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Factors Affecting Burn Contracture Outcome in Developing Countries
Factors Affecting Burn Contracture Outcome in Developing Countries
290 www.annalsplasticsurgery.com Annals of Plastic Surgery • Volume 77, Number 3, September 2016
METHODS
TABLE 1. Patient Demographics
A retrospective review was performed using the database of
Hand Knee/Elbow one of the programs of the NGO ReSurge International [ReSurge In-
Age, y 0–79 0–65 ternational (formerly Interplast) is a nongovernment organization
Median age, y 10 10 that provides reconstructive surgical care in developing countries
<18 years old 79% 76% for children and adults who lack access. Resurge works in 15 coun-
tries with 12 permanent surgical outreach programs in 8 of them, in-
Median time interval between burn and surgery, y 6 4
cluding Nepal, India, and Zambia]. This program provides a capitated
Cause of burn global fee to the surgeon for burn contracture release. This included
Open fire 77% data on 2506 patients from January 2004 to July 2012 who underwent
Hot liquid 17% burn contracture release surgery for the hand (ie, digits and wrist)
Other 6% (n = 1959), knee (n = 176), and elbow (n = 371) in Nepal, Zambia,
and India. Snake bites resulting in tissue necrosis similar to that seen
with burn injuries were included in the database and in this study.
and advanced follow-up care, contractures may still develop—up to Contracture release in our study includes a broad range of surgical
38.7% of elbow, knee, or shoulder37 burns and up to 44% of hand38,39 techniques implemented for excisional debridement or rearrange-
involvement still result in contracture. ment of scar tissue after burns; most releases were performed by
Secondary burn reconstruction consists of scar contracture release scar excision with skin grafting and/or local tissue rearrangement
performed by tissue rearrangement, skin grafting, or local/regional flaps. (ie, Z-plasty/W-plasty). Demographic information collected in-
With the exception of complex reconstruction with free flaps, secondary cluded location of injury, patients' country of habitation, patient
reconstructive procedures are similar in developing and developed age, time interval between the burn incident and contracture re-
countries. Burn contractures of the hand resulting in syndactyly or lease surgery, and cause of the burn (Table 1). Preoperative and
involving web space are treated with excision followed by local flaps postoperative images of the affected joint were included in the da-
or skin grafting, whereas more extensive deformities may require ex- tabase and were used to generate a score for severity of dysfunction
tensive skin excision, coverage by full-thickness skin grafts, and of- (SOD) and functionality for each patient. Photographs have been
ten tendon repair/transfer.40 Those limited to the digits may be found to be an effective method for grading burns53 and are used
resolved by Z-plasty alone.41 Elbow and knee contractures may be by many burn therapists.54
treated with either Z-plasty or excision plus skin grafting; however, Patient age ranged from younger than 1 to 79 years. Seventy-
deeper burns often require local or regional flaps after excision for nine percent of hand contracture and 76% of knee/elbow contracture
coverage of exposed bone/tendon.28,42 patients were younger than 18 years. Median time waited between burn
Burn victims experience both physical and psychological ef- injury and contracture release surgery was 4 years for knee and elbow
fects from their injuries. Loss of tactile sensation,43 pain, and in- joints, and 6 years for hand and wrist joints. Types of burn included
creased cardiac output44 increase the risk of subsequent injury and in the study were open fire (79% of hand, 71% of knee and elbow),
comorbidity. Loss of limb function—particularly as a consequence hot liquid (14% of hand, 29% of knee and elbow), chemical burn
of contracture formation—results in decreased contribution to soci- (0.2% of hand), acid (5.2% of hand), and snake bite (1.2% of hand).
ety. Burn scars can result in higher rates of unemployment,45 de- Severity of dysfunction of the hand in preoperative and post-
creased opportunity for education,20 low self-esteem,46 episodes of operative images was graded on a scale of 1 to 5, with 5 being the
aggression,47 and mental disorders,48,49 contributing to difficulties inte- most severe, based on the number of digits involved in the burn con-
grating into a community50 and overall decreased quality of life.51,52 tracture, and participation of the wrist in the injury. Grading spe-
These types of outcomes are especially prevalent in low-income cifics are outlined in Figure 1.
countries where few people receive adequate acute care, resulting Functionality of the hand, which we define as joint extension ca-
in disability rates 12.5 times higher than in high-income countries.1 pability of the digits and wrist, was assessed using postoperative images
Contracture release surgery can be invaluable in relieving the socio- then graded on a scale of 1 to 5, 5 being the most functional (Fig. 2).
economic burden of burn-related injuries by improving disability Degree of movement attainable by extension of the fingers was also
and, therefore, quality of life. Elucidating factors that improve out- factored into the grading system. Grade 1 represented a nonfunctional
comes of burn contractures after release surgery will enable burn hand, with only 1 digit capable of extension. Grade 3 represented a hand
surgeons and international organizations to provide better care to with pincer capability. Grade 5 represented a fully functional hand (5 fin-
burn victims, particularly in developing countries where there is gers with full extension capability) and complete wrist extension.
greater demand for such changes. The purpose of this study was to Improvement from surgical intervention for the elbow and
investigate the influence of patient age, time elapsed between the ini- knee was calculated using the difference between preoperative and
tial burn and subsequent surgery, and the type of the burn sustained postoperative angle of maximum extension of the joints. A score
on the outcome of burn contracture release surgery. ranging from 1 to 5 for degree of improvement was assigned to each
FIGURE 1. Scale of burn contractures of the hand: preoperative and postoperative SOD.
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TABLE 2. Factors Affecting Improvement in SOD of the Hand After Surgery Stratified by the Preoperative SOD
292 www.annalsplasticsurgery.com © 2016 Wolters Kluwer Health, Inc. All rights reserved.
TABLE 3. Factors Affecting Postoperative Degree of Functionality of the Hand Stratified by Preoperative SOD
decreased by 0.36 degrees ± 0.13 (P < 0.01). Degree of improvement stratify outcomes to maximize patient improvement, and therefore
was most negatively affected by open fire (−0.36 ± 0.12, P < 0.01), societal benefit, in resource-limited countries. From our data, we
and by patient age (−0.008 ± 0.0052, P < 0.01). created an algorithm and scoring system (BAT score, for Burn type,
Age, and Time interval between burn injury and release) for burn
The Knee contracture patients that can be used to identify patients who are
Open fire burns to the knee fared significantly worse than most likely to experience a favorable outcome from surgical inter-
those sustained with hot liquid (Table 5). After adjusting for the vention. This is similar to current renal transplant priority that strat-
other 2 variables, time interval between the burn and surgery signif- ifies patients not based on severity of disease, but rather by HLA
icantly impacted patient outcome for each additional year elapsed match and proximity to organ procurement site, both of which con-
until surgery, postoperative change in extension decreased by 1.25 de- fer greater potential for transplant success.56 Moreover, we recog-
grees ± 0.35 (P < 0.01). Age also proved to be a factor significantly nize that many burn injuries may not require the specific skillset of
impairing degree of improvement of the knee (−0.015 ± 0.005, P < 0.01). a plastic surgeon; many of these contracture releases can be performed
by appropriately trained general surgeons, thus reserving cases requir-
ing a specialized surgeon for the limited plastic surgeons available.
DISCUSSION Stratification of patients is based on factors affecting contracture out-
More than three quarters of burn contracture release patients come objectively identified in our study—type of burn, patient age,
in this program are younger than 18 years, consistent with the and time elapsed since the burn injury—as well as preoperative SOD.
literature.13–20 Additionally, this age group is faced with lifelong dis- Our data showed greatest improvement in SOD and functionality
ability, which means functional impairment for a larger proportion of after surgery in hands burned by hot liquids. Seventy-three percent of
years lived than people who are older at the time of injury. Our data patients burned by hot liquid had full functionality restored by surgery,
as well as others55 indicate that children have the best outcomes after compared to only 6% of those burned by open fire. More than 85% of
contracture release. These combined elements suggest that young peo- patients with contractures from snake bites, chemical, or acid burns had
ple have the most to benefit from contracture release surgery. no finger or wrist involvement after surgery (grade <1). Further, postop-
Ideally, every person with a contracture as a result of previous erative pincer grasp was restored in every patient who experienced
burn injury would have access to surgical intervention; unfortu- chemical or acid burn, whereas up to 6% of open fire burns and snake
nately, this is not the case, particularly in developing countries where bites gained no pincer ability from surgery. The algorithm shown in
access to reconstructive surgery is limited. Instead, we support a Figure 3 can help health care providers triage burn contracture patients
model in which overall return of functionality and long-term produc- to optimize outcome and use limited resources efficiently.
tivity of the patient is analogous to societal benefit. We aimed to Further studies are needed to validate our evidence-based pro-
identify the factors affecting contractures and their management to posed algorithm and BAT score, applying it to a similar population of
TABLE 4. Elbow Joints: Factors Affecting Extension and Degree of Improvement After Surgery
© 2016 Wolters Kluwer Health, Inc. All rights reserved. www.annalsplasticsurgery.com 293
TABLE 5. Knee Joints: Factors Affecting Change of Angle and Degree of Improvement After Surgery
patients, analyzing the outcomes, and comparing them to those in this initial phases of healing.58 Perceived cost is another common reason
study. The algorithm and BAT scoring system would be validated if for patients to delay care.57 In many low-income countries, primary care
we observe statistically significant improvement in SOD and function- physicians are the first-line medical personnel treating burn-related in-
ality after surgery in the new population of patients. juries, therefore they require training in initial care and follow-up for
Prompt surgical intervention after contracture development (ie, burns.26 Considering the high incidence of burns in developing coun-
at an earlier stage of scar formation) is necessary to maximize potential tries and the subsequent detrimental impact they have on finding/
future functionality. However, prolonged time interval waited (in our maintaining employment,45 providing surgical intervention in the time-
study, a median of 4 and 6 years for elbow/knee and hand, respectively) liest manner possible after burn injury may profoundly decrease mor-
suggests poor access to surgical care for burn injuries. Another study bidity and improve quality of life globally.
found a similar delay of 2.8 years before receiving contracture release Improvement in SOD was observed in 98% of patients in this
surgery.57 Lack of plastic surgeons in certain geographical locations is study after contracture release surgery of the hand, knee, or elbow joint.
a leading cause of failure to receive appropriate care during critical Burn contractures of the hand are especially debilitating due to the
FIGURE 3. Algorithm for stratification of burn contracture patients for surgical intervention and BAT scoring system.
294 www.annalsplasticsurgery.com © 2016 Wolters Kluwer Health, Inc. All rights reserved.
involvement of the hand in activities of daily living (ADLs) such as 11. Giashuddin SM, Rahman A, Rahman F, et al. Socioeconomic inequality in child
bathing and grooming38; pincer grasp, and therefore thumb function, injury in Bangladesh—implication for developing countries. Int J Equity Health.
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this joint can cause 57% loss of entire body function.60 The elbow only
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individual surgeons and distinct sites. Our study is limited by lack 19. Al-Qattan MM, Al-Tamimi AS. Localized hand burns with or without concurrent
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