Supporting Information

Table S1. Equipment cost correlations and price data

Cost correlation log 10 C p =K 1+ K 2 log 10 A+ K 3 [log 10 A ]2 +log 10 F ¿p

Equipment K1 K2 K3
Compressor 2.2897 1.3604 -0.1027
Steam turbine drive* 2.6259 1.4398 -0.1776
Tower 3.4974 0.4485 0.1074
Trays 2.9949 0.4465 0.3961
Kettle reboiler 4.4646 -0.5277 0.3955
Heat Exchanger 4.8306 -0.8509 0.3187
Tank 3.4974 0.4485 0.1074
Pump 3.3892 0.0536 0.1538
Utility Cost ($/GJ)
Cooling water at 25 °C 0.378
High pressure steam 5.66
Cp: purchased cost of equipment; P: pressure; D: diameter; A: capacity parameter

#: Fp: pressure correction factor (1 for all equipment except tower and kettle reboiler)

PD
+ 0.00315
Tower: 2[850−0.6 P] ; Kettle reboiler:
F p=
0.0063
log 10 F p =0.03881−0.11272 log10 P+0.08183[log 10 P ]2

*: Fixed speed drive (FSD); Variable speed drive cost is twice FSD cost

Table S2. Composition controller parameters for candidate designs

Tuning parameters ΔP 0 bar ΔP 1bar ΔP 3bar ΔP 5 bar ΔP 7 bar
Distillate purity* 0.2 0.3 0.3 0.3 0.3
Kc (%/%) #
Bottom impurity 0.2 0.2 0.2 0.2 0.3
*
Distillate purity 100 150 100 100 100
τI (mins)
Bottom impurity# 450 450 300 250 350
 *: Sensor span: 0.98 – 0.999; Setpoint 0.99; MV: Reflux ratio; MV Span: 5-40 kmol/h
#: Sensor span: 0.005 – 0.08; Setpoint: 0.03; MV: Compressor dof; MV span: 0 – 100%