ere ‘AS earl bo is brout o your ofc ih fal edema ely cobred ube. His realist te for anid sn rfecten on fsfoce ee weeks go Uris ody poste fo aetah.The Barter respenate ethic patents reset have wih of ean charac? XE A Catalase poste 10%] 1 © 8 Bacar POM] © Coapuse-psine 119) 1 Renter FI using racton post 6 Eoplanatin: ser s86t47 Themestitely dogoss here is acute post-sreptococcal emeunepnis (PSG) an mune {omplemeaute disease occurs lew feton by segeaed peptegeic sans ‘Srenonccevs pyogenes i Astelec:tts GAS) Spies Nal Ute PENI Inercepedet) sera and unetil sak nde Gucto hema Casseat, te GAS reecionthat, recedes ASPON il be ete hangs [sep toa or wciareos recon sucha an bse, fruncicempetgs GASIs wcsalose-reate, beater, ram pose coeeus senstvet bactresn (hole a) Soptyococe ae catatse-estie, Gam postvecoc Saves can cause mute peso fete, cheng culaneous recone, sep ar, etearyehs an woud feeb {hole ¢) S aureus is oat cxaplase postive, Gram pose caecs, (hole) Norham oraniams af refered to as gar herlfc. Some woup Deepacoc ich Sethe ontrocoec se gana nama} Thos organs may cause subacute bacterial enc. (hole) nen Sropincoecus meumanse i exosedn abate aan ts aps agen, sting OF baceral capsules enderturder he mcrosepe This skal dees 3 postive GuohngYeacionere Cangas pate) Nene 5 E ueting reactor poste Themestitaly agnosis hr acute post-sraptococcl gemendonephis (APSO) en inne Complecmoacteedosace ha occu olwngrfacon by rogenaednephicgon aan ‘Shentccrevs pyogenes eee Astepeca:cus, GAS) Syrplms peal Aude peta inendependert saena snd ube bt din cr due a hamaturi Cassese GAS wfecon that Precedeo ASPCN wi be eter haryigto step trou) or a cuareos techn suchas an abscess, uncle cepetga. GAS iow eulace nga, bea hema, tam pose occu sense tectraen, (Chole A) Staphyncoce ae catalase peste, ram postive coc S.aweus cn cause mute peso ‘fete, dg euaneous itecons, cop a, ealearylis and Naud econ (hee €) 8 oureusis teat caspase poste, Gram posive cece. (Chee D) Non arte esaniams af refed ao ganmaharbic. Smo group D sepacocl uch sete enlerococe re para haji. Teas gear ay cave subacle acer endear. (hole) vnen streancoecus pumas nposedo abate agant ts capsuaangens owen ‘Ye acer capsules enderturde he mcroscepe This over dees agstve Guelng faction veto! objective: Group aatepococeus is catalase nyse beta hema, Cram postive coccus senate ta bactacn, tmune compl medd dacaoes he teuabc ee and ace post aretocecal gemerucnephia a ecu tlowing GAS reco Time sper 22 seconds 17 answer corey ast pa (77200) Cann USMLEWLD ILE Sean 2011130295Tem: 2 of 46 |ADtiyear ld Couns mal ee wo eke 258th anos for ray symp now ret a fhe complning ef ark pan ae ify waleng Phy examina vet a wale et ght bce andes eyereanezs Wacol the lloning the moa ly donee cpt? 1 yperseratny vascuts [>] 18 Oisserrates genococcaliecton 23%] 16 C.Reactve tts 1) 1 feljosng por] hcunatit artis (0) Fra are) Classical, reatve ais "Rater sytem) ocusin alsin her meres andthe. Tis condion 'Seneactorae byte ado canunetos, us acres ars oe gpendicus keen Bt tected nace poste for HUA ST (hoee 4) ypersenstnty some sa sere eaten (yey tars aeplegte agers or Ssframigeaocs) mat esut a ever, hepais stags, ymphadercpay er esto ‘jstinchen apprneaiy toto Si wees ere dg ses use (hole 8) Dssemined goracoca fecten resents ther as purdet ars peal ofthe kee, ‘hrm ora) or asthe rad erosnnits, Genmatsara rampant pobarhamas. ve smpans {hole D) Arkbsing sponds cron ranma dase of me acu ant przarear Srucures rite a secon. Ts ore scoregve atts presents wih poses spa sessTem: 2 of 46 seri: 380147 Classica, eactve atts "Retr sytem) acum les ne heres andes. Tis cnaton SSenaracrae byte Wad of canunctNts cvs ard stoneoive aso De pends Steen (ina, ars, an tet pai) an assocatan femabered whe tenon cat seo ca ee, {anvcip tee" Gematnay wien or dared cased by Chanda, Canova Saat ‘Stoo ar Yersna precedes he coset al eumaie symplaraby lots sheets W aden, mate than Bf ace eas se poste HLA SZ (hole A) Hpersersvty some sa severe reaction ype aroma ate agers or Safoarce ats) ta rests mash eve epaots ava mpnederepay cremate sun apron to se wees fe the gs Wk sed (chee B) Dscominstd goracocea efcton pas ctr as pret ais ype te kee, to i) a the adaltanasjonns, dma, andar pul payrbvagae. Ey aHoMs (CholeeD) Anyang opondiis oa chai fama dcase of mute aul and prea er Sucues rte au slaleton, Tiare eunepave ati presents wih pomeesne cp stiess bed bck pan (holes €)Rreunstod anti inaeha, rtanmtary doses of mute sects ype) Scud wt metcaroptalagea, oe pouna rerphaangeal arts} omng then Comm, (hole fa anes i symmensaarclardssace secs wth pen, eps vs Fepatts Cs, nets vis sl apharrs recon veto! objective Feachve aris (eer syndume is chatacterced by the ado conn, retis, ad seronegative ‘sis fe sopendcl steleton Timespere 52 secorts ots answered coecty astupete 107014 apni USMLEWORLD Le Sean 20111325,Rem: 3 of 46 Atal Carmonmaice nope ics te meta say seme tts ie ey toes ei a aire. P= rons Gora ‘no Creer yn sae 38 Satoh set Sted ESTER vee oe romarena serene ura anon? 'A Acectonton salt be detected by FISHIN 8. Areoproca 1415 tansacaon 3) CC Paracertse mraon noting amazon 167% 1 Boheme 15s rate ater KS] 1 8 € fam evresores 15 re tan heater A) Tis chidhas Pras sym (5), a contin characters cincay by neonatal ype ‘creme nypapraga wacng (eras obaty an ome pel dees melt, shat tre, Sak anes anaeotmypogansder ana cheat nee Gente ay, PAUS ns Sasa genome "mpeg reang em amereclten on te pte ctromosoms gt regener Rom matoma unpre {Seay Tar sh chamesemes 1 are nratatomtne mae an one ne ar nether ‘feos Seenams inrmaon ome pseal somos Ts ae Thaugnapainms denon =the mest omc caue of PS, woullbe etecod by FSM. To neoal PH deeeabadhare eas hat De ave of coease Ui trl iomaarel isn 15, (chee A) hi a techiqu vedo dette presence or boone of poe DNA sequences on whe fhromctemes. ean delet sequences a ara a 00 bbases ands common Used asec PWS ‘eeafngammesogeltonsin pala hemocore 139 regen (chee B) Recracaluasocains vai the exchange of gent mata between two rarhomebgoue fromczemes 1/48) isnt how cause PS,Rem: 3 of 46 Explanation: User: 280147 Tis chidhs Prater syndome (5), a condton characters cincay by neonatal hype, freme nypaprags mscng'e mars obey ans smsti yp des min she reek anes ance mpogansder ana cheat nee Ganteay, FAVS ns Sacer genome ‘mpeg rauing em a merece one ptenl chromosome gt fener Rom matoma unparral {Seamy Tuer sh chnmesemes 1 are nrattomtne maine an one rere nr nem ‘hoas ecenaos vomanon rom mo pateral cromosame Teast. Thougha Paloma denon ea mest ome cause of PS, woudlbe ctcoa ty FSM. Thonenral PH aceenbadhar deaos athe fase of bea es ant omar doy 1, (chee a) hi a techiqu wed te detect he presence or boone of poe DNA sequences on whele fhromctemes. ean delet sequences a ara a 00 kbbases ands common Used asec PWS "selingmmicredeleens in fe paenal chremosore 159 vegan (chotee 8) Re:racaluansocans ino the exchange of gent mata between two rarhomebgoue fhromczemes 1/48) isnt how cause PS, (chee ¢) Paaceric mersionsareinarsins of chomosoma DNAin ane am the ehamasome at ‘clung he ceromere, Pracerste masons mcvomosome 1S have ben opted eee eye aus oturan daeaee, (chotee D) Pama ungarental disomy 15 causes Argenan oyndome,adsease caracoized clicaly by Ietalretauaten,epey tema’, ou mao ad guage cevcpet a equate ard cing veto! objective ‘hokey cnc featusef Prade- Vl synceme are ont yptona, ereme hyperphagia and rad Sbeaty sho stare sands ane ard charles odes Pre Wess fom ama {np len 15 eto amieredaetonin he 15 fen the pao crvemosare Time sper 105 seconds 8% answered coecty ast pa (77200) ‘anni © USMLEWORLD Le Sean 20111305em: 4 of 46 A Lyearld Caucasian afer rom antehyrshinvkng he eersorsrtace of Mars (0 the Hsmatie has ahsioy o 9 SSEERSASTSGRREERREEN sina ops ros htt reveal cnet he folaung changes patent” ' Coblesene morse and ensure iformton ) B.phy of eisai BM) casa nea wr europa 8 1 Macrptones wih acciwitea PAS-poste aes 7 ute adenematous pops (1%)em: 4 of 46 explanation: User 388147 eta asease ao tamed cea spre gen senstneerteopay) cua caeon caused ‘Setar exposure to heal lai and teed ras in suscepbinaas Ts eS to gute cn {Mgpe auuimeane eactens nhs gesvoiesinal vac ats bnthe sma bowel celocdsrase mesers as marks vlusavophy na balarund of dsc frtersCO8™ Teal hrghaetes ae esl este sarace een Wha wie are Fray eels (604 ellhrptocts, cma cle, macrophages, cosoghs, amas cls) ake Ub resdence tela prota hntnosin, sia dense prserts as a condin called "damatishepatirmia* Groups of enibamatos, lana pages devep one exencrsutaes ee ews, kaos, butocks, and back. These ‘tremely pure sonar caueedy the cossencon og g@ andl snide wih eich, 8 mean athe nish acho te eodemal basement mantra ote cupric crm. Nees ‘scrtenl estate crest of ral mirsbaceszes te deal paplay tps, Greta fe Imteaboesoeoceloceofom sabepseal bls (choles 4 €, and D) Coolstne mucosa ansansusl lamar af teatro Cbs Sone, Mead eyhana and neug?ivatn ee smal ave ate rarspeate tgs sac clea ‘aha ruttce ecard, neusrgwicious cals ard aternaay Sowa dsease.Uaeregrages ah ‘Sccumusa PAS gente andes ae conser wih gps dese. aegh al theaecendtens an taser th aes hey ack tong ger cenpotes and af nat assed Wh eral ash (hole) hpi adenomatous pops ae cen discovers on ovine conescpyin oes heathy Pabers_Frumerous,adeneratos ops cane conons such a al dereratous povpose (FAP winch nas a Sion gerae cope bt aosoon wih ica ash, cational Objectve: Fhe smal bowel els: doease presents ao marke vias avophyn abel dtse eas ‘hes cel scae presers as demabishepeliom a cendcn lich Sal Mefosbcesses a ‘ect pplay tps evry coleceo arm stbepacna ses Time spere seconds ss answer cone ast pas (1722012) cap USMLEWORLD ILE Sean 2011130295rere nie talowrg st deserbes the changes neaac muscle cts responsbe fore apy ‘args? "Fiat acy) 1 6 B High ate ot moor ment snes 9H Lpctrce gelesen att 2X6 O. Hoh te of colagn mRNA syrtesis 75) 5 card capaci) Baplanaton: seri: 388147 ‘Thewal ete gh vere (RY) alent Zemin eines, ature mck han th he at verte. narra heat the RV Diekness 5.4mm dtr dastok, as Sean te han he [atc dase (acura cn) Ths, hs Sporn eons aes Ag wethcua ypesopy UE) Cartons are ternal diferente cleat an r longer hie. Consequeth cro ‘tonfenon oh heats mecca ad rece mnereaces mensn ond mass fhe Me Earomyocte fe hyperrery) The fypetee ate eased Uvough rereacesin trae oprah Sass, he iy pete nd the quar of sarcomeres and Mtohondra wih each Earomyocre Gore presen iat wihthe ges esponable fo el earn: reopen Upreguted As the hear makes lager qari frames gow cos man mRNA & aesized Sotecerrae (chee A) gh te of mist actus sen when ol nubs are ceasing (edn pele). Theta undoes ypateply te yperiatia when expos weasedhatodnar ads (hole €) Lipsstn gan accumuston beng inng associat winnresengcl age Mienot Fetocton of hyperiss rypeery. (hole 0) ih reo colgen mR shess an ype colanen depostn appears tobe assed "roca iss. The eat shown Be mage bore does Retort Sipe ossrere 2X 8 D. Hah rt of calogon mRNA syrthesis 7) Explanation: User: 280147 ‘Thea ete gh vere (A) eaten Zemin theiness.andemaresy noker han that he at Arr, inal ear, he RV ces © rm dung aes andi teary ens an hs (Wat dung ast (reand tem) Ths, hs cpacien monster erneuar ypamopy FH) ‘erat the hears mectancal ua resus cresoed en snd ase he nc aida (ryt). The pervpne se exaloned rough rereassin eae of prin Sn the qu pean athe qty srartes ant nacanta atn eaeh {ace "cane epessn a res the genes exporter aa eari: Seeret SFist ute a on on A ee (hole A) non ne of mt ats sen when cel numbers re neeasha (crn eras). Theft unegoeshypetephy te ypeiass when espondng to weeasedherodyrar aes (Ghote €) Linsuscn grande accuratoni abeign finding asseciod wihncessngcl ge. Miata Feccon of hypepiasa ypeery. See eee (hole) Caria ct apptossis assets with soph of the muscle issue, which woud rest Iranies' smal ean cational bjectve: (Croac hypettopty charactrzed by aninreased ect mjosn mRNA syehesis Time spore 4 seconds 69% arsed oct. Last upties 11102011 apni USMLEWORLD ILE Sean 201113025,rrr we prc wt er oN ne He RRS) S864 ecm 2.0/0) Beco) Eiplanation User: 380147 The sins conposadat aspartic stated squsmauskeratnized opt (orto allo the ‘iereer vo RABI. 5.86 ec x8 0.0185) ea) Biplanation: User: 380147 The sins conposadet a cpa stated squamous keratized opel (orumory calle the pdms) anda depe’conmecio eave lye commer calod he demo}. The pbs and ers ‘toeck dong basement membrane boundary tha septs he epiemal os tombe deal Poptoe The fr yrs ee eps, rom he moa cupric lyr he dope! nye include ne rau comeun,svaum lucidum, svaum gandesun, svaum sresun, ad atom basse Tho statu corneum is mated by’ in the dagram above, ans ypcaly composed iteenotmenty [yer of ead squmovs celal ack ce hese ala we sha ey are ropace ye mi tnt ote seam basde a sttun aprocum. The staum comeum &genrlyhctet i aa ‘habuoy conmaniy exposed oi of Wauma eb le fea). A paras adatoal chen lhe ‘Sau come cals" ay occr acaba peated exeral pressure ar Wen (holes B.c.0, and =) Te cacper nes cine eens (7) We basemerementeene (ne Ses ("snd paces CE") coat heken oom caus nvespanae aon Wau veal objective ‘Reals causes by aclenng of be mest Syperca shinayer, he satu comeum Time sper 53 seconds 0% answered comet. Last upties 11102011 cap USMLEWORLD ILE Sean 201113025,Rem: 7 of 46 As year iy ner vale cha moor eile sccider. Her avareewe show an hago &> Tis pater’ condtionismest ha asscisted wih cereasadlewels of wichet the flora? Xe ALIS v0 FSH Bom) Protec Areosanecone 7] Tesosterne (2) Thad strain mane)Rem: 7 of 46 Xe ALES 6 FSH BOR] Pokctn 1) 1 Acetencone Tesoserne (2%) Try suai amane 35) Biplanation: seri: 300147 Paheyste ove sydiome (PCOS) ic an endoein dsc associ wit ho sbnomal roducton and Inetatlam of snogene and estoge n worn Character eases ole dace nlale {rronrhca ebesty, autem, ves, pail aun essate, and jsp. Physical Stamnon alte alected oes demons bce elgaront ord creat Tucano capes. Ck Secons vel aubeapeul flies dere slages cl auese. Hype: aca Guomalcal nm te rested oles. Tho snondatn and incensed entopen lvl seen ia PCOS at that eccur whan oan hea calla ‘erence creased simu om hghteele of eres eran mone (The onan bes fete thon procuce ger uate of andioganscuch es twutetone and anesenedone. Because ‘ate stmulnghomene FSH is decreased nproparon ei De otan ganuess cel ate une ts ‘emi he arogen lo eaogens. Aneabon foie Foo eseacedesopn ew (holes 4.0, and Hones LM andosteneoe, an estettone are characte ef PCOS. (Chole ¢ ane F Prascin ant TSH ees ae namalin POO cational anective: {wr low namalevlsc FSH and aigh LAFSH at retype aang of poet ovary syrome Time sper 6 seconds 5% answer comet. Last upties 11102011 capi USMLEWORLD ILE ean 201113025,em: 8 of 46 Aa years Cauccan mal fers rm meni reaction an mkray mover, He re es Nc ipeantngipn, Ura we sean hgh hhh long es oy "A Adsnosios arin 4) 8 Adeaneprosporkosjranserase 2) © C.Hporartine gunn posotonbesytencteres (87%) 1 Pare nuctoote poophontce [8] arti oitase ] Explanation User 286147 “Te cncalfeares descr nthe vnete we characte of esc than syne, whichis an Inte ecessie dle n hypoxanthine gare pespotbositasfease (ASAT) Tis onze bartcpace nines sae poy by erage comerson of porate an guanine 0 sre menophsthae and gare roghecae especie Oefeenay fis enzyme causes ereacd pute sabaye,hetesed pune snes, hyperemia peter, Cerateit Elnclfestires noe se rating behav (cassia gearing) eral ean Frou movererts, delayed moor developmen resrloss and gow Parra may ase ep a “Yoat ante sin uner fer alectedchis apr dvetohypeure. Teme wih apart creases une acd eels andere reeves Spams rete gat en uel, Dts eae Fas ite ec on rerclogeal smears (holes & 8D) Oriciency of aerosine deaminase (ADA) causes atosomalrecessive severe combined fmunefceny ScD), ADA parcpiesn pune calabm n tie sosene of ADA th fencenraans of aA a-curulte resign hhbton ef foonuchedereductase ad ieeoe tion {FDA srtess and eo deat Purnenuclosce pospranase (PN) Is afer ent m Be pure Eatapatsm paiva, Stee of ts rayne easton Sele -yrgrecr ete Bayport ‘ancton otem: 8 of 46 Tho clnicalfeatresdesrbedin the wget ae characterise of Lesh Wan sycome, whichis =n Inia ecesavecfctin hparantare anne esponbosjransierzo (HGPRT). Thi erayme partcpaee ne pure savage patwayby caaangineconerson et hpararthne an panne 0 FRosne menophsprats an ganas monophecpat, especialy Defeney of sane causes Sereaco pune savage, nevaate pune aes ryprurama a ypereura, Charset ftncafsties nse "et running eso (omen ge an ip bra) ris tal eas "vatriay movers, delsjed moor Golopmen repress nd gn Prete may as repos “fost onthe sun under or steed cds duper duet hypenre a. Tresment wh sloped hereacos une aod lvls anatheretere even spams rooted gat sn oleh, bts eset Fa ie tc on reuclogeal smears (choles A.D) Deine of aerosine deaminase (ADA) cases autosomal cessive severe combined ‘rmunedeleeny (SCD). ADA pte plsin pune calablem Ine doonce af AOA hgh fonctions of GAP acura renug n bton el nbonsueuoductace wd teres ehiion SF DNA sees and eo dst. Puro nakoade posphonlase (PNP) sare enzio ne pu, fatablem pave, dtiency obs rayme adato an ued T ergot ect Biymphocie ‘ancton tla (chee B) Adee shacphrbooytranstrase APR) is anata enzyo inched input sae: tis Feepenatie orth comerson of denne fo AMP APRT delvency eau m hyparuncerta al ageing one woltiass, APRT cocenc i arsed an adosomafecesanashon ard does a cause ewelogeal scars (Chole £) Xanthine outase cones hypoxanthine xanthine ad thn sartioo ure ai. Kaine bodaseaeene resute niypareema eresed vane ets and tration nays Sone. ean! obecive {Enceynan ature san Xn! aoe causd by dfceny of hyponarin uarine posorbospranstese HGPRT) res n hyperemia ah ypericr, ih enseves cause Fepem and got as wel as S-muang tenon (asset ap Dr md mer ‘eat volar navererts and dled mtr eevee Time sper 22 seconds 57 answer cone ast pa (77200) Cann USMLEWOLD ILE Seam 201113025errr ‘Anew substance sytesze nthe berate never so the 308 subunit of prota rasa. [Asai reaming arinoe:yHENA acoso mAs Bock ad ot Sytheass A. The ‘on hana substance emne oma wre te loa? 8 A Byvomcin 65) 8 Rann 96 C Deneve Be © cHoranphenee 5) E Puonyen(s%) Diptera oan) Biplanaton: seri 388147 amazes amor ot sine ty on oss ne aac ais Baca have {Huns) ose sic na ra rye tan sje tne 305 rosa sauna ae ‘eicjetnes og dey) athe aranegheondes (9 Stepamyjen).Tetacjlnes ae baltostahe ‘pubs ost se neaing Mycopesinepoeunonae a wel sick an canals ‘Aer beng tothe S03 tbosoma Start iacyelnos bck he arnaary RUA em ae ‘osama eee ste, (Cholees A and 0) Enron ta mactalde sbi at nat te SBS prekanotie rasa abun {bulbs raseson sep by peverung urease fom he dere ste te eg a ‘arsatan Sia, cherampnantal tnd oth S05 prcanonetheseal auburn becks, apusensterane on, thereby preven new pte ban ation SSemieton incu anticestomnnaetaceralrescurce rangntews ave er and frees manrgs caused 1 maneyas eH tereerrr opteta oan Substancs tein ptcn syrhesisy prokano riosemes ate abel arbihcs Gata have ‘oSreesomes wih 508 ae 305 swunts anereashurars have HOS mesemes win 60S ané 408 Suns). Those antes het Pet prokaryote poten sos tthe 308 nosema sub cude he ‘ercyenes ep doseyeine) andi aanegveeses fg arepomyn).Teacjehne me Datos ‘obnoes ost sen eatng Mycoptaems preuronce aswel Reka an chalcone ‘Aor ong tothe 30S reosomal suburt tacjelnos bck be arnaaey OVA om erg he ‘somal accept st (holes A and 0} Enron ia macialie sbi ht binds tthe S08 prkanotirbosoma ubunt tu blocks he vansbcaon sop by erovertng Ruska fom he der ste to opto bot fermaton, Sint, cheramphancol tnd oth S05 prekarjoteNbesemal abut andes penesvesletae acon, thay peers rw pepe bo oman (cholee B) Réarein Bock prkantc mRNA syrthesiby bala UA pabrease. Typiealy weed in Comeinsten wih cher sticiests masse bore reactance lampn ues acive ube and protrts monngs caused Hmong cH rane (choles €) Pusmycins an artanleosde atte thas a rue enous to arise RNA In {he prota lends ta he remaire rlase ours pohypentdechane Ss poppy puonyen {choice F) Oprmeratoun nts pte synhesi a eka ces tough ADP rbasyan on ‘engaten acer (EF2) E-2catahoes he vanshcaon ct froving pages char ang ROK. etna! objective Teacyines an nighties nt gokart poten sess 35 nbosoma swan teres eyovoryen and corangrencal nab potayate pate yeas a he 5 sera Subua. Time sper 28 seconds 5% answer creat, ast pa (77200) Capa USMLEWORLD ILE Sean 201113025eee \Whatigpe fags rls eo dflereison = progener calia dennlca? Xm A Grow aster 68) 8 gob 16%) 1 © ©. Tansepton actor 26] 1 Gown act eeptr (178) ribosome 2] Eaplanatin User 286147 hhembryenicdeeepment the zy bepns as single cel hat dies util foal cls the body. Thus, tis atotpetrt som cel_ Each phose of onan matyaten ges en rogressvel Moe fetilzedissies Asa aver col became: moedifecttate loses Brpolecy ie aoe oie ereratonogresses 35 lbw: {2yete— Morus — Erenebist— Epblast— Mesaéem — Dera Ce Tho combination f calls erent story an aos teal sal crest wanerion ato rent ces thors exgession ef en those goes equred focal perfor turchon. A ‘ils cezin he haran body psones he ere gene. ascrgon crs pec each nak ‘seve alow ony hse gers rele @ a's Spee pe na nebo abe epeseed {Chole A) Gut tet ar pons et ste he groh and trenton acu cline, Unis by taganing sass srensengten actors Exams neta Gl CS ana POSE (choles 8) Cyeleos area dese gop of rots used incl sigaing andere ommunieston Groth factor are oat of ne (choles 0) crown factor ecatrs transite he sala ctr by ha eeponding poh factors tino nt arety raise progento cel dereanen A inca recta sam a gout aeeee Explanation ser 266147 hhembryenicdeeepment the ct begs ssn cel at dies outa female ces nthe bos Thus tatoo sem cel_ Each phase of onan mateten gress io rogressvel More Speczedissies. Ava ger col becomes mae dette, loses Burpee ie sabe owoed erertaton ogresses 25 ows ‘2yete— Morus Erbrblast + Eilat» Messe ~+ Dera et Tho combinaton f a cals eect istry an aos eteral sal crest a waren actor kuin the ates te foorsexgressn of ny thoes pees requred fet cela prom ttunchon, A Fula clin he harman boy posoees he ete pence, Vang fc pectic oeach nda {Sov alo ony hose genes eee aca’ ope pe andtincbon be ogresoed (chee A) Gout fact ae pon at hue he gout and deri of us cline, ‘oly by foguaing yeas ef Varocigton acts. xargs weude OM C3 ard POSE (hee B) Cys area rere go of rots used incl sang and rc fommuneton. Grow actors arene pe ot xn, (hoteeD) cron fat ecptr insta the snl debered by oesponding oth ators, [ito not ret rguste rogentar cel derebabon. A cincaly recvart exangle of owt ace Feeetri the eprmal rw act recep EGR, EE, HER), whch is ovetepraaed ncaa mmaigandes (hole) tosomes re cmposedot our derent BVA ecules conbnaien wih osama Pte. heytuncon ie vansine neo ten tld et epute cella aercrtan cational anetive (at ateertatonsdtermined by he vanserpn facto mie win an ul cet Time sper 28 seconds ss answered cone ast pa (77200) Capi USMLEWLD ILE Sean 201113025ener ] ‘Animes is sug te eet fares ras onthe donenaed ee, Tho expermertal nds re Somer be rah babe CO conte Buon ous x ‘rug Xs moet ka tbe which fh flora? ‘A aone 4] % 6 8. Physostgmin [4%] 6 € Plane BOM 1. Prenyinne (7) Tino Explanation: User: 280147 Te denoted ey demonstrates ite play responce ig euting ni mimal ceca rece tytn parereamats posgangion:Pauens atinnenathe plan sete ofthe esl For Drug Xt eauoe pully cnanedon me daneneee oe must be acrenarnee geht aeety Seite ne mstsnne eeprrs cine soon mssns tte puplan sper Pisses ne such ret encinerge museonni pontener 1. Prenetvne Tao Explanation: User: 280147 The denoted ey demons ite ppl responce ig, euting narra ceca race brine prereset: posgagionerauens atinnenatehe pny sneer ofthe esl ne For Drug Xt eauae ppl cnancoon me danereee oe must be acrenarnee ger Nae cates ne mbesnn reegtr ne smaon muscee ate pupa spncer Pigeons sane such recente ruscanne aso (chee a) Avpine isa muscu recep artagoit andere coud ot cause pila cnsictenn Sonenaed er. (chee B)Physeagine isan ndectchlegeagerst. To have en ett onthe pup hia ‘richoinestrase itor needs ehh ease am he parseynpabwt peeoanlane none unr Daneraton a he eye howerer minimizes a such ease (choleeD) Phang i an alo area ecole agate ~ <2). Consequcnty, enephne oul acide a ects he ada mule of oe, cause puplay dln aoa concton (Choos €)Tinallis aman elective eta bake. Because pully consicin i mil medi by thuscarechanerge rece nd pula aton mary meaes by a acenerpercepere 26a Hocker wouldnt aematealy tect pup darter However iebata becker cous tt cep ted cy mc rea raven cepted shen age ar atonal objective reat muaeanne rang: agents such a plecarine can cause pupa consicton nthe denervated oe Time sper 72 seconds 20% answered comet. Last upties 11102011 capi USMLEWORLD ILE Sean 201113025,errs {Segut tact sn Sheed ol nen ke a Sand wfororl agee and eye red ich {Wie lewn mos bey seprodiced tue pte? wa ctor] 8 caine ai 10%), 6 €.Geatn 208) 1 Seren] x8 € Cuca 5s) Fvaswocve esti pie 155) orcs aor candian hough arse fom he mune mediated destruction of gst mucosa Dvorimo is eamogerosuts nchone sophie goats, a canton charceraed by bss tains ‘eco secatng panel cls. ProftundhyporRrhyane devecp, lean oneeseed run pan vas (Grea G cal gas sereton nated yhyrctione ace). Once rumba ef pare cole tice opted ard heres of am 8, craved perciusaremiamantets WS ard smoloms such as anemia, les, ftque, apne sss patestesa, meshes, end usteady gat 5 Stennis pate (Choews 4B, and Levels of uni ractr, gst ace and sete ae uw n es wh Pemciae saema-hatced apne gests (choles E and) cucsgen an vasoactive tesna petites ae pay unt y percus Semannducee atop gests rum cied soph ase associ wih pcan nypachonyara art cessederrs ‘rie teu is most iy ovepraaiced tis pater? wif 8 cate aid 10%) © ©. Gesrn fo) 1 secret] 8 E GucononB4) aovactve resin pote 6) Explanation: User 288147 eric aomiais canon hough arse fo the rmune mediated deste of gst mucosa Over imo ie camogerosuts nchonc apie gas acondion chaacerzedy bss theo ‘eco secratng prea cls Profound hypochhyana devacr, ledge nceaead sun gern ves (aaa G cal gai secreton reed by hyrctione ace). Onee We rue of paket ole “Scepter he ores tn arenas pecs aremismantets wth SI ae ‘mols such as anemia lus, ftque, soph: east, arses, meshes end tad Ga Stent pater (hotes AB, and D Level tint, gti sc rn sere rw inl with Pemciusanema-naiced aophe gett (choles E and) cucapen an aso tesna petelees ae pay unatece hy percus Semacnduced stop gusts veto! obecive: Fema arcrninaiced apc gas is associa wih proud hpoeyaiad cesse Seu gas vs Time sper 73 seconds sts answer cone ast pa (77200) cap USMLEWORLD ILE Sean 2011130295eerrr |n.28-year mal foun thave 2 esd scretal mass ding an anal pha eration The nase padi when th pad tts, bul Ssappeare when eles conn Tension ets ane When fe fcboung ee ost hey dogs? 1 Spemaioede 2 X 6 B.Hysecde 114) 6 C varcoel 60% 1 Testu eaner (108) Tester tron Explanation: User: 260147 \atcocls ae cates oft spermatic en pampifom lous that vl nthe it cru of {Som orasihmaes Vancacalstng tn sno one ae beemns he nrenn vee eorpeaaes| etecnthe sora andthe superormeserone ate thereby neresarg he presi win he rena “nin ths preture mins gansds ven sce erenaes restr nea nt are a ‘etegrace bod fon tarde teste on stnarg._ hen ecurben poste Is ssumea uch ofthe $sograumstesyeme ereten anstmvrezse mmenesi aes Thevencaei Congres = 3 ‘ominaihess or a0 lage compresede ase ered bag of worma Same nua fe Seymplomae, via cters expenencesehing an ehved win eeumbarey, asta erophy Wy ‘diced bythe mnernrease nso teroertueoredea ly (choles A.B, D.ande) Spemascls,ydocls tsi cancers, and tsetse ae nt SSminched wih ecunbarey. Spermaocde are cate masios hat so rahe cap ao ep, ‘ppealy measuingbelwoun te and ve cerbmtren dametr Nanna speataels dent eause Sprotane.Fyotses se perkncl ud colecone ht accurate between ha parla wesrl Byer oheunca vagal Hyaocee canbe sal or ute age pan and dbl tosong th ‘hemavs ae. The fad wie te yc easy Wansdumnted. Testu cancers the meat ome sold tuner in oung wren, yclypesettng ae an, aries maos tht dos rat {tmatlunrte Testor totacn smal hn een fete ad toy, presen wth cee pan atereerrr me rysccae i 6 C Nicolo) Testa cancer 10) Testelrtrsn \atcocls ae cates oft spermatic ein pampinflom las that vl nthe et cru ot {Suh at asuknaes Vecoceletna ta ano one te becuz he rrana ve is ompresaes svesnthe sorta andthe super eset ata. thereby neteasa he presie win te ea ven Inu tbogreacuren ele gonad vor doo eveone, esa valet ae ard "etegade bod flow tnatd he teste on stra. When ecurbert poate saci uch ofthe ticodretumso sytem crcUsten en tho varicose rorches ace. The vance can reer os min ues: aoa agecompresebe nase edo a'bag of wana Some nua ae ‘Soymplomat, we cers epee aching pan ebved wih ecumberey ashe opty (ky ‘dod by be mre nrease nso tamper) of educa ely, (choles A.B, D.ande) Spemascls, yocls tesiedar cancers, end tsetse nt SSminched wih ecunbarey. Spormaocde are cyte masoos that sco ema capt ao ep, ‘ppealy measur belwoen te and ve cerbmtten dametr Nanna, spemataesles dent ause Sprotane. Foca se perkncl ud colectone hat accurate belwoen th parla ward Iyer ote nea vagal, Hyco canbe srl or ute age apn and dbl tossng Wh ‘hemavs ae. The fad wie te hyve cacy Wonstumnated. Testu cancers the meat. fom std nee n ung aren yacaypeseng as air, pariess mass tt Goes at ‘tanatunwie Tester mgs en een neue ar oy, pesrng wih ae pan ae tense pyaar mr Wauat the ests atonal objective ‘aroceles ae ttn ote sperma: van pampinorn pleut eae win tana andres sg oun Time sper 25 seconds 0% answer cect, ast pa (77200) Cann USMLEWLD ILE Sena 201113025errr steels Caan ra conan ost and eps: sacomion yea fesmnson ees an an jon Gai eoscop it Spores ahahafasemaigancy Miho he own eae hoy case thes changes? 1 Pea-ieghes sire [19] 1 6 B.Acatoss igicens 73) meas melon [55 2.8 0. nereftromatoi pe 1 FN) Farm adenomatous past 4) Explanation: User: 260147 -Aeanoasngneans i areaeve shin candnchrstenas by rows lack vty, tke pages ‘tater to aes nfl eqane soem ane sun crack ence Reaons gnc est foment assecisoawin beng anders sue a ren resistance or bec). Hower, bs cen fEanenon tan sen sonal he reste ot marae mnths parontesna at en oman Fs) tugs When aantosts gress appears suede, qc sresés 1 mies the mucous memtranes cr pas and sn tolkanood ef rabneneynceenes nes been posites that mabey and Femara coun cannons ngpeans by rtueneig eum fe positon (chee a) Petz yes sora rare ator emia ease characteraed by gman Imuceedaneous macles and haartanatoe pols nthe Glued, Progressive growth canteed io Inaignartvectormaton {hole ¢) Mlanemas ae asymetomate opti ions, pial easing mre han ne cetinetarin Samet Maed pron vardbity may cur, ih shades of Back own red navy Bs, ray Frese. The borer ae eaueyiroguat ad ache. anor most len spa’ oo SB can so aoe in the esophagus of atastanae oe er (cholee D) Nowctbromateistye |e characterced by newofbomas, cleat sol, and pigmenterrr Explanation: User: 280147 ‘Acarnasisngtcan isa reacbve sin canon charaieiod by rewnts lack vet ckened plagues ‘favors a aes nfl eqane soem ane sun crack nace Reaons gree est ammo sseecktawm benign enahans suena nsun resistor ee. ser sn fananon tan sen non he resents ot akan wnntnegaronfenina at en somaen Fs) tugs When aantotsngress appears suede), qi sresés 1 mes the mucous membranes er pas and sobs, tolkaood ef mabey nceenes nes been posts that mabey and Frpermautnerna cous ecarihsi geans by rent euth rte rosin (choles a) Petz ghee syria rare atosoral emia dees characterae by pigment Imucoetaneous macs and haartonatoe pops nthe Glued, Progressive rw canfeed io Inainartvetormaton (cholee ¢)Msnomas ae ayrpomatc or prt lesen, cab measuring more han ee cetintaria Smet Maed pron varGbiy may cur, th shades of Back, brown rd navy bs, ray Preset. The borer re eauey ior ad alte. anos moat en appa’ os, can $e oe in the esophag of atastanae oe er (chee D) Nowctbromatoistipe 1s characterized by newer, cleat sot, nd pment ‘ie hanaromes, Newufeeonas al ude magna degeneration a cad maar penperal nerve Shesh trar (holes €)Famial aderamatovspoposisis an scan dana nde characterized bythe goth 1 dozens calanealenematous papa. Same parts deveop bengh entartesia anfesaar fe, Soave ters oe stn, heptcblstanas) The pahps etal progress lo cobtetal ance, veal objective: ‘anos tea sist conten associa win beng canduns suc sain reste of soesty Hewever fis sn conden can so son the presence o malgracies wane astoniesial ‘ost, stomach, er ong. Time sper 750 seconds Ta answered coe ast pat (0102010) ‘apni © USMLEWORLD Le Sean 201113025eerers ‘A Thrmbonane nor [12%] 2.8 8. Geogr ior 4 (Autor it apo (105) 1 © Banik etagoit 2) Tisueplasmnogmn awrtor 8) Explanation User 286147 echorcl eaves require here anicsoadtion postoperative sents wih mechanical aris ‘elves aro ae isk ators for tomboerteli on ai nit, ecu rte. Frperesaule sine) longterm ane aeglen wth arts mantan an Hof? fie aces ‘eearmendain. Warbrm estes by antagariang real yeatbonton warn Kdependent coting {actors Ure racionsed hepa, waxy canbe ken aly onan apatert bass, wich pat ‘vite anicoonustofchaee hee (hole A) Artal therapy anes inaceqt protection agate trombsembee compeatons Scsoctad win achancal hast ahes. The odatn ef ow abe espe (atvertonane yee oie) {Saran ergy e Cass recarenerdabn. thew apn srt scat adc capdaton wih ‘warn 4 Nar Gacteasa there amoeba and reauces motaly fom oer cardovastua, dosaoes, (hoee ) yeopatan ita nts se used npr ace coronary ym (hole ¢) Hepann caval achaiesarthvonbn I. Most experts recommend heparan in the Fess postopera ped un waa tes eect Because hepa sans sibc UUs termes iso ana che me auger sing,eerers 1 © Byori arapuit 2%) Baplanaton: seri: 388147 Mechanical eaves eure vnc anicoaston postopera patents wah mechanical arte ates ad no avert last Dvorboerlsm (ana to, vert dstatcion, ypetcoasulable sates) ag tm atcosodien wih watanto marian at Hat? 0351s acs Ieearmendatn. Warn eperses by agony rata -cafboniaon af ann K dependent ang ‘murat pu arate na caper be, ep tite andcoagun of tec ere (hole a) rte therapy are sraeae protection arte tiremboerba: eompeaons ssoced win rechoneal Peat ves The afte on-oze asp fa ertosane thes to) {Owaran ferpy 9 Gs recarmeranon. adhe astm srt 2st radeon Wh “ror ther eceases the kof rember a esses atm oer caves ht ‘Seomes (cholee B) scopotsn bila ahibiors eo used inputs wth cue coronary sys (Chee c)Hepann ety setae arenorbn I. Most expr econmand heparin ne {rma postoperative psig un wara aes eect Becashepuma snnsred sine aneoisy trian, eno ana che ne ptr eng, {hole #) Trombones suchas sue plasminogen attr pete comers of pasminogen 0 Blasmn resutngin he ccavng fens eon cts Thambaice are net usedo peer et ation atonal objective Hehancal eaves equre cra anicoasston postop. Warn, an tr tama Sepencert rng acer syanesasthe ape of ehice mips ppc Atle eta Wh Spin maybe wed auc, Time spore 6 ecorts 2% answered creat, ast pa (77200) cap USMLEWOLD ILE Sean 201113025errr ] ‘ROF ea le th pple ode is ost corps seve back fa. The pa ok "eee y rest and wales in tnt. Lon a Weare hs pare roloe NOUS resin vei long? 2m A erence pany amane ees) 1 inpared ster yates CC nparedesostrne conversenintarat este 5%] 1. Decreased ercuatrg tests 52%] Teetoserane rector down segusbn 18%) Explanation: ee eae Trae Li fserrr a ‘Back pan uretevey rest patent wih fem posit ase stony sugpeste frost cance, ‘nthe bac pansigaing the preseice meta, scat esr he veeboe Laois {tr of androgen depo hap) used nen wih advanced pose cancer AGE ag, upoiae has apn papi when amistad ns pusaie fasion a attajeas apeies when sami ‘nurse at antago, upaie Caos og tm edctan a cicuang estastrone keels (reiting in made ocr by Sereaay rea’ ult an eeaseat uentargramene {th T tater aya cel esond ta helower ies ty prduengless tester, cause Spotoumciy a of ey aagrasndposiae care canes ae andogenSepenoet, lee Vest sen prong su, elearg bone pan ard edueng serum PSA (Chole 4) Communusiang em aamnton oleae bs ruta gan lease a FSH an Fesutng recuedtsosronepeducon snd ete (Chole 5) Atnoun sume sna studes supp tha euprode yet BES enzymes edn ‘esleuar serogeness, cer suse aer een mechansr {hole ¢) Fee testosterone sees bythe toplasmic enzyme Soesuctase to em he mere potent Syarestserone mpenoera age bss. Leoprloe does at ht Soveaitase (hoteeE) Lvov dosnt seat wm-enue testasttonerceparsin angen cesponaive {estes Ar arson for 1-14 day,onever euros oes Gow equte Gr recears on Spaadavonn cel ne pty gna. FSH and LH reas ete reverie, esuirg neonatal Stppresoon aetna! objecive: {nga conanus ayolde admiration na male nhs Lease ndtherctereeststerne reducon, ruin a-meacaleretony” Time spore #2 seconds 52% snowed comet. Last upties 11102011 Cann USMLEWORLD ILE Sean 201113025,eer bhembryane denlepmen! bothmemnasites and game unerga whckal he flown? sponse) 8 Weal 8 Cnn (90) tapes Anse) Eaplanatin User 286147 Durathe r roe mors of erbnore dewtopmentrecurser melas mgt fom tener crest ‘others and hen fe epaerc. Once esalahed rte cps epee cle eee ro. TelenocesHerfte melnosnres area” wehnte roc feel epider at tf ‘eck of ean ape finan fo he sues othe poster ok sas primal germ call Sarit the geal fej ang te hard sth weeks oferty: dovaoprert. (Uke melaoctes, gem cls Way {tom femigaton ode anda weston mofo ngs tues whch acco ete Sevcnpment elroy ar gem cel irersin nsec) A gente gem ess unerm> raerevs moses anther met rly aresia as pray oes nme Hephaee. As Unrated spermatgaa, th germ cols prac basl compare wi sore ing iso Primer speratcres {holes 4 B,D. and) Meanccis and gem cls do not tp nego apoptosis metas, hrpertoty or arapsa srng roa etree devecprent. However est ses ay be observed Other isues. Fer nsance erence fate fgets an les fequres Be aortas eG fete nese gers. Eenjone reaps is sen ie gcocriacdied aepearace of Fetes win heparcteas. Card npeoohy ay deveopin he faust a dabebe mane Las, ‘lens peal naa, afaloscan ase Meron Skea mS eves eaangto FRascomyosarcomaeer 18 C Miran 9) iro E papas) Explanation: User: 260147 ‘urge rt roe mort eran delpment precursrmelnats mgt om the neural crest ‘oho ces aden epic. Once esalaned rte cpr the pecrcor cle aererate rio. Ilaecyes, Herfate mlaooors appear wEnnhemlaecjes fe fetal ep by Bert tn esis ol gestion age (rca tom he ecu ofthe poster ok sac primal arm cals Slr gto the gen fp sung he fh ard su weeks a embryos dewtprert. uke melanocytes, gm cls may ay ‘fom raion oe and ke up reacens mcf omar tees whch accout forte Sevebpet st motos ar germ el uatcin usu cso) Aa oye te gum cels undergo ameroue mses shen ati, rly aresty 2 pinay oejee nme Repose. As Undorrttes eperatgzna, the germ col rte baal compare wih sore igi primary spematocyon. (choles A.B, D,ande) Mencia end gem clo de nat pial undeoe apoptosis, metaplasia, Iypettopty of snaps dng rand embry devaoprat. However, ese ales ray be observed in ther tues. Fer nstance enone arate egos andes Yours he porta evening fete nese reg Enbijone meaplaale sean ne ucocoiad ned appearance of Pepatoyes wine percees.cardec peony may develop nie uses debe moter. Las, ‘eet anna ter, anal can arse nembiane seta muscle, ey ar IMencnmyosarcoms veto! objective Dung rama emaryen cevdcpment mecces mata the neu es othe peers an germ elo mitt rom De ok oo he onal ae Time sper 71 seconds srs answer corey ast pa (77200) cap USMLEWORLD ILE Seen 201113025errr ‘aire wih ai abromales 2 ARTERIES ha 2 ABERRATpr to ctromosame Ball Winer othe parts eaaac sruchres was moc asymatemegin er? 'A Prive vec (8) 8. Prive aa) 8 C Tn anaes 72%) Sis verosis (6) canal veins 1) Explanation: User: 280147 DiGsege syndrome (055)ie picaly caused a ton onchrmasome Zt 2ihat ects the {matin ete branchial rch ana get vessels drng he four woof ambnyegenese. THe cine ‘eats cf his sytem es rom te ata developrant fhe tra ar out herrea pecs [whine he procncssas of he tyrus, paayron gone, anaheubrabrercha a). carcequnty, ‘uss wh DGS hve delete T calimodateg runt scenery an sboet of Mpepeste mus, ‘ean secandaye absent parr gnde, nt dtects ne hart nd oat ves Conomneal sta detect ar gt emeanin nfs th DGS, antici pasta neu stones, troy ot Fat, anaifempted ere ach, Persctrevuncusarerbsve concen mich Binge get esol aos rom be hear, he ata, pulmenar ates coven ate Manchin Sie he acerg segment ths veel (ermal, naburcus ateons dvdes no, oprah othe outa and pulmonary ate) (choles A and) Whieavericulr spa dls cesta acsoctod wih persist nunca ‘Moros, the pone verte and ponte eta arent peal oa acted n DOS. (CholesD and E) ht, te snus vrwsus is acon at aches Hood fom he taline vn. the trael vn, ad te commen cata ver. Evel toe crear sus sd obi va he [et atm adhe aus verarum height The cada vans eu toed rom the torial lserrr Sn vernsus 5) canal veins 1) Explanation: User: 280147 DiGsege syndrome (055)ie picaly caused a ton onchrmasome Zt 2ihat ects the {matin ete branchial rch ana get vessels drng he four woof ambnyegenese. THe cine ‘eats cf hi rome eso rom fe ata developrant fhe tra ar out herrea pecs [which he processors of ne tymus, tatoo donc, andthe ubrcbarchal bot). carcequnty, ‘uae wth DOS have detect caltodated runt second oan abo of hypolste Oyu, ‘any seconde aboot purty ganda, and dtc ne eat and gol vss Conarncl ctw wat dtc are quteconmonin late wih 063, and inca persist rca ‘ores tao stat andtempted ere ach, Persclrt vuncas arabs aconahen mabich Binge gat oso aos rom be her, he ata, pulmenar ater covenay aie ans Sie he acerg segment ths veel (ermal, naburcus ateons dvdes no, oprah othe outa and pulmonary ate) (choles A and) Whieavericulr spa dls cesta acsoctod wih persist nunca ‘Moros, the pone verte and ponte eta arent peal oa acted n DOS. (CholesD and E) ht, te snus vrwsus is acon at aches Hood fom he taline vn. the treel vn, ad te commen cardinal ver. Evel toe crear sus sd obi va the ‘eta ar ne stus venrum ete igh aun Te ada es eu eed fom he stdaral was ‘ute Vetan bodes. Nonect hese Scares is coreeny mean OSS. veto! objective: DiGeege sree charactrzed by tym aes, pert apts and ca and ea vesse Sects Te buteusatenoausts common malas usa, esi ersten wre eran, ‘egy fa rug sri orn Time sper 24 seconds 734 answer cone ast pa (77200) Cann USMLEWRLD ILE Seam 201113025eae i oe pee Ayana gue 5 an 1 % 6 Cll aro 8) 0 Digkanasc oH Wo a0) Explanation User 286147 'stpe swithng sa mecharem by wich shige 8 cel clone can express rious erent shear han ‘Snes ht share ancertica arabe dest ing (VDI regen The ees te edton oF Srubedes wih he somersTow arigeriespecfey bt wth aerert elect uctenaty. Nave rare fate praduce bh in andigb wth eral Dd (angen bndng regions. Che> oreo by anne. Foworer hese 8 cle wllstipe owiehe ete gonratnn of GOA nan Forisatpeswictng occu, avo sal process ms ake ace. Sia | causes heaton of ‘raccrplonat frie regon nie eve, rey cting fe te spe 2 penser onthe Coad on cols a causes DNaswch recorbnaten.Terelre, an x had Setecneexreson of CD40 he oul be une engage spe snitch rer al "BD 1S BA, rig Conseuert, Ns. narod ees wal elon atonal obective: IBenpesiching sor arogen-achated Best crete gS, WA aE fer he nal ol ant aD veces Time Sper 4 conte 78% anewared cont ast updated (1272010)ee rr Araceae cles homoceal DMA a pl nl several tgefrgrens. One fhe agent hz Shh’ metiieyocne carter Ulich the alwng trate bet acres Hs grt? tie aosayassocaid wah Ao 8 Ris asteteriRNA stb) © Cothaslow ancerpona act 86%) 1 ns unwount ar epeaon | oy Explanation: User 286147 I ton frst the enzymatic akin ef meth groups cose resves nthe {enone Cee guanine Grutaieepex semen ate prefeettall methysed. Genes wih Fehsiedevesineeadues ae elec slerced. Aopenratly 1 ef he huran gore mehysed {Zany aver pontine Meise sbefeed py aele nsec genes eared ern Sicerted sora cels. can ao be pstiebse fe cxarelenmalyrarces whe or Sparesser fees we droge by sbi meyaon iv metrrserces prom OA rethien. These enzymes can minmehysted ens ira Diver by sh hepa stord as ator ca au atin of doe tnd NA Ieynen 'sconscered apart he eed cede eae lm of ere epuen Rt aro Changes mth genet code se (hole A and) Heterochromatin is tht packedONA associ in histones. The DNA win tetooctromsin snot acto wars Echoman surmoins Oa ooeeassorated win tones {fatconans gees ste beng rans. Ceres pte ro eetocrora a patert el e ‘Sian poste rio heteocrometm date a, akg heros treratn pate pene code are (choles 8) ais srtheszd itn tents by RMARchmeras|ee rr ‘i metaten frst te erzysti ain cmt gous esse resfves nthe Senome. Cee guano drucesi repeat agiencs ar poteortallmtsted Genes wih Freed cyosne readies eo cece slnced.Aeponmay 1 he huran geome © methyted {Zany gven ortinime Mette isbateved ts ply le nslna gnesretequredby tmnt ‘reted somate cele. can azo be panooge er kaolin malgrancs where tumor Sppreaser ens ave dovrvegued by steve medyston ‘iv mtyvareraoes pom ONA nyse, These eraymes can man meted ens eng Div epcton by usin the parent stand 2s atte cay outa a dour sand NA reyes concord a pata he epgentc cede" aaa am f aro reputon hl lar cn ‘hanges nthe gnc coe el (Chole A and) Hetcctroman i ty packedONA associa wan hisones. The DNA win Ieterectvomain snot ctv} uarccibed. Examen is uound DNA boca acco wih toes thatcontans genes act bang arccrbed, Ceres paclad rio ectoehomatn ater cl ‘rian pcked io tcrecromtn dave al malaghtrtamatn pat th pene code sea (chee B) hic steric win be nko by RIA phere (hole £) U”radaton damages ONA by rng covaet bands between adacert primi ees ‘ere ering jleuaatepmane ames or pelos, aetna! objective Div meta sences gene warserpon ani patie epenetc case. Type, meyers etch incjose une aruceaie ep soiences Time sper 168 seconds 050 answered coe ast pa (77200) ‘apni © USMLEWORLD Le Sean 201113025eer A Hesamnase A) cocaine 4%] © egabctsaco 6] 1 singartnase 2), Arouftae 08] 2X. F Glucose shusthatas demeronenasel 13%) Explanation: ser 266147 Gauche ease the most commonlysosomil strap iscas and heros preva genet sort tra Avera Jens Tes cone schaacitze by gucoerenrosce depen ne hsesores of Inacaphanes erat, sc aceebosce (i sce om fe panos ef serescreaces En eytoctes) suerte ro fs base cose andi cemers by Gucocereroadase. Whente ococereoroscose ere oncrrrsome 12 sulted Foweve,adelrerey ef gucoceeoase Seveops. Macrophages caled Gaicher cls lite od gcactesrosde hd assure epperance Sf wine tssue pape. as seen fe ae ore Cnc raresahons of Gare disease ie Fepaosenoresayanema irortecyopen, Deeing, stesperea, tore pa, ard bre actes (hole a) Tay-Sachs dsease tan avosomalecesse,newodegereraive cen conmranin [Auer Jews, tiseaused by adeeercy of heosamniose Aan cheered hse feenor of Gre gangiose. Weaess ssf metr ss, nee characters chen re aca veep ang eae (hole ¢) Faby seas isn inks ysosuma sorape doeac caused by decioncy of egos, ‘shen resite n eosemai serena yoephinganos, Clneal manfesaonesopest i chihocd as ute cevere oxvernty pan, decreased abit seat, core ara change, gasroiecral act Stic, and rpeworatoes {holes 0) temare Pek eas tpe Ais auecoal recess, ysosoma sorape dead cases by Sphngurinace ciency “Sphraenyein hn securulsin hsosores. wth feces nase Sevepng prury sonornalreuroge fencien. Oeah ects ty ber ae Yea feeer {posserorascae ans on chemacome a2 = masts however Secure et uecowetrosace mvp lcrpnanes aed Catcher cls l nine pd gussetrorad id seme sppenanes St wen tssue paper, as seen te mage sore. Cinca rarestatons of Gavhar deeaca neue Fepstoapenoragay, anemia rameocyopona,beoling, stoopena, tars pa, ard hoe rectes (Chole a) Tay Sans zeae an autosomal cease, nsrotgeraraie cendtonconmanin [ronan lous. tin essed ty adenenney ot hsneamnare hss chrsteeaty hoes ‘onsen ss Gro gagionge, Wsimese hes ct metorss ana the charter een re maa ove ang reaey (chee c) Faby disease is an eked ysscmal rage cas caused by deicne fe glacesidse, the reas vowel tron ol gcosphngeipds. Cincal manesions appear in chided an ‘nce seer enter pan decreased aby tose ced ad rar change, gastortecbal act Sytincten and rpcvorioas (chee D)Nemare-Pck seas ype Aisa atecomal acess, Ysosoma soap diode caused by Sphngornelnace daicancy. Sphrgcnyein en accurullsin hcooomes, wth afectodinds ‘evap proud sonora neuro uncon. Death esl by boo vee Yar of ge (chee) otacematc ukodystopy i on autosomal ecessve,Yousural storage dsr caused by ‘ysufaane A olen). Cecroade sulle accurules as aresul Aected nud Gomenarale peeral european mater dicutes, Oesth pal occurs yea auhood (Chole F)Oucose phosphatase dehycgenace deine an Xn dtd charactrzed blow ‘ves of gtatione nf reuced im, eam re bcd clare wareabe to cate Sressts Symptom nals pial preset wt ate hera¥t nem an reat unde veto! objective: (Goucher dnease se most cmon yoo strap disease and characte adele ot ‘ocoercorecase. Macrophages Caled Gauche als wth he Ip gucoerctrosoe and ssunehe eperace of weed tasue paper Time spore 45 seconds 454 answered cone ast ipa 1057201) Cann USMLEWOLD ILE Seam 201113025eer ‘Aster mal bout othe ER wah ropes oioies ot EORTC. The parts {ngtered and campians ef danecs up Saning. Hispac radical NS sot saat Hs Hone preva stone a ating. Whchel flowing substneos most ao Reumude nhs yest vascular soot musics? Aca I 8. cuP 61) inst phosphate (P20 0.23-bephnsphgherate 2-876) [0] 2X0 € Sacerasimananne Sit) 6 Biplanaton: Evinephine (a)eer Explanation Erinephrine (as) SRRARA RATATAT ES Proce Yong ££... | poe ‘Teper esrb n mis gets ost hay experencing ask upper gastos! Peerage 5 haenced yh cate gourd ee arpereion.nan fa t pevet eur fare due Fypoviema be patois sympa neue stem ras ncteased tne tay era ‘corn andthe staan envy, The two er med he sympa atau 3st ‘eepone ae epee and nrepreniie. These ones /erovatans cin ys ‘Sherergic cal suse cepa. The arene fecepa fesporobe tae onwecbn an ‘creas bod esses e prt energie recepbt. The apt atlenege recep uncboay ‘te lntlaposphae() second messenger system In aon whens caechasrne bese aharo ed ig catego rligionins etait poctascmiay tree aan ea Se ‘reponse me apnepn ndnreprenene. These rane: /nerovanant chon sain ‘Sfererge al zuface cepa The arene fecopn tcp fate onkaren and Fereraty bod wesaret heighten recep, Toe spt atenenge separ nto by {heim npg (P)secnd mescenger sytem Ih aot when seechasrne se fe ah rece a6, pts strates at aces proshoipaseC, whch tum reeases Pad ‘ever (OAS rom meméranephospolps. Peres sored races caleumrosutngin {hole A Gye Ps secrsmessenge ames flow ssn cece Wed to, (ctl) prot Gz poten acral acerecctce Aden eycac ave ATP ofr cycle [AIP wnch en octnaee per knase Aor aces cfcts Ths phy aciaed wih shan {icin srenrge recaps and eral ter meres sur a guragon PTH and ars (Choice B) Cyc GUP the sacond meszngefo aa naire opie and ni xe (O) hace sande setae a specie G pain hich ham acter gui ela remangnferrtn f 20> an GtP. Te itecchise ots erie’ vate saraon open mae & (Choice D)23 BPG ape byproduct ef yes prodiced meld cells nat sch muscle Ele. Anperensen.3 BP wl creacsthe deer ef ongen a he zac eh he heen ongen sociation ceo re rah). (choles) Sit is prodicedbycanfenston ofmeticrine wth ATP_ SAM frei s 9 meth eu Soot od imohed sever eacns requ meth rans. teary ten, SAM reaued {ete conversinet nee a cteprie by Be ez phenethodomine NW mehmnstease (Pa) Ts enyratcreacien pedir occurs madera meds ois upegused ty cro, veaonalobective: ‘Sulton ef ah feceptorsy nrephehvne fm the pos ganic spate eves wi cease Promthess