DRUG ACTIONS SIDE EFFECTS ADVERSE INDICATIONS CONTRAINDICATIO NURSING

NAME EFFECTS NS RESPONSIBILITIE

S
GENERIC Physiologic  Nausea/ Potentially  To induce  Hypersensitivity  Before giving
NAME: Mechanism: Vomiting Fatal: preoperativ to midazolam,
MIDAZOLAM Post-operative  Rash Life- e sedation benzodiazepines. determine
amnesia  Restlessness threatening or amnesia, whether
BRAND Short-term  Slow/Irregular breathing to control  Chronic patient
NAME: sedation heart beat problems preoperativ respiratory consumes
Hypnovel,  Agitation (shallow, e anxiety insufficiency. alcohol or
Midazolam Pharmacologi  Uncontrollable slowed, or takes anti-
Alphapharm, c Mechanism: shaking of a temporarily  Aids in the  Acute angle- hypertensive,
Midazolam Effects may be part of the stopped induction of closure antibiotics, or
DBL, mediated by body breathing) anesthesia glaucoma; protease
Midazolam GABA, an and as part alcohol inhibitors.
Pfizer, inhibitory CV: Cardiac of balanced intoxication;

Midazolam neurotransmitt arrest, anesthesia. coma;  Assess level of
Sandoz er hypotension, hypersensitivity consciousness
Acts at many nodal  Preprocedur to midazolam, frequently
DOSAGE: levels of the rhythm, PVCs, al sedation other because the
inject 1 mg CNS to produce tachycardia benzodiazepines, range between
for 30 generalized or their sedation and
seconds CNS depression SKIN: components; unconsciousne
Pruritus, rash, shock ss or
FREQUENC urticarial disorientation
Y: STAT is narrow with
CNS: midazolam.
Route: IV Agitation,
delirium, or  Monitor Blood
dreaming Pressure,
during respiration and
emergence pulse
from continuously
anesthesia; during IV
anxiety; administration.
ataxia; chills; Oxygen and
combativenes resuscitative
s; confusion; equipment
dizziness; should be
drowsiness; immediately
euphoria; available.
excessive
sedation  Assess level of
sedation and
level of
consciousness
throughout
and 2-6 hours
following
administration.

 If hypotension
occurs,
treatment
includes IV
fluids,
repositioning
and
vasopressors.

 The effects of
midazolam can
be reversed
with flumazenil
(Romazicon).