 Antipsychotics

Name of Dosage, Indicati Mechanism Contrain Adverse Nursing responsibility

drug route, on of action dication effects
frequenc
y
Generic PO 2–3 Treatm Mechanism Hyperse Body as a BEFORE:
Name: mg once ent of is not well nsitivity Whole: -Reassess patients
Risperid daily for bipolar understood. to Orthostatic periodically and maintain
one up to 3 disorde Interferes risperido hypotension on the lowest effective
wk r. with binding ne. with initial drug dose.
Brand of dopamine Brain doses, -Monitor cardiovascular
Name: to D2- tumor, sweating status closely
Risperda interlimbic severe CNS: -Monitor periodically
l region of the CNS Sedation, blood glucose, serum
brain, depressi drowsiness, electrolytes, liver function,
Therape serotonin (5- on, head headache and complete blood
utic HT2) trauma; CV: counts.
Classifi receptors, suicidal Prolonged DURING:
cation: and alpha- ideation, QTc interval, -Note that quick-
Antipsyc adrenergic tardive tachycardia dissolving tablets dissolve
hotic receptors in dyskinesi GI: Dry rapidly when placed on
the occipital a; mouth, tongue.
cortex. It has sunlight dyspepsia -Do not exceed
low to (UV) Endocrine: increases/decreases of 1
moderate exposure Galactorrhea mg b.i.d. in normal
affinity for the , tanning Metabolic: populations.
other beds; Hyperglycem -Store at 15°–30° C (59°–
serotonin (5- pregnanc ia 86° F).
HT) y Respiratory: AFTER:
receptors (category Rhinitis, Patient & Family Education
and no C), cough, -Carefully monitor blood
affinity to lactation, dyspnea. glucose levels if diabetic.
nondopamine c Skin: -Do not engage in
rgic sites Photosensitiv potentially hazardous
(e.g., ity. activities until the
cholinergic, Urogenital: response to drug is
muscarinic, Urinary known.
or beta- retention -Wear sunscreen and
adrenergic protective clothing to
receptors). avoid photosensitivity.
Name of Dosage, Indicati Mechanism Contrain Adverse Nursing responsibility
drug route, on of action dication effects
frequenc
y
Generic PO with Treatm Unrelated to Hyperse Body as a BEFORE:
Name: 40 mg ent of phenothiazin nsitivity Whole: -Lab tests: Baseline and
Ziprasid b.i.d. acute e or to Asthenia, periodic ECG, serum
one bipolar butrophenon ziprasido myalgia, potassium and serum
Hydrochl mania. e ne; weight gain magnesium, especially
oride antipsychotic history of CNS: with concomitant diuretic
agents. QT Somnolence, therapy. Periodically
Brand Exhibits high prolongat akathisia monitor blood glucose.
Name: in vitro ion GI: Nausea, -Monitor I&O ratio and
Geodon binding including constipation, pattern
affinity for the congenit dyspepsia -Monitor BP lying, sitting,
Therape following al long Metabolic: and standing
utic receptors: QT Hyperglycem -Monitor cognitive status
Classifi dopamine D2 syndrom ia, diabetes and take appropriate
cation: and D3, e or with mellitus. precautions.
Antipsyc serotonin other Respiratory: -Monitor for loss of
hotic 5HT2A, drugs Rhinitis, seizure control
5HT2C, known to increased DURING:
5HT1A, prolong cough, -Give with food.
5HT1D, and the QT dyspnea -Make dosage
the alpha-1- interval; Skin: Rash, adjustments at intervals
adrenergic AV fungal of 2 d.
receptors, block, dermatitis, AFTER:
and bundle photosensitiv Patient & Family Education
moderate branch ity -Be aware that
affinity for the block, Special therapeutic effect may not
histamine H1 cardiac Senses: be evident for several
receptor. arrhythmi Abnormal weeks.
as, vision. -Do not drive or engage
congenit in potentially hazardous
al heart activities until response to
disease drug is known.
-Make position changes
slowly and in stages to
prevent dizziness upon
arising.
-Avoid strenuous
exercise,

REFERENCES:
Risperidone. (n.d.). Welcome to RobHolland.com – Rob Holland's Personal Webspace and
Online Notebook.
https://robholland.com/Nursing/Drug_Guide/data/monographframes/R023.html
Ziprasidone hydrochloride. (n.d.). Welcome to RobHolland.com – Rob Holland's Personal
Webspace and Online Notebook.
https://www.robholland.com/Nursing/Drug_Guide/data/monographframes/Z008.html