LAST​ ​MINUTE​ ​REVISION​ ​POINTS​ ​(LMRP)​ ​for​ ​SURE​ ​SUCCESS​ ​in​ ​NEET

2018

PHARMACOLOGY​ ​&​ ​MICROBIOLOGY

1. Area​ ​under​ ​the​ ​blood​ ​concentration​ ​–time​ ​reliably​ ​reflects​ ​the​ ​total​ ​amount
of​ ​drug​ ​reaching​ ​the​ ​target​ ​tissue​ ​after​ ​oral​ ​administration.
2. High​ ​affinity​ ​of​ ​the​ ​drug​ ​will​ ​enable​ ​it​ ​to​ ​be​ ​used​ ​in​ ​low​ ​concentrations.
3. Heparin​ ​can​ ​be​ ​safely​ ​prescribed​ ​in​ ​pregnancy.
4. Tolazoline​ ​is​ ​used​ ​as​ ​a​ ​vasodilator​ ​before​ ​coronary​ ​catheterization.
5. Drug​ ​used​ ​to​ ​perform​ ​stress​ ​ECHO​ ​is​ ​Dobutamine.
6. Used​ ​for​ ​the​ ​treatment​ ​of​ ​migraine,​ ​the​ ​triptans​ ​act​ ​through​ ​5HT-1B.
7. Ipratropium​ ​bromide​ ​is​ ​absolutely​ ​contraindicated​ ​in​ ​urinary​ ​retention.
8. Rofecoxib​ ​is​ ​associated​ ​with​ ​highest​ ​cardiac​ ​mortality.
9. The​ ​therapeutic​ ​efficacy​ ​of​ ​antihypertensive​ ​drugs​ ​is​ ​blunted​ ​by​ ​NSAIDs
because​ ​they​ ​decrease​ ​the​ ​synthesis​ ​of​ ​vascular​ ​prostacyclin.
10. Aspirin​ ​inhibits​ ​Cyclooxygenase.
11. A​ ​patient​ ​on​ ​aspirin​ ​will​ ​have​ ​increase​ ​in​ ​bleeding​ ​time.
12. Misoprostol​ ​is​ ​a​ ​Prostaglandin​ ​E1​ ​analogue.
13. Long​ ​acting​ ​β2​ ​adrenoreceptor​ ​agonist​ ​is​ ​Salmeterol.
14. Zafirlukast​ ​acts​ ​as​ ​a​ ​leukotriene​ ​receptor​ ​antagonist.
15. Hypokalemia​ ​is​ ​a​ ​side​ ​effect​ ​of​ ​beta​ ​2​ ​agonist.
16. Mode​ ​of​ ​action​ ​of​ ​theophylline​ ​is​ ​Phosphodiesterase​ ​inhibitor.
17. Phenylbutazone​ ​if​ ​used​ ​along​ ​with​ ​tolbutamide​ ​(sulfonylurea),​ ​may​ ​cause
hypoglycemia.
18. Hemolysis​ ​is​ ​not​ ​caused​ ​by​ ​Erythromycin.
19. Thiazides​ ​can​ ​cause​ ​hypokalemic​ ​metabolic​ ​alkalosis.
20. Furosemide​ ​is​ ​used​ ​in​ ​pulmonary​ ​edema.
21. Sodium​ ​reabsorption​ ​in​ ​PCT​ ​is​ ​prevented​ ​by​ ​Mannitol.
22. Digoxin​ ​is​ ​contraindicated​ ​in​ ​hypertrophic​ ​obstructive​ ​cardiomyopathy.
23. SLE​ ​is​ ​caused​ ​by​ ​Procainamide.
24. Isosorbide​ ​mononitrate​ ​does​ ​not​ ​undergo​ ​first​ ​pass​ ​metabolism.
25. Quinidine​ ​is​ ​contraindicated​ ​in​ ​Digitalis​ ​toxicity.
26. Sodium​ ​nitroprusside​ ​infusion​ ​may​ ​result​ ​In​ ​cyanide​ ​toxicity.
27. Loeffler's​ ​syndrome​ ​is​ ​an​ ​indication​ ​for​ ​the​ ​use​ ​of​ ​corticosteroids.
28. Buprenorphine​ ​is​ ​an​ ​opioid​ ​with​ ​strong​ ​analgesic​ ​property.
29. Naltrexone​ ​is​ ​used​ ​in​ ​a​ ​case​ ​of​ ​opioid​ ​dependence​ ​to​ ​treat​ ​withdrawal
symptoms.
30. Carbamazepine​ ​can​ ​be​ ​used​ ​with​ ​MAO​ ​inhibitors.
31. Neostigmine​ ​increases​ ​gastrointestinal​ ​motility.
32. Drug​ ​implicated​ ​for​ ​prolonging​ ​QT​ ​interval​ ​in​ ​a​ ​premature​ ​baby​ ​is​ ​Cisapride
33. Anti-coagulant​ ​of​ ​choice​ ​in​ ​heparin​ ​induced​ ​thrombocytopenia​ ​is
Argatroban.
34. Antagonist​ ​of​ ​heparin​ ​is​ ​Protamine​ ​sulfate.
35. Erythromycin​ ​Is​ ​Given​ ​In​ ​Intestinal​ ​Hypomotility​ ​Because​ ​It​ ​Binds​ ​To
Motilin​ ​Receptors.
36. Itraconazole​ ​is​ ​used​ ​for​ ​treating​ ​aspergillosis.
37. Morphine​ ​for​ ​pain​ ​is​ ​not​ ​to​ ​be​ ​used​ ​in​ ​biliary​ ​colic.
38. Fluoxetine​ ​is​ ​a​ ​Serotonin​ ​uptake​ ​inhibitor.
39. Drug​ ​of​ ​choice​ ​for​ ​chronic​ ​myeloid​ ​leukemia​ ​is​ ​Imatinib.
40. ATRA​ ​is​ ​useful​ ​in​ ​the​ ​treatment​ ​of​ ​Promyelocytic​ ​leukemia.
41. Leucovorin​ ​is​ ​used​ ​as​ ​Rescue​ ​therapy​ ​for​ ​patients​ ​who​ ​are​ ​on
Methotrexate.
42. Germ​ ​theory​ ​was​ ​given​ ​by​ ​Louis​ ​Pasteur.​ ​He​ ​is​ ​the​ ​Father​ ​of​ ​microbiology.
He​ ​laid​ ​the​ ​principles​ ​of​ ​sterilization​ ​and​ ​disinfection.
43. Principles​ ​of​ ​asepsis​ ​in​ ​surgery​ ​was​ ​introduced​ ​by​ ​Joseph​ ​Lister.
44. Robert​ ​Koch​ ​discovered​ ​the​ ​causative​ ​organism​ ​for​ ​tuberculosis​ ​and
Cholera.
45. Prokaryotes​ ​have​ ​N​ ​acetyl​ ​muramic​ ​acid​ ​and​ ​N​ ​acetyl​ ​glucosamine​ ​in​ ​their
cell​ ​wall.​ ​They​ ​lack​ ​nuclear​ ​membrane​ ​and​ ​cytoplasmic​ ​organelles.
46. The​ ​cell​ ​wall​ ​of​ ​gram​ ​negative​ ​bacteria​ ​contains​ ​Lipopolysaccharide,
periplasmic​ ​space​ ​and​ ​outer​ ​membrane.
47. Prions​ ​are​ ​least​ ​susceptible​ ​to​ ​disinfectants​ ​and​ ​antiseptics.
48. Thermal​ ​death​ ​point​ ​is​ ​the​ ​lowest​ ​temperature​ ​that​ ​kills​ ​all​ ​microbes​ ​in​ ​10
min
49. Isograft​ ​is​ ​best​ ​suited​ ​for​ ​renal​ ​transplantation.
50. In​ ​transplantation​ ​reaction,​ ​Eichwald​ ​–​ ​Silmer​ ​effect​ ​is​ ​unilateral​ ​sex​ ​linked
histocompatibility
51. Most​ ​common​ ​agent​ ​associated​ ​with​ ​neonatal​ ​bacterial​ ​meningitis​ ​is
Streptococcus​ ​agalactiae​ ​and​ ​E.coli.
52. Identification​ ​of​ ​possible​ ​high-risk​ ​births​ ​by​ ​rectal​ ​and​ ​lower​ ​vaginal​ ​swabs
at​ ​35-37​ ​weeks​ ​of​ ​pregnancy​ ​is​ ​most​ ​likely​ ​to​ ​reduce​ ​the​ ​incidence​ ​of​ ​group​ ​B
streptococcal​ ​disease​ ​in​ ​an​ ​infant.
53. Neisseria​ ​species​ ​in​ ​that​ ​the​ ​pathogenic​ ​species​ ​grow​ ​well​ ​in​ ​enriched
media.
54. Meningococci​ ​differ​ ​from​ ​gonococci​ ​in​ ​the​ ​presence​ ​of​ ​a​ ​polysaccharide
capsule.
55. Pasteurella​ ​multocida​ ​is​ ​oxidase​ ​and​ ​catalase​ ​positive​ ​and​ ​does​ ​not​ ​grow
on​ ​MacConkey​ ​agar.​ ​It​ ​is​ ​commensal​ ​in​ ​URT​ ​of​ ​several​ ​animals,​ ​Eg.​ ​dogs/​ ​cats.​ ​It
causes​ ​wound​ ​infections​ ​of​ ​cat​ ​and​ ​dog​ ​bites.
56. Francisella​ ​tularensis​ ​is​ ​a​ ​gram​ ​negative​ ​bacillus​ ​which​ ​causes
tularaemia/Rabbit​ ​fever.​ ​Voles,​ ​rabbits,​ ​and​ ​muskrats​ ​are​ ​reservoir​ ​hosts.​ ​Most
common​ ​type-ulceroglandular​ ​(60-70%).
57. About​ ​50%​ ​of​ ​world​ ​population​ ​affected.​ ​80-85%​ ​of​ ​population​ ​is​ ​infected​ ​in
some​ ​developing​ ​countries.
58. H.​ ​aegyptius​ ​causes​ ​pink​ ​eye​ ​and​ ​Brazilian​ ​purpuric​ ​fever.
59. Mycoplasma​ ​needs​ ​cholesterol​ ​and​ ​other​ ​lipids​ ​for​ ​growth.
60. Rickettsia​ ​are​ ​gram​ ​negative​ ​coccobacilli,​ ​obligate​ ​intracellular,​ ​form
basophilic​ ​inclusion​ ​bodies​ ​that​ ​stain​ ​with​ ​Castaneda​ ​or​ ​Giemsa​ ​stain.
61. The​ ​tubercle​ ​bacillus​ ​was​ ​discovered​ ​by​ ​Robert​ ​Koch.
62. National​ ​Institute​ ​of​ ​Tuberculosis​ ​is​ ​located​ ​at​ ​Bangalore.
63. Quantitative​ ​assays​ ​like​ ​plaque​ ​assay​ ​and​ ​pock​ ​assay​ ​are​ ​done​ ​for
quantifying​ ​the​ ​number​ ​of​ ​infectious​ ​virus​ ​particles
64. Quantal​ ​assays​ ​indicate​ ​only​ ​presence​ ​or​ ​absence​ ​of​ ​infectious​ ​viral
particles.
65. Parvovirus​ ​B19​ ​has​ ​a​ ​single​ ​stranded​ ​DNA​ ​genome.​ ​It​ ​is​ ​the​ ​smallest
pathogenic​ ​virus.
66. Cytomegalovirus​ ​(CMV)​ ​remains​ ​latent​ ​in​ ​salivary​ ​glands​ ​and​ ​kidneys.
67. Hepatitis​ ​A​ ​virus​ ​belongs​ ​to​ ​genus​ ​Enterovirus​ ​of​ ​family​ ​Picornavirus.
Nonenveloped​ ​ss​ ​RNA​ ​virus.
68. Feco-oral​ ​transmission.​ ​No​ ​chronic​ ​complications.
69. Myxovirusese​ ​like​ ​Influenza​ ​virus​ ​are​ ​cultured​ ​on​ ​amniotic​ ​cavity​ ​and
allantoic​ ​cavity​ ​of​ ​chick​ ​embyo.
70. Orthomyxoviruses​ ​(Influenza​ ​virus)​ ​have​ ​a​ ​segmented​ ​genome.​ ​Genetic
recombinant​ ​strains​ ​due​ ​to​ ​this​ ​kind​ ​of​ ​genome.
71. Arbovirus​ ​are​ ​transmitted​ ​by​ ​insect​ ​vectors.
72. The​ ​primary​ ​reason​ ​for​ ​the​ ​replacement​ ​of​ ​live​ ​oral​ ​polio​ ​vaccines​ ​by
inactivated​ ​polio​ ​vaccine​ ​in​ ​many​ ​countries​ ​where​ ​polio​ ​has​ ​been​ ​eradicated​ ​is​ ​a
greater​ ​risk​ ​of​ ​vaccine-induced​ ​disease​ ​than​ ​wild-virus​ ​induced​ ​disease.
73. Prion​ ​diseases​ ​(transmissible​ ​spongiform​ ​encephalopathies)​ ​are​ ​scrapie​ ​in
sheep,​ ​CJD​ ​in​ ​humans​ ​and​ ​mad-cow​ ​disease​ ​in​ ​cattle.
74. The​ ​trophozoite​ ​of​ ​E.​ ​histolytica​ ​extends​ ​ectoplasmic​ ​pseudopodia​ ​rapidly.
The​ ​nuclear​ ​membrane​ ​is​ ​lined​ ​by​ ​fine​ ​chromatin.
75. Toxoplasmosis​ ​in​ ​fetus​ ​is​ ​best​ ​confirmed​ ​by​ ​IgM​ ​antibodies​ ​against
Toxoplasma​ ​in​ ​fetus
76. Human​ ​diphyllobothriasis​ ​results​ ​from​ ​consuming​ ​infected​ ​fresh-water​ ​fish
with​ ​plerocercoid​ ​larva.
77. Taenia​ ​saginata​ ​spreads​ ​to​ ​man​ ​from​ ​eating​ ​poorly​ ​cooked​ ​cow​ ​meat​ ​with
the​ ​larval​ ​stage​ ​called​ ​cysticercus​ ​bovis.
78. Eosinophilic​ ​meningitis​ ​is​ ​caused​ ​by​ ​Angiostrongylus​ ​cantonensis.
79. Ova​ ​eggs​ ​with​ ​terminal​ ​spine​ ​is​ ​a​ ​feature​ ​of​ ​Schistosoma​ ​haematobium.
80. Sporangiospores​ ​are​ ​formed​ ​in​ ​asexual​ ​reproduction​ ​of​ ​zygomycetes.
81.​ ​ZYgomycosis/Mucormycosis/Phycomycosis​ ​most​ ​often​ ​presents​ ​as
rhinocerebral​ ​disease.
82. Erythromycin​ ​Is​ ​Given​ ​In​ ​Intestinal​ ​Hypomotility​ ​Because​ ​It​ ​Binds​ ​To
Motilin​ ​Receptors
83. Mechanism​ ​of​ ​Multi​ ​Drug​ ​Resistance​ ​Is​ ​Mainly​ ​Acquired​ ​Through​ ​Mutation
In​ ​The​ ​DNA
84. The​ ​Cephalosporin​ ​which​ ​Can​ ​Be​ ​Used​ ​In​ ​↓GFR:​ ​Cefoperazone
85. The​ ​Dose​ ​Of​ ​Which​ ​Of​ ​The​ ​Following​ ​Cephalosporins​ ​Is​ ​Not​ ​To​ ​Be
Decreased​ ​In​ ​Kidney​ ​Failure:​ ​Cefoperazone
86. A​ ​Girl​ ​On​ ​Sulphonamides​ ​Developed​ ​Abdominal​ ​Pain​ ​And​ ​Presented​ ​To
Emergency​ ​With​ ​Seizure.​ ​Acute​ ​Intermittent​ ​Porphyria​ ​is​ ​the​ ​probable​ ​cause.
87. Cefipime​ ​inhibits​ ​cell​ ​wall​ ​synthesis.
88. Ciprofloxacin​ ​is​ ​An​ ​Anti​ ​–​ ​Pseudomonal​ ​Antibiotic
89. Cefaclor​ ​is​ ​Not​ ​Used​ ​For​ ​Methicillin​ ​Resistant​ ​Staph.​ ​Aureus​ ​(MRSA)
Cefaclor
90. ACE​ ​Inhibitor​ ​is​ ​Contraindicated​ ​In​ ​Pregnancy
91. Piperacillin​ ​is​ ​Effective​ ​in​ ​Pseudomonas​ ​Infection
92. Treatment​ ​of​ ​Choice​ ​for​ ​Neurosyphilis​ ​is​ ​Penicillin​ ​G
93. Amikacin​ ​is​ ​not​ ​Effective​ ​In​ ​Treatment​ ​Of​ ​Typhoid.
94. Streptomycin​ ​Is​ ​Nephrotoxic
95. Doxycycline​ ​Inhibit​ ​Protein​ ​Synthesis
96. Streptomycin​ ​And​ ​Other​ ​Aminoglycosides​ ​Inhibit​ ​Bacterial​ ​Protein
Synthesis​ ​By​ ​Binding​ ​To​ ​30S​ ​Ribosomal​ ​Particles.
97. Tetracycline​ ​is​ ​The​ ​Most​ ​Effective​ ​Agent​ ​In​ ​The​ ​Treatment​ ​Of​ ​Rickettsia
Infections
98. Pentamidine​ ​is​ ​Used​ ​In​ ​Pneumonia​ ​Caused​ ​By​ ​P.​ ​Carcinii
99. Compared​ ​With​ ​Most​ ​Other​ ​Cephalosporins,​ ​The​ ​Administration​ ​Of
Cefoperazone,​ ​Or​ ​Cefotetan​ ​Is​ ​Associated​ ​With​ ​A​ ​Higher​ ​Incidence​ ​of​ ​Bleeding
Tendencies​ ​In​ ​Patients​ ​Taking​ ​Warfarin
100. The​ ​Amikacin​ ​Differs​ ​From​ ​Gentamicin​ ​Mainly​ ​In​ ​That​ ​It​ ​Has​ ​Broadest
Spectrum​ ​Against​ ​Gram-Negative​ ​Bacilli

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