NAME: Avelino, Debbie Chenn S.

BS PHARMACY 1B

ACTIVITY 5
CHAPTER 5

PLEASE HIGHLIGHT IN YELLOW OR BOX IN YOUR FINAL ANSWER.

PLEASE SHOW YOUR SOLUTIONS WHEN NEEDED (handwritten). PLEASE WRITE LEGIBLY
AND SCAN CLEARLY.

1. A pharmacist incorporates 6 g of coal tar into 120 g of a 5% coal tar ointment. Calculate the %w/w of
coal tar in the finished product.

9.52% w/w coal tar

2. A 12 mL of peppermint oil were dissolved in 68 mL of alcohol to make a solution, what would be the
concentration of peppermint oil in the solution?

15%

3. A formula for an antifungal shampoo contains 2% w/v ketoconazole. How many grams of ketoconazole
would be needed to prepare 25 liters of shampoo?

500g
 4. If 500 g of dextrose are dissolved in 600 mL of water with a resultant final volume of 1 L, what is the
percentage strength of dextrose in the solution on a w/w basis?

45.45%

5. DESONATE gel contains 0.05% w/w desonide.

Calculate (a) the quantity of this agent, in grams, in each 60-g tube of product

(b) and the concentration of desonide, in mg/g of gel.

a) 0.03g
b) 0.5mg/g

6. A topical gel contains 1.2% w/w clindamycin phosphate and 0.025% w/w tretinoin. Calculate the quantity
of each of these ingredients on an mg/g basis.

0.25mg/g
 7. Each gram of an ointment contains 2.5 mg of miconazole nitrate. The ointment is available in 50-g tubes.

Calculate (a) the percent concentration of miconazole nitrate in the ointment

(b) and the quantity of miconazole nitrate, in grams, in each tube of ointment.

a) 0.25%
b) 0.125g

8. The formula for 1 L of an elixir contains 0.25 mL of a flavoring oil. What is the percent strength (v/v) of the
flavoring oil in the elixir?

0.025%

9. What is the percent strength (v/v) if 225 g of a liquid having a specific gravity of 0.8 are added to enough
water to make 1.5 L of the solution?

25%

10. In the preparation of an intravenous infusion, a vial containing 115 mg of drug is diluted to 5 mL with
sodium chloride for injection. Then, the contents of the vial are added to 110 mL of an infusion solution.

Calculate the drug strength of the final infusion in:

(a) mg/mL, (b) percent strength, and (c) ratio strength.

a) 1mg/ml

b) 0.1%w/v

c) 1:1000