphery MAO-B inhibitors phenomena.
of prolong duration Behavioral
effect, disturbance.
Thioridazine Blockade of D2 Bipolar 15mg α-receptor blockade akathisia
receptor >>5HT disorder M receptor
receptor blockade
Fluphenazine Blockade of D2 Preoperative 2.5mg α-receptor blockade Dyskinesia
receptor >>5HT sedation M receptor
receptor blockade
Haloperidol Blockade of D2 Tourette 0.5mg α-receptor blockade Extrapyramidal
receptor >>5HT syndrome M receptor dysfunction
receptor blockade
Olanzapine Blockade of 5-HT Bipolar 2.5mg M receptor Hypercholesterolemia
receptors> disorder blockade
blockade of D2
receptors
Risperidone Blockade of 5-HT Bipolar 2mg H receptor Hyperprolactinemia
receptors> disorder blockade
blockade of D2
receptors
Clozapine Blockade of 5-HT Schizophrenia 12.5mg α-receptor blockade Weight gain
receptors> H receptor
blockade of D2 blockade
receptors
Aripiprazole Blockade of 5-HT Major 2mg H receptor Agitation
receptors> depression blockade
blockade of D2
receptors
Quetiapine Blockade of 5-HT Schizophrenia 25mg H receptor constipation
receptors> blockade
blockade of D2
receptors
Ziprasidone Blockade of 5-HT Schizophrenia 20mg α-receptor blockade QT prolongation
receptors> H receptor
blockade of D2 blockade
receptors