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1.

Hydrochloric acid
Formula: HCl
GHS Pictogram:
a. Corrosive- Causes severe skin burns, skin corrosion and eye damage.

b. Oral and Respiratory Tract Irritant- May cause oral and respiratory irritation of the when
fumes and mist are inhaled.

Chemical Incompatibility (atleast 2):


a. Acetic anhydride (Weak Organic Acid)- Acetic anhydride reacts with HCl in a violent
exothermic reaction
b. Ammonium hydroxide (Weak Inorganic Base)- HCL (from the acid) and Ammonia (from
the Ammonium hydroxide) react together forming ammonium chloride (the white smoke)
which may be toxic to the environment.
c. Others: Hydrogen peroxide, Sodium hydroxide, Calcium hydroxide, Chloroform, Acetone
Methanol, Nitric Acid, Acetic Acid etc.
Reference: https://www.nwmissouri.edu/naturalsciences/sds/h/Hydrochloric%20acid.pdf
2. Sodium hydroxide
Formula: NaOH
GHS Pictogram:
a. Corrosive- May be corrosive to metals and causes severe skin burns and eye damage

b. Environmentally Damaging (Acute Aquatic Toxicity)- Acute hazards to Aquatic Life

Chemical Incompatibility:
a. Acetic Acid (Weak Organic Acid)
b. Hydroflouric Acid (Weak Inorganic Acid)
c. Oxidizing agents (e.g. peroxides)
d. Metals (e.g. aluminum)
Reference: https://beta-
static.fishersci.com/content/dam/fishersci/en_US/documents/programs/education/regulatory-
documents/sds/chemicals/chemicals-s/S25550.pdf
3. Cupric sulfate
Formula: CuSO4
GHS Pictogram:
a. Environmentally Damaging (Both Acute and Chronic Aquatic Toxicity)- Toxic to Aquatic
Environment with both short and long term effects

b. Acute Oral Toxicity- Toxic if swallowed.

c. Health Hazard (Single Target Organ Toxicity with Single and Repeated Exposure,
Reproductive and Respiratory Hazard, etc.)- Copper sulfate may induce severe gastroenteric
distress (vomiting, gastroenteric pain, and local corrosion and hemorrhages), prostration,
anuria, hematuria, anemia, increase in white blood cells, icterus, coma, respiratory
difficulties, and circulatory failure.

d. Respiratory Tract Irritant-May cause oral and respiratory irritation of the when fumes and
mist are inhaled.
Chemical Incompatibility:
a. Hydroxylamine (Weak Inorganic Base)-Ignition occurs in mixing Cupric Sulfate and
Hydroxylamine
b. Magnesium Hydroxide (Strong Inorganic Acid) -Magnesium will be oxidize rapidly as
there is high water content in Copper sulfate. Then magnesium ions will displace copper ions.

References: https://cameochemicals.noaa.gov/chemical/3025
4. Naphthalene
Formula: C10H8
GHS Pictogram:
a. Flammable solids

b. Acute Oral Toxicity and considered to be Carcinogen

c. Irritant- Can cause Eye Irritation


d. Environmentally Damaging (Both Acute and Chronic Aquatic Toxicity)- Toxic to Aquatic
Environment with both short and long term effects

Chemical Incompatibility (atleast 1):


a. Chromic anhydride
b. Strong Oxidizers like Ammonium perchlorate, Bromine, Chromic acid, Dibenzoyl
peroxide, Hydrogen peroxide, Perchloric acid.
References: https://www.nwmissouri.edu/naturalsciences/sds/n/Naphthalene.pdf
https://www.cdc.gov/niosh/npg/npgd0439.html

5. Methanol
Formula: CH3OH
GHS Pictogram:
a. Flammable liquid

b. Acute Oral Toxicity- Toxic if swallowed.

Chemical Incompatibility (atleast 2):


 Oxidizing Agents like:
a. Hydrogen peroxide
b. Sodium hydroxide
c. Calcium hydroxide
 Acids like:
a. Nitric Acid
b. Chromic Acid
c. Sulfuric Acid
 Others: Acid chlorides, acid anhydrides, oxidizing agents, alkali metals, reducing
agents, acids.
References: https://pubchem.ncbi.nlm.nih.gov/compound/Methanol#section=2D-Structure

6. Baeyer's reagent
Formula: KMnO₄
GHS Pictogram:
a. Flammable- May intensify fire, oxidizers

b. Irritant- Skin irritation

c. Environmentally Damaging (Both Acute and Chronic Aquatic Toxicity)- Toxic to Aquatic
Environment with both short and long term effects

Chemical Incompatibility:
a. Glycerol
b. Ethylene glycol
c. Benzaldehyde
d. Sulfuric acid
References: https://ehs.utk.edu/wp-content/uploads/2017/06/Incompatible-Chemicals-
List.pdf

7. Bleach
Formula: NaClO
GHS Pictogram:
a. Corrosive- May be corrosive to metals and causes severe skin burns and eye damage

b. Irritant- Skin irritation, Acute Toxicity (Oral)

c. Environmentally Damaging (Both Acute and Chronic Aquatic Toxicity)- Toxic to Aquatic
Environment with both short and long term effects

Chemical Incompatibility (atleast 2):


a. Hydrochloric Acid
b. Sulfuric Acid
c. Phosphoric Acid
d. Aluminum Chloride
e. Ferrous and Ferric Chloride
f. Ferrous and Ferric Sulfate
g. All Organic and Inorganic Acids and All Other Acids, Metals
h. Iodides, Sodium Borohydride, Sodium Bisulfite, Sodium Hydrosulfate, Sodium Sulfate
Sodium Thiosulfat and All other Reducing Agents
Reference: https://www.amherst.edu/system/files/media/Bleach%2520Incompatibility.pdf
https://beta-
static.fishersci.com/content/dam/fishersci/en_US/documents/programs/education/regulatory-
documents/sds/chemicals/chemicals-s/S25552.pdf
8. Diethyl ether
Formula: (C2H5)2O
GHS Pictogram:
a.Flammable- Extremely flammable liquid and vapor [Danger Flammable liquids]

b. Irritant- Causes eye irritation [Warning Serious eye damage/eye irritation]May cause
drowsiness or dizziness [Warning Specific target organ toxicity, single exposure; Narcotic
effects]

c. Environmentally Damaging (Acute Aquatic Toxicity)- Very toxic to aquatic life [Warning
Hazardous to the aquatic environment, acute hazard], Toxic to aquatic life with long lasting
effects [Hazardous to the aquatic environment, long-term hazard]

d. Health Hazard-May cause respiratory irritation [Warning Specific target organ toxicity,
single exposure; Respiratory tract irritation], Harmful if swallowed [Warning Acute toxicity,
oral] ,Suspected of damaging fertility or the unborn child [Warning Reproductive toxicity],
Causes damage to organs through prolonged or repeated exposure [Danger Specific target
organ toxicity, repeated exposure]

Chemical Incompatibility (atleast 2):


 Violent reaction or ignition on contact with: Boron triazide, bromine trifluoride,
bromine pentafluoride, bromine, iodine heptafluoride, Silver perchlorate, Fluorine
nitrate, Permanganic acid, Nitric acid, Hydrogen peroxide, Peroxodisulfuric acid,
iodine(VII) oxide, Thiotriazyl perchlorate, Sulfonyl chloride, Sulfur, Chlorine, Uranyl
Nitrate. Strong oxidizers, Halogens, Sulfur, Sulfur Compounds [Note: Tends to form
explosive peroxides under influence of air and light.]
References: https://webwiser.nlm.nih.gov/substance?substanceId=11&identifier=Diethyl
%20Ether&identifierType=name&menuItemId=184&catId=242
https://webwiser.nlm.nih.gov/substance?substanceId=11&identifier=Diethyl
%20Ether&identifierType=name&menuItemId=7&catId=64

9. Tollen's reagent
Formula: Ag(NH3)2OH
GHS Pictogram:
a. Environmentally Damaging (Acute Aquatic Toxicity)- Very toxic to aquatic life [Warning
Hazardous to the aquatic environment, acute hazard], Toxic to aquatic life with long lasting
effects [Hazardous to the aquatic environment, long-term hazard]

b. Health Hazard-Carcinogenicity, Specific target organ toxicity (repeated exposure)-May


cause damage to hematopoietic system, kidneys, liver, and/or stomach through prolonged
and repeated exposure if swallowed.

a. Corrosive- Corrosive to metals and causes severe skin burns and eye damage.

Chemical Incompatibility:
 Strong acids like Hydrochloric acid, Hydrobromic Acid etc. Strong oxidizers like
halogens that are good oxidizing agents include iodine, bromine, chlorine, and
fluorine. Ammonium perchlorate, Bromine, Chromic acid, Dibenzoyl peroxide,
Hydrogen peroxide

References: https://beta-
static.fishersci.com/content/dam/fishersci/en_US/documents/programs/education/regulator
y-documents/sds/chemicals/chemicals-f/S25313.pdf
10. Sulfuric acid
Formula: H₂SO₄
GHS Pictogram:
a. Corrosive- May be corrosive to metals and causes severe skin burns and eye damage;
Corrosive to metals

b. Environmentally Damaging (Both Acute and Chronic Aquatic Toxicity)- Toxic to Aquatic
Environment with both short and long term effects

c. Acute Oral Toxicity

Chemical Incompatibility:
 Potassium chlorate, Potassium perchlorate, Potassium permanganate, (similar
compounds of light metals, such as sodium, lithium)
References: http://www.labchem.com/tools/msds/msds/LC25550.pdf

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