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Psy CP F
Psy CP F
CASE PRESENTATION ON
“BIPOLAR AFFECTIVE DISORDER”
In Informants’ words:
Bahut jayada bolti hai, nonstop
Ek jagah pr nhi baith pati h, aur gaali bhi deti hai.
TREATMENT HISTORY
Drug: She seek Dr. Kushagra with her condition of episodic headache and anxiety.
Cap. Betacap TR (40) OD
Tab. Nexitoplus OD
Cap. Cocid DSR OD
Tab. Naxdon 250 SOS
Syp. Overyme 2tsf TDS×5 days
She also went to Noormanzil Psy. Hospital, Lucknow, 1.5 year ago where doctor prescribed
following drugs:
Tab. Lithosum 300 mg
Tab. Nexito
ECT: Not done
Psychotherapy: Not specified
Family Therapy: Not specified
Rehabilitation: Not specified
V. FAMILY HISTORY
S.no Name Age Gender Education Occupation Relation Health
with history
patient
1. Shyam 58 yr. Male 10th std Farming Father Had
cardiac
disease
2. Geeta 53 yr. Female Illiterate Housewife Mother well
3. Ajay 37 yr. Male Graduation Farming Husband Well
kumar
4. Arvind 38 yr. Male 12 Std Business Brother Well
5. Sudha 31 yr. Female 12 Std Housewife Sister Well
6. Vandana 29 yr. Female MA Housewife Patient Ill
7. Khushbu 6 yr. Female - - Daughter Well
8. Nitin 2.5 Male - - Son Well
yr.
29 37
Family tree key:
Male
Female
Female patient
2. Childhood History
Primary caregiver: Mother
Feeding: Breastfeeding
Age at weaning: at 9 months
Developmental milestones: Normal
Behaviour and emotional problems: no any specific problem was present
Illness during childhood: Not present
3. Education History
Age beginning of formal education: At 5 years
Academic performance: she was good at her studies as per her mother
Extracurricular achievement: use to participate in curriculum activities
Relationships with peers and teachers: good
School phobia: Not present
Conduct Disorder: Not present
4. Play History
Game played: with doll along with play mates
Relationship with playmates: was good and cheerful
6. Puberty
Age at appearance of secondary sexual characteristic: 12 years
Anxiety related to puberty changes: not present
Age at menarche: 15years
Reaction to menarche: normal, was not anxious
Regularity of cycle, duration: had regular, 30 days cycle but irregular while taking medicine
since 2019
Abnormality: not present
7. Obstetrical History
LMP: 16/06/2021
Number of children: 2
Any abnormality: absent
9. Premorbid Personality
Interpersonal relationships: Extrovert
Family and social relationships: involve happily
Use of leisure time: doing household chores, knitting sweater etc
Predominant mood: cheerful
Usual reaction to stressful event: become anxious and sad
Attitude to self and other: happy with her achievements
Attitude to work and responsibility: patient taking responsibility very effectively
Religious beliefs and moral attitudes: have faith in god
Fantasy life: not specified
Eating pattern: regular
Elimination: regular
Sleep: less than normal (3 hours a day and half hour in afternoon)
Use of drugs, tobacco, alcohol: absent
B. SPEECH
Initiation: spontaneous
Reaction time: shortened
Rate: Rapid
Productivity: pressure
Volume: increased
Tone: high pitch
Relevance: sometimes off target
Stream: flight of ideas, circumstantiality and tangentiality
Clang association: Absent
Coherence: loose association
Other: Echolalia
Sample
Question: Aaj kaisa lga raha hai aapko?
Answer: Acha lag raha h
Question: Aap samaaj ke liye kya krna chahti h?
Answer: Hum chai banyege sbke liye, hamare ghr me 20-liter chai banti h.
D. THOUGHT
Stream: pressure of thought and flight of ideas
Form: Understandable
Delusion: Grandeur
Ideas: Flight of Ideas
Thought alienation phenomena: Absent
Obsessional /compulsive phenomena: Absent
Phobias: not specified
E. PERCEPTION
Illusions: Absent
Hallucinations: patient complains for hearing sound of beetle (Cricket)
Somatic passivity: Not specified
Deja vu / jamais vu: Not present
Depersonalization / derealization: Present
5. Memory:
Difficult in recalling 3 objects (Hawa, pankha, paani)
Unable to recall her breakfast meal fully.
6. Remote
Personal event: Aware about various hospitals she went for treatment previously.
Impersonal events:
Not specified
Illness- related events:
Not clearly defined
7. Intelligence
Question: Yahan ke mukhya mantri kon h?
Answer: Yogi ji
Arithmetic: Able to solve equation of sum, subtraction, multiplication and division too
8. Abstraction
Interpretation of proverb
Ankho ka tara: Bhaut pyara
9 do Gyarah ho jana: Bhaag jana, paisa lekar bhaag gya
Similarities between Object:
Kitab or copy: Could not tell
Difference: Kitab se padhte h, padhai ki jati h
9. Judgement
Person-
Question: Aap yahan se theek hokr jab ghr jayegi to kya krengi?
Answer: Hum Pdhenge, khana banayenge, kaam karenge, tehlenge,Vidhayak banege, achaar banayenge.
Inference: Impaired
Social-
Question: Aap samaaj ke liye kuch karna chahti h?
Answer: Chai banayenge sbke liye
Inference: Impaired
Test-
Question: Agr aapka exam ho, or koi aapse bahar ghumne jaane ke liye bole tb aap kya krengi?
Answer: Patient starts to shout
Inference: Impaired
G. INSIGHT
1 Complete denial of illness but sometimes her insight lies in Grade 2
INVESTIGATION DONE
1. Complete hemogram-
INTERPRETATION:
The YMRS total score ranges from 0 to 60 where higher scores indicate more severe mania, thus, a negative
change (or decrease) from baseline indicates a reduction (or improvement) in manic symptoms. Total score:
≤12 indicates remission
13-19=minimal symptoms
20-25=mild mania
26-37=moderate mania
38-60=severe mania
TREATMENT
S. no. DRUG NAME DOSE FREQUENCY
1. Tab. Clonazepam 4mg OD
2. Tab. Olanzapine 25 mg BD
3. Tab. Chlorpromazine 300 OD
4. Tab. Lithium 1200 mg OD
5. Tab. Valproate 100 mg BD
6. Inj. Haloperidol+ Inj. Phenergan 0.5 mg + 25 mg Stat
HISTORICAL PRESPECTIVE
Documentation of the symptoms associated with bipolar disorder dates back to about the second century in
ancient Greece.
Aretaeus of Cappadocia, a Greek physician, is credited with associating these extremes of mood as part of
the same illness. He described patients who could at times laugh and play all night and day but at other times
appeared “torpid, dull and sorrowful”.
His view that these moods swings were part of the same illness did not gain acceptance until much later.
The modern concept of manic- depressive illness began to emerges in the 19th century. In 1854, Jules
Baillarger presented information to the French Imperial Academy of Medicine which he used the term Dual-
form insanity to describe the illness.
In the same year, Jean-Pierre Falret described the same disorder, one with alternating periods of Depression
and manic excitation, with the term circular insanity, who also noticed that this disorder appeared to have
genetic underpinnings, a belief that is adhered today.
Contemporary thinking about bipolar disorder has been shaped by the works of Emil Krapelin, who first
coined the term Manic-Depressive in 1913. He added that this disorder was characterized by acute episodes
followed by relatively symptom- free periods.
In 1980, The American Psychiatric Association adopted the term Bipolar disorder as the diagnostic category
for manic- depressive illness in the third edition of Diagnostic and statistical Manual of Mental Disorders.
This term identified a period of mood elevation and excitation as a defining characteristic of the disorder
that distinguishes it from other mood or psychotic disorders.
DEFINITION
“A disorder associated with episodes of mood swings ranging from depressive lows to manic highs.”
INCIDENCE
Bipolar disorder affects approximately 5.7 million American adults, or about 2.6 % of the US population
aged 18 and older in a given year.
Of these cases 82. 9 % are considered severe (National Institute of Mental Health, NIMH, 2015)
In terms of gender, the incidence of bipolar disorder is roughly equal, with a ratio of women to men of about
1.2 to 1.
The average age of onset for bipolar disorder is 25 years and following the first manic episode, the disorder
tends to be recurrent. Unlike depressive disorders, bipolar disorder appears to occur more frequently among
the higher socioeconomic classes.
Bipolar disorder is the sixth leading cause of disability in the middle- age group, but for those who respond
to lithium treatment (about 33% of those treated within lithium), bipolar disorder is completely treatable,
with no further episodes.
CLASSIFICATION
Bipolar Disorder I
It is diagnosis given to an individual who is experiencing a manic episode or has a history of one or more
manic episodes. The client may also have experienced of depression this diagnosis is further specified by the
current and most recent behavioral episodes experienced.
Bipolar Disorder II
It is characterized by recurrent bouts of major depression with episodic occurrence of Hypomania.
The individual who is assigned this diagnosis may present with symptoms of depression or hypomania. The
client has never experienced a full manic episode, and the symptoms are “not severe enough to cause
marked impairment in social or occupational functioning or to necessitate hospitalization”.
The diagnosis may specify whether the current or most recent episode is hypomanic, depressed or with
mixed features. If the current syndrome is a major depressive episode, psychotic or catatonic features may
be noted.
Cyclothymic Disorder
The essential feature of cyclothymic disorder is a chronic mood disturbance of at least 2 years duration,
involving numerous periods of elevated mood that do not meet the criteria for a hypomania episode and
numerous periods of depressed mood of insufficient severity or duration to meet the criteria for major
depressive episode.
The individual is never without the symptoms for more than 2 months.
Substance/ Medication – Induced bipolar Disorder
The disturbance of mood associated with this disorder is considered to be the direct result of physiological
effects of a substance (e.g., ingestion of or withdrawal from a drug of abuse or a medication).
The mood disturbance may involve elevated, expansive or irritable mood with inflated self-esteem,
decreased need for sleep and distractibility. The disorder cause clinically significantly distresses or
impairment in social, occupational or other important areas of functioning.
Mood disturbances are associated with intoxication from substances such as alcohol, amphetamines,
cocaine, hallucinogens, inhalants, opioids, phencyclidine sedatives, hypnotics and anxiolytics. Symptoms
can also occur during withdrawal from substances such as alcohol, amphetamines, cocaine, sedative,
hypnotics and anxiolytics.
A number of medications have been known to evoke mood symptoms. Classification includes anesthetics,
analgesics, anticholinergics, anticonvulsants, antihypertensives, antiparkinsonian, agents, antiulcer agents,
cardiac medications, oral contraceptives, psychotropics medications, muscle relaxants, steroids and
sulfonamides. Some specific examples are included in the discussion of predisposing factors associated with
bipolar disorder.
Bipolar Disorder Due to Another Medical Condition
This disorder is characterized by and persistently elevated or irritable mood and excessive activity or energy
judged to be the direct psychological consequences of another medical condition.
The mood disturbance causes clinically significant distress or impairment in social, occupational or other
important areas of functioning. Types of physiological influences are included in the discussion of
predisposing factors associated with bipolar disorder.
ETIOLOGY
BOOK PICTURE1 PATIENT PICTURE
1. GENETIC -
Bipolar disorder strongly reflects an underlying
genetic vulnerability. It has been found that
schizophrenia and bipolar disorders had about 15 %
of genetic variation in common
2. TWIN STUDIES -
Bipolar disorder among monozygotic twins has
identical genes, compared to 10-20 % in dizygotic
twins
3. FAMILY DISORDER -
If one parent has a mood disorder, the risk that a
child will have a mood disorder is between 10-25
%, If both parents have the disorder, the risk is 2-3
times greater
4. OTHER GENETIC STUDIES -
ANK3 protein, located on the first part of
the axon, is involved in making the
determination of whether a neuron will fire,
Its increase expression may cause mania
symptoms.
CACNA1C protein regulates the influx and
outflow of calcium channel blockers
sometimes used in the treatment of Bipolar
Disorder
5. BIOGENIC AMINES -
Functional Excess of norepinephrine and
dopamine is associated with Mania
SSRI sometimes triggers the manic episodes
and rapid cycling of mood swings in client
with bipolar disorder
Acetylcholine is another neurotransmitter
believed to be related to symptoms in
bipolar disorder]
Excessive levels of Glumate, an excitatory
neurotransmitter, have been associated with
bipolar disorder
6. NEUROANATOMICAL FACTORS -
Dysfunction in the prefrontal cortex, basal
ganglia, temporal and frontal lobes of the
forebrain and part of the limbic system
including the amygdala, thalamus and
striatum
As per Sadock and associates report widely
replicated positive emission tomography
PET demonstrates decreased anterior brain
function on the left side in depression and
greater right-side reduction in brain activity
in mania.
7. MEDICATION SIDE EFFECT -
Steroid’s medication used to treat chronic
illness such as multiple sclerosis and
systemic lupus erthematousus.
Amphetamines, antidepressants and high
doses of anticonvulsant and narcotics also
have the potential for initiating a manic
episode
9. THE TRANSACTIONAL MODEL OF STRESS Patient’s stress adaptation capabiltiy was also poor
AND ADAPTATION
CLINICAL MANIFESTATIONS
Symptoms of manic state can be described according to three stages: Hypomania, Mania and Delirious
TREATMENT
Antipsychotics. If symptoms of
depression or mania persist in spite of
treatment with other medications,
adding an antipsychotic drug such as
Tab. Olanzapine
olanzapine (Zyprexa), risperidone
(Risperdal), quetiapine (Seroquel),
aripiprazole (Abilify), ziprasidone
(Geodon), lurasidone (Latuda) or
asenapine (Saphris) may help. These
medications alone or along with a
mood stabilizer.
Antidepressant-antipsychotic. The
medication Symbyax combines the
antidepressant fluoxetine and the
antipsychotic olanzapine. It works as a
depression treatment and a mood
stabilizer.
Anti-anxiety
medications. Benzodiazepines may
help with anxiety and improve sleep,
but are usually used on a short-term
basis.
NURSING MANAGEMENT
1.) Nursing Assessment
Assessment of a patient with bipolar disorder include:
HISTORY- Taking a history with a client in a manic phase often proves difficult; obtaining data in several
short sessions, as well as talking to family members, may be necessary.
GENERAL APPEARANCE AND MOTOR BEHAVIOUR- Client with mania experience psychomotor
agitation and seem to be in continuous motion; sitting still is difficult; this continual movement has many
consequences; clients can be exhausted or injure themselves.
MOOD AND AFFECT- Mania is reflected in periods of euphoria, exuberant activity, grandiosity, and false
sense of wellbeing.
THOUGHT PROCESS AND CONTENT- Cognitive ability or thinking is confused and jumbled with
thoughts racing one after another, which is often referred to as flight of ideas; clients cannot connect
concepts, and they jump from one subject to another.
PROGNOSIS
Prognosis of patient is based on following factors:
Bipolar Disorder – Good and Poor prognostic Factors
Good prognostic Factors Poor prognostic Factors
Abrupt or acute onset Double depression
Severe depression Comorbid physical disease, personality
Typical clinical features disorder or alcohol dependence
Well-adjusted premorbid personality Chronic ongoing stress
Good response to treatment Poor drug compliance
Marked hypochondriacal feature or mood
incongruent psychotic feature
My Patients Prognosis
Day 1: Patient was irritable, anxious and do not want to talk
Day 2: Try to maintain rapport with patient.
Day 3: Patient was expressive, her symptoms were at peak for example increased libido, high pitch, volume
speech, hyperactivity etc.
Day 4: Patient wants to be involved in activities like origami making, drawing but for a short period of time,
complains for visual delusion and delusion of persecution
Day 5: Due to increase excitement of patient and hyperactivity, patient was tended to be sedate. Patient
remains calm due to effect of drug.
SUMMARY:
In this case presentation, I discussed about condition Bipolar Affective Disorder, Patient’s history, mental
status examination, physical examination, Investigation, young mania rating scale which I applied to my
patient, Treatment, about disease condition, its historical perspective, definition, incident, classification,
type, aetiology, clinical manifestation, Investigation, treatment of my patient in comparison to book picture,
Nursing management and nursing care plan after formulating nursing diagnosis as per priority, health
education and prognosis.
CONCLUSION
With the help of this Case Prestation, I was able to understand Bipolar Affective Disorder properly. As is a
common psychiatric disorder characterized by affective instability and cognitive deficits, particularly during
mood episodes and Abnormalities within the ALN and related brain regions appear to be involved in the
neurophysiology of bipolar disorder, it is important to have knowledge and to educate family member so
that they could accept the symptoms of patient and can contribute in the treatment of patient.
BIBLIOGRAPHY
1. Valfre Morrison, Foundations of Mental Health Care, 6 Edition, published by Elsevier, page no: 242-243
2. Boyd Ann Mary, Psychiatric Nursing contemporary practice, sixth edition, published by Wolters Kluwer,
page no: 407-415.
3. Stuart. W Gail, Principles and Practice of Psychiatric Nursing, 10 editions, published by Elsevier, page
no: 292-293
5. Sreevani R, A Guide to Mental Health and Psychiatric Nursing, 4 Edition, published by Jaypee Brothers,
page no,208-210
6. Townsend C Mary, Morgan I Karyn, Psychiatric Mental Health Nursing, Concepts of care in Evidence
Based Practice, 9th Edition, Published by Jaypee Brothers, Page no:542-557