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15. The MC variant of the pre icteric period of viral Hep A - Flu
16. The Mc variant of the pre icteric period of viral Hep B - arthralgic
17. The most informative biochemical test- in prodermall period viral HepA - Enzyme level
(Alt,ast)
18. The pathogenitic mechanism of jaundice increse level of conjugated bilirubin, cholesterol
and alkaline phosphatase → intrahepatic cholestasis
19. The presence of anti HBs indicates -past illness caused by HBV/vaccination.
20. The syndrome most typical for the pre ecteric period of HepB - arthralgic
21. Typical changes in blood in viral Hepat include everything except → increase ESR 22.
Typical changes in level of bilirubin & its fractions in vital HepB - increasese in conjugated &
with moderate Increase in free bilirubin
23 Viral HepA & is characterised by all of the listed sign except - Chronization of pathological
process
24 Viral hepatitis E is characterised by - severe course in pregant women
25. What biochemical tests show cholistasis in Viral Hep - alkaline phosphatase
26.What biochemical tests show cytolysis im viral hepatitis - Alt,Ast
28. What biochemical tests show mesenchymal response in viral Hep - thymol test
29 What Changes in biochemical ....nonicteric form of viral HepA - Increase transaminase
29. Reducing of liver sizee during the height of viral Hep B - massive necrosis of liver
30 Routs of Hiv transmission are identical to - Hep B virus
31. Severe course of Viral Hep & is typical for - pregnant
32 Sign of cholistasis in Viral hepatitis are - increase cholesterol and Beta
33. Sign of Cytolysis in viral Hep are - Decrese prothrombin index & ↑ ALT
34. Specify duration of pre icteric period in typical form of viral Hep A - 4-7 days
35. Specify mech. of transmiss. of viral HepE - Water borne
36. Specify the leading ….. jaundice in mild & moderate form of viral Hep → Inflammation of
bile duct
47. The following biological fluid of Hiv infection. ..... HIV concentration - blood
48. The following , enzyme is found in human lmmuno Virus (HIV) nucleus- Reverse
Transcriptase
49. In what period of acute viral Hep A is pt. most contagious - prodromal period
50 Incubation stage in HIV infection most often last - from 3 weeks to 3 months
51. Informative biochemical rest in the prodromal period of viral HepA - enzyme ALT AST
52 Kaposi's Sarcoma in HIV infected is associated with - Herpes virus 8
53 Leading Syndrome in acute Viral Hep - Cytolysis
54. Long Term presence of HBsAg after Viral HepB. - the process has chronic
55. Name the cause of hepatocytes cytolysis in viral, HepB - Immune response to viral Ag
56. Name the differential clinical criteria of VHA from HBV in icteric p - deterioration of
intoxication
60. Name the prognostically unfavourable biochemical in viral hepatitis - Decrease prothrombin
index
61 Name the reason that in the icteric period of viral hep the urine becomes dark - Conjugate
bilirubin
62. Name the typical Clinical sign of cholestasis in Viruel Hep - Skin itching
65 Presence of the following disease in a pt. is an indication for HiV - Toxoplasmosis of cns
78. For Hiv infection. serological Diagnosis at 2nd stage - Western Blotting
79. For which glycoprotein of HIV CD4= proteins serve as a receptor - gp120
80. HIV Has greatest tropism to - T
81 HIV is inactivated when boiling during → 1/20min
82. Hiv infection route of transmission - parenteral, sexual, from mother → fetus
83. Immunological markers of acute form of viral Hep B except - anti HBc or lgG
84 In HIV infection Serological Diagnosis by ELISA…….- · total antibody spectrum against of
hiv
85. In HIV Infection Serological Diagnosis by Western Blot method - Ab to separate HIV protein
86. In viral Hepatitis the mesenchymal... Increase of - thymol test
87. A reliable sign of virus replication in Chronic viral Hep B - PCR +VE reaction
88. After acute viral Hep B in the past in serological blood - Anti HBc IgG
89. Antibodies to HIV in the infected person from moment of infection - during 3 month in 90%
2 Student, 28yrs old, fell ill 2hr... palpitation in epigastric …… no diarrhea - Gastric & intestine
-3 A patient who had just..... stool is profuse , watery without mucus and blood no abdominal
pain → Cholera
4. A 20-yr-old pt without mucus and blood no abdominal pain Main cause of diarrhea - impaird
(CAMP)
5 A patient with intestinal dysfunction…..no abdominal pain …..anuria - Isolation of path
6 Two adult patient…... hypovolemic shock III degre, convulsion→ 5% glucose sol.
7. Patient D, 89 years old, has watery feces may... Tachypnea, muscle cramps Uncompensated
hypovolemic shock
8 A pt. was delivered... abdomen painless... stool k involuntary, watery - Polylomic saline
13 The pt is 25 year old sick for days....Th a " Grid "eye developed - Bulbar
14 A 50 year old man has hospitalised on first day …. unpleasant foamy - Administration of
saline
15 The general conditions...sunken eye temp 35 complication - Dehydration shock 16 A 28
year old man fell ill with an ….. bloody mucus mass… spasmodic - Bacterial examination of
feces
17 A 34 yr old pt. White yellow plagues... Sigmoid and rectum - pseudomembrane colitis
1. the most common form of viral hep a===icterus
2. the main criterion for hep b include all except ======incresed thymol response
3. the outcome of viral hep b except====liver amyloidosis
4. the characteristics of hep b include all except =========dies quickly under influence
5. the mechanism of transmission of viral hep a ======fecooral
6. leading syndrome in acute viral hepatitis is=============cytolysis
7. in the peripheral blood in acute viral hep b .exceept========neutrophilia
8. in the stage of early convalescence in…….except======hbeag
9. cholestatic syndrome in viral hep .charact by ==============hyperenzyme alt ast
10. for viral hep c ………except ===mild course of disease
11. the most unfavoourable for patient is ======combination of chroni c hep with delta
superinfection
12. changes in hemogram in acute viral hep are==========leukopenia lymphocytosis
13. the terms of dispensary observation after viral hep a ==========1 times a month for 3
months
14. the average duration of ip of viral hep b=========50-180 days
15. the clinical sign of mesenchymal ..except=====anemia
16. in the pre icteric period of viral hep b ……except ========anti hbs
17. bio chemical parameters hep b and d are except===========free bilirubin prevails
18. transmission of hep b virus mother to fetus ………carried out =========intranatally
19. the main clinical sign…………..acute hep d in carriers of hbsag ==============all of the
above
20. the incubation period of viral hep a ====7-50 days
21. immunological markers of acute viral hep b except ===========anti hb c or ig G
22. what biochemical test …………….cholestasis in viral hep ============alkaline
phosphatase
23. pathogenetic mechanism of jaundice……… increase conjugated bilirubin, cholesterol
,alkaline phosphatase activity=============hepatic cellular jauundice
24. the clinical symptom of acute liver failure except =========reduction of liver size
25. the feature of delta virus…except ============the virus can multiply on its own
26. the most comon variants of preicteric =========1 2 3 4
27. dection of ab to hep a virus of the ig g class=============about the chronization of
process
28. sign of a threat to chronicity with acute hepb ==========high replicative activity of hbv in
mild
29. the most common variant of pre icteric of viral hep a ==========flu like
30. transmission of hrp b from mother to fetus =====all of the above periods
31. for acute hep c the course is most typical ====acute cyclic
32. the most common variant of preicteric variant of hep b=====arthralgia
33. the earliest laboratory indicator of cytolytic syndrome ====increasing activity of alat
34. the manifestation of cholestatic ………..viral hep is ========increased cholesterol in blood
35. presence of anti hbs indicates ============passed hb v or vaccination
36. after the onset of jaundic ein viral hep a, patient condition ===========improve
37. for viral hep e , everything is typical except ========parenteral way of infection
38. sign of intoxiacation with viral hep b =====all of above
39. the manifestation of cytolytic syndrome ….in viral hep is .===increased serum enzyme
activity
40. the source of infection in viral hep b =======all of the above
41. the typical changes in blood ……except ====increased ESR
42. the syndrome most characteristics pre icteric viral hep b ======arthralgia
43. clinical signs of pre coma in viral hepatitis =====tachycardia, tremor of fingertips
44. biochemical parameters of blood serum ….except===
45. which variant of prodromal period not typical for hep a ===mixed
46. the mian mechanism of pathogenesis of deltavirus ========direct cytopathic effect
47. the main markers of integrative chronic hbv =====hbeag ,hbv dna
48. hep a virus refers to ===enterovirus
49. the most common variants of pre icteric hep b ====arthralgia
50. acute viea; hep a is verified=====detection of ab to hep a virus of igm class
51. what biochemical test reflect cytolysis in viral hepatitis====alt,ast
52. in the stage of early hep b…..except ===hbeag
53. morphological changes in viral hep a except=====necrobiosos of hepato
54. signs of cytolysis in viral hepatotis =======decrease prothromin index and inc alt
55. features of preicteric period of acute hep b and hep d =====all of the above
56. cytolysis syndrome in virla hepatitis is =========increase alt
57. what biochemical test ………viral heptatis ======alkaline phosphatase
58. informative biochemical ……..viral hep a=======alt, ast enzymes
59. the most common outcome of viral hep a ==recovery
60. hep b virus =======dna containing hep adna virus
61. the following are used …….etiotropic for acute and chronic hbv==============antiviral
drugs
62. in chronic hep c , course of disease is =====progressive with severe clinical
63. in the preicteric of viral hep b …….except==============anti hbe
64. the laboratory criteria …..increased risk of chronic viral hep b …..except ======alat
65. the main criteria for viral hep b ……..except…=======increase thymol response
66. the preparation for ….cholestasis in patient with viral hepatitis======ureodeoxycholic acid
67. for viral hep a is typical except============chronicity of hrpatits
68. immunity in viral hepatitis is======================persistent
How many types of Toxoplasma are there?
1. 5 2. 1 3. 2
2. In the organism of intermediate hosts, Toxoplasma can exist in the form of:
1.bradyzoids
2.ocyst
3.trophozoids
4.tissue cysts
1. Trophozoids 2. Oocyst
3.spocyst
4.sporozoids
5. Tissue cysts
1. alimentary
2.airborne
3.vertical
4.pin
5.parenteral
1.airborne droplets
2.congenital
3.sexually
1.cellular immunodeficiency
2.chronic form
3.sharp shapes
1.Encephalic
2.visceral
3.Lymphadenopathic
4.Ocular
1.in 1 trimester
1.hydrocephalus
2.calcifications
4. aniso-orbital syndrome.
5.osteoporosis
1.virological
2.cytological
3. PCR diagnostics
4.Serodiagnostics
5.bacteriological
12. Serological markers of congenital toxoplasmosis 1. detection of anti-Toxo IgM in the ELISA reaction
13. Specify the duration of the course of etiotropic therapy for congenital toxoplasmosis
1. 3-5 days
2.10 days
3.4 weeks
4.8-12 months
5.21 days
14. What is the duration of treatment for the acute form of acquired toxoplasmosis? 1.1 cycle of
tritotherapy
3.spiramycin - 10 days
5.amoxicillin - 14 days
toxoplasmosis
1.pin
2.transplacental
3.ascending
4.downward
17. What are the reasons for the frequent damage to the eyes and brain in early toxoplasmosis fetopathies?
1. Yes
2.No
1.in 1 trimester
1. 2
2. 1, 3, 4
3. 2
4. 1. 3, 4
5. 2
6. 1
7. 1
8. 3
9. 3
14. 1, 3 15. 1
16. 2
19. 2
20. 2
Tests. Lesson number 3. Topic 14. "Congenital HIV infection"
1 retroviruses
2.adenoviruses
3.cytomegalovirus
4.herpes viruses
1.HIV-1
2.HIV-2
3.HIV-3
4.HIV-5
1.boiling, disinfection. solutions: 0.2 hypochlorite, 0.5: formalin, 0.5 Lugol's solution, 70 degrees
alcohol, 6% H2O2
3.freezing
4.100% alcohol
3.genital, insect
4.airborne
3.sexual contact
4.parenteral
3.pregnant
8. What fluctuations in the incubation period are most often observed in HIV -
infections
1.from 1 to 16 weeks
4.from 1 to 3 days
1.CD-8
2.CD-4
3. CD-3
4.CD-124
10. List the most affected cells in the body in HIV infection
1.T-helpers, macrophages-monocytes
2. obese, stromal
3.epidermal cells
4.neutrophils
1.5 years
27 years
4.life
3.incubation, AIDS
14 is HIV mutable
1.Yes
2.no
15. Which HIV envelope antigen interacts with the receptors of the target cell
1.gp-120
2.gp-30
3.gp-41
4.gp-24
1.syphilis
2.Kaposi's sarcoma
3.pneumocystis pneumonia
4.CMVI
17. What pathogens of HIV do you know and what is their resistance in the external environment
1.HIV-1 - resistant
2.HIV-2 is unstable
18. What are the most complete reasons contributing to the possible activation of the provirus
1.taking medication
2.vaccination
4.exercise
1.one
2.two
3.three
4.five
1.T-lymphocytes
2.eosinophils
3.monocytes
4.B-lymphocytes
protein specificity
1.env
2.gag
3.pol
4.LTR
1.gag
2.tat
3.env
4.LTR
2.gag
3. LTR
4.env
3.perinatally
2.when breastfeeding
3. by airborne droplets
4.fecal-oral route
2.Nucleocapsid HIV
3.HIV is captured by fragocytic cells that carry it throughout the body and
4.integrated DNA of the virus into the DNA of the host cell
1.has regulatory genes responsible for the activation of the provirus in a dividing cell
AIDS is
acid-stable α-interferon
1.1000L / μL (≈50%)
4. <200L / μL (<14%)
1.6 months
2.1 years
3.2 years
4.6 years old
indicator diseases
1.Kaposi's sarcoma
2.systemic vasculitis
3.Sjogren's syndrome
1.anti-nuclear factor
2.antibodies to cardiolipin
3.thrombocytopenia
37. What is the most significant feature of the hepatitis C virus leading to
1.shell structure
2.variability
3.transmission mechanism
3.macrophage tolerance
4.chemokine tolerance
Ответы
1.1
2.2
3.1,2
4.1
5.1
6.1,2
7.1,2
8.2
9.2
10.1
11.1
12.4
13.1
14.1
15.1
16.2,3,4
17.3
18.2,3
19.2
20.1,3
21.1
22.3
23.1,2
24.1,2,3
25.1,2
26.1,3
27.2,3
28.4
29.1
30.2,3,4
31.1,2,3
32.4
33.3
34.4
35.2,3,4
36.1,2,3
37.2,4
38.4
39.1,2,3
Questions to test malaria control for doctors of outpatient clinics and hospitals
1. Source of infection:
A. Komar
B. Sick person
B. Everything is correct
A. R. vivax
B. P. malaria
B. P. ovale
G. P. falciparum
E. Everything is correct
A. Exoerythrocytic schizogony
B. Gametogony
B. Sporogonia
D. Erythrocytic schizogony
A. 9 to 14 days
B. 12 to 18 days
B. 18 to 40 days
G. 9-14 days
A. 9 to 14 days
B. 12 to 18 days
B. 18 to 40 days
G. 9-14 days
A. 9 to 14 days
B. 12 to 18 days
B. 18 to 40 days
G. 9-14 days
A. 9 to 14 days
B. 12 to 18 days
B. 18 to 40 days
G. 9-14 days
A. Tropical
B. Three-day
B. Four-day
G. Ovale - malaria
D. All
A. Tropical
B. Three-day
B. Four-day
G. Ovale - malaria
D. Verno Bi G
10. In what time frame from the onset of parasitemia in the patient's peripheral blood appear
gametocytes (homons) in tropical malaria:
A. 5-8 day
B. 9-14 days
B. 10-12 days
A. Febrile and unspecified for 3 days during the epidemic season and for 5 days during the rest of the
year
B. Patients with ongoing periodic rises in temperature, despite the ongoing treatment in accordance
with the established diagnosis
D. That's right
12. The period of carrying out antimalarial measures in the active focus of three-day malaria is carried
out during:
A. 5 years
B. 3 years
B. 1 year
D. Correct A and B
13. Groups at increased risk of infection requiring special attention as possible sources of infection
include:
A. Migrant contingents from endemic areas (refugees and internally displaced persons, seasonal
workers, contact specialists, pilgrims, tourists)
B. Servicemen demobilized from the Russian army after serving in the endemic countries of the CIS
B. Crews of aircraft and ships flying to tropical countries and countries where tropical malaria is
prevalent
D. That's right
14. Negative blood products are stored for:
A. 1 year
B. 6 months
B. 3 months
15 During the period of treatment of a patient with malaria in a hospital, blood products must be
examined three times in case of three-day malaria:
B. Daily
16 During the period of treatment of a patient with malaria in a hospital, blood products must be
examined three times for tropical malaria:
B. Every day from the 1st to the 7th day from the beginning of the specific treatment
17. With the disappearance of parasites from the blood during the period of treatment, control - studies
are carried out during:
18. When infected with tropical malaria, a person becomes a source of infection after:
A. 3-4 weeks
B. 5-6 days
B. 10-12 days
19. What type of malaria can cause a severe course of the disease with damage to the capillaries of the
brain and death:
A. Tropical
B. Three-day
B. Oval malaria
G. Four-day
A. Febrile attacks
B. Hepatosplenomegaly
B. Diarrhea
G. Anemia
A. Zheltukha
B. Nausea, vomiting
B. Renal failure
23. The development of coma and death in tropical malaria is possible during:
A. 2 months from the onset of the disease
A. Malaria coma
B. Ruptured spleen
D. Hemoglobinuric fever
A. Malaria coma
27. Early relapses of malaria are possible in patients who have undergone:
A. Three-day malaria
B. Tropical malaria
B. Oval malaria
D. Four-day malaria
E. Any form within 2 months after the end of the primary manifestations
28. Late relapses of malaria are possible in patients who have undergone:
A. Four-day malaria
B. Tropical malaria
B. Three-day and oval-malaria within 6 months after the end of the primary manifestations
D. Any form after 2 months after the end of the primary manifestations
A. Seeding of premises
B. Use of repellents
A. Delagil (chloroquine)
B. Lariam (mefloquine)
A. Delagil (chloroquine)
B. Lariam (mefloquine)
G. P. falciparum
33. Among the 4 types of human malaria parasites, the most aggressive is:
A. R. vivax
B. P. malaria
B. P. ovale
G. P. falciparum
E. Everything is correct
34. The severity of the course of different species forms of malaria is determined by:
A. Age
B. Genetic characteristics
35. For the control study and confirmation, blood products from persons suspected of malaria are sent:
A. All positive
B. Nothing is directed
B. Persons who have arrived from malaria-endemic areas or have visited endemic countries in the past
three years with any of the following symptoms: fever, chills, malaise, headache, etc.
B. Persons who are febrile and not diagnosed for 3 days during the epidemic season and for 5 days
during the rest of the year
D. Outpatient and inpatient patients of pediatric and adult polyclinics and hospitals
37. In order to exclude the recurrence of three-day malaria, radical treatment is carried out with the
drug:
A. Primakhin
B. Delagil
V. Meflokhin
Correct answers: 1-B; 2-B; 3-D; 4-A; 5 B; 6-B; 7-B; 8-D; 9-D; 10-B; 11-D; 12-B; 13-D; 14-B; 15-A;
16-B; 17-A; 18-B; 19-A; 20-A, B, D; 21-G; 22- A; 23-B; 24-B; 25-D; 26-B; 27-D; 28-G; 29-D; 30-A;
31-A, B; 32-1-A, B, D, 2-C; 33-G; 34-G; 35 - A, B; 36- B, C; 37-A