We are Ultrasound Professionals

ALPINION MEDICAL SYSTEMS

All information in the presentation are highly confidential and no part of contents may be informed or transmitted without pe rmission from ALPINION Medical Systems.
We are Ultrasound Professionals

Part 01. Corporate Overview

Part 02. Technology Highlights

Part 03. Products

2/29
CORPORATE OVERVIEW
General Information

Establishment 1968

Headquarters Seoul, Korea.

Sales 2.3G (2017)

Overseas USA, Europe, China, Japan, etc.

Employee 3,600

4/29
General Information

We are Ultrasound Professionals

Since we began our ultrasound business in 2007, we have focused on developing core technologies and delivering
the best value to our customers. As a value innovator in the medical industry, ALPINION progressively expands our
business scope vertically and horizontally in every ultrasound area.

Company Identity CEO

Alpinion Medical Systems Youngchun Choi

Establishment Employee
April 24, 2007 230 (as of December 2017)

Major Shareholder Sales

ILJIN Holdings (Acquired in 2008) 47M USD (2017)

Headquarters Overseas
77, Heungan-daero 81beon-gil, ALPINION USA
Dongan-gu, Anyang-si, Gyeonggi-do, ALPINION MEDICAL Deutschland GmbH
Korea ALPINION GuangZhou Medical Systems

Website
www.alpinion.com

5/29
Philosophy

Mission To achieve value innovation to contribute to the healthier life of people

Vision2020 To become Korea's leading medical device company which realizes strong and sustainable growth

Innovation
Embrace change and enhance competitiveness

Customer Respect
Deliver the highest quality of healthcare
product and service

Harmony
Pursue growth in unison

Integrity
Talent Development Build open and honest relationships with
Develop new generations of professionals communication
to carry on our commitment to excellence
6/29
Milestone

Lay the cornerstone
• Established VIMED (2007)
• Acquired by ILJIN Group (2008)
• Launched the 1st E-CUBE system,
E-CUBE 9 (2011)
Strengthen the basis
• Expanded the E-CUBE line up
• Launched the HIFU system,
Alpius 900 (2015)
Jump to leading
Sustained growth
position
• Launching new products • Leading medical device
• Reinforcing products’ company with strong and
competitiveness continuous growth
• Pursuing new medical device
business development

Phase 1. Phase 2. Phase 3. Phase 4.

2007 - 2011 2012 - 2018 2019 - 2020 2021 -

7/29
Business Portfolio

Transducers

Diagnostic
Ultrasound

Therapeutic
Ultrasound

8/29
Global Sales Channel

ALPINION
Germany

ALPINION
ALPINION HQ USA
ALPINION
China

9/29
TECHNOLOGY HIGHLIGHTS
Technology Highlights

Acoustic Technology Diagnostic Technology

(Transducer) (System)

11/29
1. Acoustic Technology
∙ In-housed R&D, manufacturing, and total inspection

Fast Low Best Easy Expansion Fast & Accurate

Repair Maintenance Cost Compatibility to New Applications Full Automatic Inspection

12/29
1. Acoustic Technology

Crystal Signature™ PowerView™

-60 Conventional structure

Ultrasonic Matching Gear
-65

-70

Magnitude (dB)
-75

-80

-85

-90

-95

-100
1 2 3 4 5
Frequency (MHz)
[General PZT Image] [Crystal SignatureTM Image] [Cool Liner] [Ultrasonic Matching Gear]

13/29
1. Acoustic Technology

ExFast 3D/4D™ SensitiView™ Technology

[Previous 3D/4D Acquisition] [ExFast 3D/4DTM] [SensitiViewTM Technology Structure]

ExFast 3D/4DTM is a transducer technology which acquires volume The high-performance low loss cable transfers high-sensitive signals for
data as quickly as 24Hz in general fetal 3D/4D scans. optimum impedance matching with the system. The results are
significantly enhanced sensitivity and high-resolution images.

14/29
1. Acoustic Technology
∙ Featured Transducers

SVC1-6H SC1-4HS IO3-12 L3-12HWD

The world-first single crystal The largest aperture single The world-first intra-oral
volume convex transducer crystal convex transducer transducer

15/29
2. Diagnostic Technology
∙ System Design

System Hardware Software Display

FleXcan™ Pro Optimal Imaging

Architecture SuiteTM Plus
• PIHI (Phase Inversion Harmonic Imaging)
• FTHI (Filtered Tissue Harmonic Imaging)
Wide Full HD LED Monitor with
Connectivity • SCI,(Spatial Compounding Imaging) IPS technology
• FCI (Frequency Compounding Imaging)
• DICOM 3.0 standard
• SRI (Speckle Reduction Imaging) / FullSRI™
• MPPS (Modality Performed Procedure Step)
• Modality work list
• Xpeed™ High Resolution Touchscreen

Excellent Storage Capability Application-Dedicated Software

• USB • CUBE StrainTM,
• CD/DVD • Stress Echo
• Network storage connections • Elastography
• Needle VisionTM, Plus
• Volume AdvanceTM / Volume MasterTM
• Live HQTM
• Auto IMT
• Full Cardiac Measurement &report

16/29
2. Diagnostic Technology

FleXcan™ Pro Architecture Optimal Imaging Suite™ Plus

[Conventional]

[E-CUBE Series]

[Spatial Compounding] [Synthetic Aperture Technology]

ALPINION’s unique imaging platform, FleXcanTM Pro, is a software ALPINION’s integrated post-processing technology, Optimal Imaging
driven architecture applied with the raw data imaging processing SuiteTM Plus, provides clearer images in the borderline of organs by
technology thus to ensure excellent imaging performance and reducing artifacts and signal noises, and quickly optimizes the images for
efficient clinical exams. each application.

17/29
2. Diagnostic Technology
∙ Miniaturized Ultrasound System

Firmware OS

Digital H/W

Analog H/W

Acoustic Module

18/29
PRODUCTS
System Line-up
Performance

Price

20/29
Transducer Portfolio

Convex

SC1-4H SC1-4HS SC1-6H SC1-6 C1-6 C1-6CT C5-8N

Linear

L3-8 L3-8H L3-12X L3-12H L3-12H Wide L8-17X L8-17H

Phased Array

SP1-5X MP1-5X SP1-5 P1-5CT SP3-8

Endocavity

EV3-10X EC3-10X EV3-10H EC3-10H EV3-10 EC3-10

Volume

SVC1-6H SVC1-6 VC1-6 VE3-10H

Special

CW 2.0/5.0 TEE3-7 IO3-12 IO8-17

Frequency
21/29
Quality in your daily practice

Product Information

Applications General Imaging, OB/GYN, Cardiology, Orthopedics, etc

Design

21.5” Monitor & Motorized Lift Enhanced

10.4” Touchscreen Control Panel Computing Power

FullSRITM Auto NT Auto IMT

Features Needle VisionTM Plus Live HQTM Stress Echo
Elastography Volume AdvanceTM CUBE StrainTM

Clinical
Images

[Elastography] [Liver in Dual Live mode] [Volume AdvanceTM]

22/29
Bringing excellence in daily care

Product Information

Applications General Imaging, OB/GYN, Cardiology, Orthopedics, etc

Design

21.5” Monitor & GPU with Full Color Backlit

10.4” Touchscreen 120GB SSD + 1TB HDD LED Control Panel

FullSRITM Auto NT Auto IMT

Features Needle VisionTM Plus Live HQTM Stress Echo
Elastography Volume MasterTM CUBE StrainTM

Clinical
Images

[Fetal brain MSV] [Renal Vessel] [Cardiac in CW]

23/29
Touch your daily practice

Product Information

Applications General Imaging, OB/GYN, Cardiology, Orthopedics, etc

Design

21.5” Monitor & 512GB SSD Full Color Backlit

10.4” Touchscreen LED Control Panel

FullSRITM Auto NT Auto IMT

Features Needle VisionTM Plus Live HQTM Stress Echo
Elastography Volume MasterTM CUBE StrainTM

Clinical
Images

[Live HQTM] [Renal Perfusion in DPDI] [Mitral regurgitation jet]

24/29
Smartness for your daily practice

Product Information

Applications General Imaging, OB/GYN, Cardiology, Orthopedics, etc

Design

21.5” Monitor & 512GB SSD

10.4” Touchscreen

FullSRITM Auto NT Auto IMT Battery (20~25min)

Features Needle VisionTM Plus Live HQTM Stress Echo USB 3.0
Elastography Volume AdvanceTM CUBE StrainTM Wireless LAN

Clinical
Images

[3D/4D] [Excellent Image in MSK] [Abdominal Image] [Interventricular septum in TDI]

25/29
 Continuous Innovation All-in-one Solution for Top Born Powerful and Compact
- Superior and Reliable Performers

[Carotid Artery Live Dual] [Renal PW Spectrum] [Live HQTM] [Stress Echo] [Kidney in Dual mode] [22-week fetal brain]

26/29
Innovation Meets Portability, Indeed.

Product Information

Applications Anesthesiology, Emergency medicine, Musculoskeletal, Sport medicine, General imaging, etc

Design

[Sliding Keyboard Cover]

FullSRITM Anatomical M-mode TDI

Features Needle VisionTM Plus XpeedTM Auto IMT
Panoramic Imaging CW

Clinical
Images

[Color Doppler] [Supraspinatus Tendon] [Renal Perfusion

in Power Doppler]

27/29
PRODUCTS
The safer and smarter choice
For the treatment of uterine fibroids : Ultrasound-Guided HIFU (High Intensity Focused Ultrasound)

Product Information

• Water circulation module • Easy and convenient control panel

Safe • Cavitation detection
Quick • EZ Workflow TM
• Beam Steering

• 3D modelingTM
Accurate • Target ForecasterTM Compact • Portable
• Clear ViewTM

Clinical
Images

[Before] [After] [3 Month After]

29/29
Thank you