Name of Drug Dosage, Mechanism of Indication Contraindication Adverse Effect Nursing Responsibilities

Frequency, Action
Route, Timing

Generic Name Dosage: Binds to bacterial cell Treatment of susceptible History of hypersensitivity/ Frequent: BASELINE ASSESSMENT
Cefuroxime Axetil 500 mg membranes, inhibits infections due to group B anaphylactic reaction to Oral candidiasis (thrush), • Obtain CBC, renal function tests.
cell wall synthesis. streptococci, pneumococci, cefuroxime, mild diarrhea, mild • Question for history of allergies, particularly
Brand Names Frequency: BID staphylococci, H. influenzae, cephalosporins. abdominal cramping cephalosporins, penicillins.
Zinnat Therapeutic Effect: E. coli, Enterobacter,
Route: Bactericidal. Klebsiella, including Occasional: INTERVENTION/EVALUATION
Classification PO acute/chronic bronchitis, Nausea, serum • Assess oral cavity for white patches on
Antiobiotic gonorrhea, impetigo, early sickness–like reaction mucous membranes, tongue (thrush).
Timing: Lyme disease, otitis media, (fever, joint • Monitor daily pattern of bowel activity, stool
Not an OTC drug. It is 8AM, 8PM pharyngitis/tonsillitis, sinusitis, pain; usually occurs after consistency. Mild GI effects may be tolerable
prescribed by a doctor or skin/skin structure, UTI, second course of therapy (increasing severity may indicate onset of
other health care perioperative prophylaxis. and resolves after drug is antibiotic-associated colitis).
professional. discontinued). • Monitor I&O, renal function tests for
nephrotoxicity.
Rare: • Be alert for superinfection: fever, vomiting,
Allergic reaction (rash, diarrhea, anal/genital pruritus, oral mucosal
pruritus, urticaria), changes (ulceration, pain, erythema).

PATIENT/FAMILY TEACHING
• Doses should be evenly spaced.
• Continue antibiotic therapy for full length of
treatment.
• May cause GI upset (may take with food,
milk).