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Risk Factors: Genetic predisposit

Hypercholesterolemia
Men (>45 years old)
Women (>55 years old)
Cigarette smoking
cell membrane
Alcoholism
Diabetes mellitus
Obesity functional vasoconstri
Physical inability
↑ sodium intake*
Hereditary*

\
peripher

Predisposing Factors:
Hypertension* HPN
(↑ BP)

Vasoconstrictio n of blood

Vasoconstricti on of coronary ↑


Increase pressure of workloa

↑ force of LV
Injury of the endothelial vessel layer

↑ stress on the left ventricular

Vessel
↑ cardiac LV
Ventricular
Left ventricular Hypertroph
Monocytes, platelets,cholesterol and other blood

Scarrin
↓ Brain perfusion: dizziness, light headedness, confusion, anxiety, restlessness
Atherosclerosis
. ↓Response to energy demands causing easily
↓ left
ventricular
CA

↑ residual blood of the LV at the time of


↓ cardiac tissue

↑ LV
↓ cardiac muscle

blood backflows
↓ Cardiac
Activation of baroreceptors in the LV, aortic
{ ↓ Systemic blood ↑ residual blood of the LA during

Stimulation of vasomotor regulatory


↓ Perfusion of tissues of the
↑ LA

Activation of sympathetic nervous ↓GFR ↓


blood returns to pulmonary
Renal

Proteinu ria, Reni


↑ urea (8.0), ↓ Accumulation of blood in the pulmonary
↑ catecolami nes
formation of

(Lung s)

Angiotensin
Hypothala
Sodium and Water
ADH Pulmonary
edema:
dyspnea, cough,
crackles, 2 pillow
↓ urine ↑osmo
tic

Pulmonary
↓ urine ↑osmo
edema:
tic
dyspnea, cough,
crackles, 2 pillow
HR

↑ pulmonary ↓O2 saturation


vascular

↑ RV
contract

↑ force
of RV

↑ RV RV
oxygen

↓ force of RV

↑ residual blood of the RV at the

↑ RV

blood backflows

Peripheral edema, liver congestion, ascites, weakness, weight gain due

↑ RA

↑ RA

↑ venous pressure JVD blood backflows from RA to


↑ fluid moves into the

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