Page: 1

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

1. PRODUCT AND COMPANY IDENTIFICATION

Product identifier
Trade name : Inhibex™ 501
gas hydrate inhibitors
™ Trademark, Ashland or its subsidiaries, registered in
various countries

Relevant identified uses of the substance or mixture and uses advised against

Details of the supplier of the safety data Emergency telephone number

sheet 1-800-ASHLAND (1-800-274-5263), or contact
Ashland your local emergency telephone number at 995
200 Pandan Loop, #07-01 Pantech 21
Singapore 128388
Singapore Product Information
Tel: 6775-5366 Tel: 6775-5366

EHSProductSafety@ashland.com

2. HAZARDS IDENTIFICATION
GHS Classification
Acute toxicity (Inhalation) : Category 4

Serious eye damage/eye : Category 2

irritation

GHS label elements

Hazard pictograms :

Signal word : Warning

Hazard statements : H319 Causes serious eye irritation.

H332 Harmful if inhaled.

Precautionary statements : Prevention:

P261 Avoid breathing dust/ fume/ gas/ mist/ vapours/ spray.
P264 Wash skin thoroughly after handling.
P271 Use only outdoors or in a well-ventilated area.

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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

P280 Wear eye protection/ face protection.

Response:
P304 + P340 + P312 IF INHALED: Remove person to fresh air
and keep comfortable for breathing. Call a POISON
CENTER/doctor if you feel unwell.
P305 + P351 + P338 IF IN EYES: Rinse cautiously with water
for several minutes. Remove contact lenses, if present and
easy to do. Continue rinsing.
P337 + P313 If eye irritation persists: Get medical advice/
attention.

Other hazards which do not result in classification

No information available.
3. COMPOSITION/INFORMATION ON INGREDIENTS
Substance / Mixture : Mixture

Hazardous components
Chemical name CAS-No. Classification Concentration (%)
ETHYLENE GLYCOL 111-76-2 Acute Tox. 4; H302 >= 50,00 - < 70,00
MONOBUTYL ETHER Acute Tox. 4; H332
Acute Tox. 4; H312
2; H315
2; H319

4. FIRST AID MEASURES

General advice : Move out of dangerous area.

Show this safety data sheet to the doctor in attendance.
Do not leave the victim unattended.

If inhaled : Move to fresh air.

IF INHALED: Call a POISON CENTER/ doctor if you feel
unwell.
Keep patient warm and at rest.
If unconscious, place in recovery position and seek medical
advice.

In case of skin contact : If on skin, rinse well with water.

First aid is not normally required. However, it is
recommended that exposed areas be cleaned by washing
with soap and water.
If on clothes, remove clothes.

In case of eye contact : Immediately flush eye(s) with plenty of water.

2 / 14

SAFETY DATA SHEET
Inhibex™ 501 gas hydrate inhibitors
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682
If swallowed
Most important symptoms
and effects, both acute and
delayed
Notes to physician
5. FIREFIGHTING MEASURES
Suitable extinguishing media
Unsuitable extinguishing
media
Specific hazards during
firefighting
Hazardous combustion
products
Specific extinguishing
Page: 3
Revision Date: 10/05/2017
Print Date: 11.04.2021
SDS Number: R0718547
Version: 2.0
Remove contact lenses.
Protect unharmed eye.
: IF SWALLOWED: Call a POISON CENTER/doctor if you feel
unwell.
Do not give milk or alcoholic beverages.
Never give anything by mouth to an unconscious person.
If symptoms persist, call a physician.
: Signs and symptoms of exposure to this material through
breathing, swallowing, and/or passage of the material through
the skin may include:
irritation (nose, throat, airways)
Bloody urine
Difficulty in breathing
Causes serious eye irritation.
Harmful if inhaled.
: No hazards which require special first aid measures.
: Use extinguishing measures that are appropriate to local
circumstances and the surrounding environment.
Water spray
Foam
Carbon dioxide (CO2)
Dry chemical
: High volume water jet
: If product is heated above its flash point it will produce vapors
sufficient to support combustion. Vapors are heavier than air
and may travel along the ground and be ignited by heat, pilot
lights, other flames and ignition sources at locations near the
point of release.
Do not allow run-off from fire fighting to enter drains or water
courses.
: carbon dioxide and carbon monoxide
Aldehydes
Ketones
Organic acids
: Use a water spray to cool fully closed containers.
3 / 14

SAFETY DATA SHEET
Inhibex™ 501 gas hydrate inhibitors
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682
methods
Special protective equipment
for firefighters
6. ACCIDENTAL RELEASE MEASURES
Personal precautions,
protective equipment and
emergency procedures
Environmental precautions
Methods and materials for
containment and cleaning up
7. HANDLING AND STORAGE
Advice on protection against
fire and explosion
Advice on safe handling
Page: 4
Revision Date: 10/05/2017
Print Date: 11.04.2021
SDS Number: R0718547
Version: 2.0
Product is compatible with standard fire-fighting agents.
: In the event of fire, wear self-contained breathing apparatus.
: Remove all sources of ignition.
Use personal protective equipment.
Ensure adequate ventilation.
Persons not wearing protective equipment should be excluded
from area of spill until clean-up has been completed.
Comply with all applicable federal, state, and local regulations.
Suppress (knock down) gases/vapours/mists with a water
spray jet.
: Prevent product from entering drains.
Prevent further leakage or spillage if safe to do so.
If the product contaminates rivers and lakes or drains inform
respective authorities.
: Contain spillage, and then collect with non-combustible
absorbent material, (e.g. sand, earth, diatomaceous earth,
vermiculite) and place in container for disposal according to
local / national regulations (see section 13).
Keep in suitable, closed containers for disposal.
: No sparking tools should be used. Keep away from open
flames, hot surfaces and sources of ignition.
: Avoid formation of aerosol.
Provide sufficient air exchange and/or exhaust in work rooms.
Do not breathe vapours/dust.
Do not smoke.
Container hazardous when empty.
Avoid contact with skin and eyes.
Smoking, eating and drinking should be prohibited in the
application area.
For personal protection see section 8.
Dispose of rinse water in accordance with local and national
regulations.
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 Page: 5

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Conditions for safe storage : Keep container tightly closed in a dry and well-ventilated
place.
Observe label precautions.
No smoking.

8. EXPOSURE CONTROLS/PERSONAL PROTECTION

Components with workplace control parameters

Components CAS-No. Value type Control Basis
(Form of parameters /
exposure) Permissible
concentration
ETHYLENE GLYCOL 111-76-2 PEL (long 25 ppm SG OEL
MONOBUTYL ETHER term) 121 mg/m3
Engineering measures : Provide sufficient mechanical (general and/or local exhaust)
ventilation to maintain exposure below exposure guidelines (if
applicable) or below levels that cause known, suspected or
apparent adverse effects.

Personal protective equipment

Respiratory protection : In the case of vapour formation use a respirator with an
approved filter.

Hand protection
Remarks : The suitability for a specific workplace should be discussed
with the producers of the protective gloves.

Eye protection : Wear chemical splash goggles when there is the potential for
exposure of the eyes to liquid, vapor or mist.

Skin and body protection : Wear as appropriate:

Impervious clothing
Safety shoes
Choose body protection according to the amount and
concentration of the dangerous substance at the work place.
Discard gloves that show tears, pinholes, or signs of wear.

Hygiene measures : Wash hands before breaks and at the end of workday.
When using do not eat or drink.
When using do not smoke.

9. PHYSICAL AND CHEMICAL PROPERTIES

Physical state : liquid

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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Colour : clear, yellow

Odour : ether-like

Odour Threshold : No data available

pH : No data available

Melting point/freezing point : < -40 °C

Boiling point/boiling range : 204,3 °C

Flash point : 64 °C

Evaporation rate : No data available

Flammability (solid, gas) : No data available

Upper explosion limit : No data available

Lower explosion limit : No data available

Vapour pressure : 1,173 hPa (25 °C)

Relative vapour density : No data available

Relative density : No data available

Density : 1,027 g/cm3

Solubility(ies)
Water solubility : soluble

Solubility in other solvents : No data available

Partition coefficient: n- : No data available

octanol/water

Thermal decomposition : No data available

Viscosity
Viscosity, dynamic : No data available

Viscosity, kinematic : No data available

Oxidizing properties : No data available

6 / 14
 Page: 7

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

10. STABILITY AND REACTIVITY

Reactivity : No decomposition if stored and applied as directed.

Chemical stability : Stable under recommended storage conditions.

Possibility of hazardous : Vapours may form explosive mixture with air.

reactions

Conditions to avoid : Heat, flames and sparks.

Do not allow evaporation to dryness.

Incompatible materials : Acids

aluminum
Amines
Ammonia
Bases
chlorates
Chlorine
salts of strong bases
Strong oxidizing agents

Hazardous decomposition : Aldehydes

products carbon dioxide and carbon monoxide
Organic acids
ketones

11. TOXICOLOGICAL INFORMATION

Information on likely : Inhalation

routes of exposure Skin contact
Eye Contact
Ingestion

Acute toxicity
Harmful if inhaled.
Product:
Acute oral toxicity : LD50 (Rat): > 2.000 mg/kg

Acute dermal toxicity : LD50 (Rabbit): > 2.000 mg/kg

Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:

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 Page: 8

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Acute oral toxicity : LD50 (Guinea pig): 1.200 mg/kg

Acute inhalation toxicity : LC50 (Rat): 2,17 mg/l

Exposure time: 4 h
Test atmosphere: dust/mist
Assessment: The component/mixture is classified as acute
inhalation toxicity, category 4.

Acute dermal toxicity : Assessment: The component/mixture is classified as acute

dermal toxicity, category 4.

LD50 (Rabbit): 400 - 500 mg/kg

Skin corrosion/irritation
Not classified based on available information.
Product:
Species: Rabbit
Result: No skin irritation

Result: Repeated exposure may cause skin dryness or cracking.

Remarks: May cause skin irritation in susceptible persons.

Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Species: Rabbit
Result: Irritating to skin.

Serious eye damage/eye irritation

Causes serious eye irritation.
Product:
Species: Rabbit
Result: Irritating to eyes.

Remarks: Vapours may cause irritation to the eyes, respiratory system and the skin., Causes
serious eye irritation.

Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Species: Rabbit
Result: Irritating to eyes.

Respiratory or skin sensitisation

Skin sensitisation: Not classified based on available information.
Respiratory sensitisation: Not classified based on available information.

8 / 14
 Page: 9

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Product:
Assessment: Did not cause sensitisation on laboratory animals.
Result: Did not cause sensitisation on laboratory animals.

Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Test Type: Maximisation Test
Species: Guinea pig
Assessment: Does not cause skin sensitisation.
Method: OECD Test Guideline 406

Germ cell mutagenicity

Not classified based on available information.
Product:
Genotoxicity in vitro : Test Type: Ames test
Result: negative

Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Genotoxicity in vitro : Test Type: Ames test
Test species: Salmonella typhimurium
Metabolic activation: with and without metabolic activation
Result: negative

Carcinogenicity
Not classified based on available information.
Reproductive toxicity
Not classified based on available information.
STOT - single exposure
Not classified based on available information.
STOT - repeated exposure
Not classified based on available information.
Aspiration toxicity
Not classified based on available information.
Further information
Product:
Remarks: No data available

12. ECOLOGICAL INFORMATION

Ecotoxicity
Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Toxicity to fish : LC50 (Oncorhynchus mykiss (rainbow trout)): 1.474 mg/l
Exposure time: 96 h
Test Type: static test
Method: OECD Test Guideline 203

9 / 14
 Page: 10

SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Toxicity to daphnia and other : EC50 (Daphnia magna (Water flea)): 1.550 mg/l
aquatic invertebrates Exposure time: 48 h
Test Type: static test
Method: OECD Test Guideline 202

Toxicity to algae : EC50 (Pseudokirchneriella subcapitata (green algae)): 911

mg/l
End point: Growth inhibition
Exposure time: 72 h
Test Type: static test
Method: OECD Test Guideline 201

Toxicity to fish (Chronic : NOEC (Danio rerio (zebra fish)): > 100 mg/l
toxicity) Exposure time: 21 d
Test Type: semi-static test
Method: OECD Test Guideline 204

No data available
Persistence and degradability
Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Biodegradability : Result: Readily biodegradable.
Biodegradation: 90,4 %
Exposure time: 28 d
Method: OECD Test Guideline 301B

No data available
Bioaccumulative potential
Components:
ETHYLENE GLYCOL MONOBUTYL ETHER:
Partition coefficient: n- : log Pow: 0,83
octanol/water

No data available
Mobility in soil
Components:
No data available
Other adverse effects
No data available
Product:
Additional ecological : No data available
information

Components:

10 / 14
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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

13. DISPOSAL CONSIDERATIONS

Disposal methods
General advice : Do not dispose of waste into sewer.
Do not contaminate ponds, waterways or ditches with
chemical or used container.
Send to a licensed waste management company.

Contaminated packaging : Empty remaining contents.

Dispose of as unused product.
Empty containers should be taken to an approved waste
handling site for recycling or disposal.
Do not re-use empty containers.
Do not burn, or use a cutting torch on, the empty drum.

14. TRANSPORT INFORMATION

International transport regulations

REGULATION
ID NUMBER PROPER SHIPPING NAME *HAZARD SUBSIDIARY PACKING MARINE
CLASS HAZARDS GROUP POLLUTANT /
LTD. QTY.

INTERNATIONAL AIR TRANSPORT ASSOCIATION - CARGO

Not dangerous goods

INTERNATIONAL AIR TRANSPORT ASSOCIATION - PASSENGER

Not dangerous goods

INTERNATIONAL MARITIME DANGEROUS GOODS

Not dangerous goods

ADR
Not dangerous goods

RID
Not dangerous goods

*ORM = ORM-D, CBL = COMBUSTIBLE LIQUID

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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Marine pollutant no

Dangerous goods descriptions (if indicated above) may not reflect quantity, end-use or region-specific
exceptions that can be applied. Consult shipping documents for descriptions that are specific to the
shipment.

15. REGULATORY INFORMATION

Safety, health and environmental regulations/legislation specific for the substance or

mixture

Workplace Safety and Health Act and Workplace Safety and Health (General Provisions)
Regulations: This product is subjected to the SDS, labelling, PEL and other requirements
in the Act/Regulations.
Environmental Protection and Management Act and : Not applicable
Environmental Protection and Management
(Hazardous Substances) Regulations

Fire Safety (Petroleum and Flammable Materials) : Not applicable

Regulations

The components of this product are reported in the following inventories:

DSL : All components of this product are on the Canadian DSL

AICS : Not in compliance with the inventory

ENCS : Not in compliance with the inventory

KECI : Not in compliance with the inventory

IECSC : q (quantity restricted)

PICCS : Not in compliance with the inventory

TSCA : On TSCA Inventory

Inventories
AICS (Australia), DSL (Canada), IECSC (China), REACH (European Union), ENCS (Japan), ISHL
(Japan), KECI (Korea), NZIoC (New Zealand), PICCS (Philippines), TCSI (Taiwan), TSCA (USA)

12 / 14
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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

16. OTHER INFORMATION

Further information
Revision Date: 10/05/2017

Full text of H-Statements

H302 Harmful if swallowed.
H312 Harmful in contact with skin.
H315 Causes skin irritation.
H319 Causes serious eye irritation.
H332 Harmful if inhaled.

Other information : The information accumulated herein is believed to be accurate

but is not warranted to be whether originating with the
company or not. Recipients are advised to confirm in advance
of need that the information is current, applicable, and suitable
to their circumstances. This SDS has been prepared by
Ashland's Environmental Health and Safety Department.

Sources of key data used to compile the Safety Data Sheet

Ashland internal data including own and sponsored test reports
The UNECE administers regional agreements implementing harmonised classification for
labelling (GHS) and transport.

Full text of other abbreviations

AICS - Australian Inventory of Chemical Substances; ANTT - National Agency for Transport by
Land of Brazil; ASTM - American Society for the Testing of Materials; bw - Body weight; CMR -
Carcinogen, Mutagen or Reproductive Toxicant; CPR - Controlled Products Regulations; DIN -
Standard of the German Institute for Standardisation; DSL - Domestic Substances List (Canada);
ECx - Concentration associated with x% response; ELx - Loading rate associated with x%
response; EmS - Emergency Schedule; ENCS - Existing and New Chemical Substances (Japan);
ErCx - Concentration associated with x% growth rate response; ERG - Emergency Response
Guide; GHS - Globally Harmonized System; GLP - Good Laboratory Practice; IARC -
International Agency for Research on Cancer; IATA - International Air Transport Association; IBC
- International Code for the Construction and Equipment of Ships carrying Dangerous Chemicals
in Bulk; IC50 - Half maximal inhibitory concentration; ICAO - International Civil Aviation

13 / 14
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SAFETY DATA SHEET Revision Date: 10/05/2017

Print Date: 11.04.2021
SDS Number: R0718547
Inhibex™ 501 gas hydrate inhibitors Version: 2.0
™ Trademark, Ashland or its subsidiaries, registered
in various countries
828682

Organization; IECSC - Inventory of Existing Chemical Substances in China; IMDG - International

Maritime Dangerous Goods; IMO - International Maritime Organization; ISHL - Industrial Safety
and Health Law (Japan); ISO - International Organisation for Standardization; KECI - Korea
Existing Chemicals Inventory; LC50 - Lethal Concentration to 50 % of a test population; LD50 -
Lethal Dose to 50% of a test population (Median Lethal Dose); MARPOL - International
Convention for the Prevention of Pollution from Ships; n.o.s. - Not Otherwise Specified; Nch -
Chilean Norm; NO(A)EC - No Observed (Adverse) Effect Concentration; NO(A)EL - No Observed
(Adverse) Effect Level; NOELR - No Observable Effect Loading Rate; NOM - Official Mexican
Norm; NTP - National Toxicology Program; NZIoC - New Zealand Inventory of Chemicals; OECD
- Organization for Economic Co-operation and Development; OPPTS - Office of Chemical Safety
and Pollution Prevention; PBT - Persistent, Bioaccumulative and Toxic substance; PICCS -
Philippines Inventory of Chemicals and Chemical Substances; (Q)SAR - (Quantitative) Structure
Activity Relationship; REACH - Regulation (EC) No 1907/2006 of the European Parliament and of
the Council concerning the Registration, Evaluation, Authorisation and Restriction of Chemicals;
SADT - Self-Accelerating Decomposition Temperature; SDS - Safety Data Sheet; TCSI - Taiwan
Chemical Substance Inventory; TDG - Transportation of Dangerous Goods; TSCA - Toxic
Substances Control Act (United States); UN - United Nations; UNRTDG - United Nations
Recommendations on the Transport of Dangerous Goods; vPvB - Very Persistent and Very
Bioaccumulative; WHMIS - Workplace Hazardous Materials Information System

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