DRUG STUDY

Name of the Patient : Patient M Age : 2 years old and 9 months Sex : Female Name of Student: Lian Robbie R. Bautista
Civil Status : _______________Religion : Roman Catholic Rm/Bed No. _________________ Area : __________________________ Level/ Block : II- A
Address : Pulilan. Bulacan Date Submitted : ___________________________________________
Date of Admission: February 3, 2011 Diagnosis : Bronchitis Rating : ___________________________________________________

MEDICATION Classification/ Action
Generic name: Classification:
ibuprofen Chemical class: Propionic acid
derivative
Therapeutic class: Analgesic,
Brand name: antiinflammatory,
Dolan antipyretic
Usual dosage/ Mechanism of Action:
frequency: Blocks activity of
cyclooxygenase, the enzyme
 To reduce needed to synthesize
fever prostaglandins, which mediate
inflammatory response and
CAPSULES, cause local vasodilation,
CHEWABLE swelling, and pain. By inhibiting
TABLETS, ORAL prostaglandins, this NSAID
SUSPENSION, reduces inflammatory
TABLETS symptoms and relieves pain.
Children ages 6
months to 12 years. 5 Ibuprofen’s antipyretic action
to10 mg/kg every 4 to probably stems from its effect
6 hr.  on the hypothalamus, which
Maximum: 40 mg/ kg increases peripheral blood
daily.
Indications Contraindications Side Effects Adverse Effects Nursing Responsibilities
 To relieve pain in Angioedema, asthma, Occasional CNS: Aseptic meningitis, Prior:
rheumatoid arthritis and bronchospasm, nasal (9%–3%): dizziness, headache, • Verify the doctor’s order regarding
osteoarthritis, mild to polyps, rhinitis, or Nausea, nervousness, seizures, the medication as well as the
moderate pain, acute urticaria caused by vomiting, stroke patient’s identity. 
migraine pain, pain in hypersensitivity to dyspepsia, CV: Fluid retention, heart • Double check the name and
primary dysmenorrhea, aspirin, ibuprofen, dizziness, rash.  failure, hypertension, MI, expiration date of the medication
minor aches, iodides, or other peripheral edema, • Obtain the past health history of
dysmenorrhea, pain in NSAIDs; perioperative Rare (less tachycardia the patient.
juvenile arthritis, pain with coronary than 3%): EENT: Amblyopia,
moderate to severe pain artery bypass graft Diarrhea or epistaxis, stomatitis, During:
as an adjunct to opioid surgery constipation, tinnitus • Explain to the significant others the
analgesics flatulence, GI: Abdominal cramps, effect of the drug to his body
 To reduce fever abdominal distention, or pain; • Monitor liver function test results
cramps or pain, anorexia; constipation; because, in rare cases, elevations
pruritus, diarrhea; diverticulitis; may progress to severe hepatic
increased B/P. dyspepsia; dysphagia; reactions, including fatal hepatitis,
elevated liver function liver necrosis, and hepatic failure.
test results; epigastric • Monitor BUN and serum creatinine
discomfort; esophagitis; levels in elderly patients, patients
flatulence; gastritis; taking diuretics or ACE inhibitors,
gastroenteritis; and patients with heart failure,
gastroesophageal reflux impaired renal function, or hepatic
disease; GI bleeding, dysfunction; drug may cause renal
hemorrhage, perforation, failure.
 flow, causing vasodilation and or ulceration; heartburn;
encouraging heat dissipation. hemorrhoids; hepatic
Usual route: failure; hepatitis; hiatal
Per Orem hernia; indigestion;
melena; nausea;
stomatitis; vomiting
GU: Cystitis, hematuria,
renal failure (acute)
HEME: Agranulocytosis,
Drug order: anemia, aplastic anemia,
Dolan 5 ml for body eosinophilia, hemolytic
temperature of 38'C anemia, leukopenia,
and above  neutropenia,
pancytopenia, prolonged
bleeding time,
thrombocytopenia
RESP: Bronchospasm,
dyspnea, wheezing
SKIN: Blisters, erythema
multiforme,
photosensitivity, pruritus,
rash, Stevens- Johnson
syndrome, toxic
epidermal necrolysis,
urticaria
Other: Anaphylaxis,
angioedema, flulike
symptoms, hypokalemia,
weight gain
• Monitor CBC for decreased
hemoglobin and hematocrit. Drug
may worsen anemia.
• Assess patient’s skin regularly for
signs of rash or other
hypersensitivity reaction because
ibuprofen is an NSAID and may
cause serious skin reactions without
warning, even in patients with no
history of NSAID sensitivity. At first
sign of reaction, stop drug and notify
prescriber.
After: 
• Advise significant others to take
drug with food or after meals to
reduce GI distress.
• Advise patient’s significant others
to report flulike symptoms, rash,
signs of GI bleeding, swelling, vision
changes, and weight gain.
• Urge parents to tell prescriber
promptly if child receiving drug
develops a severe or persistent sore
throat, high fever, headache,
persistent diarrhea, nausea, or
vomiting or hasn’t been drinking
fluids.
• Advise parents to consult
prescriber before giving OTC
ibuprofen to a child if the child has
asthma, ulcers, bleeding problems,
high blood pressure, heart or kidney
disease, a need for diuretic therapy,
serious adverse effects from
previous use of fever reducers or
pain relievers, or persistent stomach
problems, such as heartburn, upset
stomach, or stomach pain.
• Explain that ibuprofen may
increase risk of serious adverse
cardiovascular reactions; urge
patient to seek immediate medical
attention if signs or symptoms arise,
such as chest pain, shortness of
breath, weakness, and slurring of
speech.
• Explain that ibuprofen may
increase risk of serious adverse GI
reactions; stress importance of
seeking immediate medical attention
for such signs and symptoms as
epigastric or abdominal pain,
indigestion, black or tarry stools, or
vomiting blood or material that looks
like coffee grounds.
• Alert patient’s significant others to
rare but serious skin reactions. Urge
him to seek immediate medical
attention for rash, blisters, itching,
fever, or other indications of
hypersensitivity.
• Document the assessment on the
patient (if there are unusual/side or
adverse effects occurs and the
likes).