Gulf Association of Endocrinology & Diabetes

(GAED)
Virtual Conference
October 7-9, 2021

Prevalence & Epidemiological Characteristics Of Grave’s Disease

Among Omanis Patients Attending SQUH
Al Saliti F, Al Futaisi A

AIM RESULTS
This retrospective study aimed to find out the prevalence and
epidemiological features of Graves’ disease (GD) among Omani
patients with thyroid abnormalities as well as determine treatment
options available in Sultan Qaboos University Hospital (SQUH).

INTRODUCTION

The prevalence and epidemiological feature of graves disease had

not been well studied in Oman And in SQUH specifically, so this
study will provide good information to SQUH and public health
databases about GD, as well as finding out the risk factors
associated with GD will help in decreasing morbidity and mortality
rate in those group of patients.

BACKGROUND Figure: patients’ distribution among age groups

Graves' disease (GD) is referred to a common disorder that

effected the endocrine system(Usman, 2000). The Table : radiological and biochemical features among Graves’ and
Non-Graves’ patients
pathogenesis of GD is when their secretion of autoantibodies
that bind to thyrotropin receptors that stimulate the growth of
the thyroid gland and overproduction of thyroid hormones
(Lafranchi et al., 2011). These antibodies can be used as a
marker for GD and as a predictive value of recurrence after
treating by antithyroid drugs. The prevalence of GD was found
to be 0.5% of the population in the US and 50-80% from all
cases of hyperthyroidism(Girgis et al., 2011). According to a
study was done in KSA the GD is more common in females
than males with a ratio of male: female 1:2.9 (Usman, 2000).

METHODS

This cross-sectional retrospective study was conducted in the

endocrine unit at SQUH with a Sample of 231 participants, where
the sample size was determined by the availability of documented
data. Omani patients were selected at the time of arrival to the
clinic with thyroid abnormalities and underwent thyroid scan (Tc-
99m), thyroid ultrasound and biochemical tests. Data were
collected from the Hospital Information System (HIS), and CONCLOSION
patient’s confidentiality was kept protected. All collected data were
compiled and analysed by special Statistical Package for Social Our study showed a high prevalence of GD (66.2%) with a ratio of
Science (SPSS) version 25.0. Descriptive statistics were presented 1.38:1 female: male. Also GD was significantly associated with
as a mean ± standard deviation, frequencies, and percentages. radiological features(present of nodule), thyroid reuptake scan
Categorized and continuous variables were analysed by using the finding, and biochemical finding (TSH, F4, TRAb) which will
Chi-square test and presented with numbers and percentages to help in early detection and management of GD
determine the relationship between different variables.

• Girgis, C. M., Champion, B. L. and Wall, J. R. (2011) Current

RESULTS
Among 231 subjects, GD was prevalent in 66.2% were 67.1%
female and 32.9%, male. The figure below shows the Distribution of
GD among the study sample according to different age groups.
concepts in Graves’ disease, Therapeutic Advances in
Endocrinology and Metabolism, 2(3): 135–144.
https://doi.org/10.1177/2042018811408488.
• Lafranchi, S., Editor, S., Kirkland, J. L., Editor, D. and Hoppin, A.
G. (2011) Clinical manifestations and diagnosis of hyperthyroidism
in children and adolescents, (table 1): 1–12.
• Usman, H. (2000) Original Article Graves ’ disease in Saudi
Arabia : a ten-year hospital study, 302–304.