Ixodes scapularis (Deer tick)

Echinococcus multilocularis
Amblyomma americanum
Rhipicephalus sanguineus

Echinococcus granulosus
Amblyomma maculatum

Ancylostoma braziliense
Insect growth regulator*

Uncinaria stenocephala
(Western black-legged)
Dermacentor variabilis

Ancylostoma caninum
A Practitioner’s Quick Reference to Selected

Dipylidium caninum
(American dog tick)

Cheyletiella yasguri

Sarcoptes scabiei**
Toxascaris leonina

Otodectes cynotis
Dogs

Roundworms
Dirofilaria immitis
ParaSiticides

Heartworms

Chewing Lice
Taenia pisiformis
(Brown dog tick)

Hookworms
Ixodes pacificus

Demodex canis
MOSQUITOES
(Gulf coast tick)

Whipworms
Toxocara canis

Tapeworms
(Lone star tick)

Trichuris vulpis
Unspecified

Unspecified
Adulticide*
FLEAS

Mites
TICKS
Product Min. age/ Administration
(Company [A.H. = animal health]), website Active Ingredients weight type/freq.
Activyl for Dogs (Merck A.H.) us.activyl.com Indoxacarb 8 wks/> 4 lb Topical/monthly ●***

Activyl Tick Plus for Dogs (Merck A.H.) us.activyl.com Indoxacarb, permethrin 8 wks/> 4 lb Topical/monthly ●*** ● ● ● ●

Advantage II for Dogs (Bayer A.H.) bayerdvm.com Imidacloprid, pyriproxyfen 7 wks Topical/monthly ● ● ●

Advantage Multi for Dogs (Bayer A.H.) bayerdvm.com Imidacloprid, moxidectin 7 wks/> 3 lb Topical/monthly ● ● ● ● ● ● ●

Capstar (Novartis A.H.) capstarpet.com Nitenpyram 4 wks/> 2 lb Oral tablet/single dose ●

Topical/can be applied every

Fipronil, (S)-methoprene,
Certifect (Merial) certifect.com 8 wks/5 lb 3 mos for fleas; ticks and lice ● ● ● ● ● ● ● ● ● ●
amitraz monthly applications
Cestex (Zoetis) zoetis.com Epsiprantel 7 wks Oral tablet ● ●

Comfortis (Elanco) comfortis.com Spinosad 14 wks/3.3 lb Oral tablet/monthly ●

Drontal Plus; Drontal Taste Tabs (Bayer A.H.) Praziquantel, pyrantel 3 wks/> 2 lb Oral tablet ● ● ● ● ● ● ● ● ●
bayerdvm.com pamoate, febantel
EFFITIX Topical Solution for Dogs (Virbac A.H.) ●**
Fipronil, permethrin 12 wks Topical/monthly ● ● ● ● ● ● ●
virbacvet.com/products
Topical/can be applied every
Frontline Plus for Dogs (Merial) frontline.com Fipronil, (S)-methoprene 8 wks 3 mos for fleas; ticks and lice ● ● ● ● ● ● ● ●
monthly applications
Frontline Tritak for Dogs† (Merial) Fipronil, cyphenothrin, 12 wks/4 lb Topical/monthly ● ● ● ● ●
frontlinetritak.com (S)-methoprene
Heartgard Chewables (Merial) heartgard.com Ivermectin 6 wks Chewable tablet/monthly ●

Heartgard Plus (Merial) heartgard.com Ivermectin, pyrantel 6 wks Chewable tablet/monthly ● ● ● ● ● ●

Iverhart Max Chewable Tablets (Virbac A.H.) Ivermectin, pyrantel
virbacvet.com/products pamoate, praziquantel
Iverhart Plus Flavored Chewables (Virbac A.H.) Ivermectin, pyrantel
virbacvet.com/products pamoate
Imidacloprid, permethrin,
K9 Advantix II (Bayer A.H.) bayerdvm.com
pyriproxyfen
Mitaban (Zoetis) zoetis.com Amitraz
Nemex (Zoetis) zoetis.com Pyrantel pamoate
Ovitrol X-Tend Flea & Tick Spot On for Dogs (VPL) Etofenprox, (S)-metho-
ovitrolxtend.com prene, piperonyl butoxide
Panacur C (Merck A.H.) merck-animal-health-usa.com Fenbendazole
Parastar (Novartis A.H.) parastarpet.com Fipronil
8 wks Chewable tablet/monthly ● ● ● ● ● ● ● ●
6 wks Chewable tablet/monthly ● ● ● ● ● ●
7 wks Topical/monthly ● ● ● ● ● ● ● ●
Safety not Topical liquid, diluted and
demonstrated in ●
applied/3 to 6 treatments
dogs < 4 mos
Oral tablet or oral suspension/
2 wks every 2 wks for puppies to 10 wks; ● ● ● ●
adults treat until negative fecal
10 wks Topical/monthly ● ● ● ●
Oral granules given three
6 wks ● ● ● ● ● ●
consecutive days
8 wks Topical/monthly ● ● ● ● ● ● ●

Parastar Plus (Novartis A.H.) parastarpluspet.com Fipronil, cyphenothrin 12 wks Topical/monthly ● ● ● ● ● ● ●

Powerband (VPL) vetkem.com Propoxur, (S)-methoprene 12 wks Collar/5 mos ● ● ●

Preventic (Virbac A.H.) virbacvet.com/products Amitraz 12 wks Collar/90 days ●

Program Flavor Tabs (Novartis A.H.) Lufenuron 4 wks Oral tablet/monthly ●

program.novartis.us
ProHeart 6 (Zoetis) zoetis.com Moxidectin 6 mos Subcutaneous injection/6 mos ● ● ●

ProTICall Insecticide for Dogs (Merck A.H.) Permethrin 4 wks Topical/monthly ● ● ● ● ● ● ● ●

merck-animal-health-usa.com
Pyrethrin, piperonyl
Pyrethrin Dip Anti-Parasitic (Virbac A.H.) Topical/do not use more than
butoxide, N-octyl bicyclo- 12 wks ● ● ● ●
virbacvet.com/products once every 7 days
heptene dicarboximide
Resultix (Bayer A.H.) bayerdvm.com Isopropyl myristate Topical/use as needed to kill ticks ●

Revolution (Zoetis) revolution4dogs.com Selamectin 6 wks Topical/monthly ● ● ● ● ●

Safe-Guard Canine Dewormer (Merck A.H.) Oral granules given three

Fenbendazole 6 wks ● ● ● ● ● ●
safe-guard-for-dogs.com consecutive days
Scalibor Protector Band for Dogs (Merck A.H.) †† ‡
Deltamethrin 12 wks Collar/6 mos ● ● ● ● ● ● ●
scalibor-usa.com
Milbemycin oxime,
Sentinel Flavor Tabs (Novartis A.H.) sentinelpet.com 4 wks/> 2 lb Oral tablet/monthly ● ● ● ● ● ●
lufenuron
Seresto (Bayer A.H.) bayerdvm.com Flumethrin, imidacloprid 7 wks/> 18 lb Collar/8 mos ● ● ● ● ● ● ●

Spinosad, milbemycin
Trifexis (Elanco) trifexis.com 8 wks/5 lb Oral tablet/monthly ● ● ● ● ● ●
oxime
Tri-Heart Plus Chewable Tablets (Merck A.H.) Ivermectin, pyrantel 6 wks Chewable tablet/monthly ● ● ● ● ● ●
triheartplus.com pamoate
Dinotefuran, permethrin,
Vectra 3D (Ceva A.H.) vectrapet.com 7 wks Topical/monthly ● ● ● ● ● ● ● ● ● ● ●
pyriproxyfen
Vectra for Dogs and Puppies (Ceva A.H.) Dinotefuran, pyriproxyfen 8 wks Topical/monthly ● ●
vectrapet.com
Virbantel Flavor Chewables (Virbac A.H.) Pyrantel pamoate/ Chewable tablet/as needed to
12 wks/> 6 lb ● ● ● ● ● ● ●
virbacvet.com/products praziquantel eliminate/control parasites
*See product label or insert for information about activity against any other flea life stages, or contact the product manufacturer.
**See product label or insert.
***The manufacturer (Merck A.H.) notes that the EPA-approved label indicates flea larvicidal activity.
Amblyomma americanum
Rhipicephalus sanguineus

Ancylostoma tubaeforme

†
Not available in all U.S. states.
Ancylostoma braziliense
Insect growth regulator*

††
Dermacentor variabilis

The manufacturer (Merck A.H.) notes that the EPA-approved label indicates the product kills A. americanum.
‡
The manufacturer (Merck A.H.) notes that the EPA-approved label indicates anti-mosquito activity. Taenia taeniaeformis
Dipylidium caninum
(American dog tick)

Sarcoptes scabiei**
Otodectes cynotis
Roundworms
Dirofilaria immitis
Ixodes scapularis

Heartworms

Chewing Lice
(Brown dog tick)

Hookworms
MosquitoEs

Cats
Tapeworms
(Lone star tick)

Toxocara cati
Unspecified
Adulticide*

(Deer tick)
FleaS

Mites
Ticks

Product (Company [A.H. = animal health]), website Active Ingredients Min. age/weight Administration type/freq.
Activyl for Cats (Merck A.H.) us.activyl.com Indoxacarb 8 wks/> 2 lb Topical/monthly ●***

Advantage II for Cats (Bayer A.H.) bayerdvm.com Imidacloprid, pyriproxyfen 8 wks Topical/monthly ● ●

Advantage Multi for Cats (Bayer A.H.) bayerdvm.com Imidacloprid, moxidectin 9 wks/> 2 lb Topical/monthly ● ● ● ● ●

Assurity (Elanco) assurity4cats.com Spinetoram 8 wks Topical/monthly ●

Breakaway Plus (VPL) vetkem.com Propoxur, (S)-methoprene 12 wks Collar/8 mos for fleas/6 mos for ticks ● ● ●

Capstar (Novartis A.H.) capstarpet.com Nitenpyram 4 wks/> 2 lb Oral tablet/single dose ●

Cestex (Zoetis) zoetis.com Epsiprantel 7 wks Oral tablet ● ●

Comfortis (Elanco) comfortis.com Spinosad 14 wks/2 lb Oral tablet/monthly ●

Droncit Feline Cestocide Tablets (Bayer A.H.) bayerdvm.com Praziquantel 6 wks Oral tablet ● ●

Drontal Tablets (Bayer A.H.) bayerdvm.com Praziquantel, pyrantel pamoate 8 wks/2 lb Oral tablet ● ● ● ●

EasySpot (Novartis A.H.) easyspotpet.com Fipronil 8 wks Topical/monthly ● ● ● ● ● ●

Topical/6 wks/monthly recommended

EFFIPRO Topical Solution for Cats (Virbac A.H.) virbacvet.com/products Fipronil 8 wks ● ● ● ● ● ● ●
for FAD and tick prevention
Topical/can be applied every 3 mos for
Frontline Plus for Cats (Merial) frontline.com Fipronil, (S)-methoprene 8 wks ● ● ● ● ● ● ●
fleas; ticks and lice monthly applications
Frontline Tritak for Cats† (Merial) frontlinetritak.com Fipronil, etofenprox, (S)-methoprene 12 wks Topical/monthly ● ● ● ●

Heartgard Chewables for Cats (Merial) heartgard.com Ivermectin 6 wks Chewable tablet/monthly ● ● ●

Ovitrol X-Tend Flea & Tick Spot On for Cats (VPL) ovitrolxtend.com Etofenprox, (S)-methoprene 12 wks Topical/monthly ● ● ● ●

Topical/if reinfection occurs, product can be

Profender (Bayer A.H.) profender.com/products Emodepside, praziquantel 8 wks/2.2 lb ● ● ● ●
reapplied in 30 days
Program 6-month Injectable for Cats (Novartis A.H.) program.novartis.us Lufenuron 6 wks Subcutaneous injection/6 mos ●

Program Flavor Tabs (Novartis A.H.) program.novartis.us Lufenuron 4 wks Oral tablet/monthly ●

Program Suspension (Novartis A.H.) program.novartis.us Lufenuron 6 wks Oral liquid/monthly ●

Pyrethrin, piperonyl butoxide, N-octyl Topical/do not use more than once
Pyrethrin Dip Anti-Parasitic (Virbac A.H.) virbacvet.com/products 12 wks ● ● ● ●
bicycloheptene dicarboximide every 7 days
Resultix (Bayer A.H.) bayerdvm.com Isopropyl myristate Topical/use as needed to kill ticks ●

Revolution (Zoetis) revolution4cats.com Selamectin 8 wks Topical/monthly ● ● ● ● ●

Seresto (Bayer A.H.) bayerdvm.com Flumethrin, imidacloprid 10 wks Collar/8 mos ● ● ● ● ● ●

Vectra for Cats and Kittens (Ceva A.H.) vectrapet.com Dinotefuran, pyriproxyfen 8 wks Topical/monthly ● ●

*See product label or insert for information about activity against any other flea life stages, or contact the product manufacturer.
**See product label or insert. This quick reference poster is a summary only and is not intended to contain a and usage information. This poster contains selected parasiticides available in the
***The manufacturer (Merck A.H.) notes that the EPA-approved label indicates flea larvicidal activity.
†
comprehensive listing of all indications. Readers are responsible for reading and United States and is not intended to be a complete listing of all parasiticides available
Not available in all U.S. states.
becoming familiar with the individual product inserts and labels for complete indications to veterinarians and the public.