DRUG STUDY

Patient’s Initials: JM____________________________ Date of Admission: April 25, 2021_______________________ Diagnosis: T/C Osteomyelitis___________
Age: 15 years old _____________________________ Height: 5 ft. 5 inches_ Weight: 152 lbs.___________________ Clinical Intervention: N/A______________
Sex: M_________ ____________________________ Ward: Medical_____ Bed No.:_2________________________Name of Physician: Dr. Arya Greyjoy____

Nursing
Name of Drug Classification Mechanism of Action Indication Contraindication Side Effects
Responsibilities
Generic Name: Pharmacologic Pharmacodynamics or General Indication:  Hypersensitivity to CNS: Chills, Before Drug
Vancomycin Class: Mechanism of Action:  Parenterally for vancomycin depression, dizziness, Administration
hydrochloride Tricyclic Bactericidal action is potentially life-  allergy to corn or fatigue, fever, - Monitor IV site
glycopeptide due to inhibition of cell- threatening corn products headache, insomnia, closely; necrosis and
Trade/Brand Name: derivative wall biosynthesis and infections in patients  Previous hearing vertigo tissue sloughing will
Vancocin alteration of bacterial allergic, loss. result from
Therapeutic cell-membrane nonsensitive, or CV: Hypotension, extravasation.
Minimum dose: Class: permeability and resistant to other less peripheral edema, - Store parenteral
125 mg q6h Antibiotic ribonucleic acid (RNA) toxic antimicrobial vasculitis solutions in
synthesis. Active against drugs refrigerator for up to
Maximum dose: Pregnancy many gram-positive  Used orally only in EENT: Ototoxicity 14 days; after further
500 mg q6h Category: organisms. Clostridium difficile dilution, parenteral
C colitis and GI: Abdominal pain, solution is stable 24 h
Patient’s Dose: Pharmacokinetics: staphylococccal constipation, at room temperature.
500 mg slow IV Absorption: Not enterocolitis (not Clostridium difficile- - Assess hearing. Drug
infusion over 1 hour, absorbed. effective by oral associated diarrhea, may cause damage to
and then q 6hrs round route for treatment diarrhea, flatulence, auditory branch (not
the clock Peak: 30 min after end of systemic nausea, vomiting vestibular branch) of
of infusion. infections) eighth cranial nerve,
Route: GU: Nephrotoxicity, with consequent
IV Infusion Distribution: Diffuses Patient’s Indication: UTI deafness, which may
 into pleural, ascitic, Treatment for patient’s be permanent.
Frequency: pericardial, and synovial bacterial infection (Wound HEME: Anemia,
slow IV infusion over fluids; small amount culture and sensitivity: eosinophilia, During Drug
1 hour, and then q 6hrs penetrates CSF if Heavy growth of neutropenia, Administration
round the clock meninges are inflamed Staphylococcus aureus- thrombocytopenia - To reconstitute 500-
methicillin resistant) mg vial of vancomycin
Availability: Elimination: 80–90% of MS: Back pain R for I.V. use, add 10 ml
Capsule IV dose in urine within of sterile water for
Oral Solution 24 h ESP: Dyspnea, injection; further dilute
IV Infusion wheezing with at least 100 ml of
Half-Life: 4–8 h. compatible I.V.
Content: SKIN: Exfoliative solution.
Vancomycin, FD&C dermatitis; drug rash - Avoid rapid infusion,
Blue No. 2, gelatin, with eosinophilia and which may cause
iron oxide, systemic symptoms sudden hypotension.
polyethylene glycol, (DRESS); exfoliative - Monitor BP and heart
titanium dioxide dermatitis; rate continuously
extravasation with through period of drug
pain, tenderness, administration.
thrombophlebitis, and
tissue necrosis; After Drug
pruritus; rash; Stevens- Administration
Johnson syndrome; - Notify prescriber
toxic epidermal promptly of ringing in
necrolysis; urticaria ears.
- Observe I.V. infusion
Other: Anaphylaxis, site for evidence of
drug-induced fever, extravasation,
hypokalemia, including necrosis,
injection-site pain, tenderness, and
inflammation, thrombophlebitis. If
 superinfection extravasation occurs,
discontinue infusion
immediately and notify
prescriber.

References:

Vallerand, A., Sanoski, C., & Deglin, J. (2017). Drug Guide for Nurses. 15th Ed. FA Davis Company: Philadelphia

Schull, P. D. (2013). McGraw-Hill nurses drug handbook. New York: McGraw-Hill Medical.

JONES & BARTLETT LEARNING. (2018). Nurses Drug Handbook. SUDBURY.