University of Southern Mindanao

College of Health Sciences

Department of Nursing

DRUG STUDY
Name of Patient: ___________________________________________________ Age: ______ Sex: _____ Room: ________ Date: ___________________________
Admitting Diagnosis: _______________________________________________ Attending Physician: __________________________Diet: __________________

NAME OF CLASSIFICATIO INDICATIO MECHANISM CONTRAINDICATION SIDE EFFECTS ADVERSE EFFECTS NURSING
DRUG N N OF ACTION RESPONSIBILITIE
S
Brand Therapeutic: Treatment of Although the The following conditions  Dizziness  Worsening of  Watch for
name: Antipsychotics Schizophreni exact are contraindicated with  Drowsiness glaucoma signs of
Mellaril a in patients mechanism of this drug:  Constipation  Increased or neuroleptic
Pharmacologic: who don’t antipsychotics  Low amount of  Dry mouth decreased of blood malignant
Generic Phenothiazines respond to is unknown. magnesium and  Urinary retention glucose syndrome
name: treatment with Scientists potassium in the  Blurred vision  Abnormal muscle including
Thioridazine at least two believe that blood  Low BP contractions hyperthermia,
other atypical they work by  Low level of WBC  Seizures  Difficulty in diaphoresis,
Dosage: antipsychotics blocking the type which is breathing and generalized
 Lightheadedness
50 to 100 action of Neutrophils swallowing muscle rigidity,
 Headache
mg P.O TID; dopamine in the  Parkinsonism  Neck spasms altered mental
 Restlessness
increase brain.  Tardive  Leukopenia status,
gradually to Dopamine is a  Weight gain tachycardia,
dyskinesia
 Tachycardia  Photosensitivity
800 mg daily neurotransmitte  Extrapyramidal changes in BP.
 Ileus  Rashes
in divided r that nerves Symptoms
disease
 Priapism  Anorexia
doses as use to  Neuroleptic typically occur
needed. communicate  hyperthermia  Allergic reactions
malignant within 4-14
Daily with one  Agranulocytosis days after
syndrome
maintenanc another.  Torsades de initiation of
e doses Thioridazine is pointes drug therapy
range from used when but can occur
 Pregnancy
200 to 800 patients do not anytime during
 Slow heartbeat
mg divided respond to drug use
into two to other  Prolonged QT  Assess heart
four doses antipsychotics interval on EKG rate, ECG, and
 Orthostatic heart sounds
hypotension especially
 Coma during
 Seizures exercise.
 Pregnancy Report
 Dementia in immediately a
elderly rapid heart
 CYP2D6 poor rate, or any
metabolizer other
arrhythmias
 Monitor signs
of
agranulocytosi
s and
leukopenia
including fever,
sore throat,
mucosal
lesions, and
other signs of
infection
 Assess motor
function and
be alert for
extrapyramidal
symptoms
especially
tardive
dyskinesia
 Report
immediately for
signs of
pseudo
parkinsonism
  Report
immediately for
signs of
akathisia
 Report
immediately for
signs of
dystonia’s and
dyskinesias
 Monitor signs of
allergic
reactions
including
pulmonary
symptoms
 Assess BP
periodically and
compare to
normal values.
Report low BP
especially if
patient
experiences
dizziness or
syncope
 Periodically
assess body
weight and other
anthropometric
measures.
Report a rapid
or unexplained
weight gain or
increased body
fat

Bibliography: Ciccone, D. Davi’s Drug Guide for Rehabilitation Professionals. F.A Davis PT Collection. McGraw Hill Medical
Kluwer, W. (2020). Nursing 2020 Drug Handbook
 University of Southern Mindanao
College of Health Sciences
Department of Nursing

DRUG STUDY
Name of Patient: ___________________________________________________ Age: ______ Sex: _____ Room: ________ Date: ___________________________
Admitting Diagnosis: _______________________________________________ Attending Physician: __________________________Diet: __________________

NAME OF CLASSIFICATION INDICATION MECHANISM CONTRAINDICATION SIDE EFFECTS ADVERSE NURSING

DRUG OF ACTION EFFECTS RESPONSIBILITIES
Brand name: Therapeutic: Used to treat Though to The following conditions  Dizziness  Urinary  Instruct the
Stelazine Antipsychotics certain mental exert its are contraindicated with  Drowsiness retention patient that the
disorder/mood antipsychotic this drug:  Constipation  Decreased drug should not
Generic name: Pharmacologic: disorders effects by  Breast cancer  Dry mouth cough reflex be use I he/she
Trifluoperazine Phenothiazines (schizophrenia, postsynaptic  Anemia  Swelling of is intoxicated
 Low BP
psychotic blockade of  Low level of feet and with
Dosage: disorders) it CNS dopamine neutrophils  Seizures ankles alcohol/opioids/o
30 mg P.O helps you to receptors,  Parkinsonism  Lightheadedness  Rashes on ther drug that
daily given in think more inhibiting  Tardive dyskinesia  Headache nose and cause
two or three clearly, feel dopamine-  Extrapyramidal  Restlessness cheeks drowsiness/slow
divided doses. less nervous, mediated disease  Weight gain  Joint pain ed breathing
If no signs of and take part in effects;  Neuroleptic  Tachycardia  Skin  Instruct the
improvement everyday life. It antiemetic patient that this
after a can reduce effects are
malignant  Ileus discoloration
syndrome  Vision drug may make
reasonable aggressiveness attributed to  Trouble in sleeping him dizzy or
 Glaucoma changes
period (up to 2 and the desire dopamine drowsy or blur
 Angina  Signs of liver
weeks) may to hurt yourself receptor his vision
 Orthostatic problems
increase or others. May blockade in the
hypotension  Unusual cold  Instruct the
dosage in also help to medullary patient not to
10mg/day decrease chemoreceptor  Hardening of liver or hot feeling
drive, use
increments at hallucinations, trigger zone caused by alcohol
machinery, or do
intervals of 1 helps to restore  Seizures
anything that
to 3 weeks. the balance of  Enlarged prostate
Maximum total certain natural with urination needs alertness
daily dosage is substances of problem or clear vision
60 mg the brain.  Inability to until he can do it
completely empty safely
the bladder  Instruct to avoid
 pregnancy alcoholic
beverages
 Instruct that this
medication will
make the patient
more sensitive
to the sun. limit
time of exposure
to the sun
 Instruct the
patient that this
medication will
make him sweat
less making him
more likely to
get heat stroke
 When the
weather is hot,
instruct to drink
a lot of fluids
and dress lightly
 Get a medical
help if you have
a fever that does
not go away,
mood changes,
headache,
dizziness
 Monitor HR and
BP, Hypotension
is a common
 adverse effect
 Monitor I&O
ratio and bowel
elimination
pattern. Check
for abnormal
distension and
pain.

Bibliography: Kluwer, W. (2020). Nursing 2020 Drug Handbook,

WebMD LCC. (2021) Stelazine Tablet
 University of Southern Mindanao
College of Health Sciences
Department of Nursing

DRUG STUDY
Name of Patient: ___________________________________________________ Age: ______ Sex: _____ Room: ________ Date: ___________________________
Admitting Diagnosis: _______________________________________________ Attending Physician: __________________________Diet: __________________

NAME OF CLASSIFICATION INDICATION MECHANISM OF CONTRAINDICATION SIDE EFFECTS ADVERSE NURSING

DRUG ACTION EFFECTS RESPONSIBILITIES
Brand name: Therapeutic: Schizophrenia in Unknown. Binds  Diabetes  Monitor patient
Clozaril Antipsychotics severely ill patients selectively to  Excessive fat in with diabetes
unresponsive to dopaminergic the blood regularly.in
Generic name: Pharmacologic: other therapies; to receptors in the  Low amount of patients with
Clozapine Debenzapine reduce risk of CNS and may magnesium and risk factors of
derivatives recurrent suicidal interfere with potassium in the diabetes,
Dosage: behavior in adrenergic, blood obtain fasting
12.5mg P.O once schizophrenia or cholinergic,  Overweight blood glucose
daily or BID. schizoaffective histaminergic, and  Dehydration test results at
Adjust dose disorders serotonergic  Decrease baseline and
upward by 25 to receptors function of bone periodically
50mg daily (if marrow  Monitor patient
tolerated) to 300  Very low level of for metabolic
to 450mg daily by granulocytes syndrome
end of 2 weeks. including
 Close angle
Individual dosage significant
glaucoma
is based of clinical weight gain
 Slow heartbeat
response, patient and increased
tolerance, and  Prolonged QT
BMI, HTN,
adverse reactions interval on EKG
hyperglycemia
 Inflammation of
 Monitor for
middle tissue
signs and
heart muscle
 Sinus symptoms of
tachycardia myocarditis
 Clot in the lungs and
 Low seizure cardiomyopath
threshold y
 Torsades de  Some patients
pointes experience
 Stroke transient fever
 Liver problems with
 Smoking temperature
 Metabolic higher than
syndrome 100.4 degrees
Farenheight.
 Dilated
Monitor closely
cardiomyopathy
 Drug is not
 Dementia in
indicated use
elderly
for elderly
 Construction of
patient with
intestine
dementia-
related
psychoses
because of an
increased risk
for death from
CV disease or
infection
 If patient
reports onset
of fever while
discontinuing
drug, continue
to monitor ANC
for an
additional 2
weeks after
drug is
 discontinued
 When
discontinuing
drug, monitor
patient
carefully for
recurrence of
psychotic
symptoms
related to
cholinergic
rebound
 Drug can cause
sedation and
impair cognitive
and motor
performance.
Monitor patient
carefully for
CNS changes
 Complete fall
risk
assessments
when initiating
therapy and
recurrently for
patients on long
term therapy,
especially
elderly patients
and patients
who are taking
other
medications that
could
exacerbate fall
risk
 Do not confuse
 clozapine with
clonidine,
clofazimine,
clonazepam, or
Klonopin, don’t
confuse Clozaril
with colazal

Bibliography: Kluwer, W. (2020) Nursing 2020 Drug Handbook

 University of Southern Mindanao
College of Health Sciences
Department of Nursing

DRUG STUDY
Name of Patient: ___________________________________________________ Age: ______ Sex: _____ Room: ________ Date: ___________________________
Admitting Diagnosis: _______________________________________________ Attending Physician: __________________________Diet: __________________

NAME OF CLASSIFICATIO INDICATION MECHANIS CONTRAINDICATION SIDE EFFECTS ADVERSE EFFECTS NURSING
DRUG N M OF RESPONSIBILITIE
ACTION S
Brand name: Therapeutic:  Psychosis, It produces its  contraindicated in  Dizziness  Hyperpyrexia  may cause
Thorazine Antipsychotics mania antipsychotic pre-existing CNS  Drowsiness  Peripheral neuroleptic
 nausea, effect by the depression  Anxiety edema malignant
Generic name: Pharmacologic: vomiting post-synaptic  use in caution, or  Insomnia  Systemic lupus syndrome,
Chlorpromazin Phenothiazines  pre-op blockade at not at all with  Breast  Trouble having sedation,
e hydrochloride sedation the D2 impaired liver, swelling orgasm tardive
 Acute receptors in kidney,  Changes in dyskinesia,
Dosage: intermittent the cardiovascular, menstrual hypotension,
50 to 100mg IV porphyria, mesolimbic cerebrovascular period agranulocytosi
daily divided intractable pathway and respiratory  Weight gain s
every 6 hours. hiccups function  Swelling of  assess mental
Increased  Behavioral  use cautiously in hands and feet status prior to
dosage up to hyperthyroidism, and during
disorders,  Dry mouth
100 mg daily hyperactivity acute infections, treatment
 Stuffy nose
may be needed jaundice, and  monitor BP
 Impotence
leucopeni  ensure patient
is taking
medication
 monitor CBC
and liver
function tests
 instruct patient
not to skip
doses or
double the
doses
 apnea
monitoring
whilst on
medication
 observe for
signs of
adverse
effects
 patient should
remain supine
for 30 mins
after IM
injection,
monitor BP
(tachycardia
may occur with
IM injection)
 ocular
examinations,
and EEG are
recommended
before and
periodically
during
prolonged
therapy
Bibliography: Kluwer, W. (2020) Nursing 2020 Drug Handbook
 University of Southern Mindanao
College of Health Sciences
Department of Nursing

DRUG STUDY
Name of Patient: ___________________________________________________ Age: ______ Sex: _____ Room: ________ Date: ___________________________
Admitting Diagnosis: _______________________________________________ Attending Physician: __________________________Diet: __________________

NAME OF CLASSIFICATIO INDICATION MECHANIS CONTRAINDICATION SIDE EFFECTS ADVERSE EFFECTS NURSING
DRUG N M OF RESPONSIBILITIE
ACTION S
Brand name: Therapeutic:  Psychotic A  Contraindicated in  Dry mouth  Severe  Monitor patient
Haldol Antipsychotics disorders butyrophenone patients  Increased saliva extrapyramidal for tardive
 Chronic that probably hypersensitive to  Blurred vision reactions dyskinesia
Generic Pharmacologic: psychosis exerts drug and in those  Loss of appetite  Dystonia which may
Name: Butyrophenone antipsychotic 
requiring with Parkinson  Constipation Tardive dyskinesia occur after
Haloperidol derivatives prolonged effects by disease or CNS  Diarrhea  Seizures prolonged use.
therapy blocking depression  Heartburn  Lethargy It may not
Dosage:
 Nonpsychotic postsynaptic  Use cautiously in  Nausea  Confusion appear until
Initially, 0.5 to
behavior dopamine elderly and  Dyspepsia  Vertigo months or years
5mg P.O BID
disorders receptors in the debilitated patients  later and may
or TID.  Vomiting Agitation
Maximum  Tourette brain  Use cautiously in  Headache  Euphoria disappear
100mg PO syndrome patients at risk for  Restlessness spontaneously
daily or 2 to 5 falls, including or persist for
 Hallucinations
mg lactate IM those with disease life, despite
 Urine retention
every 4 to 8 or conditions or ending drug
 Menstrual
hours, who are taking  Watch for signs
irregularities
although drugs that may and symptoms
hourly  Priapism
cause somnolence, of NMS which is
administratio  Jaundice
orthostatic rare but
 n may be hypotension, or  Hyperglycemia commonly fatal
needed until motor or sensory  Skin reactions  Monitor ECG
control is irritability  Diaphoresis patient when
obtained  Blood dyscrasias  Gynecomastia drug is given in
have been high doses or
reported. when patient is
Discontinue drug taking other QT
for ANC less than interval
1,000/mm or for prolonging
leukopenia or drugs because
agranulocytosis of the increased
 Severe risk of QT
extrapyramidal interval
reactions, prolongation
hypotension, and torsades de
sedation, EEG pointes
abnormalities  Don’t withdraw
drug abruptly
unless required
by severe
adverse
reactions
 Complete fall
risk assessments
at start of
antipsychotic
treatment and
recurrently for
patients on long
-term therapy,
especially those
at increased risk
for falls
 Esophageal
 dysmotility and
aspiration can
occur. Use
cautiously in
patients at risk
for aspiration
(those with
pneumonia
Alzheimer
disease)
 Don’t confuse
Haldol with
Halcion or Halog
Caution patient
or caregiver of
patient taking
an opioid with a
benzodiazepine,
CNS depressant,
or alcohol to
seek immediate
medical
attention for
dizziness
 Advise patient
to report all
adverse
reactions
 Warn patient to
avoid activities
that require
alertness and
good
coordination
 until effects of
drug are known
 Advise patient
that drug may
cause
somnolence,
orthostatic

Bibliography: Kluwer, W. (2020) Nursing 2020 Drug Handbook

Bai Kc Olaizzah A. Mokalid Norabin O. Molina, RN

Student Nurse Clinical Instructor