ICP-MS Application-Training

Part 2 - PlasmaQuant® MS

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Features of the PlasmaQuant® MS

▪ Eco Plasma

▪ iCRC Interference
Management

▪ ReflexION Ion Mirror

▪ HD Quadrupole

▪ ADD10 Detector
Strengths of the PlasmaQuant MS

Innovative
and Patented
Technology

Lowest
Highest
Operating
Sensitivity
Cost

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 Innovative Design Concepts

▪ Small and configurable footprint

➢Fits into any lab environment

▪ Dual entry into the torch compartment

➢Flexibility for various accessories

▪ Open-book design

➢Easy access to interface cones

▪ New RF Generator Design

➢Most stable plasma, lowest gas consumption

▪ New vacuum system

➢Better vacuum, outstanding durability

▪ Nitrox option to add O2/N2 to the plasma

➢Performance optimization

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Simplified Maintenance Process

▪ Simply pull down the handle and

open the plasma compartment
door to get access to the ICP-
MS interface
▪ All sample introduction
components remain installed and
positioned
▪ Change cones and get access to
the 1st and 2nd extraction lens
without breaking the vacuum

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 Plasma generation

▪ New design, free running solid-state RF generator

▪ Variable power from 300 to 1600W

▪ 6-9 L/min plasma (cooling) gas flow

▪ Reduce argon gas consumption by 50%

▪ Standard conventional one-piece torch

▪ Robust for high salt matrices and organic solvents using a conventional torch

▪ Exceptional ‘cool plasma’ performance

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Argon Gas Cost Savings

Cylinders
Replacement Cost $US120
Total Gas Flow of a 18L/min
typical ICP-MS
Time to Replacement 1 day
(8hr working day)

Annual cost $US30000

(5 days/week)

Annual cost saving with $US15000

PQMS (9 L/min)

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 Plasma Robustness

▪ Higher plasma efficiency

▪ Handles same high sample matrices with less RF Power

▪ Seawater, geological, organic solvents, solid particles

 ReflexION Ion Optics

3D Reflecting Ion Mirror

▪ Original 90° ion optics design

▪ ‘The Mirror’ is a parabolic electrostatic field

▪ Tight focusing of ions without aberrations

▪ Superior ion transport efficiency across all masses

▪ Photons and neutral particles pass through

▪ Full 3D control of the focus point = Tunable sensitivity

▪ Maintenance free
ReflexION in the PlasmaQuant® MS

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Reflecting Ion Mirror – 3D Control
ReflexION in the PlasmaQuant® MS

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 Integrated Collision Reaction Cell

▪ Inject gas into „high pressure“ / low volume collision-reaction zone

➢High pressure = more collisions

▪ Fast, efficient removal of spectroscopic interferences

➢Interference removal before entering ion optic / high vac.

➢Unwanted by-products can‘t enter MS
▪ New gasbox design and improved vacuum

➢switch between gas and non-gas modes in seconds

▪ Reduced gas quality requirement

➢Common CCT: 99.999% + filter

➢PQ MS: 99.996%
➢Compatible with Hydrogen generator for greater safety
▪ No additional consumables / maintenance of Collision Cell
 Integrated Collision Reaction Cell (iCRC)

Common Interferences in ICP-MS

▪ Ar based interferences

▪ H2 is best

▪ Ca, Fe, Se Element Isotope Interfering ion

Calcium 40Ca 40Ar+

▪ But: Competitors offer H2
Vanadium 51V 16O35Cl+
only optional
Chromium 52Cr 40Ar12C+
▪ Sample matrix based interferences
Iron 56Fe 40Ar16O+

▪ He is best Arsenic 75As 40Ar35Cl+

▪ V, Cr, As Selenium 78Se 40Ar38Ar+

80Se 40Ar40Ar+
▪ Competitors push
All-Helium mode
Collision-Reaction Cells

Analyte
75As

Interference
40Ar35Cl
40Ca35Cl

He gas

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 Mass Analyzer – 3MHz Quadrupole

Curved entrance rods

▪ Double off axis quadrupole
▪ Removes excited neutrals before reaching
quadrupole
▪ Lowest possible backgrounds (<1cps)
▪ Lower detection limits

High Definition Quadrupole

▪ 3MHz for superior mass separation
▪ U 238 low mass, abundance sensitivity
▪ ~ 2.4 x 10-8
▪ 50µs Dwell Time
 Abundance sensitivity

m/z 237 238

cps 3.8 1,6 x 108
Abundance Sensitivity 2,4 x 10-8
All Digital Detector

▪ Discrete Dynode Electron Multiplier

▪ Unique DDEM, exclusive to Analytik Jena

▪ 10 orders of linear dynamic range

▪ In all-digital ‘pulse-counting’ mode

▪ Attenuation of the electron pulse

▪ No separate analog electronics

▪ No regular cross-calibrations

Cross
calibration

Intensity
Analog

Signal
Pulse Counting

ppt ppb ppm

All Digital Detector

▪ 10 orders of linear dynamic range

▪ 2 stage electronic “dilution” of the signal

▪ Auto or manual attenuation setting

▪ Increases detector lifetime: > 3 years

(Competitors: > 0.5 years)
A Synergy of Technology

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Two New Models

PlasmaQuant MS Elite
▪ Configured for maximum sensitivity
▪ Minimum 1.5 Mc/s/ppb on In115
▪ Challenges magnetic sector-field ICP-MS
▪ Not everyone needs high sensitivity
▪ But no one offers such high sensitivity on quad ICP-MS

Perfect for Research Applications

▪ Laser ablation sample introduction
▪ Single-particle analysis
▪ Isotope ratio measurements
▪ HPLC-ICP-MS
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 Two New Models

PlasmaQuant MS
▪ Configured for routine applications
▪ Minimum 0.5 Mc/s/ppb on In115
▪ Exceeds other quadrupole ICP-MS
▪ Cone interface and sample introduction optimized for
higher throughput, routine sample matrices

▪ Drinking water, waste water, seawater, etc

▪ Soils, sediments, sludges
▪ Food safety, pharmaceuticals
▪ Chemicals and petrochemicals
▪ Agriculture, etc…. 23
Thank you for your attention!