form of Stress: SpringerLink 2. Cavicchioli, R. 2002. Extremophiles and The Search for Extraterrestrial Life. Astrobiol. 2 (3): 281-292. 3. Dalmaso, G.Z.L., Ferreira, D. and Vermelho, A.B. 2015. Review: Marine Extremophiles: A Source of Hydrolases for Biotechnological Applications. Mar. Drugs. 13: 1925-1965. 4. Widhiastuty, M.P., Febriani, Yohandini, H., Moeis, M.R., Madayanti, F., and Akhmaloka. 2009. Characterization and Identification of Thermostable Alkaline Lipase producing Bacteria From Hot Spring Around West Java, Journal of Pure and Applied Microbiology, 3: (1) 27-40. 5. Mesbah, N.M., and Wiegel, J., 2012.Life Under Multiple Extreme Conditions : Diversity andPhysiology of The Halophilic Alkalithermophiles, Applied and Environmental Microbiology, 78 (12): 4074-4082. 6. Ammor, M. S., Rachman, C., Chailou, S., Prevost, H., Xavier, D and Zagorec, M. 2005. Phenotypic and genotypic identification of lactic acid bacteria from a small-scale facility producing traditional dry sausages. Journal Food Microbiology. 22(5).373-382. 7. Akhmaloka, Suharto,A., Nurbaiti,S., Tika, I.N.,Warganegara, F.M. 2006. Ribotyping identification of Thermophilic Bacterium From Papandayan Creater, Proc ITB Eng Science, 38B (1),1-10. 8. Iqbalsyah, T.M., Yusniar, Sartika, F., Febriani, 2006. A local Isolate of PLS 80 Capable of Producing a β-Lactams Antibiotic, The 6th Annual International Conference (AIC) , Banda Aceh. 9. Nabila, J.P., Febriani, Iqbalsyah, T.M., 2014. Screening of α-Amylase Production Ability of Four Thermo-Halophilic Bacteria Isolated From An Underwater Hot Spring In Pria Laot Sabang, ICONES FMIPA Unsyiah . 10. Atikah,Oesman, F., Iqbalsyah, T.M Febriani, 2014. Screening of Four Thermo- Halophilic Bacteria Isolated From Underwater Hot Spring in Pria Laot Sabang In Producing Proteases, ICONES FMIPA Unsyiah. 11. Gregoire, P., Bohli, M., Cayol, L. J., Joseph, M and Guasco, S. 2011. Caldilinea tarbalica sp. Nov., a Filamentous, thermophilic, anaerobic bacterium isolated from a deep hot aquifer in the aquitaine basin. Internasional Journal of Systematic and Evolutionary Microbiology, 61,1436-1441. 12. Park, H. M., Traiwan, J., Jung, Y. M and Kim, W. 2012. Gulosibacter chungangensis sp. Nov., an Actinomycete isolated from a marine sediment and emended description of the genus gulosibacter. Internasional Journal of Systematic and Evolutionary Microbiology. 62, 1055-1060. 13. He, S., Wang, H., Yan, X., Zhu, P., Chen, J. and Yang, R., 2013, Preparatife isolation and purification of macrolactin antibiotics from marine bacterium Bacillus amyloliquefaciens using high-speed counter-current chromatography in stepwise elution mode, Journal of Chromatography A, China. 1272 – 15-19. 14. Oku, N., Kawabata, K., Adachi, K., Katsuta, A., Shizuri, Y. 2009. Unnarmicins A and C, new antibacterial depsipeptides produced by marine bacterium photobacterium sp. MBIC06485. The Journal Of Antibiotics. Japan Antibiotics Research Association. 61(1): 11–17. 15. Bauer AW, Kirby WM, Sherris JC and Turck M 1966 Antibiotic susceptibility testing by a standardized single disk method. Am. J. Clin. Pathol. 45 (4) 493–496. 16. Hancu G, Simon B, Kelemen H, Rusu A, Mircia E and Gyeresi A 2013. Thin layer chromatographic analysis of Beta-lactam antibiotics. Adv. Pharma. Bull. 3(2) 367-371. 17. Mohandass, C., Rajasabathy, R., Ravindran, C., Colaco, A., Santos, R. & Meena, R. M.. (2012). Bacterial Diversity and Their Adaptations in The Shallow Water Castro Seamount (DJCS), Azores, Portugal. Cah. Biol. Mar. 53 : 65-76. 18. Iqbalsyah TM, Saidi N, Maulyna N, Helwati H, Aura N, Febriani. 2016. Skrining antibiotik dari bakteri thermo-halofilik isolat Pria Laot Sabang (PLS A dan 76). Prosiding Seminar Nasional XX Perhimpunan Biokimia Dan Biologi Molekuler Indonesia (PBBMI) 47-55. 19. Febriani, Ramayanti, Iqbalsyah, T.M, Khairan, Oesman, F., 2014. Antibiotic production From Thermophilic Jaboi Sabang Local Isolate Using TSB Medium, Proceeding of Aceh International Pharmacy Conference. 43-47. 20. Kumar, A., Saini, P., Shrivastava, J.N., 2009. Production of Peptide antifungal antibiotic and Biocontrol Activity of Bacillus subtilis. Indian Journal of Experimental Biology, 47: 57-62. 21. Venugopalan, V.,Singh, B., Verma, N., Nahar,P.,Bora, T.C., Das, R.H., Gautam, H.K., 2008. Screening of Thermophilis From Municipal Solid Waste and Their Selective Antimicrobial Profile, Current Research in Bacteriology1 (1): 17-22. 22. El-Damerdash HA 2012. A Simple and inexpensive procedure for chromosomal DNA extraction from Streptococcus thermophilus Strains. Middle-East J. Sci. Res. 11 (1) : 13- 18. 23. Baker, G.C., Smith, J.J., Cowan, D.A. 2003. Review and Re-analysis of Domain- Spesific 16S Primers (Review Article). J. Microbiol. Meth. 55 (3) : 541-555. 24. Nei M and Kumar S 2000 Molecular evolution and phylogenetics. Oxford University Press, Inc. New York. 25. Drancourt M, Bollet C, Carlioz, Martelin R, Gayral JP, Raoult D 2000 16S ribosomal DNA sequence analysis of a large collection of environmental and clinical unidentifiable bacterial isolates, J. Clin. Microbiol. 38 3623-3630.