READING

Name : 1. Muhammad Bonamirza Syafrullah

2. Abel Triyanti

NUTRITION B

POLTEKKES KEMENKES PALEMBANG

ACADEMIC YEAR 2021-2022

VITAMIN B6 OR PYRIDOXINE
 Vitamin B6 or pyridoxine is a substance that functions as an essential nutrient in the
body and plays a role in the balance of the body's metabolism. This drug is often used in the
management of vitamin B6 deficiency, sideroblastic anemia, and prophylaxis of peripheral
neuropathy. Vitamin B6 has the chemical name hydroxymethylpyridine which is a group of
hydroxymethyl. The chemical formula of vitamin B6 is C8H11NO3.

Vitamin B6 is a water soluble vitamin. This vitamin is found naturally in various

foods. Vitamin B6 consists of 6 active metabolites, namely vitamin B6, pyridoxal,
pyridoxamine, and phosphorylated derivatives, namely vitamin B6-5-phosphate, pyridoxal-5-
phosphate, and pyridoxamine-5-phosphate.

Generally, vitamin B6 is used in the management of vitamin B6 deficiency and

prophylaxis for peripheral neuropathy, especially for tuberculosis patients who regularly take
isoniazid. In addition, vitamin B6 is also often used in the treatment of hyperemesis
gravidarum and sideroblastic anemia.

In several studies, it was found that vitamin B6 has benefits for maintaining heart
health, namely by maintaining blood pressure and has been shown to prevent platelet
aggregation, reduce LDL cholesterol levels, and increase HDL cholesterol.

TRANSLETE

Vitamin B6 atau piridoksin adalah zat yang berfungsi sebagai nutrisi esensial dalam tubuh
dan berperan dalam keseimbangan metabolisme tubuh. Obat ini sering digunakan dalam tata
laksana defisiensi vitamin B6, anemia sideroblastik, serta profilaksis neuropati perifer.
Vitamin B6 memiliki nama kimia hidroksimetilpiridin yang merupakan grup dari
hidroksimetil. Rumus kimia dari vitamin B6 adalah C8H11NO3.

Vitamin B6 merupakan vitamin yang larut air. Vitamin ini terkandung secara natural di dalam
berbagai makanan. Vitamin B6 terdiri dari 6 metabolit aktif yaitu vitamin B6, piridoksal,
piridoksamin, dan turunan hasil fosforilasi yaitu vitamin B6-5-fosfat, piridoksal-5-fosfat, dan
piridoksamin-5-fosfat.

Umumnya vitamin B6 digunakan dalam tata laksana defisiensi vitamin B6 dan profilaksis
untuk neuropati perifer, khususnya bagi penderita tuberkulosis yang rutin mengonsumsi
isoniazid. Selain itu, vitamin B6 juga sering digunakan dalam terapi hiperemesis gravidarum
dan anemia sideroblastik.

Pada beberapa penelitian, didapatkan bahwa vitamin B6 memiliki manfaat untuk menjaga
kesehatan jantung, yaitu dengan menjaga tekanan darah dan terbukti dapat mencegah
terjadinya agregasi platelet, menurunkan kadar kolesterol LDL, dan meningkatkan kolesterol
HDL.

This research aimed to study Piridoksin (Vitamin B6) status in blood sample of Attention Deficit.
Uinsu article by Ms.Batubara

New vocabulary of our can find here :

 chemical : bahan kimia
 soluble : Larut
 various : bermacam-macam
  Generally: umumnya
 especially: khususnya
 several : beberapa
 maintaining:menjaga
 prevent : mencegah
 aggregation : pengumpulan

The example :
 what the meaning of Vitamin B6 or pyridoxine ?
the meaning of Vitamin B6 or pyridoxine is a substance that functions as an essential nutrient
in the body and plays a role in the balance of the body's metabolism.

 what do you know about pyridoxine ?

This drug is often used in the management of vitamin B6 deficiency, sideroblastic anemia,
and prophylaxis of peripheral neuropathy.

 what the name of chemical formula ?

The name of chemical formula of vitamin B6 is C8H11NO3.

 when vitamin B6 is also often used ?

vitamin B6 is also often used in the treatment of hyperemesis gravidarum and sideroblastic
anemia.

 how you know vitamin B6 or pyridoxine has maintaining benefit ?

it was found that vitamin B6 has benefits for maintaining heart health, namely by
maintaining blood pressure and has been shown to prevent platelet aggregation, reduce LDL
cholesterol levels, and increase HDL cholesterol.