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Motecalay Rags of Inheritance Jo Amis Chapter Wot will dis cuss + - Stuchee oft OMA = DNA Reelicedion - Premehiono? DNA Lom DNA _ — Transcription - DNAa— enfA = Trecnglahion -— DNA — RNA —> Pettia = Hang xegrukshion . TRANS ow. & a homet Frew oF intemah'on_ fom On to protein is cone = — Prepoged by F Cwcr. . (DNA > QN#———> Protein Replica o 5 Tens Tansleon i Q [Dp LOSCAPhO Ng Leanslahie o otein \J Swe ~ ——Repitarren Peto —_Bepicn me i The MSCri PH on # Rev phon d's. oi Hmoe - io ROUS-S on i Tenn * RNA Replication boy Ribe2yme io many VNUSE 1 dD. ~—*_Priems__¢ser_not -feitouas _Cermbreet Ogg ma. _ i, he have te est Under Stand re Nucheic AG: 2 Me icChex _diSCovered Nucleic Term Nuctote Acid =By Aman. —> Nucleic Acids ave Poy Meret Nucleoti ——— Wy uc teotdg — No=-Rase ae ine ta nine Uwacit be Pyrimidine ao 2 P. ning, Guanine ery Davin — ariemiine = Yeacie £25 Wy Pesent 9,84 —— ne eid A202 An Pyrvionidi lmidazofe — N ho i aa as ae Ry ed $ Cece A Qa, 37 3p Wann Guaame roxine Rog SO-Weninepurine) (3 Amino i | Purcimidine with one ing Cee | z Nh Nh o ae eae eS =f ‘ ogy, ___ Chey oN she ra f hu at {! ng i nw Ni eae O18! Ribose De oxy sibose Cin evf) __ cin ONA) PhosPhabt- _- Ha Pog, Pela sap iadertat oO see! 1 an On Pe OW - oh of : eee = - o_bena withA i" Carbon of Pergo __ Pemte. ucheoSi Gly comielic. ____Uinxate ike Adenofine or O¢ oxy adensgine, N-Giyro gare Gakay oa ute & 5;-€,-C# Ng) o Np -BaX a : T,c,9 CN3) i ae - PASSPhediditer] _ (P) oD {re ler Bona \ tnd @a G | SS —— 9g > Btypes Of Nuc Cotdeg fond ina Animal coti ane Plant Gy 2 G4 oNa 9 4 QNA O.NA RNA A+ —Decnysr hase +P A+ Rikose eee Gs a — +9 Gr ep if acasaas fer ae C+ -v— +P Cie fe Ste U+ —m— +P 2 Base Sugar Necleomiee _ PhegPicte er Bdouine _ Ribose Aaomeein ti _ Aden’ vie Deotaunbine Path Dena Guanine “Bibese _Gwenogine — tharphate Guany bic Aad Guanine Deaytinace De orygvanoine — Prsephats— Et Cag “hic Ace 4% Come Ore Single Noe Wotde ice ATP. Ade, Ame - hove 1 +2 3 Phosphate Vite A oO eee renee yaa _ Aig ia Raa Uwaa't (ud is Pound in pla@ 2° Thymine CS= Je iny| Uracit ,anohre, namecl Thy ting oo (Cin: Grd_Thywine and Gracies} = > DNA_as_an acdic Svbstante Present in nucd _____Was First identified by Fi meiscea Cge He Hamed it as” NUCWwin” James WarSon ana Francs Cick Ci9S3) = Rased m_X=ray AiTferachondabe Produced Maurice wilkins‘ana Rosatindg Prankhin, _____PropoSea Double Helix Modet Far Stu neo? DNAS Grok Mobed Pri2e in 1962 (watgen, Crick and Wilkis Silent Fvatwes of D ef Double Helix St. of ONY: | TENS made up of. ¢ Cain ax q tne Sy - Phose ccs | nd tne Ba PvoleGe ingidg . The juno Chains have ankarall ae falas ih poate __|_Means if one Caaio has Polarity. 2 Sher has @'—»> 5 . > bases j 9 Strands Cet Paired Tyre! oo H-Qama) feming Base Pa “CAdatne form Awe hy deagen binds Ieee ity Trymine from _oppofite © @ vig Versa) G=ec CGuanine banded with S trace Hy dwoGen bonds Ad Vice Vesa = Se nbscaye fui bi quith Py rien dine Ni bate ee —. =This_g cherades approxi whey. Un neon dis 2 | between “Awe Shunde of Kalix. He = The tao Cauiing are Coile 10.9 Ght handed Fashion _- The pittn of helix iS 24am Clam: 1o3m)_ &} ~ Mere ave gene “10 be (Gate pairs) 19 eas tum Cre generally. _____ Seine distime plo a bia a helix i ine tie O34 nm. = The plane one base paix Stuces over the otner jo double Helix Tris in addition of te te Bonds. ConFerc 7 of Heli 5 = : wise i & i w 7 7 oe z ==; @ =o 6 a, a EHS Bo ou Qi _ Gignceergzy Dovste St-umaas PoyNoehes Cain. Pagens 38)" classmate. [| Spaoentaa? K Because ef twig tre tre Shootin of ON cus PrddoG A (ngllnho idonkeel to nao | DNA Mote cule . gen ehic IN ica eV Cleg I-A =T— LA= + i GH ec — Lose I-T=a =A Rat 4 cr S75 a l Cea FczcqH Fe I Parenter Davgicer DNA ING / 2 Oo 3 —Qvesion based om. Charge Pf's Rube _ On tas DnB ne bases af Masine Gna gti Caw Pot Gent Tren totul Number df ny bages in Dutt one 2 = = 00 = j Bco aw {+ Gz Lyte ] @. Ta g_DS PNA Adenine istSl Tren what is we PerGmr of Guanine -? Bee Pre Gr Roe ye eel po- @R= 62, = Q-c & G=ait G c: ah A-T Tyee DNA sip Eukorget c Ct) A+T > QtC = AT Wee DNA rio = Od 2 Pons = 4:6 X08 Bake pesixy ~ 6-6 x 109 Base Pais. 10 _ Packaging of ONA helix . _NockeoSeme oe modal => Tre _overcige distem@ bebseen hoo Base €id5acenn) a is 0-24 om. Co-ay xi@mibe oy 2-4 a2) > TP Lengtnok Dra oonte helix ina stypi cat = Mammatian Cay js Caltulated By tou \4i Ply jag— [era nummer of bp itn distune bebaeed o - tV0 Cmsecutve bp ie ef G6 x 10% bp x 024 x lo? m/ pp = 2.2 meter => Dimertion of typical oucteys is _107o m —> S&S how fe 22am Maia DNA Ns Packaged to Be Sma noctws of fo“ 6 m Smengion. 2 _4.- A E-coli DNAs \36@05" aa i Cutcutete —tee_numngr sf base Pair: jo E-oot 2 fas G+6 xX 0% bp in @- Coli : is j= _fececging of pre “10 Pro kohmstes: —__T. Pro. Ss Nike E- Cot not have eI) ____ do fine oA DNQ_is not SCattrred Proteins like Polyqmine ee ee -Nvcheofe ma \Fobgewed by-Olin's , ‘ TEM Noclgobmae by— Proud “4 — Mucho Soma Modo by- Koen berg & Thomag tt - — Packaging of DNA 19 Eukowsestes: gels —=la_eukaryotes DNA Packaging 1s eae Comphe : > Mor ts oo set of postive! _ basic _p ssasbesasdsssail | Subs Histone itn in Angi ine _Q Ly Sine Agnine aude ; => A protein acuire tne Cnerge do pending ve ON Fina ee ino Acid SeSdues witn Charyed Gide Cnaiias Win nuchoogmeg is Called at Linker ONA tinker DNA Ys oftate iSteme Pvfeig = Gare 4 nr Seecies te SPeies — --=HuclesSame Chain aves a. beads _on String cppeaam 7: Under Cle Aron _mitwa8cope —___ = Nvclpodemes Gastutes the 32 \e oe Se > The Pacseaging o) Ouivamatinlahs hiy\woy devet _ oequi aes Addi Hmal Set oh pvoteias hae est Case. a _ We —Cohechvely attest d of - Non histone Chromoimul ae GN Fn astisye __ | otras: Raa Histone Chosmafm at Pteins Cae ot Dips Oo Stuctrrar ft He @vsteiq ) ace Eumctiong! Ne protein ¢x. Diver Plymewase, . ae RNA Pay Marase eee LHe es | Se a ice) ny Catania Chromatia Goer levity fpssci _ | Gee { Called of @UChvmautin Whi ayers Corie Geinesiceliy More cicive . = Tre _Chvenastin thet is_Srere_donasly patked ma Stains dark vt Cwled 03 He tevschvomatin_ GdhiCk chrepns Card Pima Y Chreormain if © Sven oid vee go yee er The Ser Sesh sn Fer Denetic mules: DNAS G is Genehic Mabe od achat oo pit wemo&ime? loccoted ia tne nucleus of Mei Cong + Brit Bui tno Quettio of cote What tia Motecule Was —cheiny tre, genetic omefesial had not been Ahsw or = Let eXP@iomentr [Yoved traf ONA js tre Geen Oh'c Material. _____ 3 Tyemsfermetin exeenment on Backea —_____@) ee ___@) Toans plete cSieeeeaeinsn oe se pee Ee C1928) eles In _eHedsti itning appear Of gemetic onoteriat if — = He experimented on Sve ptececcus Pneumoniae peau tacking tenon) esd py VC MN Coke Cock pi! ML G_1936Ge A wity A Ferm — Nore died US Sfpeig — oseti ia fm i@—= Mig die i R-Spuig —> Ime lami@ —> Mig Live et AY. — Goi bhity silled tre Bacteria sy Heating Prem i S- Shain => In deced jo ss SM) Ge Live Cie ak tei ed 2 nn. a — When he indeed @ Minture of Nab killed Ssbu | ana_live R Stain Qacheria the mi@ died S-Shuig 7 ee Cea ki Ned ) = inked —> Mic Died. + into mic uve Rohain a = hte Conctuded trot tro R-Sbain Bacteria had Smehow bem heans-Penemed by Tha ect killed @& S- Shuin Qacteia ue 7 ing @aaciele” transfered fom iNed_S=Spain, had enabled tre —__&-Struio te Syntregise G_ Smooth Polysaccharide — Cook ana beCome Wiley tne Genmstic. — This Mmvst be dwe

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