CONTENTS Page

IMPORTANT NOTES 1

SETTING TIME AND DATE 2

User Manual LOADING A CARTRIDGE 4

PREPARING AND PRIMING YOUR PEN 6

INSULIN DELIVERY DEVICE
SETTING AND INJECTING YOUR INSULIN DOSE 12

For use only with Humalog® (insulin lispro injection [rDNA origin]) CHANGING INSULIN CARTRIDGE 15
3 mL Insulin Cartridges (100 IU/mL)
Your HumaPen ® MEMOIR TM may be a different color from the model shown, but it will work the same way. FINISHING AN INCOMPLETE DOSE 15
The HumaPen MEMOIR is designed for ease of use. You can inject from 1 to 60 units of any Humalog (insulin lispro
injection [rDNA origin]) insulin from a 3 mL cartridge (100 IU/mL). You can dial your dose one unit at a time. If you VIEWING DOSE MEMORY 16
dial too many units, you can correct the dose without wasting any insulin. HumaPen MEMOIR has a dose memory
that allows you to see the time, date and amount of the last 16 doses that were delivered including the priming
doses. DISPLAY MESSAGES AND ERRORS 17

CARE, STORAGE AND DISPOSAL 21

Read this entire manual completely and follow the directions carefully before using your new HumaPen MEMOIR. Failure to
follow the instructions may result in too much or too little insulin being delivered. If any of the parts of your HumaPen MEMOIR appear
broken or damaged, do NOT use. Contact Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare professional for assistance.
Fold out to see PEN PARTS diagram

R x only
PV 5381 AMP
Literature revised November 20, 2006
CONTENTS Page
IMPORTANT NOTES 1

SETTING TIME AND DATE 2

LOADING A CARTRIDGE 4

PREPARING AND PRIMING YOUR PEN 6

SETTING AND INJECTING YOUR INSULIN DOSE 12

CHANGING INSULIN CARTRIDGE 15

FINISHING AN INCOMPLETE DOSE 15

VIEWING DOSE MEMORY 16

DISPLAY MESSAGES AND ERRORS 17

CARE, STORAGE AND DISPOSAL 21

Fold out to see PEN PARTS diagram

 PEN PARTS
Cap Cartridge Insulin Injection ON Pen Dose
Holder Viewing Screw Button Body Knob
Slot

Foot Display
Needle Parts* and Insulin Cartridge* Display Symbols
PM
Time Indicator Dose

Outer Inner Needle Rubber Seal Cartridge

Needle Needle Plunger
Cap Cap Paper Tab Lilly
3 mL Date Battery Check
*sold separately Insulin Mark
Cartridge

ON Button Functions Dose Knob Functions

Push to: Push to: Turn to:
• Turn power on • Inject dose • Dial or
• Go to time and • Go to dose correct
date settings memory dose
• Go to next time • Change time or
or date display date
HumaPen MEMOIR Limited Warranty Manufactured for:
Eli Lilly and Company (“Lilly”) warrants that under normal use the Eli Lilly and Company
Pharmaceutical Delivery Systems
HumaPen MEMOIR will function for a period of two (2) years from the date Lilly Corporate Center
the HumaPen MEMOIR is received by the initial user. This warranty does Indianapolis, IN 46285, USA
not apply to HumaPen MEMOIRS that have been modified or altered, or
that have been improperly handled, stored, or operated.
If the HumaPen MEMOIR fails to function during the warranty period, Lilly
will replace the HumaPen MEMOIR at Lilly’s expense, provided the pen is
returned with the dated sales receipt. This is the user’s sole and exclusive
remedy for a breach of this warranty or for any claim arising from the use
of the HumaPen MEMOIR, whether based on contract or not, including
claims for breach of warranty, breach of contract, negligence or strict
liability. Lilly shall have no liability for incidental or consequential damages.
Some states may not allow the exclusion or limitation of incidental or
consequential damages, so the above limitation or exclusion may not apply
to you.
In order to return a HumaPen MEMOIR for warranty replacement, please
call Lilly for instructions.
The warranty stated above is in lieu of and Lilly disclaims all other
express warranties. All implied warranties are limited in duration to
the 2-year warranty period stated above. Some states may not allow
limitations on how long an implied warranty lasts, so the above limitation
may not apply to you. This warranty gives you specific legal rights and you
may have other rights.
If you have any questions, please call 1-800-LillyRx (1-800-545-5979).

The HumaPen MEMOIR meets the current dose accuracy, visual and
functional requirements of ISO 11608-1:2000 with Lilly 3 mL cartridges.

Humalog® (insulin lispro injection [rDNA origin]), HumaPen ® and HumaPen ® MEMOIR TM are trademarks of Eli Lilly and Company.
Patents pending for HumaPen ® MEMOIR TM.
Copyright © 2006 Eli Lilly and Company. All rights reserved.
 IMPORTANT NOTES

The HumaPen MEMOIR is a pen used to inject insulin. Read and understand all of the important notes before giving injections. Keep these
directions for future reference.

☞ The HumaPen MEMOIR is for use only with Humalog (insulin lispro injection [rDNA origin]) 3 mL insulin cartridges.
☞ Always prime before each injection. Do NOT use the pen if a stream of insulin does not flow during priming. If you do not prime until
insulin comes out, you may get too much or too little insulin. For more information, see Step 8.
☞ HumaPen MEMOIR is suitable for use with Becton, Dickinson and Company insulin pen needles.
☞ Do NOT store the pen in the refrigerator. Condensation may form inside the pen, which can damage the electronics.
☞ Do NOT use the pen and contact Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare professional if any of the following items
occur:
- Any part of your pen or cartridge appears broken or damaged.
- The dose in the display appears to be different than the amount dialed.
☞ Before using the pen for the first time, check that the pen is set to the correct time and date. To change the settings, go to the
Setting Time and Date section.
☞ Always carry a spare insulin delivery device in case your pen is lost or damaged.
☞ The HumaPen MEMOIR is not recommended for the blind or visually impaired without the assistance of a sighted individual trained to use it.
☞ The numbers on the cartridge holder give an estimate of the amount of insulin remaining in the cartridge. Do not use these numbers for
measuring an insulin dose.
☞ The 3-year battery life may be shortened if the dose knob is pressed without a cartridge inserted in the pen.
Replacement
HumaPen MEMOIR is designed to be used for 3 years. When the battery symbol starts to flash, there is less than 3 weeks of battery life left.
Contact your healthcare professional to get a prescription for a new HumaPen MEMOIR.

When you see this symbol (☞) throughout the manual, pay special attention to these important notes.
1
 SETTING TIME AND DATE

Before using the pen for the first time, set the pen to the correct time and date.
1. Press ON button to turn pen on. Pen will go to READY MODE.
1. 2. Press and hold the ON button again for 3 seconds to go into time setting mode. The hours
ON Button
number will start flashing.
Note: To go to the time or date mode you want, press the ON button repeatedly until the desired
2. mode is flashing. Pen will automatically return to READY MODE after 30 seconds of inactivity.

• Press and release to

increase by one.
TIME SETTINGS • Press and hold to
Dose Knob scroll.
Changing the hours
1. With the hours number flashing, press and release end of dose knob until
HOURS correct hour is shown.
Note: When necessary, be sure to adjust the time in your pen for
daylight savings time.

Changing the minutes

1. Press ON button again. The minutes will be flashing.
MINUTES 2. Press and release end of dose knob until correct minutes are shown.

24/12-
HOUR
Selecting a 24-hour clock or a 12-hour clock (am/pm)
CLOCK 1. Press ON button again. 24:00 or 12:00 will be flashing.
PM 2. Press and release end of dose knob to select 12:00 or 24:00 setting.

AM
2
 DATE SETTINGS

Changing the format of the date

1. Press ON button again. The date format will be flashing.
2. Press and release end of dose knob to select 12-31 (month first) or 31.12 (day first).
DAY FIRST MONTH FIRST

(Year Changing the year

flashing) 1. Press ON button again. The year will be flashing.
YEAR 2. Press and release end of dose knob until correct year is shown.

Changing the month

1. Press ON button again. The month will be flashing.
MONTH 2. Press and release end of dose knob until correct month is shown.

Changing the day

1. Press ON button again. The day will be flashing.
DAY 2. Press and release end of dose knob until correct day is shown.

Saving the time and date settings

After you have set the date and time, press the ON button to return to READY MODE.
The changes will be saved.

3

Always wash your hands before changing the insulin cartridge and before every injection.
1 Remove Cap
PULL
Pull cap off. If your pen is new or
does not contain an insulin cartridge,
go to Step 2. If your pen already
contains insulin, go to Step 5.
4
LOADING A CARTRIDGE
2 Unscrew Cartridge
Holder
Unscrew cartridge holder and
remove from pen body.
3 Insert Insulin
Cartridge
Check the new cartridge to make
sure it is not cracked or broken.
Insert small end of Humalog (insulin
lispro injection [rDNA origin]) 3 mL
insulin cartridge into cartridge holder.
 4 Screw Cartridge Holder and Pen Body Together

BEFORE AFTER
2

1
3

Use the cartridge plunger to Push straight together and screw the Make sure the cartridge
push the injection screw cartridge holder onto the pen body until holder is completely
back. it is secure. screwed onto the pen body.

Note: If the foot of the injection screw is not protruding as shown above, “dry inject” (an injection made with no
cartridge holder attached) until the foot of the injection screw protrudes from the pen body.

☞ Make sure the cartridge holder is completely and securely screwed onto the pen body before each injection. If the cartridge
holder is not correctly attached, you may get too much or too little insulin.

COMMON QUESTION
What should I do if … I cannot attach the cartridge holder to the pen body?
Check that the insulin cartridge is fully inserted into the cartridge holder. Then, make sure the cartridge holder is
completely and securely screwed onto the pen body, see Step 4.

5
 PREPARING AND PRIMING YOUR PEN

5 Inspect and Prepare Insulin

Rubber Seal
For all insulin types: For cloudy insulin only:
Look through the insulin viewing Roll the pen gently 10 times,
slot, read the cartridge label, and
check that it is the correct type
Insulin of insulin.
Viewing Slot
and invert the pen 10 times. The
insulin should look evenly mixed
through the insulin viewing slot.

For all insulin types: Swab the small rubber seal on the end of the cartridge with an alcohol swab.

☞ Any changes in insulin should be made only under medical supervision.

☞ Before each injection, always check the appearance of the insulin through the insulin viewing slot. Be sure the pen contains
the correct Humalog (insulin lispro injection [rDNA origin]) 3 mL insulin cartridge. The color of the pen is not intended to
indicate insulin type.
☞ Read and follow the instructions provided with your Humalog (insulin lispro injection [rDNA origin]) 3 mL insulin cartridges.
☞ Do NOT use cartridges containing other brands of insulin. This may result in you getting too much or too little insulin.
☞ For more information on HumaPen MEMOIR and Humalog (insulin lispro injection [rDNA origin]) insulin, please visit our
website at www.Humalog.com

6
6 Attach Needle
1
4
3

Pull off paper tab from outer Hold the outer needle cap and
needle cap. screw needle straight onto
cartridge holder until it is
completely attached.
Pull off outer needle cap and keep.
Make sure the needle is completely
screwed onto the cartridge holder,
and that the cartridge holder remains
completely attached to the pen body.

☞ Do NOT share your pen or needles.

☞ Use a new needle for each injection. Removing the needle right after your injection and applying a new needle right
before your next injection will help ensure sterility and prevent leakage, re-entry of air, and potential needle clogs.
☞ Do NOT overtighten needle.
☞ Using a larger diameter needle will make it easier to push the dose knob during injection.

7

7 Power On and Display Check
When the pen is turning on, you should see the following displays:
PRESS
Press ON button to turn pen
on. Pen will automatically turn
off after 30 seconds of
inactivity to save battery life.
8
PREPARING AND PRIMING YOUR PEN
2 SECONDS
You should see the
above display for
2 seconds. If any
part of the pen
display is missing
do NOT use pen.
1 SECOND
Then the display should
be blank for 1 second.
If any part of the display
is on during the 1-second
blank display, do NOT
use pen.
READY MODE
Time, date and 0 in display.
If the display does not
return to READY MODE,
see the Display
Messages and Errors
section for additional
information.
COMMON QUESTIONS

What should I do if … the pen does not turn on?

Make sure you are pressing the ON button as shown in the diagram in Step 7. If the pen does not turn on, contact
Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare professional.

What should I do if … I want to turn the pen off?

To prevent your pen from accidentally being turned off during an injection, there is no OFF button. Your pen will not
turn off unless the display is in READY MODE. The pen will automatically turn off after 30 seconds of inactivity.

What should I do if … a part of the pen display is missing or stays on all the time?
Your display is not working correctly. Contact Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare
professional.

9
 PREPARING AND PRIMING YOUR PEN

8 Prime Every Time Before Injecting

If you do not prime until a stream of insulin comes out, you may get too much or too little insulin.

READY MODE

DIAL
2 UNITS

PUSH

Before each use, you Next, pull off inner Hold the pen with the needle facing upwards After priming, the display will
must prime your pen to needle cap and throw and pointing away from your face. Tap the go to READY MODE. You may
check that insulin is away. insulin cartridge holder gently with your need to prime several times
flowing out of the needle finger so that any tiny air bubbles can collect to get a stream of insulin
and to remove air. Turn near the top. Slowly push straight on the coming out of the needle.
dose knob to 2 units. dose knob as shown until dose knob stops. New cartridge setup: A new
When the dose knob stops, continue to hold it cartridge may need to be
in and count to 5 slowly. Priming is primed up to 4 times to get a
complete when a stream of liquid flows from stream of insulin.
the needle tip.
10
☞ Prime every time before injecting. Priming fills any empty spaces inside the needle or cartridge with insulin and checks
that insulin will flow out of your pen when you inject. You may need to prime several times to get a stream of insulin
coming out of the needle. If you do NOT prime, you may get too much or too little insulin.

COMMON QUESTIONS
What should I do if … insulin does not come out when I prime the pen?
The needle may be clogged, the cartridge holder may not be completely screwed on, or the foot of the injection screw may
not be against the cartridge plunger. You may not be able to see the foot of the injection screw, but repeating the priming
step will move it to touch the plunger.
Priming until you see a stream of insulin will ensure that the foot of the injection screw is against the
cartridge plunger as shown here. Cartridge Foot Injection
Plunger Screw
1. Repeat the priming steps until a stream of insulin is seen, see Step 8.
2. If you do not see a stream of insulin after several attempts, attach a new needle.
3. Repeat the priming steps until a stream of insulin is seen.
4. If you are still unable to get insulin flowing out of the needle, do NOT use the pen.
Contact Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare professional.
What should I do if … there is an air bubble in the cartridge after I prime?
Hold the pen with the needle facing upwards and pointing away from your face. Tap the insulin cartridge holder gently with
your finger so any air bubbles can collect near the top. Repeat the priming step. A small air bubble may remain in the
cartridge after the completion of the priming step. If you have properly primed the pen, this small air bubble will not affect
your insulin dose.

11
 SETTING AND INJECTING YOUR INSULIN DOSE
9 Dial Your Dose
Sample Turn the dose knob to your
dose of
22 units
desired dose, which appears
shown. in the display window. If you
dial too many units, you can
correct the dose by dialing
backwards without wasting
insulin.
11 Inject and Confirm Your Dose
Place thumb directly on
the dose knob as shown.
Slowly push straight on dose
knob until dose knob stops.
When the dose knob stops,
continue to hold it in and count
to 5 slowly.
☞ Do NOT attempt to inject your insulin by turning the dose knob. You will NOT receive your insulin by turning the
dose knob. You must PUSH the dose knob straight in for the dose to be delivered.
12
10 Insert Needle
Insert needle. Use
the injection
technique
recommended by
your healthcare
professional.
Remove needle from skin. After injection, pen should
be in READY MODE.
Note: If the display does not show the READY
MODE, the number in the display is the amount
you did NOT receive. Do NOT continue to push
dose knob. To get the rest of your dose, go to
Finishing an Incomplete Dose on page 15.
☞ Do NOT attempt to change the dose while injecting.
☞ Do NOT push the dose knob unless a needle is attached to the pen because this could jam the pen. Removing the
cartridge holder will allow you to release the jam. Then continue from Step 2.
☞ HumaPen MEMOIR has a post-injection timer. There is a 5-second duration from the end of injection (0 showing in the
display) to when it goes back to READY MODE. To use this timer, remove the needle from your skin when the display
returns to READY MODE.

COMMON QUESTIONS
What should I do if … insulin comes out when I dial backwards?
The dose knob may have been accidentally pushed when dialing backwards. To avoid this, do NOT push the dose knob when
dialing backwards. Only push the dose knob when injecting.
What should I do if … the dose knob does not go to 0 when I inject my dose?
Your cartridge may not have had enough insulin for your entire dose. The number in the display window is the amount you
did NOT receive. To get the rest of your dose: Dial down to 0. This will save the first injection in dose memory and return pen
to READY MODE. Next, change the insulin cartridge, see Changing Insulin Cartridge section, and perform Steps 3 to 13
injecting only the dose amount that you did not receive.
What should I do if … it is difficult to push down the dose knob when I try to inject?
a) Pressing the dose knob down quickly may make the button harder to push. Pressing the dose knob more slowly may
make it easier.
b) Pressing on the side of the dose knob may make it harder to inject. Be sure to press straight in on the dose knob as
shown in Step 11.
c) The force required to push the dose knob depends on the needle diameter. See your healthcare professional to determine
which needle diameter is best for you.
d) The dose knob may become harder to push if foreign material (dirt, dust), insulin, or other liquids get inside the pen.
Replace the pen if the dose knob gets too hard to push.

13
 SETTING AND INJECTING YOUR INSULIN DOSE

12 Remove Needle 13 Push Cap On

PUSH
3
1 2

Carefully replace the outer Unscrew the capped Push cap on pen. Pen will
needle cap as instructed by needle, pull off and throw automatically turn off after
your healthcare away as directed by your 30 seconds of inactivity.
professional. healthcare professional.

☞ Remove the needle after completing each injection. Do NOT store the pen with the needle attached.
☞ Directions regarding needle handling are not intended to replace local, healthcare professional or institutional policies.

COMMON QUESTIONS
What should I do if … I want to turn my pen off?
To prevent your pen from accidentally being turned off during an injection, there is no OFF button. Your pen will not
turn off unless the display is in READY MODE. The pen will automatically turn off after 30 seconds of inactivity.

14
 CHANGING INSULIN CARTRIDGE

Remove needle when your insulin Slide empty insulin cartridge out by tilting
cartridge is empty. Unscrew cartridge holder. To insert new cartridge,
cartridge holder and remove it go to Step 3.
from pen body.

FINISHING AN INCOMPLETE DOSE

HumaPen MEMOIR allows you to dial your full dose amount even if there is not enough insulin in the cartridge.
When the injection stops To get the rest of your dose:
and after you have
• Change insulin cartridge (page 15)
released the dose knob,
you will see a number in READY MODE • Inspect insulin and prime
the display. Remember Dial dose knob down to 0. This will save the first (page 6 to page 12)
this number. This is the injection in dose memory and return pen to READY • Dial remaining dose
amount of insulin you MODE. (page 12)
did NOT receive.
Note: It is important to DIAL the dose knob down • Inject and confirm dose (page 12)
to 0. Do NOT PUSH the dose knob in, because Note: Your dose memory will record this
pushing will store a dose in the memory that you as a separate dose.
did not receive.
15
 VIEWING DOSE MEMORY

HumaPen MEMOIR has a dose memory that allows you to see the time, date and amount of the last 16 doses that were
delivered including the priming doses. To see stored doses:

After ‘End’ is displayed, press dose

READY MODE
Press and release dose
Make sure pen is knob to go into dose
in READY MODE. memory. You will see your
most recent dose first.
knob again to go to READY MODE.
Press dose knob Note: If dose knob is not pressed,
repeatedly to see pen will return to READY MODE
all stored doses after 15 seconds. Your HumaPen
until ‘End’ is MEMOIR is tested at the factory
displayed. and may contain several stored
doses when you first receive it.

☞ Since the dose memory saves the date and time of an injection, it is important to keep the pen set to the correct date
and time.
☞ Because the dose memory cannot identify insulin types, it is recommended that a single pen be used with a single
insulin type.

16
 DISPLAY MESSAGES AND ERRORS

DISPLAY WHAT IT MEANS WHAT TO DO

ERRORS
Dose knob dialed past • Dial dose knob backwards until 60 shows in display. Do
60 units NOT dial dose knob past 60.

TO Permanent error has • Do NOT use pen. Contact Lilly at 1-800-LillyRx

happened (1-800-545-5979) or your healthcare professional.

(Always Permanent error has • If the display is always showing 5 units when dialing up or
shows) happened down do NOT use the pen. Contact Lilly at 1-800-LillyRx
(1-800-545-5979) or your healthcare professional.

BATTERY
(Battery Battery is low with • Contact your healthcare professional to get a prescription
flashes)
less than 3 weeks of for a new HumaPen MEMOIR.
life left • Pen can be used until the dead battery symbol shows in
display.

Dead battery • Do NOT use pen. HumaPen MEMOIR is designed to

be used for 3 years. For your safety the batteries are
non-replaceable. Contact your healthcare professional
to get a prescription for a new HumaPen MEMOIR.

17
 DISPLAY MESSAGES AND ERRORS

DISPLAY WHAT IT MEANS WHAT TO DO

PEN OPERATION

2 SECONDS Display check. • No action needed.

Confirms all display • If any part is missing during 2-second display, or if any
1 SECOND parts are working part is lit during 1-second blank display, do NOT use pen.
when pen is turned on. Contact Lilly at 1-800-LillyRx (1-800-545-5979) or your
READY healthcare professional.
MODE

(Colon Pen is in READY MODE • No action needed.

flashes) (Time, date and 0 in display)

Dose has been dialed • No action needed.

End of injection • No action needed.

(Display Reset mode • Dial dose knob back down to 0 and then press and hold dose
flashes) knob for one second. Pen will reset and go to READY MODE.
OR • If pen will not reset, do NOT use pen. Contact Lilly at
(Display 1-800-LillyRx (1-800-545-5979) or your healthcare
does NOT professional.
flash)

18
 DISPLAY MESSAGES AND ERRORS

DISPLAY WHAT IT MEANS WHAT TO DO

DOSE MEMORY
No stored doses in • No action needed.
dose memory yet

(Colon does Dose memory display • No action needed.

NOT flash) (Time, date and number • Display will return to READY MODE after
other than 0 in display) 15 seconds of inactivity.

At the end of stored • Press dose knob to go to READY MODE.

doses • Display will return to READY MODE after
15 seconds of inactivity.

Dose was not stored • You may have injected your last dose too quickly.
(invalid memory) • If your dose memory continues to show several
invalid memories, do NOT use pen. Contact Lilly at
1-800-LillyRx (1-800-545-5979) or your healthcare
professional.

19
 DISPLAY MESSAGES AND ERRORS

DISPLAY WHAT IT MEANS WHAT TO DO

TIME AND DATE
In time setting mode • Press and release dose knob to set time.
• Press ON button to go to next setting.

In time format setting • Press and release dose knob to switch between
mode 12-hour (am/pm) clock and 24-hour clock.
• Press ON button to go to next setting.

(Year In date setting mode • Press and release dose knob to set date.
flashes)
• Press ON button to go to next setting.

In date format setting • Press and release dose knob to switch between
mode day-month (31.12) and month-day (12-31).
• Press ON button to go to next setting.

20
 CARE, STORAGE AND DISPOSAL

• Keep the pen away from dust, extreme hot or cold (freezing) temperatures and direct sunlight.
• Do NOT store the pen in the refrigerator.
• For your insulin cartridge, refer to Information for the Patient for complete storage instructions.
• Keep the pen and case away from water, moisture or wet surfaces as pen and case are not watertight.
• Your injection button may become harder to push if the inside of your pen gets dirty with insulin, food,
drink or other materials.
• Wipe the pen cap, pen body and case with a water-dampened cloth to clean it. Do NOT use alcohol on
the pen body or display window.
• Do NOT use bleach for cleaning or wiping your pen.
• Do NOT use oil or other lubrication on any pen parts.
• Do NOT cover the pen in liquid.
• Follow local regulations for disposal of used pen needles.
• Follow local regulations for disposal of the pen (pen contains lithium batteries).
• For your safety you cannot replace the pen batteries.

If you have any questions or problems with your HumaPen MEMOIR, contact Lilly at
1-800-LillyRx (1-800-545-5979) or your healthcare professional for assistance.

21
 CONTENTS Page
IMPORTANT NOTES 1

SETTING TIME AND DATE 2

User Manual LOADING A CARTRIDGE 4

PREPARING AND PRIMING YOUR PEN 6

INSULIN DELIVERY DEVICE
SETTING AND INJECTING YOUR INSULIN DOSE 12

For use only with Humalog® (insulin lispro injection [rDNA origin]) CHANGING INSULIN CARTRIDGE 15
3 mL Insulin Cartridges (100 IU/mL)
Your HumaPen ® MEMOIR TM may be a different color from the model shown, but it will work the same way. FINISHING AN INCOMPLETE DOSE 15
The HumaPen MEMOIR is designed for ease of use. You can inject from 1 to 60 units of any Humalog (insulin lispro
injection [rDNA origin]) insulin from a 3 mL cartridge (100 IU/mL). You can dial your dose one unit at a time. If you VIEWING DOSE MEMORY 16
dial too many units, you can correct the dose without wasting any insulin. HumaPen MEMOIR has a dose memory
that allows you to see the time, date and amount of the last 16 doses that were delivered including the priming
doses. DISPLAY MESSAGES AND ERRORS 17

CARE, STORAGE AND DISPOSAL 21

Read this entire manual completely and follow the directions carefully before using your new HumaPen MEMOIR. Failure to
follow the instructions may result in too much or too little insulin being delivered. If any of the parts of your HumaPen MEMOIR appear
broken or damaged, do NOT use. Contact Lilly at 1-800-LillyRx (1-800-545-5979) or your healthcare professional for assistance.
Fold out to see PEN PARTS diagram

R x only
PV 5381 AMP
Literature revised November 20, 2006