Pharmaceutical Technology - I

Pre-formulation
Define preformulation. Mention the ways by which you can characteristics the drug? 4/5
How can spectroscopy be used to identify a drug? 5
Salt form of drugs has great influence on final product quality and efficiency. 6
Or, Salt form of NCE should choose carefully. 3
How can you choose a solvent system in pharmaceutical testing. 3
Define IDR. How can you measure the IDR of a drug? 5
Explain the effect of heat on solubility of a drug in particular solvent. 3
How can the solution stability of a drug be improved? 4
Briefly describe the physical parameters that can affect the stability of a drug. 6
Common ion can greatly influence the IDR of a drug explain. 4
What is melting point? How can melting point be tested during preformulation studies? 1+
3
Define hygroscopicity. How to set RH protocols in Pharmaceutical setting? 3
Define crystal habit. How can it be modified? 1+
3
How can the bulk density of the powder drug be measured? 3
How can you categories drug based on the compression properties? 3
How can you measure the compression characteristics of a drug? 3
How can you assay the powder flow property of the drug? 4/5
How can u determine the solid state stability of a drug? 3
Define polymorphism. Polymorphism can greatly affect the drug characteristics- Explain. 5/6
Briefly describe the physical parameter that can affect the stability of drug. 6
6
Polymer science 3
Define polymer. Mention its ideal characteristics. 2
Describe the classification of polymer. 2
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