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Pathoanatomy Slides 3rd Year
Pathoanatomy Slides 3rd Year
Fibroadenoma (50) is the most common benign breast tumor, mostly in young women. It consists in two
components (epithelial and fibroblastic), estrogen-dependent, slowly growing.
Adenocarcinoma is a malignant
epithelial tumor, originating from
glandular epithelium of the
colorectal mucosa. It invades the
wall, infiltrating the muscularis
mucosae, the submucosa (photo)
and thence the muscularis propria.
(Notice the end-point of muscularis
mucosae. At left from this point,
muscularis mucosae is continuous.
At right from this point, muscularis
mucosae is destroyed by tumor
cells invasion.) Tumor cells
describe irregular tubular
structures, harboring stratification, multiple lumens, reduced stroma ("back to back" aspect). Depending
on glandular architecture, cellular pleomorphism and mucosecretion of the predominant pattern,
adenocarcinoma may present 3 degrees of differentiation: well, moderate and poorly differentiate.
On microscopic examination, there are intersecting bundles of spindle cells producing collagen.
Lipoma (63)
Adenolipomas, Angiolipoleiomyomas,
angiolipomas, chondroid lipomas, Hebernomas,
Intradermal spindle cell lipomas, spindle cell
lipomas, pleomorphic lipomas
Chondroma (64)
Osteosarcoma (68)
Leiomyosarcoma (62a)
Neurinoma (74)
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Meningioma (75)