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Fluid Solid Interaction Benchmarking of An External Coupling of ANSYS With CFX For Cardiovascular Applications
Fluid Solid Interaction Benchmarking of An External Coupling of ANSYS With CFX For Cardiovascular Applications
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D. R. Hose{*, P. V. Lawford{, A. J. Narracott{, recognizing the interaction of the ¯uid ¯ow with the
J. M. T. Penrose{ and I. P. Jones{ deformation of the arterial walls, been attempted.
{Medical Physics, University of Shef®eld, UK McQueen and Peskin [1] have presented one of the
{AEA Technology, Harwell, UK most advanced cardiac applications of ¯uid ± solid
interaction (FSI), using a custom-developed immersed
Fluid ± solid interaction is a primary feature of cardiovascular
boundary method. FSI is critical for the analysis of
¯ows. There is increasing interest in the numerical solution of
systems like heart valves, for which opening and closure
these systems as the extensive computational resource required for
characteristics can only be computed in a coupled
such studies becomes available. One form of coupling is an
manner. Even for arterial geometries the wall motion
external weak coupling of separate solid and ¯uid mechanics
can be important, particularly with respect to the
codes. Information about the stress tensor and displacement computation of parameters such as wall shear stress.
vector at the wetted boundary is passed between the codes, and an
iterative scheme is employed to move towards convergence of these
There are several approaches to the coupling process.
parameters at each time step. This approach has the attraction
Strong coupling features integrated solution of the
that separate codes with the most extensive functionality for each
¯uid and the structural variables, and is likely to be
of the separate phases can be selected, which might be important
most stable for general situations. There are various
in the context of the complex rheology and contact mechanics
forms of weak coupling, featuring iteration between
that often feature in cardiovascular systems. Penrose and Staples
solids and ¯uid solution software with transfer of data
describe a weak coupling of CFX for computational ¯uid
on the wetted boundary (e.g. [2]). A primary argument
mechanics to ANSYS for solid mechanics, based on a simple
for weak coupling is that it might offer the facility to
Jacobi iteration scheme. It is important to validate the coupled `bolt together' leading commercial codes with the most
numerical solutions. An extensive analytical study of ¯ow in
complete functionality for the separate solid and ¯uid
elastic-walled tubes was carried out by Womersley in the late
mechanics phases. The advanced features required to
1950s. This paper describes the performance of the coupling describe many of the phenomena associated with
software for the straight elastic-walled tube, and compares the
cardiovascular systems are unlikely to be resident within
results with Womersley's analytical solutions. It also presents
a single suite of programs. On the structures' side the
preliminary results demonstrating the application of the coupled
tissues are primarily nonlinear and anisotropic, and
software in the context of a stented vessel.
appropriate functions for the representation of their
stress ± strain characteristics are featured only in ad-
vanced structural solvers. Contact is also a common
Introduction feature which needs to be handled by the structural
analysis software. On the ¯uid's side, the rheology of
Over the last two decades there has been an enormous blood is complex: it is certainly non-Newtonian at some
increase in the application of numerical methods to the shear rates, and indeed two-phase plasma/erythrocyte
solution of complex three-dimensional cardiovascular representations might be most appropriate. There is
systems. The facility to calculate local ¯uid dynamic also the likelihood of turbulence in some cardiovascular
parameters on meaningful length scales has great systems, including distal to aortic heart valve prostheses
implication for the understanding of haemodynamic and at some arterial stenoses. For real application to
processes and for the design of prostheses. As an bene®t our understanding of haemodynamic processes,
example of the former, ¯uid shear stresses are including haemostasis and thrombosis, multiple species
implicated in the processes of haemolysis, thrombosis, and chemical reaction representation are important. In
thromboembolism and atherosclerosis, and of the terms of post-processing, transient particle tracking is
latter, the pressure drop is an important measure of an important feature for the assessment of haemolysis
heart valve performance. Fully transient numerical and its contribution to thrombotic processes.
studies of blood ¯ow in systems such as bifurcations,
anastomoses and heart valve applications have been Generic interfaces for the external coupling of struc-
performed for close to a decade. It has been normal to tural and ¯uid solvers have been produced, including
assume that the walls of the ¯uid domain are ®xed. one that featured an analysis of a mechanical heart
Only relatively recently have fully-coupled analyses, valve as a target application [3]. Many investigators have
coupled speci®c codes for a particular application,
*Author for correspondence. e-mail: d.r.hose@shef®eld.ac.uk including for arterial segments [4] and bifurcations [5].
24
D. R. Hose et al. Fluid ± solid interaction
Figure 1. Velocity as a function of radius, from centreline to wall, at eleven different times in a sinusoidal cycle for three values of
the Womersley parameter: (a) a small; (b) a=2.5; (c) a large.
A* exp [io (t ± z/c)], where c is the wavespeed. It should assumption of ¯uid homogeneity and Newtonian
be noted that the wavespeed, c, is complex, and so the viscosity for blood to apply.
phase of the pressure wave is not, in general, 908 from
that of the pressure gradient. The wavespeed, c0, in a The modi®ed Moens ± Korteweg wavespeed is
longitudinally tethered thin-walled elastic tube of 5.6 m s71. For a pulse wave of frequency 1 Hz this
thickness h, Young's modulus E and Poisson's ratio n, implies a wavelength of 5.6 m. The characteristic length
carrying a ¯uid of density r and zero viscosity is of this vessel, associated with the assumption of
1=2 negligible bending stiffness, is 0.00056 m, and so it is
Eh assumed that the bending stiffness of the vessel can be
c0 :
2Rr
1 ÿ n2 neglected. Analyses were performed with domain
lengths of 0.0005 m and of 0.004 m, and over these
This is the Moens ± Korteweg expression for wavespeed length scales it can be assumed that the pressure
in an elastic tube, modi®ed by the Poisson's ratio terms gradient, qp/qz, is constant.
associated with the longitudinal tethering. The viscosity
of the ¯uid acts to reduce the wavespeed, to change the The Cartesian co-ordinates were aligned such that the z
relative phases of pressure, gradient and ¯ow, and to axis corresponded to the tube axis, and a model of one
damp the pressure wave as it travels down the tube. The quarter of the system, represented by the positive xy
reduction in wavespeed is less than 2.5% for Womersley quadrant, was constructed.
parameters greater than three [13]. A basic assumption
in its derivation is that each longitudinal element of the Boundary conditions. The wetted boundary between the
tube acts structurally as an independent ring under an solid and ¯uid phases was de®ned as an interface
applied internal pressure. The bending stiffness of the between the solid and ¯uid analysis codes. Both ¯uid
tube is assumed to be negligible and so there are no planar boundaries normal to the tube axis were de®ned
internal transverse shear stresses in the wall of the tube. `openings' in CFX, permitting ¯ow either into or out of
This condition will be satis®ed if the wavelength of the the domain. Conventionally these boundaries might be
pressure pulse is long compared with the characteristic referred to as the inlet and outlet but these terms are
length of the tube. The characteristic length, or the less relevant in the context of pulsatile ¯ow with a mean
axial distance from an applied ring load at which the of zero. The ¯uid planes yz and zx were de®ned as
deformation in a cylinder will pass through zero, is symmetry boundaries, with no ¯ow perpendicular to
given by x=p/2b, where b=[3(1 ± n2)/R2h2]1/4 [14]. them.
25
D. R. Hose et al. Fluid ± solid interaction
1305 Pa (%10 mm Hg). The phase was chosen such alone, i.e. entirely within CFX, with standard no-slip
that the pressure was zero at time zero. wall boundary conditions. The sensitivity of the solution
to mesh density, element type (hexahedral or tetra-
The Womersley parameter, a, for this system is 2.51. hedral), and order of integration scheme was investi-
Womersley's solutions indicate that the pressure gra- gated. In all cases the variation associated with change
dient leads the pressure by 67.58 and the ¯ow by 458 of these parameters was small. The meshes used are
and thus ¯ow leads pressure by 22.58. The amplitude of illustrated in ®gure 3 for the two lengths of ¯uid
the ¯ow wave is 2.1461076 m3 s71. Normalized plots domain studied.
of pressure, pressure gradient and ¯ow against time for
this system are presented in ®gure 2, illustrating the The parameter of most importance was the conver-
relative phase of the three quantities. gence criterion at each time step. It was found that
analyses with a convergence criterion of 161074, the
Static pressure was speci®ed as a function of time on default in CFX, consistently underpredicted the magni-
both openings of the ¯uid domain with an appropriate tude of the velocities at all time steps. Results with
phase lag between them, as computed from Womer- convergence criteria of 161075 and 161076 pro-
sley's solutions. The analysis was started from time zero duced excellent agreement between computed and
with a zero value of the pressure at the inlet and an analytical velocity pro®les. This is illustrated in ®gure 4,
appropriate phase-lagged pressure at the outlet. The in which the velocity on the tube axis (centreline) is
velocity pro®le at time zero was computed and applied plotted against time for the numerical studies with each
as an initial condition node by node to all nodes of the of the speci®ed convergence criteria and for the
¯uid domain. The pro®le applied was that computed analytical solution.
for z=0, on the assumption that the ¯ow variation along
the short domain is negligible. A typical result at a time step is illustrated in ®gure 5.
The velocity pro®le at each opening is presented as a
Time duration. The analysis was run for one half of a series of vectors and the pressure as a colour fringe plot.
sine-wave pressure cycle, i.e. 0.5 s at 1 Hz. After this The velocity pro®le is semi-parabolic and it can be seen
point the pressure would become negative. The analysis that the pressure is effectively a function of axial
has not been extended to the negative pressure phase, position only, i.e. independent of radius. The pressure
although some preliminary results have been obtained gradient is constant along the domain.
in this region. The critical pressure, pcr, in a long-
itudinally-tethered elastic tube at which elastic instabil- In order to investigate sensitivity to initial conditions an
ity is anticipated is Eh3/4R3 (1 ± n2), or 39.2 Pa for the analysis was carried out with zero initial velocity rather
current system. The ®rst buckling mode has two lobes than the prescribed Womersley velocity pro®le. The
(an ovalization), and is symmetrical about xz and yz time taken for a Poiseuille parabolic ¯ow pro®le to
planes. This mode can be captured by the quarter- develop in a tube full of ¯uid initially at rest is of the
model boundary conditions. order of 0.75R2r/m, or 0.75 s, and so it might be
anticipated that the ¯ow pro®le could develop towards
a consistent harmonic response over perhaps one cycle.
Results This was con®rmed in the numerical study. The ¯ow
pro®le at the end of a second sinusoidal pressure wave
was less than 1% changed from that at the end of the
Rigid tube
®rst wave.
As a preliminary to the execution of the coupled
solution, analyses were conducted in the ¯uid domain
Elastic tube
The analysis was performed using the BloodSim
coupling of ANSYS and CFX for a positive half sine
pressure wave using the dimensions and initial and
boundary conditions prescribed earlier. A convergence
criterion was adopted for the ¯uids analysis, based on
the results of the rigid tube study. Convergence of the
coupling cycle at a time step was assumed when the root
mean square of the pressure vectors on the wetted
boundary, calculated from two successive iterations of
the ¯uids solve, were consistent to within 1%. The
pressure relaxation parameter, describing the propor-
tion of newly computed to previously converged
solution adopted at each time step for the application
of pressure from ¯uid to solid phase, was 0.2. The
number of coupling iterations required for conver-
gence depends on the time step. A minimum of 20 and
maximum of 30 coupling iterations were speci®ed for a
Figure 2. Temporal variation of pressure, pressure gradient time step of 0.002 s. In practice after 20 coupling
and ¯ow for a=2.51, illustrating relative phase. iterations the chosen pressure and displacement con-
26
D. R. Hose et al. Fluid ± solid interaction
Figure 3. Meshes used for rigid tube analysis: (a) 0.5 mm length, hexahedral mesh; (b) 0.5 mm length, tetrahedral mesh; (c) 4 mm
length, hexahedral mesh.
27
D. R. Hose et al. Fluid ± solid interaction
Longer tube
These analyses of short longitudinal domains serve to
provide con®dence in the solution methodology and
coupling software. However it is very dif®cult to
monitor accurately the spatial transmission of the
pressure pulse in such a system. An analysis was
performed of a tube of the speci®ed geometry, but of
length 0.08 m. For this analysis a frequency of
18.9 rad s71 was speci®ed for the pressure wave,
corresponding approximately to the zero-to-peak ramp
of the pressure waveform in the carotid artery at the
onset of a systolic pulse. The Moens ± Korteweg
wavespeed is 5.6 m s71 and the wavelength is 1.86 m,
still over twenty times longer than the solution domain.
A viscosity representative of water, 0.001 Pa s, was
speci®ed for the ¯uid phase. For this system the
Figure 6. Centreline velocity versus time: effect of time step Womersley parameter is 8.7. The inlet boundary had
and comparison with analytical solution. a prescribed pressure varying linearly with time at a rate
of 22 mm Hg in 0.083 s, or 35 250 Pa s71 (based on the
carotid ¯ow waveform). The outlet pressure was
prescribed to be zero. A coupling loop pressure
relaxation parameter of 0.02 was found to produce
acceptable convergence characteristics.
28
D. R. Hose et al. Fluid ± solid interaction
Figure 8. Form of buckling of elastic tube wall and associated deformed ¯uid mech under negative ¯uid pressure; coupled analysis.
Figure 9. Dilation of tube under ramped inlet pressure, 1 ms time increments, with snapshot of scaled dilated geometry at
3 milliseconds.
29
D. R. Hose et al. Fluid ± solid interaction
30
D. R. Hose et al. Fluid ± solid interaction
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