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Junqueira Lymphoid Organs (Dragged)
Junqueira Lymphoid Organs (Dragged)
MS
MC MC
MS MS
MC
a b
(a) The medulla of a lymph node consists mainly of the medullary cytoplasm than lymphocytes. Efferent lymph is rich in newly syn-
sinuses (MS) separated by intervening medullary cords (MC). Lym- thesized antibodies. A medullary sinus (MS) with a meshwork of
phocytes and plasma are abundant and predominate in number eosinophilic processes from surrounding reticular cells is also seen.
over other cell types. A blood vessel within a medullary cord is also (X400; H&E)
seen. (X200; H&E) (Used with permission from Dr Paulo A. Abrahamsohn, Institute of Bio-
(b) Higher magnification of a medullary cord (MC) shows plasma medical Sciences, University of São Paulo, Brazil.)
cells (arrows) with spherical, eccentric nuclei and much more
C
The capsule (C) of the spleen connects to trabeculae (T) extending
into the pulp-like interior of the organ. The red pulp (R) occupies
most of the parenchyma, with white pulp (W) restricted to smaller
T areas, mainly around the central arterioles. Names of these splenic
W areas refer to their color in the fresh state: red pulp is filled with
blood cells of all types, located both in cords and sinuses; white pulp
is lymphoid tissue. Large blood vessels and lymphatics enter and
leave the spleen at a hilum. (X20; Picro-Sirius-hematoxylin)
R R
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