OLFU – College of Pharmacy

PDDS Laboratory
Name: Date: 09/20/2021
CE no. 1 Marie Anthoinette Aquino
Powders Year and Sec.
2-YA-3
Group no.

A. Computation
Compounding of (Rx1) Computed Therapeutic Use
Computed amounts for 14 charts amount
Thyroxine 0.252mg Hypothyroidism can be treated
using the thyroid hormone
levothyroxine known as
Thyroxin. The thyroid gland
naturally produces thyroid
hormones, which are replaced or
boosted by this supplement. Low
thyroid hormone levels can occur
on their own or due to thyroid
gland radiation, medication, or
surgery. Mental and physical
activity requires thyroid
hormone to be present.
Lactose 210mg Lactose is commonly used as a
filler and binder in
pharmacologically solid oral
prescription formulations.
Lactose is profitable because it is
entirely affordable, has a
balanced flavor, and has low
hydrophilicity. It also has the
potential to become agreeable
to chemical agents and a variety
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PDDS Laboratory
of excipients.
Weight of each chart 0.018mg &
15mg
Total weight of 14 charts 210.252mg

Compounding of (Rx2)
Computed amounts for 16 charts
Salicylic acid 2.8mg Salicylic acid, a keratolytic (skin-
peeling agent), causes the skins
outer layer to a slough; it treats
acne, dandruff, seborrhea, or
psoriasis as well as the removal
of corns, calluses, and warts
using salicylic acid topical for the
skin.
Lactose 9596.80mg Lactose is commonly used as a
filler and binder in
pharmacologically solid oral
prescription formulations.
Lactose is profitable because it is
entirely affordable, has a
balanced flavor, and has low
hydrophilicity. It also has the
potential to become agreeable
to chemical agents and a variety
of excipients.

Compounding of Rx3
Computed amounts for 120 g
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PDDS Laboratory
Calamine 18g Calamine is used to cure mild
skin irritations such as poison
ivy, poison oak, and poison
sumac by relieving pain, itching,
and discomfort. It can also dry
up the oozing and weeping
caused by irritation from these
plants with this remedy.
Magnesium Stearate 1.2g Magnesium stearate is a filler
that commonly found in
pharmaceutical capsules. It's
called a "flow agent" because it
keeps the different contents in
capsules from clinging to each
other and the capsule-making
equipment. It aids in improving
pharmaceutical capsule
consistency and quality control.
Talc 70g Talc is used to prevent the
buildup of fluid in the chest
caused by malignant pleural
effusion. It works by irritating
the lining of the chest cavity,
causing it to tighten up and
move no space for fluid. Talc
contains sclerosing agents, which
are a type of drug that contains
talc.
 OLFU – College of Pharmacy
PDDS Laboratory
B. Prepare the label for Rx1

C. Supply the following information for Rx1

Use(s):
Thyroxine is use for cretinism, non-toxic goiter, myxoedema coma, adult hypothyroidism, and
empirical use.

Label:
Prescribe by the physicians.

Container:
Polypropylene container with tamper-evident low density polyethylene lid
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PDDS Laboratory
Description:
Levothyroxine is a powdered substance that absorbs moisture from the air and is odorless and
lighter in color (particularly yellow powdered substance to buff-colored). It has no flavor and
mildly dissolves in water or ethanol. This is available as an injection or as powdered corn syrup
or molasses.

Beyond Use Date:

Levothyroxine sodium pills are extremely stable, losing less than 5% of their declared potency in
24 months, compared to 10% in 9 months for other products.

Remarks:
The thyroid gland is an integral part of the endocrine system since it secretes numerous
hormones that impact everything from heart health to metabolism. Thyroxine, usually referred
to as T4, is one of these hormones. Thyroxine is one of the most significant thyroid hormones
since it affects so many different body systems. It is critical to general health that you
understand thyroxine.

Thyroxine is a thyroid hormone released into the bloodstream by the thyroid gland. Thyroxine
enters the bloodstream and goes to several organs, including the liver and kidneys, transformed
to triiodothyronine, the active hormone. Thyroxine is critical for heart and digestive health,
metabolism, brain growth, bone health, and muscular control. Proper thyroxine levels are vital
to good health since they impact nearly every system in the body. This is why many doctors will
check for thyroid issues by checking T4 levels and the more normal T3 levels.

Reference/s:
Medicine plus. (2012, February 11). Talc Intrapleural. Retrieved from
https://medlineplus.gov/druginfo/meds/a608011.html
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PDDS Laboratory
Rxlist. (n.d.). CALAMINE-ZINC-OXIDE-TOPICAL. Retrieved from
https://www.rxlist.com/fdb/drugs/18702/calamine-zinc-oxide-topical-brand.htm
Wilson, R.D. (2019, November 22). Everything You Should Know About Magnesium Stearate.
Retrieved from https://www.healthline.com/health/magnesium-stearate
Drug development. (n.d.). Lactose in Pharmaceutical Applications. Retrieved from https://drug-
dev.com/lactose-in-pharmaceutical-applications/
Multum, C. (n.d.). Salicylic acid topical. Retrieved from https://www.drugs.com/mtm/salicylic-
acid-topical.html
Webmd. (n.d.). L-Thyroxine Tablet. Retrieved from https://www.webmd.com/drugs/2/drug-
13826/l-thyroxine-oral/details
Prasad, P. (2015, October 19). Thyroid and antithyroid drugs. Retrieved from
https://www.slideshare.net/docpravin/thyroid-and-antithyroid-drugs-53721275
emc. (2021, August 11). Levothyroxine 50mcg tablets. Retrieved from
https://www.medicines.org.uk/emc/product/5683/smpc#gref
Your hormones. (n.d.). Alternative names for thyroxine. Retrieved from
https://www.yourhormones.info/hormones/thyroxine/