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369049-639 Synopsis User Guide
369049-639 Synopsis User Guide
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Table of Contents
Disclaimer...................................................................................................................................................... 2
Intent Statement .......................................................................................................................................... 2
Indications for Use ....................................................................................................................................... 3
Intended Use ................................................................................................................................................ 3
Warnings and Cautions ................................................................................................................................ 4
Synopsis Overview ....................................................................................................................................... 5
Synopsis General Set Up Instructions .......................................................................................................... 6
Required Computer Specifications .............................................................................................................. 6
Synopsis Settings .......................................................................................................................................... 7
Recording and Reviewing with Synopsis ..................................................................................................... 9
Peak Envelope ............................................................................................................................................ 13
Technical Information ............................................................................................................................ 13
Setting Up Peak Envelope Trend ........................................................................................................... 14
Envelope Asymmetry ................................................................................................................................. 15
Technical Information ............................................................................................................................ 15
Setting Up Envelope Asymmetry Trend ................................................................................................ 16
Spectrogram ............................................................................................................................................... 18
Technical Information ............................................................................................................................ 18
Setting Up Spectrogram Trend .............................................................................................................. 18
Band Power ................................................................................................................................................ 20
Technical Information ............................................................................................................................ 20
Setting Up Band Power Trend ................................................................................................................ 21
Power Ratio ................................................................................................................................................ 22
Technical Information ............................................................................................................................ 22
Setting Up Power Ratio Trend ............................................................................................................... 23
Spectral Entropy ......................................................................................................................................... 25
Technical Information ............................................................................................................................ 25
Setting Up Spectral Entropy Trend ........................................................................................................ 26
Synopsis Notification.................................................................................................................................. 28
Technical Information ............................................................................................................................ 28
Setting Up Synopsis Notification ........................................................................................................... 28
Customer Support and Contact Information .............................................................................................. 29
Disclaimer
© 2020 Cadwell Industries, Inc. All rights reserved.
No part of this publication may be reproduced, transmitted, transcribed, stored in a retrieval system,
translated into any language or computer language, in any form, by any means, electronic, mechanical,
optical, chemical, manual, or otherwise without prior written consent of Cadwell Industries, Inc.
Disclaimer
Conclusions and decisions based on the use of this product are the responsibility of the user. Cadwell
does not accept any liability or responsibility for damages arising out of the use of or inability to use this
product. This manual provides an operational summary for the Cadwell Synopsis software-only device. It
does not provide training. It is assumed that the user has adequate training.
This document may contain technical inaccuracies or typographical errors. Changes are periodically
made to the information herein; these changes will be incorporated into future revisions of this
document. Features and specifications are subject to change without notice.
Cadwell does not accept any liability for the use or misuse, direct or indirect, of this product. Users must
accept all responsibility for any results obtained by or concluded from data obtained by the products.
The user must accept all responsibility for results obtained by software from Cadwell Industries, Inc.
Trademark Notices
Cadwell is a registered trademark. Other brand and product names are trademarks or registered
trademarks of their respective holders.
Cadwell Industries, Inc. reserves the right to modify, delete, extend, or improve features described
herein without notice.
Intent Statement
This manual is a basic guide to installing and operating your Cadwell Synopsis Software. Please refer to
the following information sources for more detail on operating your product:
This device does not provide any diagnostic conclusion about the patient’s condition to the user as
part of its output. The software does not contain automated detection algorithms.
Intended Use
The Cadwell Synopsis Software is intended to be used for post-hoc analysis of electroencephalograph
(EEG) data using conventional methodology to output and display standard EEG parameters for
interpretation by a qualified user. The device uses software algorithms as a tool to analyze EEG
recordings to calculate conventional EEG parameters. (e.g. spectral edge frequency, percent alpha,
asymmetry).
This device does not provide any diagnostic conclusion about the patient’s condition to the user as part
of its output. The software does not contain automated detection algorithms.
Synopsis Overview
Cadwell Synopsis is a software-only device for use with EEG data. Cadwell Synopsis receives EEG data as
an input, and calculates and displays the following quantitative measures of electroencephalographic
data: peak envelope, envelope asymmetry, spectrogram, band power, power ratio, and spectral
entropy. The Cadwell Synopsis device performs analysis on a user defined set of EEG channels within the
EEG data and displays graphical results to be interpreted by qualified medical practitioners. Additional
user -selectable parameters are available depending on the quantitative measure selected for display.
Synopsis detection is an optional feature that can provide notifications based on user-defined
thresholds. For applicable Synopsis measures, Synopsis detection will mark instances of data that exceed
the user-defined threshold setting. Two levels of thresholds are set to determine when the user may be
notified. The first threshold is set based on an individual quantitative measure. When a value exceeds
this user-defined threshold, a green event is shown in the Synopsis window. The second threshold is set
based on the total number of individual events. This threshold determines the number of individual
Synopsis events that must occur simultaneously for Synopsis to consider the time point as an overall
Synopsis event. When this threshold is met, the events are marked in red. Additionally, Synopsis displays
all events manually marked by the reviewer as black events in the Synopsis window. It is optional to
have Synopsis events automatically recorded in the EEG data.
Synopsis settings, parameters, and user-defined thresholds can be adjusted at any time during use.
When Synopsis settings are changed, the results are recalculated and displayed to the user. Multiple
instances of the Cadwell Synopsis can be created to examine different montages and different
quantitative measures. Synopsis quantitative measures can be added and/or removed at any time
during use, and Synopsis results are recalculated. Synopsis results are stored with the EEG record and
are included in record management operations, such as deleting or archiving.
Synopsis Settings
Default settings for Synopsis are stored and configured in the Administration panel of the acquisition
software. To add trends and adjust settings, select Synopsis Settings from the Administration panel
menu.
1. Select this option to add a new Settings panel. These panels show up in a pulldown menu when
setting up study types. Name the panel and then add trends and adjust settings accordingly for
the new panel.
2. Select this option to create a copy of the selected Settings panel. The copied panel can be
renamed and edited as required.
3. Select this option to delete the selected Settings panel from the list.
4. Select this option to add a trend to the selected Settings panel. Once selected, a list of available
trends will appear. Select the desired trend from the list and select OK. After selecting the trend,
the analyzer settings window will open. At this point, the trend settings are defined. These
settings include but are not limited to inputs to be analyzed, filter values, and output display
color. Additional user-adjustable parameters may be available depending on the trend selected.
Once the settings are selected, select OK. The trend will now appear in the list for the selected
panel. NOTE: These settings can be changed at any time during analysis. The settings selected in
this setup step will be saved as Default values for future analysis.
5. Select this option to make a copy of an existing trend in a panel. This feature is useful to add
new trends that are similar in settings to existing trend. When selected, the copied trend is
immediately added to the list in the panel. Select the edit icon (labelled number 7) to adjust
settings for this trend.
6. Select this option to delete the selected trend from the current panel.
7. Select this option to edit the settings for the selected trend. The trend settings window will be
displayed. Make all desired changes and select OK when complete.
8. Select this settings icon to adjust the epoch length of data that is analyzed. Also, a checkbox is
available to enable or disable Synopsis from marking notifications in the EEG trace data.
9. Use this column to set the threshold value for each trend in the panel. These threshold values
are used for Synopsis detections and can be changed at any point during Synopsis analysis.
10. Set the overall threshold value for Synopsis detection. This threshold value determines the
number of trend events that must occur simultaneously before an overall Synopsis event is
triggered.
Once a new trend panel is created, it can be assigned as the default panel for a specific study type.
Select Study Type Settings from the Administration panel menu. Set the Synopsis Settings option to the
desired default Synopsis panel. When a new study of this type is started, the Synopsis settings will
default to this selected panel.
There are various controls and options available in the Synopsis window. The trends window contains a
subset of the options available in the detection window. Therefore, the list below summarizes the
controls and features of the detection window shown in Figure 2:
At the bottom of the Synopsis window, the horizontal axis can be adjusted using the Elapsed button and
the pulldown menu. The horizonal axis determines the time segment (in hours or minutes) of data that
is displayed in the Synopsis window. This value is shared between all trend windows. The following
options and controls are available:
1. Select this button to change units of the x-axis. If the button says Elapsed, you are viewing the
elapsed recording duration. If the button says Time, you are viewing the time and date at which
the recording was performed.
2. Use this drop-down menu to change the scale of the x-axis. This option will change how much
data is displayed in the Synopsis window. The available options are: 15min, 30min, 1hr, 2hrs,
4hrs, 8hrs, 16hrs, 24hrs, and All. The default view is All.
Along with the overall Synopsis window controls and options, individual analyzer options are available.
These options are explained for each trend in the sections to follow, but are summarized using Figure 4
below:
1. Select the setting gear within each individual trend to open the analyzer settings window.
Settings can be adjusted for any trend at any time. Synopsis automatically recalculates results
when necessary.
2. Select the Red X to delete the trend from the panel.
3. Hover over the information icon to display the specific settings of the trend (including inputs
being analyzed).
4. Move the slide bar to adjust the vertical axis scale.
5. This vertical bar links the location of the analyzer to the same location in the EEG trace data.
When this bar is moved, the EEG trace data will re-adjust position to match the new selected
location. Likewise, if the user selects a new location in the EEG trace data, the vertical bar will
re-locate in the Synopsis window to match the new selected location.
6. Drag the horizontal bar up and down to set the Synopsis detection threshold value. This
threshold bar can be re-adjusted at any point, and Synopsis will reanalyze for events based on
the new threshold value.
7. This circle icon will turn yellow when the output value is over the user-specified threshold.
The Cadwell Synopsis aEEG algorithm is implemented as follows, per the description of the CFM:
1. An asymmetrical band pass filter is applied to the EEG channel data. Figure 5 shows the Ideal
CFM filter as described by Prior and Maynard on the left and the response of the filter as
implemented in Cadwell Synopsis on the right.
Figure 5 The ideal CFM filter response curve per Prior and Maynard (left) and the Cadwell Synopsis filter
response curve (right)
2. Per Prior and Maynard, the resultant filtered EEG channel data is semilog compressed, rectified,
and a low-pass filter with a 0.5 second time-constant is applied which results in a smooth-line
approximation of peak amplitude with the DC component retained. The EEG channel data is
compressed using a linear scale for values from 0-10uV and a logarithmic scale for values from
10-100 uV, and filtered using a low-pass filter with a 0.5 S time-constant. The filter
implemented by Cadwell Synopsis aEEG analyzer is a second order Butterworth filter with a
0.3182 Hz cutoff frequency, which equates to a 0.5 S time constant.
4. The minimum and maximum peak-values for each epoch of aEEG data are returned as data
points. In order to provide a time compressed display, the results of multiple epochs are
combined and a vertical line is drawn between the lowest minimum value and the largest
maximum value of the results. The number of results per vertical line depends on the time scale
displayed and epoch length. An implementation of the aEEG trend is shown in Figure 7 below.
Select the color for the output trend. Enter a name for the output trend. The name will be displayed
above the output trend. Check/un-check the box to turn the notch filter on/off. Inputs can be selected
for analysis using two different selection modes: bipolar and referential. To select bipolar inputs, select
Bipolar as the Selection Mode. Click and drag between the two electrodes. An arrow between the two
electrodes signifies a bipolar input (as shown for the left side inputs in Figure 6). To select referential
inputs, select Referential as the Selection Mode. Click a single electrode for an input. A black circle
appears around the input to signify a referential input. After the inputs are selected, press Ok. Synopsis
will automatically begin calculating and displaying the aEEG trend. The resulting trend will appear similar
to the following:
Selecting the gear icon in the right corner will open the Analyzer Setup window discussed above.
Settings can be adjusted/updated at any time and Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. Selecting the blue information icon
in the left corner will display information about the displayed trend. Figure 8 shows an example of the
information icon for the aEEG trend.
The selected Synopsis analyzer, Notch filter setting, and selected inputs are shown in this window and
can be viewed at any time.
Peak Envelope
Technical Information
The peak envelope trend analyzer provides insight to EEG signal amplitudes. Peak envelope detects the
maximum EEG amplitude contained within an epoch of specified duration, and displays a plot of those
maximum values over time. Peak envelope is implemented as follows:
1. A band-pass filter is applied to the EEG channel data according to high-cut and low-cut
frequencies defined by the user. See the “Setting Up Peak Envelope Trend” for a detailed
description of user adjustable settings.
2. Absolute values are taken for all measurements within the user specified epoch. The epoch
length is a parameter shared between all analyzers run during the instance of Cadwell Synopsis.
3. The maximum value for each epoch of EEG data is returned as a data point.
4. Cadwell Synopsis optionally implements a sliding median average. A window size is specified by
the user. The median peak envelope value is calculated within the specified window size. The
resulting median value is used to represent the peak envelope value for the epoch. For example,
a window size of ‘5’ indicates that the sliding median is calculated from data over the last 5
epochs, whereas a window size of ‘1’ indicates that no sliding median is calculated.
5. The data points for each epoch are displayed as a bar graph. The vertical axis is a microvolt,
linear scale. The horizontal axis is a time, linear scale. Both axes are user-adjustable. An
implementation of the peak envelope trend is shown in Figure 10.
Enter the low frequency and high frequency values for the band pass filter. The Epoch count to average
field specifies the window size for the sliding median calculation. If no sliding median is desired, enter a
value of “1”. Enter a name for the output trend. The name will be displayed above the output trend.
Check/un-check the box to turn the notch filter on/off. Select the color for the output trend. Finally,
select the inputs to be analyzed. Inputs can be selected using two different selection modes: bipolar and
referential. To select bipolar inputs, select Bipolar as the Selection Mode. Click and drag between the
two electrodes. An arrow between the two electrodes signifies a bipolar input (as shown for the left side
inputs in Figure 9). To select referential inputs, select Referential as the Selection Mode. Click a single
electrode for an input. A black circle appears around the input to signify a referential input (as shown for
input “O1” in Figure 9). After the inputs are selected, press Ok. Synopsis will automatically begin
calculating and displaying the peak envelope trend. The resulting trend will appear similar to the
following:
Selecting the gear icon in the right corner will open the Analyzer Setup window discussed above.
Settings can be adjusted/updated at any time. Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. The sliding bar to the left of the
trend output adjusts the y-axis. Selecting the blue information icon in the left corner will display
information about the displayed trend. Figure 11 shows an example of the information icon for the peak
envelope trend.
The selected Synopsis analyzer, frequency band, window size, notch filter, and selected inputs are
shown in this window and can be viewed at any time.
Envelope Asymmetry
Technical Information
Envelope asymmetry compares the EEG signal amplitudes between left and right hemispheres using
data obtained from the peak envelope quantitative measure. Envelope asymmetry utilizes the
processing steps from the peak envelope quantitative measure and additionally performs inter-
hemisphere amplitude comparisons. Envelope asymmetry is implemented as follows:
1. Peak envelope is performed on the selected inputs. If an input is selected on one hemisphere,
the homologous input is automatically selected on the opposite hemisphere. For example, if C3-
F3 pair is selected on the left hemisphere, C4-F4 is automatically selected on the right
hemisphere. The user-selectable options available with peak envelope are also available for
envelope asymmetry and are explained in detail in the following section.
2. Peak envelope values for left-hemisphere (LH) inputs, at each given epoch time point, are
averaged. A single value is returned. The same process is repeated for right-hemisphere (RH)
inputs.
3. The envelope asymmetry value (EA) for a given epoch is calculated using the following
mathematical operation:
(𝑅𝐻 − 𝐿𝐻)
𝐸𝐴 = × 100%
max(𝑅𝐻, 𝐿𝐻)
4. The data points for each epoch are displayed as a bar graph. The vertical axis is a unit of percent,
linear scale. The horizontal axis is a time, linear scale. Both axes are user-adjustable. An example
of the envelope asymmetry implementation is shown in Figure 13 below.
Enter the low frequency and high frequency values for the band pass filter. The Epoch count to average
field specifies the window size for the sliding median calculation. If no sliding median is desired, enter a
value of “1”. Enter a name for the output trend. The name will be displayed above the output trend.
Check/un-check the box to turn the notch filter on/off. Select the color for the output trend. Finally,
select the inputs to be analyzed. For this trend, homologous inputs are automatically selected together.
Therefore, when an input is selected on one hemisphere, the homologous input is automatically
selected on the opposite hemisphere. Inputs can be selected using two different selection modes:
bipolar and referential. To select bipolar inputs, select Bipolar as the Selection Mode. Click and drag
between the two electrodes. An arrow between the two electrodes signifies a bipolar input (as shown
for F3-C3 and F4-C4 inputs in Figure 12). To select referential inputs, select Referential as the Selection
Mode. Click a single electrode for an input. A black circle appears around the input to signify a
referential input (as shown for input “P3, P4, O1, O2” in Figure 12). Midline inputs cannot be used with
this analyzer; therefore, these inputs are grayed out and cannot be selected. After the inputs are
selected, press Ok. Synopsis will automatically begin calculating and displaying the envelope asymmetry
trend. The resulting trend will appear similar to the following:
Selecting the gear icon in the right corner will open the Analyzer Setup window discussed above.
Settings can be adjusted/updated at any time and Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. The sliding bar to the left of the
trend output adjusts the y-axis. Selecting the blue information icon in the left corner will display
information about the displayed trend. Figure 14 shows an example of the information icon for the
envelope asymmetry trend.
The selected Synopsis analyzer, frequency band, window size, notch filter, and selected inputs are
shown in this window and can be viewed at any time.
Spectrogram
Technical Information
The Spectrogram trend extracts and displays the power spectrum from EEG data. This trend is
implemented as follows:
1. A fast Fourier transform (FFT) algorithm is applied to a user-selected epoch length of EEG data.
The Cadwell Synopsis implements standard methods to calculate the power spectrum (P) from
FFT data using the following expression:
1
𝑃(𝜔) = |𝑋(𝜔)|2
𝑁
where P(ω) is the power spectrum; X(ω) is the FFT of an epoch of data; N is the number of
points.
2. The power spectrum is displayed as a surface plot expressing the Power (z-axis) of each
frequency (y-axis) over the time series (x-axis) of the EEG data. Power is expressed in µV2 and
displayed by the color palette selected in the analyzer settings window (shown in Figure 15). An
implementation of the spectrogram quantitative measure can be seen in Figure 16.
Enter the frequency band to be used in calculating an additional band power output. The band power
output is displayed as a solid white line transposed on top of the Spectrogram trend. Enter top
frequency range for the Spectrogram trend output. Enter a name for the output trend. The name will be
displayed above the output trend. Check/un-check the box to turn the notch filter on/off. Select the
color for the output trend. Inputs can be selected for analysis using two different selection modes:
bipolar and referential. To select bipolar inputs, select Bipolar as the Selection Mode. Click and drag
between the two electrodes. An arrow between the two electrodes signifies a bipolar input (as shown
for the left side inputs in Figure 15). To select referential inputs, select Referential as the Selection
Mode. Click a single electrode for an input. A black circle appears around the input to signify a
referential input (as shown for O1 input in Figure 15). After the inputs are selected, press Ok. Synopsis
will automatically begin calculating and displaying the Spectrogram trend. The resulting trend will
appear similar to the following:
Selecting the gear icon in the right corner will open the Analyzer Settings window discussed above.
Settings can be adjusted/updated at any time; Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. The sliding bar to the left of the
trend output adjusts the y-axis. Selecting the blue information icon in the left corner will display
information about the displayed trend. Figure 17 shows an example of the information icon for the
Spectrogram trend.
The selected Synopsis analyzer, the frequency band, Notch filter setting, and selected inputs are shown
in this window and can be viewed at any time.
Band Power
Technical Information
Band power displays the percentage of power over a user-specified frequency band. Band power utilizes
the processing steps from the spectrogram trend and then calculates the relative power of the user-
specified frequency band against the broadband spectrogram power. Band power is implemented as
follows:
∑𝜔2
𝑖=𝜔1 𝑃(𝜔)𝑖
𝐵𝑃 = × 100%
∑ 𝑃(𝜔)
where ω1 and ω2 are the frequency range limits specified by the user.
3. The vertical axis is a unit of percent, linear scale. The horizontal axis is a unit of time, linear scale.
Both of the axes are user adjustable. An implementation of band power is shown in Figure 19
below.
Enter the start and stop frequency for the desired power band. For example, to see alpha power enter 8
as the start frequency and 13 as the stop frequency. Enter a name for the output trend. The name will
be displayed above the output trend. Check/un-check the box to turn the notch filter on/off. Select the
color for the output trend. Inputs can be selected for analysis using two different selection modes:
bipolar and referential. To select bipolar inputs, select Bipolar as the Selection Mode. Click and drag
between the two electrodes. An arrow between the two electrodes signifies a bipolar input (as shown
for the left and right inputs in Figure 18). To select referential inputs, select Referential as the Selection
Mode. Click a single electrode for an input. A black circle appears around the input to signify a
referential input (as shown for the midline inputs in Figure 18). After the inputs are selected, press Ok.
Synopsis will automatically begin calculating and displaying the Band Power trend. The resulting trend
will appear similar to the following:
Selecting the gear icon in the right corner will open the Analyzer Settings window discussed above.
Settings can be adjusted/updated at any time and Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. The sliding bar to the left of the
trend output adjusts the y-axis. Selecting the blue information icon in the left corner will display
information about the displayed trend. Figure 20 shows an example of the information icon for the Band
Power trend.
The selected Synopsis analyzer, frequency band, notch filter setting, and selected inputs are shown in
this window and can be viewed at any time.
Power Ratio
Technical Information
Power ratio displays the ratio of the power data for two discrete bands of frequencies. Power ratio
utilizes the processing steps from the spectrogram measure and adds steps to compare the power of
two user-specified frequency bands. Power ratio is implemented as follows:
1. FFT is performed on all selected EEG inputs and power spectrum is calculated based on the
implementation described in the Spectrogram section above.
2. The following mathematical operation is performed to calculate the specified power ratio:
∑𝜔 2
𝑖=𝜔1 𝑃 (𝜔)𝑖
𝑃𝑅 =
∑𝜔 4
𝑖=𝜔 𝑃 (𝜔)𝑖
3
where PR is the power ratio and the numerator and denominator are the sum of the respective user-
specified frequency bands. The frequency bands used to calculate the numerator and denominator
cannot overlap. The resulting power ratio value is plotted on the vertical axis as a function of time on
the horizontal axis. An implementation of power ratio is shown in Figure 22 below.
Enter the frequency band to be used in the numerator and denominator of the calculation. For example,
to view alpha/delta ratio, the numerator band will be 8-13, and the denominator band will be 1-4. Enter
a name for the output trend. The name will be displayed above the output trend. Check/un-check the
box to turn the notch filter on/off. Select the color for the output trend. Finally, select inputs to be
analyzed. Inputs can be selected for analysis using two different selection modes: bipolar and
referential. To select bipolar inputs, select Bipolar as the Selection Mode. Click and drag between the
two electrodes. An arrow between the two electrodes signifies a bipolar input (as shown for the right
hemisphere inputs in Figure 21). To select referential inputs, select Referential as the Selection Mode.
Click a single electrode for an input. A black circle appears around the input to signify a referential input
(as shown for the O2 input in Figure 21). After the inputs are selected, press Ok. Synopsis will
automatically begin calculating and displaying the Power Ratio trend. The resulting trend will appear
similar to the following:
Selecting the gear icon in the right corner will open the Analyzer Settings window discussed above.
Settings can be adjusted/updated at any time and Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. The sliding bar to the left of the
trend output adjusts the y-axis. Selecting the blue information icon in the left corner will display
information about the displayed trend. Figure 23 shows an example of the information icon for the
Power Ratio trend.
The selected Synopsis analyzer, numerator frequency band, denominator frequency band, Notch filter
setting, and selected inputs are shown in this window and can be viewed at any time.
Spectral Entropy
Technical Information
Spectral Entropy displays the entropy, or randomness, of EEG data. Spectral entropy adds additional
steps to the processing done for the spectrogram trend. Spectral entropy is implemented as follows:
1. FFT and power spectrum are calculated on all selected EEG inputs. This implementation is
described further in the Spectrogram section above.
2. The power spectrum for a user-specified frequency band is normalized by performing the
following mathematical operation:
𝑃(𝜔)
𝑃𝑛𝑜𝑟𝑚 (𝜔) = =1
∑ 𝑃(𝜔)
3. Finally, spectral entropy values are calculated per the equation below. Spectral entropy is
summed for the frequency range and the entropy value is normalized to range between 100
(maximum irregularity) and 0 (complete regularity).
Enter the start and stop frequency values to be included in the calculation. Enter the “Notify If…” values.
This number determines the entropy value that the recording must be below or above for the text color
to change. Select the color for the output trend and the color for the “Notify If…” value. Enter a name
for the output trend. The name will be displayed above the output trend. Check/un-check the box to
turn the notch filter on/off. Finally, select inputs for analysis. Inputs can be selected for analysis using
two different selection modes: bipolar and referential. To select bipolar inputs, select Bipolar as the
Selection Mode. Click and drag between the two electrodes. An arrow between the two electrodes
signifies a bipolar input. To select referential inputs, select Referential as the Selection Mode. Click a
single electrode for an input. A black circle appears around the input to signify a referential input. After
the inputs are selected, press Ok. Synopsis will automatically begin calculating and displaying the
Spectral Entropy trend. The resulting trend will appear similar to the following:
In the above example, the “Notify If” threshold was set at 60. At the selected time point, the entropy
value was 65; therefore, the reported entropy value is show in yellow (the “Notify If” color).
Selecting the gear icon in the right corner will open the Analyzer Setup window discussed above.
Settings can be adjusted/updated at any time and Synopsis will automatically update the trend output.
Selecting the red X will remove the trend from the Synopsis window. Selecting the blue information icon
in the left corner will display information about the displayed trend. Figure 26 shows an example of the
information bubble for the Spectral Entropy trend.
The selected Synopsis analyzer, frequency band, notch filter setting, and selected inputs are shown in
this window and can be viewed at any time.
Synopsis Detection
Technical Information
Synopsis detection is an optional feature that can provide over-threshold notifications based on user-
defined thresholds. The detection feature can be added in addition to the analyzer trend window. Both
of the functions and associated settings are described below. For applicable analyzers, Synopsis
detection will mark instances of data that exceed a user-defined threshold setting. Two levels of
thresholds are set to determine when the user may be notified. The first threshold is set at an individual
analyzer level. When a single analyzer value exceeds this user-defined threshold, a green event is shown
in the Synopsis window. Additionally, a circle indicator is adjacent to each applicable trend output (seen
in Figure 27 below) and this indicator will turn yellow when the trend value is over-threshold. The
second threshold is set for the overall Synopsis event window. This threshold allows the user to set the
number of individual analyzer events that must occur simultaneously for Synopsis to consider the time
point as an overall Synopsis event. When this threshold is met, the events are shown in red and the
indicator next to the overall Synopsis Events trend turns yellow. Additionally, Synopsis displays all events
manually marked by the reviewer as black events in the Synopsis window. The user can select whether
to have the red and green Synopsis events documented in the EEG data.
US Customers:
International Customers:
Support Hours:
Service department support: Monday through Friday from 6:30 am to 5:00 pm PST
service@cadwell.com
• You continue to experience difficulty after troubleshooting a problem. Cadwell Industries, Inc. has
a rapid, cost-effective method for troubleshooting and servicing equipment. Most problems can
be diagnosed over the telephone, and repairs can be performed by sending in the defective part.
• You wish to order optional equipment.
1. Have your customer identification number and serial number readily available. Have a person
who is familiar with the equipment speak to service or application support. This person should
be able to provide an accurate description of the problem. Preferably, the person calling will be
in front of the equipment when making the call.
2. Call the customer support number, and ask for the service department or application support,
as applicable to your problem. In either case, the Cadwell support staff will work with you to
solve the problem, will determine if an exchange or repair of parts is necessary, and will instruct
you on appropriate shipping arrangements as applicable. Please decontaminate equipment as
applicable before returning it to Cadwell.