medication FDA approval Maintenance oral dose
phenobarbital Myoclonic, patrial, tonic-
clonic sz and status (all
ages)
phenytoin Partial, tonic-clonic sz and
status (all ages)
lorazepam Status epilepticus (all ages)
diazepam Partial seizures (all ages ˃6
m)
valproate Absence, myoclonic, partial
and tonic-clonic sz (age ˃2y)
Levetiracetam (Keppra) Myoclonic,partial tonic clonic
sz
(age ˃4-6 y)
Carbamazepine Partial and GTC (all ages)
Ox carbamazepine Partial seizure (˃2 y)
lamotrigine LGS, partial and tonic-clonic
seizure (age ˃2 y)
clonazepam Absence seizures, LGS,
myoclonic sz (all ages)
gabapentin Partial sz (˃3 y)
tolpiramate LGS, partial and tonic-clonic
sz (all ages)
Antiepileptic doses
‫اعداد الصيدالنية رحيق رائد رمزي‬
˂5 y 3-5 mg/kg bid or qd
˃5y 2-3 mg/kg bid.qd
˂3y 8-10 mg/kg
˃3y 4-7 mg/kg
(tab or susp. Tid
Cap qd)
0.05-0.1 bid or tid
0.25-1.5 mg/kg bid or tid
o.o1-0.25 IV
0.2-0.5 mg/kg rectal.
15-40 mg/kg (if patient is on
enzyme inducers use higher
doses 60 mg/kg)
Frequency: sprinkle cap. Bid
Solution tid
20-40 mg/kg bid or tid
10-20 mg/kg tid or qid (*4)
SR bid
20-40 mg/kg bid
LGS : 5-15 mg/kg tid
Partial tonic clonic sz: 1-5
mg/kg bid
0.05-0.2 mg/kg bid or tid
30-60 tid
3-9 mg/kg ,slow titration bid
or tid