April 26, 2021

To, To,
Dy. General Manager The Manager – Listing,
Department of Corporate Services, The National Stock Exchange of India Ltd.,
BSE Ltd., Plot No. C/1, G Block,
P. J. Towers, Dalal Street, Bandra Kurla Complex,
Fort, Mumbai – 400 001. Bandra (E), Mumbai – 400 051.

Ref: Scrip Code: 532296 Ref: Scrip Name: GLENMARK

Dear Sir,

Sub: Glenmark’s Ryaltris ® nasal spray now approved in Europe for the first line treatment
of allergic rhinitis in patients over 12 years of age

With reference to the subject mentioned above, kindly find attached media release which is
self-explanatory.

Request you to kindly take the same on record.

Thanking you,

Yours faithfully,
For Glenmark Pharmaceuticals Limited
Digitally signed by
HARISH HARISH VINAYAK KUBER
VINAYAK KUBER Date: 2021.04.26
11:10:28 +05'30'
Harish Kuber
Company Secretary & Compliance Officer

Encl: as above

Glenmark Pharmaceuticals Ltd.

Glenmark House, B D Sawant Marg, Andheri (E), Mumbai 400 099
T: 91 22 4018 9999 F: 91 22 4018 9988 CIN: L24299MH1977PLC019982 W: www.glenmarkpharma.com
Registered office: B/2, Mahalaxmi Chambers, 22 Bhulabhai Desai Road, Mumbai 400 026 E: complianceofficer@glenmarkpharma.com
Press release For immediate distribution

Glenmark’s Ryaltris ® nasal spray now approved in Europe for the first line treatment of
allergic rhinitis in patients over 12 years of age

 The launch will ensure much-needed access to a novel fixed-dose combination nasal spray for this
chronic condition
 This marks Glenmark’s first innovative product approval in the European Union

Mumbai, India; April 26, 2021: Glenmark Pharmaceuticals Limited, a research-led, global integrated
pharmaceutical company, is concluding the final, national phase of its marketing approval application process to
enable launch of its innovative nasal spray in 17 countries in the European Union. Ryaltris® (olopatadine
hydrochloride 665 mcg and mometasone furoate 25 mcg), will shortly be available in Austria, Belgium, Czech
Republic, Germany, Denmark, Spain, Finland, France, Ireland, Italy, The Netherlands, Norway, Poland, Romania,
Slovakia, Sweden, and the UK.

Glenmark will commercialise Ryaltris® on its own in select markets. In some countries such as France, Italy, Spain
and the Balkan region, Menarini Group will lead the commercialisation effort, as part of an exclusive licensing
agreement signed with Glenmark in 2020. Under the terms of the agreement, Glenmark is responsible for the
continued development and regulatory approval of Ryaltris® in these markets, while Menarini will lead the
scientific information and commercialization of Ryaltris®, following regulatory approval. Glenmark has received
an upfront payment and will additionally receive launch & sales based milestone payments from Menarini for
Ryaltris® sales.

Ryaltris®, developed by Glenmark, is a novel fixed-dose combination nasal spray of an anti-histamine and a
steroid, indicated for treatment of symptoms associated with allergic rhinitis (AR) in patients over 12 years of
age. It relieves symptoms of allergic rhinitis, including stuffy nose, runny nose, nasal itching, sneezing, as well as
itchy, red and watery eyes.

Achin Gupta, Executive Vice President, Business Head EMEA-L (Europe, Middle East, Africa, Latam) Glenmark
Pharmaceuticals, said, “Despite many treatments being available for allergic rhinitis, Glenmark is excited to
launch Ryaltris® as the only first line combination inhaler treatment option for patients across Europe.
Upwards of 25% of the population in Europe suffers from the debilitating symptoms of allergic rhinitis, so we
hope that Ryaltris® will bring some of these real benefits – a simple inhaler, offering fast and effective relief.”

Glenmark has also partnered with Hikma Pharmaceuticals PLC and Bausch Health for the commercialisation of
Ryaltris® in the US and Canada respectively. Ryaltris® sales continue to progress well in Australia, after the
successful launch in 2020 by Glenmark’s partner, Seqirus Pty. Ltd. Ryaltris® was also recently launched in South
Africa, Ukraine and Uzbekistan. So far, Glenmark has received approval for Ryaltris® in Australia, South Korea,
Cambodia, Ukraine, Uzbekistan, Namibia, Russia, South Africa, and Ecuador. Ryaltris® is currently under
 regulatory review in Canada, Brazil, Malaysia, Saudi Arabia and several other markets. Glenmark’s partner in
China, Grand Pharmaceutical (China) Co. Ltd., plans to submit an IND in this financial year.

—End—

About Glenmark Pharmaceuticals Ltd

Glenmark Pharmaceuticals Ltd. (GPL) is a global research-led pharmaceutical company with presence across
Generics, Specialty and OTC business with operations in over 50 countries. Glenmark’s key therapy focus areas
globally are respiratory, dermatology and oncology. It is ranked among the top 80 Pharma & Biotech companies of
the world in terms of revenue (SCRIP 100 Rankings published in the year 2019). The company has been listed in the
Dow Jones Sustainability Index (DJSI), under the category of emerging markets for the third consecutive year in a
row. DJSI is one of the world’s most respected and widely accepted sustainability benchmarks globally with only the
top ranked companies in terms of Corporate Sustainability within each industry are featured in the index. For more
information, visit www.glenmarkpharma.com

For more information:

Glenmark Media Contacts

Udaykumar Murthy

Senior Manager, Corporate Communications

+91 9960377617

corpcomm@glenmarkpharma.com