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Sosc3900 Abnormal Psychology Beatrice Lai
Sosc3900 Abnormal Psychology Beatrice Lai
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SOSC3900 ABNORMAL PSYCHOLOGY
BEATRICE LAI
TEACHING TEAM
• Instructor
• Beatrice LAI
• Office: Room 2387
• Contact: beatricelai@ust.hk, ext 7817
• Consultation: by email appointment (with confirmation)
• TAs
• Vivien PONG
• Contact: sosc3900ta@ust.hk
• Consultation: by email appointment (with confirmation)
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CLASSROOM ETIQUETTES
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CLASSROOM ETIQUETTE
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CLASSROOM ETIQUETTE
• Your microphone is
normally muted when you
enter the class
• Raise hand in
“Participants” to request
for speaking up
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CLASSROOM ETIQUETTE
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ABNORMAL PSYCHOLOGY
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TRUE OR FALSE
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TOPICS
• What is abnormality?
• Definition of abnormality
• Mental health professionals
Psychiatrist Counsellor
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TOPICS
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TOPICS
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TOPICS
• Anxiety Disorders
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TOPICS
• Mood Disorders
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TOPICS
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TOPICS
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TOPICS
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ASSESSMENT
Quizzes 30%
Group Project 45%
- Presentation and Q&A (30%)
- Individual Paper (10%)
Film Critique 25%
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QUIZZES (15% + 15%)
• 2 quizzes
• Multiple-choice questions
• Lecture notes and required readings
• No make-up quiz unless for validated medical
reasons
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GROUP PROJECT
PROPOSAL (5%) + PRESENTATION (30%)
• Task: to investigate ONE specific psychological
disorder (one disorder per group other than the
ones listed in the teaching schedule on a first-
come-first served basis)
• Describe the diagnostic criteria of the disorder
• Provide a case vignette (a celebrity or someone you know
in person) of the disorder
• Identify the etiology of the disorder for the case chosen
• Suggest treatment for the case vignette
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GROUP PROJECT – INDIVIDUAL PAPER (10%)
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FILM CRITIQUE (25%)
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TEXTBOOK
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ACADEMIC INTEGRITY
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COURSE COMMUNICATION PLATFORM
• CANVAS
• Announcements
• Lecture materials
• Discussion
• Distribution of scores
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YOUR FEEDBACK
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LECTURE 2-3
WHAT IS ABNORMALITY?
SOSC3900 Abnormal Psychology
2
Abnormal Psychology
• Abnormal psychology is the scientific study whose
objectives are to describe, explain, predict, and modify
behaviors that are considered strange or unusual
• It is concerned with understanding the nature, causes,
and treatment of mental disorders
3
What is Abnormal?
• What is your definition of abnormality?
Case 1
• Judy is a 16-year-old teenager. About 2 years earlier, in Judy’s first
biology class, the teacher showed a movie of frog dissection. This
was a graphic film, with vivid images of blood, tissue, and muscle.
About halfway through, Judy felt light headed and left the room. But
the images did not leave her. She continued to be bothered by them
and occasionally felt queasy. She began to avoid situations in which
she might see blood or injury. She found it difficult to look at raw meat,
or even Band-Aids, because they brought the feared images to mind.
Eventually, anything anyone said that evoked an image of blood or
injury caused Judy to feel lightheaded.
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Case 2
• Danny, a 9-year-old boy, had a great deal of energy and loved playing most sports,
especially soccer. Academically, his work was adequate, although his teacher reported
that his performance was diminishing and she believed he would do better if he paid
more attention in class. Danny rarely spent more than a few minutes on a task without
some interruption: he would get up out of his seat, riffle through his desk, or constantly
ask questions. His peers were frustrated with him because he was equally impulsive
during their interactions: He never finished a game, and in sports he tried to play all
positions simultaneously. At home, his room was a constant mess because he became
engaged in a game or activity only to drop it and initiate something else. Danny’s
parents reported that they often scolded him for not carrying out some task, although
the reason seemed to be that he forgot what he was doing rather than he deliberately
tried to defy him.
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Case 3
• Jimmy is a distinguished lawyer. As an intelligent, good-looking single man, he noted
without bragging that he could have sex with any number of beautiful women in the
course of his law practice. However, the only way he could become aroused was to
leave his office, go down to the bus stop, ride around the city until a reasonably
attractive young woman got on, expose himself just before the next stop, and then run
off the bus, often with people chasing after him. To achieve maximum arousal, the bus
could not be full or empty; there had to be just a few people sitting on the bus, and the
woman getting on had to be the right age. Sometimes hours would pass before these
circumstances lined up correctly. On several occasions he had requested a girlfriend to
role-play sitting on a bus in his apartment. Although he exposed himself to her, he
could not achieve sexual arousal and gratification because the activity just wasn’t
exciting.
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Deviance
Elements of
abnormality
include:
Maladaptiveness
Dangerousness
Social Discomfort
Scarification
The Role of Culture
• Cultural relativism
• Manifestation of disorders varies across culture
Important Terms
• Epidemiology
• The study of the distribution of
mental disorders in a given
population
• Prevalence and incidence
30
Important Terms
Different types
of prevalence
Typically estimates
expressed as
Number of percentages
active cases in
population
Prevalence during any given
period of time
31
Important Terms
• Prevalence
• Point prevalence: the percentage of people who is
suffering from a disorder at a given point in time
Important Terms
• Prevalence
33
Important terms
Incidence
figures are
Number of new typically lower
cases in than prevalence
population over figures
Incidence
given period of
time
34
Important Terms
• Course
• Typical pattern of development and change of a disorder over time
Important terms
• Onset
• The pattern of occurrence of a disorder
Important terms
• Prognosis
• Predicted development of a disorder over time
• Duration of the disorder
• Chances of complications
• Probable outcomes
• Prospects for recovery
• Recovery period
• Mortality rates
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Important terms
• Etiology
• The cause(s) of a mental disorders
• Biopsychosocial model
• Comorbidity
• The presence of two or more disorders in the same person
• Comobidity is especially high in people who have severe forms of
mental disorders
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Required reading
• Chapter 1
Models of Abnormal
Behavior
SOSC3900 Abnormal Psychology
1
Overview
O Etiology
O The Multipath Model
O Biological Dimension
O Psychological Dimension
O Psychodynamic Models
O Behavioral Models
O Cognitive Models
O Humanistic Models
O Social Dimension
O Social Relational Models
O Family Systems Models
O Sociocultural Dimension
2
Etiology
O Why do we have to identify the causes of
mental disorders?
O To treat mental disorders
O To prevent mental disorders
O To diagnose and classify mental disorders
better
3
Multipath Model
4
Biological Dimension
5
Biological Dimension
Genetic vulnerabilities
O Genes
O Long molecules of DNA (deoxyribonuclei acid)
that are present at various locations on
chromosomes
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Human Chromosome Pairs 7
Biological Dimension
O Genetic Vulnerabilities
O Abnormalities in the structure and number of
the chromosomes can be associated with
major defects or disorders
O E.g. Down syndrome is caused by a trisomy in
chromosome 21
O Mental disorders are polygenic (i.e.
influenced by abnormalities or variations in
multiple genes)
8
Biological Dimension
O Unlike some physical characteristics such as eye
color, behavior is not determined exclusively by
genetic endowment; it is a product of the
organism’s interaction with the environment
O Genotype
O A person’s genetic makeup or endowment
O Phenotype
O Observable behavioral and physical
characteristics that result from an interaction of
the genotype and the environment
9
Biological Dimension
O Certain genes can be “turned on” and
“turned off” in response to environmental
influence
O Example: PKU-induced mental retardation
O Children with the genetic vulnerability to PKU
cannot metabolize phenylalanine (an amino
acid)
10
Biological Dimension
Methods for studying genetic influences
O The family history (pedigree) method
O An investigator observes samples of relatives
of each index case to see whether the
incidence increases in proportion to the
degree of hereditary relationship
O The incidence of the disorder in a normal
population is compared with its incidence
among the relatives of the index cases
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O Rates of schizophrenia among relatives of
schizophrenic patients
Type of relative Per cent at risk
First-degree relatives
Parents 4.4
Children 12.3
Brother and sisters 8.5
Second-degree relatives
Uncles and aunts 2.0
Nephews and nieces 2.2
Grandchildren 2.8
Third-degree relatives
First cousins 2.9
General population 0.86 12
Biological Dimension
Methods for studying genetic influences
(look at concordance rate) - percentage
O The twin method having the same trait
O Assess hereditary influence by comparing the
resemblance of identical twins and fraternal
100% same
twins with respect to a trait
50% same
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moderate
very small
generic factor more imp role
(completely 16
env. factor)
Biological Dimension
Brain Dysfunction
O The brain is responsible for: (major roles of brain)
O receiving information from the outside world
O using the information to decide on a course
of action (e.g. MC in quiz)
O implementing decisions
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expression of emotion
18
personality changed
gental person
become
foul mouth, impulsive
social judgement,
socially appropraite
judgement damaged
underlie mental
disorders
O Neurons (nerve cells)
O Dendrites:
O Receive signals from
other neurons
O Axons:
O Send signals to
other neurons
transporting 20
information to other
Biological Dimension
21
axon terminal cannot touch each other
Biological Dimension
22
Biological Dimension
Biochemical imbalance
too much neuron transmitter
O An excess of dopamine is linked to
schizophrenia too much receptors to receive
(caused by) dopamine)
O Excessive postsynaptic dopamine receptors
O Hypersensitivity of receptors to dopamine
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Biological Dimension
O Biology-based treatment techniques:
O Psychopharmacology
O Psychosurgery psychiatrist and neuro surgurist
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Psychological Dimension
Psychodynamic models
traumatic childhood experience
O Adult disorders arise from
socially unacceptable
childhood traumas or anxieties
O Childhood-based anxieties operate
unconscious desire
unconsciously and are repressed
because they are too threatening to
face
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all psychological disorder are due to childhood experience
trace back what happened in childhood
Freud’s Psychosexual Theory (can't testified)
everything is dirty
over:
not enough:
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Which stage is David Beckham fixated at?
Obsessive-compulsive disorder
David Beckham
suffers from OCD and it manifests itself through constant
cleanliness and perfection of all that is around him.
Anything out of order is enough to cause a conflict and
must be attended to immediately. Examples of this
complete order is that everything must be in pairs, if
there are three books on a table one must be added, or
one must be removed. anal 28
28
Psychological Dimension
O Psychodynamic therapy understand unconcious
O Psychoanalysis has three main goals
O Uncovering repressed material
O Helping clients achieve insight into desires and
motivations
O Resolving childhood conflicts that affect
current relationships resolve conflict
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Psychological Dimension
Types of psychoanalysis
O Free association
O Patient says whatever comes to mind for the
purpose of revealing his or her unconscious
goal: relax environment
supportive/non-judgemental
30
Psychological Dimension
Types of psychoanalysis
O Dream analysis
O Dreams represent
unconscious wishes
that dreamers desired
to see fulfilled
O Defenses and inhibition
of the ego weakens
when people sleep,
allowing unacceptable
motives to surface in
dreams
31
Psychological Dimension
O Manifest content:
aspect of dream
which we experience
consciously during
sleep and may
remember upon
awakening
O Latent content: the
unconscious wishes
and thoughts being
expressed by the
dream symbolically
32
Train traveling through a tunnel 33
Psychological Dimension
Types of psychoanalysis
O Interpretation of resistance
O Resistance is a process in which the patient
unconsciously attempts to impede the
psychoanalysis by preventing the exposure of
repressed material
34
Psychological Dimension
Types of psychoanalysis
O Transference
O The unconscious redirection of feelings and
attitudes that the patient had toward
significant others in the past to the analyst
strong affection towards the phyrapist
negative
transferring attitude towards significant others toward
the phyrapist
e.g. strong unacceptable attitude towards others
(forbidden)
35
Psychological Dimension
O Behavioral models observable behaviour, and try to find out why abnormal
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Classical conditioning
O Stimulus – Response connection
O Type of learning in which a neutral stimulus
comes to bring about a response after it is
paired with a stimulus that naturally brings
about that response
all trigger by stimuli
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Pavlov (1927)
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39
a response that, after conditioning, follows a
previously neutral stimulus
repeated pairing
Fears 41
originally Little albert have no fear to white rat
rat
gong UCR
4 different type
44
Operant Conditioning
O Maladaptive behaviors linked to
environmental reinforcers
(alcohol are reinforced)
alcohol are way of escape stress (positive)
45
Discussion
O How can we use operant conditioning to
help an alcoholic to stop abusing alcohol?
46
Bandura’s Social Cognitive Theory
Observational learning
O A process in which an individual learns new
responses by observing what others (the
role model) do and what happens to them
for doing it, instead of through direct
experience
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Bandura, Ross, & Ross (1963)
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Bandura’s Social Cognitive Theory
Observational Learning
O Assumes that abnormal behavior is learned
in the same way as normal behavior
O Exposure to disturbed models is likely to
produce disturbed behaviors
49
Psychological Dimension
Cognitive Models
O Conscious thought mediates or modifies a
person’s emotional state and/or behavior in
response to a stimulus
O Schemas: Underlying representation of
knowledge and assumptions that guides current
processing of information
50
51
Psychological Dimension
Humanistic Models
O Humanity is basically “good” and trustworthy
O Instead of focusing on mental disorders, the
humanistic approach strives to help people
to achieve self-actualization
O Self-actualization is the inherent tendency to
strive toward realization of one’s full
potential
52
Psychological Dimension
Humanistic Models
O Positive Regards
O warmth, affection, love, and respect
O Conditions of worth
O the conditions that others place upon us
in order to receive their positive regard
53
• Conditional • Unconditional positive
positive regard regard - unconditional
- positive love and acceptance of
regard given an individual by
when another person
providers’
wishes fulfilled
55
Social Dimension
O Emphasis on the social environment
O Social Relational Models
O When relationships are dysfunctional, individuals
may be more prone to mental disturbances
O Example: children from divorced or never-married
families have more psychological problems than
people from always-married families
56
Social Dimension
O Family systems model
O Behavior of one family member affects entire
family system
O Abnormal behavior is a reflection of unhealthy
family dynamics and poor communication
57
58
Social Dimension
O Treatment approaches
O Therapist must focus on the social
environment, not just the individual
O Conjoint family therapy
O Stresses importance of teaching message-
sending and message-receiving skills to
family members
59
Social Dimension
O Treatment approaches
O Couples therapy
O Aimed at helping couples understand and
clarify their communication, needs, roles, and
expectations
O Group therapy
O Group members are strangers initially but
share some common characteristics
O Focus on interrelationships and dynamics of
interaction among members
60
Sociocultural Dimension
O Emphasizes importance of the following
factors in explaining mental disorders
O Gender and gender roles
O Race and ethnicity
O Sexual orientation
O Religious preference
O Socioeconomic status
O Physical disabilities
61
Sociocultural Dimension
O Example 1: Gender roles and eating
disorders
O Over 90% of ED are found in women
62
Multipath Model
63
Concluding Remarks
O There are multiple pathways to and causes
of any single disorder. It is a statistical rarity
to find a disorder due to only one cause
no single is enough: we have to find multipath model
O Explanations of abnormal behavior must
consider biological, psychological, social,
and sociocultural elements
O No one theoretical perspective is adequate
to explain the complexity of mental disorders
64
Required Readings
O Chapter 2
65
ASSESSMENT AND SOSC3900
Abnormal
DIAGNOSIS Psychology
1
OVERVIEW
Standards of assessment
Assessment of psychological disorders
Diagnosis of psychological disorders
2
ASSESSMENT
3
STANDARDS OF ASSESSMENT
e.g. it is consistent 4
STANDARDS OF ASSESSMENT
Reliability
The degree to which a measurement is consistent and yields
the same results under the same circumstances
Reliability
Test-retest reliability
▪ The degree to which a measurement yields the same results when
given to an individual at two different points in time
similar and consistent result, at different time point
but not applicable to unstable variable: e.g. mood
Inter-rater reliability
▪ The degree of consistency of responses when different raters
administer the same measure two or more raters rating same individuals (observable)
same rubrics consistent results
behavioural obsetvation method: won't same rater
Split-half reliability
▪ The degree of consistency between the two scores when a test is
divided into two comparable halves split into two equal halfs
Validity
The extent to which a test measures what it is intended to
measure
Ways to test validity
▪ Convergent validity: Correlation with other well-established
scales correlation of one assessment tool with other well-established (e.g. IQ test)
8
STANDARDS OF ASSESSMENT
Standardization
Standardization is the process by which a certain set of
standards or norms is determined for a technique to make its
use consistent across dif ferent circumstances
▪ Procedures of administration, scoring, and evaluating data
e.g. inkblot test administrator should have
same setting, sequence, procedures, etc. to all
participants
Inkblot Test
psychoanlytic 9
T YPES OF ASSESSMENT
Assessment
Clinical Psychological
Observation Testing
Interview
Psychophyisological
Neuroimaging
Assessment
10
OBSERVATION
11
OBSERVATION
Observation methods
Rating scales
▪ The observer makes judgments that place the person along a
dimension quantify, in number, assign a score
▪ It enables the rater to indicate not only the presence or absence of a
behavior but also its degree can determine degree,
▪ Example: Brief Psychiatric Rating Scale (BPRS) (Overall & Hollister,
1982; Serper et al., 2004)
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14
OBSERVATION
Observation methods
Behavioral coding
systems
▪ To rate the frequency of
specific behavioral events
rate frequency of target behaviour
more problem in
afternoon
should recruit
two or more
observer shd be
blind to hypothesis
15
OBSERVATION
Observation methods
patient a sense of control
Self-observation or self-monitoring
▪ The action by which clients observe and record their own behavior,
thoughts, and feelings can plan the treatment negative changes?
keep track the changes monitor the patient over time
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CLINICAL INTERVIEWS
Face-to-face interaction
▪ Clinician obtains information about client’s situation, personality,
and behavior observe, question and rate
▪ Unstructured interview
▪ Questions are tailored for each client and/or influenced by the habits or
theoretical views of the interviewer theoratical perspective
related questions
▪ Unstructured interviews allow for more exploration but decrease reliability
- reliability, +tailor made questions (more
semi-structured interview: sensitive)
some essential questions 17
but can choose which questions to be asked
CLINICAL INTERVIEWS
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PSYCHOLOGICAL TESTING
19
PSYCHOLOGICAL TESTING
Projective tests
▪ Psychoanalytically based measure that presents ambiguous stimuli
to clients on the assumption that their responses can reveal their
unconscious conflicts
▪ The responses are considered to be “projections” of one’s
unconsciousness and personality
20
PSYCHOLOGICAL TESTING
Rorschach Test
▪ A series of symmetrical inkblots
▪ Test-takers are asked “What might this be?”
21
21
PSYCHOLOGICAL TESTING
Rorschach Test
unconscious desire
red: blood/injury
or high five
22
PSYCHOLOGICAL TESTING
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24
24
25
25
PSYCHOLOGICAL TESTING
Projective Tests
Sentence completion test unconscious desire
▪ I wish
____________________________________________________________
____________________________________________________________
▪ I hate
____________________________________________________________
____________________________________________________________
26
PSYCHOLOGICAL TESTING
roof: overwhelming
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PSYCHOLOGICAL TESTING
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PSYCHOLOGICAL TESTING
Objective tests
▪ Questions are carefully phrased and alternative responses are
specified as choice quantify variable
▪ A predetermined score is assigned to each possible answer
▪ Psychological characteristics can be quantified and compared
+ easy to score the person
e.g. iq score
can compare with others
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PSYCHOLOGICAL TESTING
Objective tests
Minnesota Multiphasic Personality
Inventory (MMPI) find people who are at risk of
mental problem
▪ To evaluate the underlying personality
dimensions among clients in psychological
treatment
▪ The most widely used personality tests for
clinical and forensic assessment and in
psychopathology research
▪ Items were selected based on “empirical
keying” find a large group of psychological health people
find abnormal people
find items that can differentiate people
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PSYCHOLOGICAL TESTING
The MMPI
isolated, lonely
gender disorder
paranoid, e.g. thinking ppl wanna hurt
OCD, anxiety
dillusion, hallucination
The MMPI
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NEUROLOGICAL EXAMINATION
33
NEUROLOGICAL EXAMINATION
less expensive
34
NEUROLOGICAL EXAMINATION
35
NEUROLOGICAL EXAMINATION
decrease in frequency
36
NEUROLOGICAL EXAMINATION
37
NEUROLOGICAL EXAMINATION
have deterioration
38
NEUROLOGICAL EXAMINATION
very expensive
39
NEUROPSYCHOLOGICAL EXAMINATION
40
DIAGNOSIS
41
DIAGNOSTIC & STATISTICAL MANUAL
(DSM-V)
42
DIAGNOSTIC & STATISTICAL MANUAL
(DSM-V)
patient must fulfill some criteria
Diagnostic criteria e.g. 2 criteria
Subtypes sub types of disorder
Specifiersphobia: one source of dear
more severe, patient less responsive
Severity (mild, moderate, severe) general: more severe, more likely have generic
factors (not 100%)
Typical age of onset childhood/adolescent, more accurate, identify unique experience for
treatment plan. More early, more likely generic factors
Predisposing factors causes of disorder, lead to disorder: more accurate diagnosis
Course of the disorder
Prevalence how common in US
Sex ratio Woman likely have depression
Cross-cutting measures PTSD often alcohol
it is useful becoz can see whether patient is responding treatments
43
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44
DIAGNOSIS
Benefits of classification
▪Communication establishment patient
vs. pro
vs. professionals, professionals
45
DIAGNOSIS
Objections to classification
Stigmatization and stereotypes labelling people
IQ vs. not IQ, labelled, but actually are
Differential treatment therefore discrimination same. Labelled IQ have improve
Self-fulfilling prophency Teachers give IQ students have high
cognitive task
▪ Expectations about people that may affect a person's
behavior toward them in a manner that causes those
expectations to be fulfilled patient told that they have one disorder,
make more symptoms to appear
46
REQUIRED READINGS
Ch. 3
47
Anxiety Disorders
1
Video
What is the person afraid of?
overreactive/sensitive in brain
Agoraphobia
7
Diagnostic Criteria
Intense fear of being scrutinized or doing something
embarrassing or humiliating in the presence of
others under the spotlight, thinking others criticize them, judging them
Two subtypes
1. Generalized type
o High levels of anxiety in most social situations
almost all situation
2. Performance Type
Anxiety is tied to specific social situation
specific e.g. when deliver a speech
“Safety behaviors”
any behavior allow the person that they can feel less anxious
drinking alcohol
sitting alone
People with social phobias, on average, have lower
employment rates and lower socioeconomic status
real-life situation
The disorder is chronic and persistent
In a five-year follow-up study, only 40% of patients recovered
patient will persist, despite receive treatment
Etiology of Phobia
Etiology of Phobia
14
Biological Dimension
Genetic predisposition or vulnerability
Two to threefold greater risk of having phobia if a first-
degree relative also has the disorder
generic factor - two to three fold
- concordance rate
Biological Dimension
Biochemical Imbalance
Functional deficit in gamma-aminobutyric acid
(GABA) which ordinarily plays a role in
inhibiting anxiety in stressful situations
normal will produce GABA to overcome anxiety
Biological Dimension
Brain Dysfunction
Exaggerated activation of the fear network (amygdala,
medial prefrontal cortex, and thalamus) in reaction to
phobia-related stimuli dyfunction in fear network
before arrive conscious brain (no danger), amygala already triggered trigger intense reaction
emotionally
information
Etiology of Phobia
18
Psychological Dimension
Psychoanalytic Perspective
Anxiety stems from repressed impulses from the
id repress to unconsciousness (conflicts)
Psychological Dimension
Fear Conditioning
CS
Bird
UCS
Danger
negative reinforcement
Avoid Bird
Etiology of Phobia
20
Psychological Dimension
Observational Learning
We often rely on others’ reaction to judge whether the
situation is safe or not ambiguious stimuli
Observing others behaving fearfully to the stimulus would
make us think that it is dangerous, thus triggering fear in us
observe otuers
Experiment: Children exposed to an anxious-acting parent
reported higher anxiety levels, more anxious thoughts, and a
greater avoidance of the spelling test than children in the
relaxed parent condition observe other feel anxious
Psychological Dimension
Negative information
Receiving negative information may cause an individual to fear an
object or situation
Experiment:
Condition 1: parents receiving negative information about a cuscus
(has long teeth, can jump at your throat, has sharp claws)
Condition 2: parents receiving positive information about a cuscus
(has nice tiny teeth, eats tasty strawberries, like to play with other
animals) cuscus (parents)
Psychological Dimension
Cognitive-Behavioral Perspective
Threat appraisal, cognitive distortions, and
catastrophic thoughts may cause intense fears to
develop over-estimate they threat
Social Dimension
Children raised in social environments with the
characteristics below are more likely to develop
phobia: upbringing experience
Sociocultural Dimension
Females are more likely to have phobias than
males culture/ gender role)
2. No gender difference: just woman are more likely to seek professional help
Treatment of Phobias
25
Biochemical treatments
Antianxiety drugs
Anxiety disorders attributable to functional deficit in GABA
ordinarily playing a role in inhibiting anxiety in stressful
situations increase activity of GABA (not increase GABA)
Biochemical treatments
Selective serotonin reuptake inhibitors (SSRIs)
First choice of drug treatment
50% showed improvement compared with 30% in placebo
Side-effects: headaches, nausea, insomnia much less than anti-anxiety drug
Inhibit reuptake of serotonin (paroxetine)
important to regulate anxiety
Exposure Therapy
Confronting patients with a stimulus that they fear
Gradual exposure
Flooding
Systematic desensitization
Technique in which gradual exposure to an anxiety-producing
stimulus is paired with relaxation to extinguish the response of
anxiety
Treatment of Phobias
30
Modeling Therapy
Through observational learning, patients acquire new skills
and ways of handling their fears and anxieties
“Fearless peer”
Treatment of Phobias
31
Cognitive Restructuring
Aims at changing irrational and unrealistic thoughts
To redirect attention away from themselves
To change self-criticism
To interpret emotional and physical tension as normal
anxiety
Panic Disorder
32
32
Panic Disorder
33
Biological Dimension
Genetic predisposition
Higher concordance rate in monozygotic twins than in
fraternal twins
Heritability rate of 32%
Biochemical Imbalance
Abnormally low levels of GABA
Fewer serotonin receptors
37
Etiology of Panic Disorder
38
Biological Dimension
Brain Dysfunction
Increased activity in the amygdala
38
Etiology of Panic Disorder
39
Psychological Dimension
Psychological Dimension
Interoceptive sensitivity
Hypervigilance
Anxiety Increased bodily
to bodily
increases sensation
sensations
Etiology of Panic Disorders
41
Psychological Dimension
Cognitive Behavioral Perspective
Positive feedback loop: To interpret normal physical
sensations in a catastrophic way
Etiology of Panic Disorders
42
Psychological Dimension
Classical conditioning: interoceptive conditioning
Bodily
Sensations
Panic Attack
Death
Etiology of Panic Disorders
43
Psychological Dimension
Classical conditioning: exteroceptive conditioning
Supermarket
Panic Attack
Death
Etiology of Panic Disorder
44
❑ Biomedical Treatment
– Tricyclic antidepressants (imipramine)
– SSRIs
– Benzodiazepines (Minor tranquilizers)
Side-effects: impair cognitive and motor functioning,
reduce alertness, psychological and physical dependence
Recommended for use in the short term (<2 weeks)
❑ Evidence
– 60% free from panic attacks while on medication
– High relapse rate (20-50%) when medication is
stopped
45
Treatment of Panic Disorders
46
46
Generalized Anxiety Disorder (GAD)
47
Biological Dimension
Genetic predisposition
Family studies
Relatives of probands are 2-3x more likely to have
GAD
Twin studies
Concordance rate of GAD is higher among MZ than
DZ twins
Biochemical imbalance
Abnormalities with GABA receptors
Brain Dysfunction
Overactive fear network
Etiology of GAD
51
Psychological Dimension
Psychoanalytic perspective
GAD results from an unconscious conflict between id impulses
and the superego
Sexual or aggressive impulses that had been either blocked
from expression or punished upon expression lead to free-
floating anxiety
Etiology of GAD
52
Psychological Dimension
Cognitive perspective
Lower threshold for uncertainty
Irrational beliefs about worrying
E.g. “Worry is an effective way to deal with problems”
E.g. “Worry prevents negative outcome from occurring”
Psychological Dimension
Cognitive perspective
Hypersensitivity to threat
Selective attention to threat
Stroop color-naming task
Death Bread
Etiology of GAD
54
Biomedical Treatment
Benzodiazepines (Minor tranquilizers)
Tricyclic antidepressants e.g. imipramine,
venlafaxine
SSRI
Most effective medication
55
Treatment of GAD
56
Cognitive-behavioral therapy
To identify worrisome thought
56
Treatment of GAD
57
58
Treatment of GAD
59
Cognitive-Behavioral Therapy
Coping skills
Designed to reduce arousal e.g. reduce heart rate, muscle tension ,
blood pressure
Beneficial for mental health e.g. reduce anxiety
Required Readings
60
Chapter 5