PATHOPHYSIOLOGY

MODIFIABLE NON-MODIFIABLE RISK FACTORS

 Hyperlipidemia  AGE-67-year-old
 Hypertensive drugs  SEX-Male
 Acute renal failure  Overweight

Severe uncontrolled hypertension

Blood flow decreases

temporarily
Auto regulation failure

resistance Lead to decrease in blood

flow and an increase in
vascular resistance

Vasoconstriction

Endothelial injury Ischemia Decrease alertness

activated neutrophils produce heart muscles become

endothelial cell damage damaged showed his optic nerve
sheath to be 5.3 mm in
diameter

 Proteinuria
 creatinine of cardiac troponin I
1.4 mg/dL
 BUN of 30 mg/ dL.  elevated at 0.5 mg/mL

Myocardial ischemia Hypertensive encephalopathy

Acute kidney failure

Target organ
damage

HYPERTENSIVE
CRISIS