Drug Name Mode of Action Indication Contraindication Drug Effects Nursing Considerations

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DRUG NAME MODE OF ACTION INDICATION DRUG EFFECTS NURSING CONSIDERATIONS

CONTRAINDICATION
Generic Name: Binds to bacterial cell wall, Indication: Side Effects:  Assess patient for allergy to
ampicillin resulting to cell death. Treatment of the following  Diarrhea penicillin, cephalosporins, or
Brand Name: infections: Skin and skin  Rashes other allergens; renal
Marcillin, Omnipen, Principen structure infections; Soft-tissue  Hives disorders. Patients with a
Classification: infections; Otitis media, Sinusitis;  Fever negative history of penicillin
Anti-infectives Respiratory infections;  Nausea sensitivity may still have an
Dose: Genitourinary infections; allergic response
2g Meningitis; Septicemia; Adverse Effects:  Assess patient for infection
Frequency: Endocarditis prophylaxis.  Nephrotoxicity (urine, stool, vital signs,
q6h wound appearance, sputum,
 Thrombocytopenia
Route: Contraindication: and WBC) at the beginning
 Neutropenia
IV infusion A history of previous of and throughout therapy.
hypersensitivity reaction to any  Agranulocytosis  Check IV site carefully for
penicillin. Infectious signs of thrombosis or drug
mononucleosis patients develop reaction.
a rash, and therefore use is  Advice patient to report pain
avoided. Renal and hepatic or discomfort at sites,
function should be monitored. unusual bleeding or bruising,
mouth sores, rash, hives,
fever, itching, severe
diarrhea, difficulty breathing.
 Instruct patient to take the
medication around the clock
and finish the drug
completely as directed, even
if feeling better.
DRUG NAME MODE OF ACTION INDICATION DRUG EFFECTS NURSING CONSIDERATIONS
CONTRAINDICATION
Generic Name: Inhibits the enzyme COX-2. This Indication: Side Effects:  Assess patient for allergy to
celecoxib enzyme is required for the Relief of signs and symptoms of  Diarrhea sulfonamides, aspirin, or
Brand Name: synthesis of prostaglandins. Has osteoarthritis, rheumatoid  Hypertension NSAIDs. Patients with these
Celebrex analgesic, anti-inflammatory, and arthritis, ankylosing spondylitis,  Abdominal pain allergies should not receive
Classification: antipyretic properties. and juvenile rheumatoid arthritis.  Flatulence celecoxib.
NSAIDs Reduction of the number of  Vomiting  Instruct patient to take
Dose: adenomatous colorectal polyps  Constipation celecoxib as directed. Do not
200 mg in familial adenomatous take more than prescribed
 Nausea
Frequency: polyposis (FAP), as an adjunct to dose. Increasing doses does
 Dizziness
b.i.d. usual care (endoscopic not appear to increase
Route: surveillance, surgery). effectiveness.
Adverse Effects:
PO Management of acute pain,  Advise patient to notify health
including primary dysmenorrhea.  GI bleeding
care professional promptly if
 Stroke
signs or symptoms of GI
Contraindication:  Myocardial Infarction
toxicity (abdominal pain,
 Hypersensitivity;  Exfoliative dermatitis black stools), skin rash,
 Cross-sensitivity may exist  Toxic-epidermal necrolysis unexplained weight gain, or
with other NSAIDs, including  Stevens-Johnson Syndrome edema occurs.
aspirin;  May cause hypertension.
 History of allergic-type Instruct patient in correct
reactions to sulfonamides; technique for monitoring BP
 History of asthma, urticaria, and to notify health care
or allergic-type reactions to professional if significant
aspirin or other NSAIDs, changes occur.
including the aspirin triad
(asthma, nasal polyps, and
severe hypersensitivity
reactions to aspirin);
 Advanced renal disease;
 Severe hepatic impairment;
 Coronary artery bypass graft
(CABG) surgery

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