Transient ischemic attacks are caused by a temporary obstruction in a blood vessel leading to the brain, disrupting cerebral blood flow below critical levels and preventing neurons from maintaining aerobic respiration. Without sufficient oxygen and glucose, neurons switch to anaerobic respiration causing energy failure, acidosis, ion imbalance and increased glutamate and calcium, breaking down cell membranes, proteins and forming free radicals that can cause irreversible cell injury and death if blood flow is not restored quickly. Symptoms include numbness or weakness on one side of the body and impaired sensory perception.
Transient ischemic attacks are caused by a temporary obstruction in a blood vessel leading to the brain, disrupting cerebral blood flow below critical levels and preventing neurons from maintaining aerobic respiration. Without sufficient oxygen and glucose, neurons switch to anaerobic respiration causing energy failure, acidosis, ion imbalance and increased glutamate and calcium, breaking down cell membranes, proteins and forming free radicals that can cause irreversible cell injury and death if blood flow is not restored quickly. Symptoms include numbness or weakness on one side of the body and impaired sensory perception.
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Transient ischemic attacks are caused by a temporary obstruction in a blood vessel leading to the brain, disrupting cerebral blood flow below critical levels and preventing neurons from maintaining aerobic respiration. Without sufficient oxygen and glucose, neurons switch to anaerobic respiration causing energy failure, acidosis, ion imbalance and increased glutamate and calcium, breaking down cell membranes, proteins and forming free radicals that can cause irreversible cell injury and death if blood flow is not restored quickly. Symptoms include numbness or weakness on one side of the body and impaired sensory perception.
Copyright:
Attribution Non-Commercial (BY-NC)
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Download as DOC, PDF, TXT or read online from Scribd
Mitochondria switches to Anaerobic respiration low ATP (energy failure) acidosis ion imbalance inc glutamate depolarization intracellular calcium increased cell membranes and proteins break down formation of free radicals cell injury and death *the death of a neuron is irreversible and nonregenerative Manifestations: Numbness and weakness of face, arm, leg (left side numbness) Sudden severe headache Impaired sensory perception (tactile)