Maintenance Manual: C2000 1/2/4 Semi Automatic Coagulation Analyzers

Maintenance Manual for C2000 Series Semi-Automatic Coagulation Analyzers

C2000‐1/2/4
Semi‐Automatic Coagulation
Analyzers

Maintenance
Manual
Beijing Precil Instrument Co., Ltd.

Preface
Intellectual Property
Beijing Precil Instrument Co., Ltd. (Precil for short) owns the copyright of this
non‐public manual and has the rights to keep this manual confidential. This manual
provides reference only for maintaining Precil products.

Precil owns all intellectual property rights (including the copyright) of this manual.
It is prohibited to use, disclose, or spread the information in this manual in any
manner without the prior written approval of Precil. It is prohibited to photograph,
copy, print, or translate (or conduct any other similar activities) the information in
this manual in any manner without the prior written approval of Precil.

Precil reserves the right of final interpretation for this manual.
Precil reserves the right to modify the content in this manual without prior notice.
Precil reserves the right to modify relevant technologies without prior notice.
Precil reserves the right to modify relevant product specifications without prior notice.

Disclaimer
Precil is not liable for this manual in any manner, including (but not limited to) the
warranty of merchantability or fitness implied in this manual for any particular purpose.

Precil is responsible for the safety, reliability, and performance of this product,
only if:
 all installation operations, expansions, changes, modifications, and repairs of this
product are conducted by Precil authorized personnel;
 the relevant electrical devices comply with national standards;
 the product is used in accordance with instructions.

Precil is not responsible for safety, reliability, and performance of this product, if:
 components of this product are disassembled, stretched, or re‐commissioned;
the product is not used in accordance with instructions.

● Application Scope
This manual applies to the product maintenance conducted by Precil customer
service engineers or Precil authorized personnel.

● Use of This Manual
Content in the preface is informative. And content of Warnings must be observed
during operations. Ignorance of the precautions or misoperation may cause failures
of the product or even endanger personal safety.

This manual contains four chapters, which are described as follows:
Chapter 1: Structure and Function. This chapter describes the instrument structure.
Chapter 2: Troubleshooting. This chapter describes common troubleshooting methods.
Chapter 3: Commissioning. This chapter describes common commissioning methods
and relevant precautions.
Chapter 4: Maintenance Diagrams. This chapter describes the system principle
diagram and cable layout diagram. These diagrams may not cover all
details about the instrument but provide reference for maintenance
engineers who are familiar with the instrument.

● Warnings

Warning 1
Before maintenance, carefully read the operation and safety instructions in this
manual to ensure proper operations.

Warning 2
When the operating environment of the instrument does not comply with the
Operation Manual for C2000 Series Semi‐Automatic Coagulation Analyzers, the
instrument may not operate properly or even become faulty.

Warning 3
Sudden power failure:
When a transient voltage drop occurs due to power failures or lightning strikes,
the instrument may become faulty. In addition, the basic software, application
software, data, as well as memory data and software may be damaged.

● Commitment
Warranty Period:
Precil provides a one‐year warranty and lifelong maintenance for the product.
Maintenance services and accessories are free of charge during the warranty period.
After the warranty period expires, customers are charged for replaced accessories
and maintenance services.
Warranty Particulars:
During the warranty period, Precil provides free‐of‐charge maintenance against
faults relevant to the product design and manufacturing. Maintenance methods are
determined by the manufacturer based on the faults.
Exemptions:
(1) The operating environment does not meet the requirements of this manual.
(2) The customer misuses, misoperates, or operates the product in a rough
manner.
(3) The product is not moved, transported, or installed in accordance with the
procedures and methods recognized by the manufacturer.
(4) The product is disassembled without permission.
(5) The product is damaged in natural disasters (including fire accidents,
earthquakes, floods, wind disasters, and thunderstorms), terrorist activities,
wars, or other acts of God.
(6) The customer uses parts that are not provided by the manufacturer.
(7) Consumable parts become faulty, or the service life of the components
expires.
(8) The customer does not maintain the product in accordance with the
manufacturer's requirements.
(9) The customer buys a second‐hand product without contacting the
manufacturer.
(10) The system crashes or the hardware is damaged due to computer viruses.

● After‐Sales Service
Service Particulars:
Installation and commissioning:
Precil customer service department and local dealers
Application training:
Precil customer service department and local dealers, providing free‐of‐charge
training on installation and on‐site applications
Maintenance:
Supply of accessories:
Direct service
Precil customer service engineers provide direct services for customers.

● Contact Information
Address: East 2F, Building No. 5, Qunying Technology and Science Park, No. 8
Chuangye Road, Shangdi IT Industry Base, Haidian District, Beijing, China
Telephone: +86‐10‐62987758 / 62963063 / 62971023 / 62964796
Postcode: 100085
Fax: +86‐10‐62987761
Customer Service Department: +86‐10‐62963237 extension 21
Email: plslhy@163.com
Website: www.precil.com.cn

Contents
Chapter 1 Structure and Function.......................................................................... 1
1.1 Structure ...............................................................................................................1
1.1.1 Structural Diagram of C2000‐1 ..........................................................................1
1.2 Parts and Functions............................................................................................ 10
1.2.1 Power Switch Board........................................................................................ 10
1.2.2 Heating Board ................................................................................................. 11
1.2.3 LCD .................................................................................................................. 13
1.2.4 Main Board...................................................................................................... 14
1.2.5 Network Access Board .................................................................................... 15
1.2.6 Test Strip ......................................................................................................... 16
1.2.7 Mixer Motor.................................................................................................... 16
Chapter 2 Troubleshooting.................................................................................. 17
Chapter 3 Commissioning.................................................................................... 19
3.1 Checks to Be Performed Before Commissioning and Maintenance.................. 19
3.1.1 Check whether all parts are installed properly and whether lines are
intact with good connectivity. ........................................................................ 19
3.1.2 Check whether the pre‐warming hole and test hole are blocked or
damaged. ........................................................................................................ 19
3.1.3 Check whether the power voltage output is normal...................................... 19
3.2 Circuit Board Installation ................................................................................... 19
3.2.1 Add loads on the power supply to enable discharge before
the installation. ............................................................................................... 19
3.2.2 Install circuit boards in the specified positions and connect
the corresponding signal cables. .................................................................... 19
3.3 Self‐Check and Version Check............................................................................ 19
3.4 Temperature Calibration.................................................................................... 20
3.5 Channel Calibration............................................................................................ 21
Chapter 4 Maintenance Diagrams ....................................................................... 22
4.1 System Principle Diagram .................................................................................. 22
4.2 Cable Layout Diagrams ...................................................................................... 23
4.2.1 Cable Layout Diagram of C2000‐1 .................................................................. 23

Chapter 1 Structure and Function
1.1 Structure
1.1.1 Structural Diagram of C2000‐1
Pipette
Ball dispenser
Display
Membrane keypad
Reagent pre‐warming area
Sample
Top case pre‐warming
area
Test area
Bottom case
Figure 1.1 Front view of C2000‐1

External printer
connector
Pipette connector

Figure 1.2 Rear view of C2000‐1
Heating
board
LCD
Main
board
Figure 1.3 Internal components in the top case of C2000‐1

Power switch board
Figure 1.4 Internal components in the bottom case of C2000‐1

Position of the
ball dispenser
Built‐in micro printer
Reagent
pre‐warming area
Test area
Sample
pre‐warming area
LCD
Membrane
keypad
Top case Bottom case


Pipette connector
Heating board Printer
drive board
Mixer motor
drive board
Main
LCD
Top case
Figure 1.7 Components in the top case of C2000‐2

Network
access board
Power
switch board
Bottom case
Figure 1.8 Components in the bottom case of C2000‐2

Position of the
ball dispenser
Built‐in micro printer
Position of the pipette
Top case LCD
Reagent pre‐warming
position
Test area
Pre‐warming area
Membrane
keypad

Mixer motor
drive board
Heating Printer drive board
board (small)
LCD
Pipette connector
Heating
board (large)
Test strip
Main board
Top case
Figure 1.11 Components in the top case of C2000‐4

Power switch board
Figure 1.12 Components in the bottom case of C2000‐4

1.2 Parts and Functions
1.2.1 Power Switch Board
24 V/12 V power switch board: The 24 V power is supplied to the heating board and main
board. The 12 V power is supplied to the test head.

Figure 1.13 24 V/12 V power switch board

1.2.2 Heating Board
The heating board provides precise temperature control to ensure the accuracy of test data.

Figure 1.14 Heating board of C2000‐1
Figure 1.15 Heating board of C2000‐2

Figure 1.16 Heating board (large) of C2000‐4

Figure 1.17 Heating board (small) of C2000‐4

1.2.3 LCD
Figure 1.18 LCD of C2000‐2
Figure 1.19 LCD of C2000‐4

1.2.4 Main Board
The main board consists of the power supply, CPU, and test parts.

Figure 1.20 Main board of C2000‐1




1.2.5 Network Access Board
The network access board exchanges data between the instrument and the computer.

Figure 1.23 Network access board

1.2.6 Test Strip
The test strip consists of four groups of coils in two pairs, including two groups of drive
coils and two groups of test coils.

Figure 1.24 Test strip
1.2.7 Mixer Motor
C2000‐2 and C2000‐4 provide reagent mixing positions. Figure 1.25 shows the DC motor
and control board components, which are driven by a 5 V DC power supply.

Figure 1.25 Mixer motor assembly

Chapter 2 Troubleshooting
Corrective
No. Fault Possible Cause Check
Action
Some of the four Check the operation procedure Standardize
a. Operation problem
coagulation according to the instructions. operations.
1
parameters are Replace the
b. Reagent problem Check the reagent quality.
abnormal. reagent.
The test results
are inconsistent, Improve the
Improve the precision of
2 and precision Sample loading problem operation
sample loading.
does not meet proficiency.
requirements.
The FIB curve a. Inaccurate dilution of
Create a new
and R value do calibration plasma Check whether the R value is less
3 standard
not meet b. Improper operations and than 0.98.
curve.
requirements. inaccurate sample loading
a. The room temperature is
displayed on the instrument,
The temperature
indicating no heating. Check the power supply or Replace the
4 display is
b. The temperature displayed triode (540). faulty part.
abnormal.
on the instrument is higher
than 40°C.
The temperature
display is normal, Adjust the
The temperature coefficient is Check the temperature according
5 but the actual temperature
not set properly. to the temperature indicator.
temperature is coefficient.
higher than 37°C.
The membrane keypad
The keys do not Replace the
6 connection is poor or the keys
respond. membrane.
are faulty.
The pipette does Check whether the connection
Rectify the
7 not respond when of the pipette is normal and
open circuits.
you press it. whether open circuits occur.
The mixer motor makes a loud Adjust the
There is a loud
noise. The position of the mixer position of
8 noise during
motor magnet support is the mixing
reagent mixing.
incorrect. rod.
The power cable is not
The system does connected properly, or the fuse
Check whether the voltage at the Replace the
9 not respond after or rectifier bridge is burned out.
GP point is 5 V. faulty part.
power‐on. The power chip (2596) is
burned out.
The measured FIB Create a new
The standard curve is
10 values are too standard
abnormal.
high or too low. curve.
No steel ball is Use the
a. The cup and steel ball are not Check whether the "NO BALL"
11 detected. original steel
manufactured by Precil. prompt is displayed.
(NO BALL) ball and cup.
Check whether the amplitude
b. The amplitude of the steel becomes smaller as the R15 (10 Ω) Replace the
ball is too small or too large. increases and becomes larger as resistor.
the R15 (10 Ω) decreases.

Corrective
No. Fault Possible Cause Check
Action
The null value does not meet
requirements: 1. short circuit of the
test strip (the null value is about Replace the
400 or 500); 2. open circuit of the test strip or
test strip (the null value is 0); capacitor.
3. breakdown or capacity decrease
of the 12 V filter capacitor (C5).
The plasma calibration is incorrect.
Test the
The calibration value is more than or
capacitance
less than 20 times of the null value.
of the
c. Calibration problem Check the capacitors corresponding
channels by
to channels 1, 2, 3, and 4. Channels
using a
1, 2, 4, and 5 correspond to
capacitance
capacitors C52/C53, C54/C55,
meter and
C56/C57, and C58/C59 respectively.
replace the
If the calibration value is more than
capacitors
20 times of the null value, use
based on the
capacitors with a smaller capacity. If
plasma
the calibration value is less than 20
calibration
times of the null value, use
value.
capacitors with a larger capacity.
Check the resistance of the test
The plasma
strip (50 Ω for two groups of coils, Replace the
solidifies, and the a. The test strip is faulty.
and 180 Ω for another two groups faulty part.
12 ball stops moving,
of coils).
but the counting
Check the 8th pin of U10 Replace the
continues. b. No –5 V voltage is available.
(7660 chip). faulty part.

Chapter 3 Commissioning
This chapter describes the methods for commissioning the instrument, including the
pre‐commissioning checks, circuit board installation, dual needle installation, pipeline connection,
dual needle and mechanical gripper coordinates, magnetic ball channel calibration, luminous flux
values, and other system parameters.
Maintenance engineers must learn the following precautions before commissioning:
(1) Disconnect the power supply before replacing a component or inserting/removing
a conductor.
(2) Do not pull or twist the cable when removing a plug.
(3) Prepare a multimeter and other common tools.
3.1 Checks to Be Performed Before Commissioning and Maintenance
3.1.1 Check whether all parts are installed properly and whether lines are intact with good
connectivity.
3.1.2 Check whether the pre‐warming hole and test hole are blocked or damaged.
3.1.3 Check whether the power voltage output is normal.
3.2 Circuit Board Installation
3.2.1 Add loads on the power supply to enable discharge before the installation.
3.2.2 Install circuit boards in the specified positions and connect the corresponding signal
cables.
3.3 Self‐Check and Version Check
Power on the instrument. The self‐check menu is displayed on the instrument, as shown in
Figure 3.1. Check whether the version is the latest.
Four‐channel coagulation analyzer V x.x
Beijing Precil Instrument Co., Ltd.
Precil
TEL: (010) 62987758
Figure 3.1 Start menu of C2000‐4

Menu Description:
Precil: English name of the manufacturer
TEL: after‐sales service telephone of the manufacturer
V x.x: version of the instrument

Main menu: After the start menu is displayed, the instrument automatically enters the main
menu, as shown in Figure 3.2.
‐ Precil C2000 ‐ T=x.xx

Test Calibration Parameter System
Figure 3.2 Main menu of C2000‐4

3.4 Temperature Calibration
The instrument temperature is detected and controlled by the built‐in temperature sensor
and may be inaccurate. Therefore, it must be calibrated by using a standard thermometer certified
by the national metrology department.
(1) After the instrument starts, wait until the temperature displayed on the instrument reaches
37°C. Add 150 µl distilled water to a test cup, place the test cup into any pre‐warming hole,
insert a standard thermometer certified by the national metrology department into the test
cup, wait 3 to 5 minutes, and read the temperature on the standard thermometer.
(2) Temperature Calibration Setup
On the main menu, move the cursor by using the left and right arrow keys. Select System and
press OK. The system menu is displayed, as shown in Figure 3.3.

System Parameter T=x.xx
Printer=xxx Buzzer=xxx Mixer=xx
Temperature Coefficient 1=x.xxx Temperature Coefficient 2=x.xxx
xxxx xx‐xx xx:xx:xx
Figure 3.3 System menu of C2000‐4

Menu Description:
Printer=xxx: Four options are available for this parameter.
=On1: instant print; =Ons: batch print; =Prt: to start batch print; =Off: to stop print.
Buzzer=xxx: Three options are available for this parameter.
=All: to enable the buzzer during sample loading and pre‐warming; =Tst: to
enable the buzzer only during sample loading; =Off: to disable the buzzer.
Mixer=xxx: Two options are available for this parameter.
=On: to enable the mixer switch; =Off: to disable the mixer switch.
Temperature Coefficient 1 and Temperature Coefficient 2: Temperature coefficients of
the test area and the reagent pre‐warming area.
Temperature Coefficient 1: Temperature coefficient of the test area; Temperature
Coefficient 2: temperature coefficient of the reagent pre‐warming area.
xxxx xx‐xx xx:xx:xx: Current time in the format yyyy mm‐dd hh:mm:ss. You can set
the time as required.
T=xx.x: Current temperature displayed on the instrument.
① You can set the printer, buzzer, and time as required.
② Temperature coefficient: The instrument displays the temperature of the test area.
The temperature is commissioned at room temperature before delivery. However,
the temperature sensor is highly sensitive to the ambient temperature. If the
deviation of the instrument temperature exceeds ±0.5°C during installation, you can
adjust the temperature coefficient. Adjustment method: Move the cursor to
Temperature Coefficient and press OK. Adjust the temperature coefficient by using
the left and right arrow keys, press OK, and exit the menu. The setting is saved.
Adjustment rule: The temperature displayed on the instrument changes by 0.4°C
when the temperature coefficient changes by 0.01. Example: The temperature
coefficient is 1.000, the actual temperature is 36.4°C, and the temperature displayed
on the instrument is 37.0°C. In this case, you can adjust the temperature coefficient
to 0.990. The temperature coefficient of the test head is set by the manufacturer
before delivery. If the temperature accuracy meets the requirement, do not modify
the temperature coefficient.

3.5 Channel Calibration
(1) Null test: Set the test channel to null and temperature to 37°C. Enter the system menu, set
the year to 88, and save the setting. Enter the test menu, select any test item, and enable the
test item for all test channels. The instrument counts and obtains the calibration data, which
should be less than 50.
(2) Media test: Add 150 µl PVP (or plasma in a hospital) to a test cup with a steel ball, pre‐warm it
for 3 minutes, place it in a test channel, observe the movement of the steel ball, and enable
tests for all test channels. The instrument counts and obtains the calibration data, which
ranges from 100 to 1023 and is equal to or greater than 10 times the corresponding null data.
When the values in the null test and media test meet requirements, enter the system menu
and set the system time to the current time. The calibration is completed.

Chapter 4 Maintenance Diagrams
4.1 System Principle Diagram
The following figure shows the system principle diagram of C2000‐4. The number of channels
on C2000‐1 and C2000‐2 is different from that on C2000‐4.

4.2 Cable Layout Diagrams
4.2.1 Cable Layout Diagram of C2000‐1
board
Heating
Pipette base
connector
Keypad
Printer
LCD
Power switch board
Main board
Cable layout diagram of
Fuse
April 14, 2010
C2000‐1
resistor
Voltage‐dependent

Pipette base
Keypad C2000‐2
April 14, 2010
Mixer motor
Network board
access board
Printer board
(small)
Fuse
LCD
Main board
Main printer
board
Cable Layout Diagram of C2000‐2

Voltage‐dependent
Heating
resistor
board
Printer
connector
Power switch board
4.2.2

Keypad Pipette base
C2000‐4
April 14, 2010
Mixer motor
Network board
access board
Printer board
(small)
Fuse
LCD Main board
Main printer
board
Cable Layout Diagram of C2000‐4

Heating
Voltage‐dependent
board (large) resistor
Printer
connector
Power switch board
Heating board
4.2.3
(small)

Maintenance Manual: C2000 1/2/4 Semi Automatic Coagulation Analyzers

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