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APV Homogenizers Lab Series 3003 03-08-2008 US
APV Homogenizers Lab Series 3003 03-08-2008 US
HOMOG E N I Z E R S
Now you can achieve fully reproducible results for
emulsions, dispersions, or cell disruption that can
Compact, versatile design specifically
be applied to full-scale production with complete
confidence.
developed for R&D laboratories within
the dairy, food, chemical, pharmaceutical,
Plus, you can test sample sizes as small as 3.4 oz
(100 ml) at adjustable pressures up to 29,008 psi cosmetic and biotech industries
(2,000 bar) – the highest pressure of any lab unit
available – for unmatched research flexibility and
cost efficiencies. LAB S E R I E S HOMOG E N I Z E R S
• Unique, knife-edge dual function homogenizing and cell disruption valve helps
Lab Series Homogenizers provide the desired mean deliver superior emulsions, dispersions or harvest of intracellular products
particle size and narrow, uniform distribution you • Available two-stage homogenizing valve can be specified in either tungsten
need to help you improve existing products and
carbide or ceramics
develop new ones.
• Features an easy-to-read digital pressure display and electronic pressure
safety system
• Small footprint – suitable for benchtop location
• Field-replaceable and reversible tungsten carbide pump valve seats
• Smooth, quiet and reliable operation
• Two units available to meet your laboratory requirements; operating pressures
SPX FLOW, Inc. (NYSE:FLOW) is a leading
of 14,504 psi (1,000 bar) and 29,008 psi (2,000 bar) with nominal capacities
manufacturer of innovative flow technologies,
many of which help define the industry standard of 6 gal/h (22 l/h) and 3 gal/h (11 l/h) respectively. Ideal for a wide variety of
in the market segments they serve. From its emulsions and dispersions and exits at a pressure sufficient for movement to
headquarters in Charlotte, North Carolina, it
the next processing stage.
operates a sales and support network, centers
of manufacturing excellence, and advanced
engineering facilities, throughout the world. Its Optional Equipment
cutting-edge flow components and process • Air operated pressure feeder assembly
equipment portfolio includes a wide range
• Explosion proof design
of pumps, valves, heat exchangers, mixers,
homogenizers, separators, filters, UHT, and drying • Two-stage homogenizing valve assembly
technology that meet many application needs. • Aseptic cylinder design
Its expert engineering capability also makes it a
• Digital gauge and gauge adapter for second stage pressure readout
premium supplier of customized solutions and
complete, turn-key packages to meet the most • Elastomers and wettables available in alternative material
exacting of installation demands.
T H E T H E O RY O F H O M O G E N I Z A R T I O N
To learn more about SPX FLOW capabilities,
its latest technology innovations and complete
service offerings, please visit www.spxflow.com.
2
T H E T H E O RY O F H O M O G E N I Z AT I O N
Typical Applications
The unhomogenized product (E) enters the valve seat (B) at Typical product applications
high pressure and low velocity. As the product flows through the
adjustable, close clearance area between the valve (A) and seat (B),
there is a rapid increase in velocity with a corresponding decrease in
pressure. Food/Benerage
Beverage emulsion
This intense energy transition, occurring in microseconds, produces
Fat substitutes
turbulent three-dimensional mixing layers that disrupt the particles
Milk
at the discharge from the gap (D). The homogenized product (F) Sauces
impinges on the impact ring (C) and exits at a pressure sufficient for
movement to the next processing stage. Personal care/Cosmetics
Hair products
Liposome emulsions
HOMOG E N I Z I NG TECH N IQU E S
Nail polish
Single-stage or two-stage homogenization: Skin creams
For processing of emulsions, a single-stage valve assembly may be
used; however, the use of a two-stage assembly, where approximately
Pharmaceutical/Biotech
10% of the total pressure is applied to the second stage, will improve Cell disruption
the droplet size reduction of most emulsions. Intravenous emulsions
Nutritional supplements
For processing dispersions, a single-stage valve assembly is usually
Ointments
preferred.
110
Relative Volume
7 Passes
60 60
30,000 psi (2068 bar)
10 Passes
50
40 40
30
20 20
10
0 0
0.00 0.10 0.20 0.30 0.40 0.50 0.60 0.70 50 100 200 500 1K 2K 5K
Premix Particle Diameter–Nanometers
Droplet Diameter (um) 3000 psi (207 bar)
10,000 psi (689 bar)
30,000 psi (2068 bar)
A B OV E : T H E E F F E CT O F U P TO 1 0 D I S C R E T E PA S S E S AT 1 4 5 0 4 p s i A B OV E : T H E R E D U CT I O N I N AV E R AG E PA R T I C L E S I Z E
( 1 0 0 0 b a r ) O N A N O I L - I N - WAT E R I N T R AV E N O U S E M U L S I O N . E AC H PA S S R E S U LT I N G F R O M H O M O G E N I S AT I O N AT VA R I O U S
R E S U LT S I N A S H I F T O F T H E PA R T I C L E S I Z E D I S T R I B U T I O N TOWA R D S PR E SSU R E S.
S MALLE R D ROPLET S I Z E S.
3
Lab Series
HOMOG E N I Z E R S
S TA N DA R D F E AT U R E S / E Q U I P M E N T M O D E L 10 0 0 MOD E L 2000
O - R I N G S / B AC K U P R I N G * EPDM/POM EPDM/POM
P U M P VA LV E S E AT M AT E R I A L * Tu n g s t e n C a r b i d e Tu n g s t e n C a r b i d e
H O M O G E N I S I N G VA LV E / S E AT * Ceramic Ceramic
D I G I TA L P R E S S U R E D I S P L AY Ye s Ye s
OV E R C U R R E N T P R E S S U R E S A F E T Y SYST E M Ye s Ye s
T E F C . 3 k W, t h r e e - p h a s e / 5 0 - 6 0 H z / T E F C . 3 k W, t h r e e - p h a s e / 5 0 - 6 0 H z /
M OTO R
2 0 0 , 2 3 0 , 3 8 0 , 4 0 0 , 4 6 0 , 5 7 5 Vo l t s 2 0 0 , 2 3 0 , 3 8 0 , 4 0 0 , 4 6 0 , 5 7 5 Vo l t s
* P V D F - P O LY V I N Y L I D E N E F L U O R I D E , E P D M - E T H Y L E N E P R O PY L E N E D I E N E M O N O M E R , P O M - AC E TA L P O LY M E R
SINGLE STAGE
N E T W E I G H T 2 3 1 l b ( 1 0 5 k g ) ∙ G R O S S W E I G H T 2 8 7 l b ( 1 3 0 k g ) ∙ VO L U M E 1 8 f t 3 ( 0 , 5 M 3 )
Based in Charlotte, North Carolina, SPX FLOW, Inc. (NYSE: FLOW) is a multi-industry manufacturing leader. For more information, please
visit www.spxflow.com
S PX F LOW
SPX FLOW, Inc. reserves the right to incorporate our latest design and material changes without notice or obligation.
Design features, materials of construction and dimensional data, as described in this bulletin, are provided for your information only and should not be relied upon unless confirmed
in writing. Please contact your local sales representative for product availability in your region. For more information visit www.spxflow.com.
The green “ ” and “ ” are trademarks of SPX FLOW, Inc.
ISSUED 10/2016 3003-03-08-2008-US
COPYRIGHT © 2016 SPX FLOW, Inc.