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Surgical Group - Normal Physiologic Changes in Aging Affecting Various Systems
Surgical Group - Normal Physiologic Changes in Aging Affecting Various Systems
Submitted by:
Dalagan, Maria Rafaela Julliana Q.
Danseco, Danna Francesca S.
del Rosario, Carylle M.
Escojedo, Dennise Ann H.
Eslit, Lynn Chantal
Famacion, Kyra Bianca R.
Hallazgo, Rex G.
Jardiolin, Roland Laurence B.
Kho, John Carlo
Lagbas, Raphaella
Macaibay, Erika France
BSN 3 - NA
Submitted to:
September 2, 2021
Normal Physiologic Changes in Aging Affecting Various Systems
Gastrointestinal ● Mouth
○ Affect ability to chew
○ Age-related changes in teeth cause them to
be less sensitive and more brittle
○ Atrophy of those muscles and bones of the
jaw and mouth that control mastication
○ Although almost 40% of older adults
complain of dry mouth, salivary gland
function remains stable with age due to the
large secretory reserve in the main salivary
glands
○ Dry mouth can be attributed to prescription
and over-the-counter medications,
nutritional deficiencies, disease, and
treatment therapies such as chemotherapy
● Esophagus
○ Impaired esophageal motility function in
older individuals led to the development of
the term presbyesophagus
○ Aging until around age 80, when some
changes occur such as decline in upper
esophageal sphincter pressure, increased
time for the upper esophageal sphincter to
relax, and decreased intensity of
esophageal contractions, potentially caused
by loss of muscle abilities and nerve
innervations
○ Stiffening of the esophageal wall and less
sensitivity to discomfort and pain in the
esophagus affecting the older patient’s
ability to swallow
○ The gag reflex also appears to be absent in
around 40% of healthy older adults
○ Dysphagia (difficulty swallowing), reflux,
heartburn, and chest pain are common
complaints that relate to changes in the
pharynx and esophagus
○ Duration of gastroesophageal episodes
appears to be more prolonged
● Stomach
○ Peristalsis and gastric contractile force are
mildly reduced in the elderly and that the
reduction reaches significance in less active
elderly subjects rather than in those who
maintain an active lifestyle
○ Pepsin, bicarbonate, and sodium ion
secretions and prostaglandin content show
age-related decline causing a decline in
gastric defense mechanisms and create an
increased potential for mucosal injury in the
stomach
● Small Intestine
○ Decrease in gastric acid secretion in
approximately 32% of elderly people
○ This decreased acid production along with
motility disturbances in the small intestine
can lead to bacterial overgrowth in the
small intestine, a common clinical finding in
the older population, causing malabsorption
and malnutrition
● Large Intestine
○ Older adults experience longer colonic
transit time (the amount of time needed for
fluid and excrement to travel the length of
the colon). This change again relates to
age-related loss of neurons and receptors
in the enteric nervous system. Increased
colonic transit time also correlates with
increased fibrosis in the colon.
○ Colonic pressure in the intra-lumen also
increases with age, but can be lowered with
fiber supplementation.
○ The rectum shows an age-related increase
in fibrous tissue. This increase reduces the
rectum’s ability to stretch as feces pass
through
○ In the anus, the external anal sphincter
shows an age-related decrease in motor
neurons responsible for sphincter control.
○ This sphincter also thins with age
○ The internal anal sphincter thickens with
age, possibly as a compensatory
mechanism. It shows a decline in
contractile abilities.
○ Aging women experience a greater risk of
anal sphincter changes due to laxity of the
pelvic floor, decreased pressure in the
rectum, and even menopause.
● Liver
○ The liver’s size as well as its blood flow and
perfusion can decrease by 30% to 40%. In
addition, hepatocytes, or liver cells, can
undergo structural alterations. However,
due to the liver’s large reserve capacity and
the hepatocytes’ ability to regenerate after
damage, no functional changes result from
the changes in structure
○ Decreased drug clearance due to the
declines in liver size and blood flow as well
as age-related changes in the kidneys
● Gallbladder
○ Appears to demonstrate declines in
emptying rates so that less bile is secreted
when food is digested
○ Increased bile volume in the gallbladder
has been correlated with gallstones in older
adults. This increase in bile volume is more
common in older women than men.
○ The bile ducts tend to widen with age,
allowing potential gallstones to pass
through more easily; however, the duct near
the opening of the small intestine becomes
narrower, trapping the gallstones and
leading to abnormal changes.
● Pancreas
○ Decreases in weight with age and shows
some histological changes such as fibrosis
and cell atrophy.
● Immunity
○ Decline in immunological function in the
aging gastrointestinal system. This decline
can increase rates of infections that occur
via the gastrointestinal system. Infection
may, in turn, lead to mortality and morbidity.
○ A decline in gastrointestinal immunity can
be attributed to a change in lymphoid cells
or epithelial cells, or possibly both cell
types.
○ Changes that occur increase the risk for
diseases and disorders.
○ Age-related changes, compounded by other
influential factors such as comorbidity and
medication use, place older individuals at
increased risk for gallstones, constipation,
fecal incontinence, and infection.
Sensory
Mauk, K. L. (2010). Gerontological Nursing: Competencies for Care (2nd ed.). Jones &
(0000)Bartlett Learning.
Mauk, K. L. (2017). Gerontological Nursing: Competencies for Care (4th ed.). Jones &
(0000)Bartlett Learning.
Aging changes in the senses. (n.d.). MedlinePlus. Retrieved September 2, 2021, from
https://medlineplus.gov/ency/article/004013.htm