DRUG STUDY

BSN2H-2D
Salang-Oy, Zayne
Baniaga, Oloan Richelle Joy

DRUG NAME MECHANISM OF ACTION INDICATION / ADVERSE EFFECT NURSING RESPONSIBILITIES

CONTRAINDICATION

GENERIC: ● Inhibits bacterial cell-wall INDICATIONS: CNS: BEFORE:

MEROPENEM
BRAND:
MERREM
THERAPEUTIC CLASS:
ANTI-INFECTIVE
PHARMACOLOGIC CLASS:
CARBAPENEM
DOSAGE:
● Children weighing 50 kg
(110 lb) or more: 1g
● Children ages 3 months
and older weighing less
than 50 kg (110 lb): 20
synthesis and penetrates
gram-negative and gram- ● Intra-abdominal infections.
positive bacteria.
● Bacterial meningitis.
SOURCE:
● Complicated skin and skin
Schull, P.D (2013) Nurse's Drug- structure infections.
Handbook. Retrieved from
CONTRAINDICATION:
https://www.google.com/amp/s/book
tree.ng/mcgraw-hill-nurses-drug- ● Hypersensitivity to drug, its
handbook-seventh-edition/amp/
components, or other beta-
lactams.
DRUG TO DRUG
INTERACTION:
● Probenecid: increased
meropenem blood level.
DRUG TO FOOD
INTERACTION:
● Headache, insomnia,
dizziness, drowsiness,
weakness, seizures.
CV:
● hypotension, phlebitis,
palpitations, heart failure,
cardiac arrest, myocardial
infarction.
GI:
● Nausea, vomiting, diarrhea,
constipation, tongue
discoloration, oral
candidiasis, glossitis.
pseudomembranous colitis.
GU:
Dx:
Monitor for the vital signs of the
patient.
Tx:
Perform C and S test prior to
therapy.
EDx:
Educate the patient not to breast feed
while using this drug.
Teach the patient on the proper way
of injecting.
Educate the patient to avoid driving
or doing tasks that required you to
be alert.
 mg/kg No interactions found. ● Hematologic: anemia,
eosinophilia, leukopenia,
● Children weighing 50 kg bone marrow depression,
(110 lb) or more: 2g thrombocytopenia,
neutropenia
● Children ages 3 month
and older weighing less ● Musculoskeletal:
than 50 kg (110 lb): 40 myoclonus
mg/kg
● Respiratory: chest
ROUTE: discomfort, dyspnea,
hyperventilation
INTRAVASCULAR (IV)
● Skin: rash, urticaria,
pruritus, erythema at
injection site
Other: altered taste, fever, pain,
fungal infection, anaphylaxis
DURING:
Dx:
Assess dizziness that might affect
gait, balance and other functional
activities.
Monitor for seizures especially in
older adults and those with renal
insufficiency.
Assess for signs of renal, hepatic or
haematological dysfunction.
Tx:
Provide therapeutic and non
therapeutic care to the patient.
EDx:
Educate the patient not to
AFTER:
Dx:
Monitor any signs of allergic
reactions and anaphylaxis.
Monitor injection site for pain,
swelling and irritation.

Tx:

Provide therapeutic and non

therapeutic care to the patient.

EDx:

Instruct children and family,

caregiver to report any signs of
thrust and moniliasis.

Instruct patients and family to report

other troublesome side effects of the
drug.
As a future nurses, would you recommend these drugs to your patient? Enumerate the pros and cons

As a future nurse, yes we would recommend it to our patients as given that we discussed its side and adverse effects and the patient understood it well. Its pros is can treat serious infections, able
to kill bacteria that are resistance to other antibiotics, has mild side effects for most, safe to use if you have liver problems, available as generic, can be used in newborns for certain infections if
needed and doesn’t have many drug interactions. For its cons are only available as an injection, if you have to take it at home, your provider has to insert a small tube in your skin and either you or
a nurse have to inject the medication, if you’re allergic to penicillin’s/ cephalosporin antibiotics you might not be able to use this medication, in people with kidney problem, your dose will need to
be adjusted and can raise the risk of seizures for some people, usually given 3 time a day.

BSN2H-2D
Washington, Luis

De Castro, Fiona

DRUG NAME MECHANISM OF ACTION INDICATION / CONTRAINDICATION ADVERSE EFFECT NURSING

RESPONSIBILITIES

GENERIC: INDICATIONs: Central Nervous System BEFORE:

ALBENDAZOLE Albendazole is found to inhibit the Prescribed for tapeworm infections, hydatid cyst Dx:
polymerization of  the parasite tubulin into disease, cysticercosis or neurocysticercosis,
BRAND: microtubules.  There is a higher affinity of capillariasis, cutaneous larva migrans, giardiasis, Headache, seizures, a. Observed the 10
albendazole to the parasite tubulin and so microsporidiosis including Septata intestinalis confusion, raised Rights before
ALBENZA the activity is mediated mainly against the infection, intestinal parasites in immigrants, intracranial pressure, administering
parasite rather than on the host. The loss of strongyloidiasis, trichinosis, trichostrongyliasis. It dizziness/vertigo, signs that medication.
the cytoplasmic microtubules leads to works by killing sensitive parasites meningeal sings.
impaired uptake of glucose by the larval b. Assessed for history
CLASSIFICATION: of seizure disorders.
and adult stages of the parasites. The worm
ANTHELMINTICS is then unable to maintain energy
CONTRAINDICATION:  Skin c. Checked for allergies.
production, which leads to immobilization
and eventual death. A secondary action of Reversible hair loss, d. Assessed baseline
Allergy to any ingredient in albendazole or to
albendazole may be the inhibition of the infection, hypersensitivity mental status
benzimidazoles
enzyme fumarate reductase, which is including rash and hives,
helminth-specific allergic reactions. Tx:
DOSAGE:
DRUG TO DRUG INTERACTION: a. Crushed tablets in
400mg
young children to be
 Gastrointestinal chewed and
swallowed with glass
ROUTE: Cimetidine Abdominal pain, of water.
nausea/vomiting.
SOURCE: In patients with hydatid cyst, albendazole
Oral b. Performed a
sulfoxide concentrations in bile and cystic fluid thorough physical
Scribd. (n.d.). Complete albendazole
may be increased about 2-fold; however, plasma assessment to
information from drugs. Scribd. Retrieved
 November 3, 2021, from levels are unchanged 4 h after dosing.  Genitourinary establish baseline
https://www.scribd.com/document/991036 Dexamethasone Albendazole C trough at steady data before drug
FREQUENCY: 18/Complete-Albendazole-Information- state was about 56% higher when coadministered Acute kidney failure, dark therapy begins, to
From-Drugs. with dexamethasone 8 mg. Monitor the patient urine. determine the
OD for albendazole adverse reactions. If an effectiveness of
interaction is suspected, adjust the albendazole therapy, and to
dose as needed evaluate for the
  Liver
occurrence of any
Abnormal Liver Function adverse effects
Tests, inflammation of liver associated with drug
DRUG TO FOOD INTERACTION: therapy.
Grapefruit juice c. Restrict amount of
 Blood drug available to
Albendazole plasma concentrations may be
patient.
elevated and the half-life may be shortened,
Decrease in the number of
increasing the risk of adverse reactions. Patients d. Periodically assess
white blood cells,
should avoid grapefruit products while taking dose.
thrombocytes, hemoglobin.
albendazole.

 Miscellaneous EDx:
Praziquantel
Fever. a. Provided patient
Albendazole sulfoxide C max may be elevated teaching regarding
about 50%, increasing the risk of adverse drug, dosage, adverse
reactions. Monitor the patient for albendazole effects, signs and
adverse reactions. If an interaction is suspected, symptoms of
adjust the albendazole dose as needed. problems to report,
and safety
precautions.
Theophylline
b. Cautioned pt. that
Although theophylline pharmacokinetics are drowsiness or
unchanged by albendazole, monitor theophylline dizziness may occur.
plasma concentrations during and after
albendazole treatment. Adjust the theophylline c. Educated client on
dose as needed. drug therapy to
promote compliance.

d. Insured the patient

takes the medication
as prescribed.

DURING:

Dx:

a. Monitored for
adverse effects (e.g.
dizziness, headache,
seizures)

b. Assessed the patient’s

status.

c. Checked if it is the
right medication.

d. If signs of toxicity
occur, stop drug at
once and notify
prescriber.

Tx:

a. Provided support and

reassurance to deal
with drug effects

b. Assisted pt. in taking

 the medication.

EDx:

a. Instructed patient to
verbalize feelings and
concerns.

b. Report nausea,
dizziness, abdominal
pain or persistent
headache to
physician.

c. Inform of drugs and

foods that can interact

d. Instruct patient to
verbalize feelings and
concerns.

AFTER:

Dx:

a. Assess
knowledge/teach
patient appropriate
use ,interventions to
reduce side effects,
and adverse
symptoms to report

b. Monitor for
effectiveness as
 exhibited by a
decrease in symptoms

c. Monitor for side

effects.

Tx:

a. Note for the

occurrence of
Reversible hair loss,
infection,
hypersensitivity
including rash and
hives, allergic
reactions.

b. Provide safety
measures (e.g.
adequate lighting,
raised side rails, etc.)
to prevent injuries.

c. Provide comfort
measures (e.g.
voiding before
dosing, taking food
with drug, etc.) to
help patient tolerate
drug effects.

EDx:

a. Monitor patient
compliance to drug
therapy.
 b. Instruct patient to
verbalize feelings and
concerns.

As a future nurses, would you recommend these drugs to your patient? Enumerate the pros and cons

Albendazole is an anthelmintic or anti-worm medication. It prevents newly hatched insect larvae/worms from growing or multiplying in the body. It is used to treat certain infections caused by
worms such as pork tapeworm and dog tapeworm. And as future nurses, we would recommend the drug to our patients who are suffering from giardiasis, trichuriasis, filariasis, neurocysticercosis,
hydatid disease, pinworm disease, and ascariasis, and other diseases. Along with its needed effects, the drug has its cons which are its adverse effects such as reversible hair loss, acute kidney
failure, headache, seizures and more mentioned above.