Members:

Hannah P. Aguid
Alessandra S. Mercado
Ivy Rose L. Morante

DRUG STUDY
NAME MECHANISM INDICATION/ SIDE EFFECT NURSING
OF ACTION CONTRAINDICATI RESPONSIBILITY
ON

GENERIC Paracetamol may INDICATION: BODY AS A ● Assess patient’s

NAME: cause analgesia by -To relieve mild to WHOLE: fever
-Paracetamol inhibiting CNS moderate pain due to -hemolytic or pain: type of
prostaglandin things such as anemia, pain, location,
synthesis. The headache, leukopenia, intensity,
BRAND NAME: mechanism of muscle and joint pain, neutropenia, duration,
-Biogesic morphine is backache and period pancytopenia, temperature,
believed pain. It is also used to thrombocytopenia and diaphoresis.
to involve bring down a high
CLASSIFICATIO decreased temperature. For this GI: ● Assess allergic
N: permeability of the reason, paracetamol -Nausea, reactions: rash,
-Analgesic (Non- cell membrane to can Diarrhea, urticaria; if these
opioid), Antipyretic sodium, which be given to children Constipation, occur, drugs may
results after Abdominal pain, have to be
in diminished vaccinations to dry mouth. discontinued.
FREQUENCY: transmission of prevent
-q4 pain post-immunization SKIN: ● Teach patient to
impulses therefore pyrexia -rash,urticaria. recognize signs
analgesia. (high temperature). of
DOSAGE: Paracetamol is often UROGENITAL: chronic
-500mg 1 tab included in cough, -The insertion of overdose:
cold urinary catheters bleeding,
and flu remedies. during urinary bruising,
ROUTE: surgical malaise, fever,
-Oral interventions may sore
CONTRAINDICATI lead to Throat.
ON: catheter-related
- Hypersensitivity to bladder ● Tell patient to
acetaminophen or discomfort notify prescriber
phenacetin; use with (CRBD) in the for
alcohol. postoperative pain/fever
 period. lasting for more
than 3
days.

GENERIC Amoxil is a INDICATION: BODY AS A ● Watch for

NAME: prescription WHOLE: seizures; notify
Amoxicillin medicine used to To reduce the skin rash; itching; physicians
treat the symptoms development of shortness of immediately if a
of many different drug-resistant bacteria breath; trouble patient develops
BRAND NAME: types of bacterial and maintain the with breathing; or increases
Penicillins, Amino infections such as effectiveness of trouble with seizure activity.
Tonsillitis, AMOXIL swallowing; or
CLASSIFICATIO Bronchitis, (amoxicillin) and any swelling of
N: Pneumonia, and other antibacterial your hands, face,
● Monitor signs of
Penicillins, Amino infections of the drugs, AMOXIL mouth, or throat
pseudomembran
ear, nose, throat, should be used only to after you or your
ous colitis,
skin, or urinary treat infections that child receive this
including
FREQUENCY: tract. Amoxil may are proven or strongly medicine.
diarrhea,
It is usually taken be used alone or suspected to be caused Amoxicillin may
abdominal pain,
every 12 hours with other by bacteria. When cause diarrhea,
fever, pus or
(twice a day) or medication culture and and in some
mucus in stool,
every 8 hours (three susceptibility cases, it can be
and other severe
times a day) with or information are severe.
or prolonged GI
without food. available, they should
problems
be considered in
(nausea,
selecting or modifying GI:
vomiting,
DOSAGE: antibacterial therapy. -
heartburn).
The usual dose of In the absence of such PSEUDOMEMB
Notify
amoxicillin is data, local RANOUS
physicians or
250mg to 500mg epidemiology and COLITIS,
nursing staff
taken 3 times a day. susceptibility patterns diarrhea, nausea,
immediately of
may contribute to the vomiting,
these signs.
empiric selection of elevated liver
ROUTE: therapy. enzymes.
Amoxicillin comes
as a capsule, a ● Monitor signs of
tablet, a chewable CONTRAINDICAT SKIN: allergic reactions
tablet, and as a ED: - rashes, urticaria. and anaphylaxis,
suspension (liquid) Amoxicillin is including
to take by mouth. contraindicated in pulmonary
patients with a known UROGENITAL: symptoms
serious - cause crystals to (tightness in the
hypersensitivity form in the urine. throat and chest,
reaction (i.e., wheezing, cough
 anaphylaxis) to other -blood dyscrasias. dyspnea) or skin
beta-lactams. Patients reactions (rash,
with allergies or atopic pruritus,
conditions including urticaria). Notify
asthma, eczema, hives physician or
(urticaria), or hay nursing staff
fever may have a immediately if
greater risk for these reactions
hypersensitivity occur.
reactions to
penicillins.

GENERIC Salbutamol is used INDICATION: CNS: ● Check and

NAME: to produce For the relief of Restlessness, verify with the
Salbutamol bronchodilation or bronchospasm in all apprehension, doctor's order
relieve nasal types of bronchial anxiety, fear, CNS and
congestion. It asthma, chronic stimulation, ● Observe rights
BRAND NAME: relieves reversible bronchitis, and vertigo, headache, in medication
Alfreton bronchospasm by emphysema. This also weakness, administration
relaxing the relieves productive tremors, such as giving
smooth muscles of and wheezing coughs drowsiness, the right drug to
CLASSIFICATIO the bronchioles in associated with insomnia, the right patient
N: conditions bronchitis, hyperactivity, using the right
Bronchodilator associated with pneumonia, and other malaise route and at the
asthma, bronchitis, respiratory infections. right time.
emphysema, or CV: Cardiac ● Monitor ECG,
FREQUENCY: bronchiectasis. arrhythmias, serum
To be taken 3-4 Bronchodilation palpitations, electrolytes, and
times a day or as may additionally CONTRAINDICAT tachycardia, chest thyroid function
prescribed by the facilitate ED: pain, test results.
physician expectoration. Contraindicated in hypertension ● Administer
patients with a history accurately
of hypersensitivity to EENT: dry and because adverse
DOSAGE: any of its components. irritated nose and reactions and
Adults and children throat with tolerance might
over 12 years old: inhaled form, occur.
2-4 teaspoons nasal congestion, ● Raise side rails
(10-20 mL). epistaxis, up because the
7-12 years old: 2 hoarseness client might be
teaspoons (10 mL). restless and
2-6 years old: 1-2 Dermatologic: drowsy because
teaspoons (5-10 Sweating, pallor, of this drug.
mL). flushing ● Keep the room
well-lit and see
 GI: Nausea, to it that the
ROUTE: vomiting, client has a
To be taken orally heartburn, person with him
or per orem unusual or bad closely in case
taste in the mouth of vertigo.
● Assess lung
Metabolic: sounds, PR, and
hypokalemia BP before drug
administration
Musculoskeletal: and during the
muscle cramps peak of
medication.
Respiratory: ● Assess pulse for
Respiratory rhythm.
difficulties, ● Auscultate lungs
pulmonary for the presence
edema, coughing, of adventitious
bronchospasm, breath sounds
paradoxical that may signal
airway resistance pulmonary
with repeated, edema, airway
excessive use of resistance or
inhalation bronchospasm.
preparations, ● Inspect the
increased sputum client’s nail bed
production, and oral mucosa
dyspnea for pallor.
bronchitis ● Place the client
in a position of
comfort to
facilitate
optimum rest
and sleep.

GENERIC INDICATION: Dizziness, ● Watch for

Metronidazole
NAME: To treat systemic headache, seizures; notify
diffuses into the
METRONIDAZOL anaerobic infections diarrhea, nausea the physician
organism, inhibits
E caused by Bacteroides or vomiting, immediately if a
protein synthesis
fragilis, Clostridium stomach pain or patient develops
by interacting with
Difficile, Clostridium cramps, loss of or increases
DNA, and causes a
BRAND NAME: perfringens, appetite, dry seizure activity.
loss of helical
Triconex, Flagyl, Eubacterium, mouth, metallic ● Monitor signs of
DNA structure and
Flagyl ER, Flagyl Fusobacterium, taste in the mouth peripheral
strand breakage.
IV RTU Peptococcus, neuropathy
 Therefore, it causes Peptostreptococcus, CNS: Ataxia, (numbness,
cell death in and Veillonella sp dizziness, tingling). ...
CLASSIFICATIO susceptible encephalopathy, ● Monitor signs of
N: Antiprotozoal organisms. fever, headache, disulfiram-like
Amoebicide light-headedness, reaction (i.e.,
The mechanism of
Antibiotics, Other peripheral toxicity
action of
neuropathy, occurring when
metronidazole
seizures (high this drug is taken
occurs through a
doses) with alcohol).
four-step process.
FREQUENCY: CONTRAINDICAT ●
Step one is the
Adults—500 or 750 ED: EENT: Dry
entry into the
milligrams (mg) 3 It should not be mouth,
organism by
times a day for 5 to administered to lacrimation
diffusion across the
10 days. patients with active (topical form),
cell membranes of
Children—Dose is neurological disorders metallic taste,
anaerobic and
based on body or a history of blood pharyngitis
aerobic pathogens.
weight and must be dyscrasias,
However,
determined by your hypothyroidism, and GI: Abdominal
antimicrobial
doctor. The dose is hypoadrenalism. cramps or pain,
effects are limited
usually 35 to 50 anorexia,
to anaerobes. Step
milligrams (mg) per diarrhea, nausea,
two involves
kilogram (kg) of pancreatitis,
reductive
body weight per vomiting
activation by
day, divided into 3
intracellular
doses, for 10 days. HEME:
transport proteins
Leukopenia
by altering the
chemical structure
DOSAGE: MS: Back pain
of
Adult and Pediatric
pyruvate-ferredoxi
Dosage Forms and SKIN: Burning
n oxidoreductase.
Strengths sensation,
The reduction of
stinging
metronidazole
Capsule sensation, dry
creates a
375mg skin(topical
concentration
form); erythema,
gradient in the cell
Tablet pruritus, rash,
that drives uptake
250 mg urticaria(oral and
of more drugs and
500 mg parenteral forms)
promotes free
radical formation
Tablet, OTHER:
that is cytotoxic.
extended-release injection site
Step three,
750 mg edema, pain, or,
interactions with
tenderness
intracellular
Infusion solution targets, is achieved
500 mg/100mL by cytotoxic
particles
interacting with
host cell DNA
ROUTE: resulting in DNA
Metronidazole strand breakage
500mg/100ml and fatal
Intravenous destabilization of
Infusion should be the DNA helix.
infused Step four is the
intravenously at an breakdown of
approximate rate of cytotoxic products.
5 ml/minute (or one Metronidazole is
bag infused over 20 also cytotoxic to
to 60 minutes). Oral attentively
medication should anaerobic bacteria
be substituted as like Helicobacter
soon as feasible. pylori and
Gardnerella
vaginalis, but the
mechanism of
action to these
pathogens is not
well understood.

GENERIC Inhibits INDICATION: BODY AS A ● Assess

NAME: prostaglandin Mild-to-moderate pain WHOLE: peripheral
Ibuprofen synthesis. or dysmenorrhea. headache, edema using
Therapeutic Inflammatory dizziness, girth
Effects: Decreased disorders, including drowsiness, measurements,
BRAND NAME: pain and Rheumatoid arthritis psychic volume
Advil inflammation. (including juvenile), disturbances. displacement,
Reduction of fever Osteoarthritis. and
Lowering of fever. measurement of
CLASSIFICATIO Unlabeled Use: Slows GI: pitting edema
N:therapeutic: progression of lung BLEEDING, (See Appendix
antipyretics, disease in cystic HEPATITIS, N). Report
antirheumatics, fibrosis patients >5 yrs constipation, increased
nonopioid of age (high doses). dyspepsia, swelling in feet
analgesics, nausea, vomiting, and ankles or a
nonsteroidal abdominal sudden increase
anti-inflammatory CONTRAINDICAT discomfort. in body weight
agentsPharmacologi ED: due to fluid
c: nonopioid Hypersensitivity to the retention.
analgesics drug. Active peptic SKIN: ● Assess pain and
ulcer; EXFOLIATIVE other variables
hypersensitivity.Neona DERMATITIS, (range of
tes with congenital STEVENS-JOHN motion, muscle
heart disease, SON strength) to
FREQUENCY: suspected necrotizing SYNDROME, document
Adults and enterocolitis, and TOXIC whether this
teenagers—400 active bleeding EPIDERMALNE drug is
milligrams (mg) (parenteral). CROLYSIS, successful in
every four to six rashes. helping manage
hours, as needed. the patient's pain
Children over 6 UROGENITAL: and decreasing
months of cystitis, impairments.
age—Dose is based hematuria, renal ● Assess blood
on body weight and failure. pressure (BP)
must be determined periodically and
by your doctor. The compare to
dose usually is 10 normal values
milligrams (mg) per (See Appendix
kilogram (kg) of F). NSAIDs can
body weight every increase BP in
six to eight hours, as certain patients.
needed, up to 40 mg
per kg per day

DOSAGE:
200 mg

ROUTE:
Ibuprofen, a
nonsteroidal
anti-inflammatory
drug (NSAID), is
available in 400 mg,
600 mg, and 800 mg
tablets for oral
administration.
REFERENCES:

-DRUG STUDY.pdf - DRUG GENERIC NAME Paracetamol BRAND NAME Biogesic DOSE
500mg 1 tab ROUTE Oral FREQUENCY q4 CLASSIFICATION Analgesic(Nonopioid
-Amoxicillin | Davis's Drug Guide for Rehabilitation Professionals | FA Davis PT Collection |
McGraw -Hill Medical
Metronidazole - StatPearls
-Acetaminophen - drug study - Nursing - SOC SCI 101 - UNP
-Oxytocin - drug study - Bachelor of Science in Nursing - 101
-Drug Study Ibuprofen - Name Classification Mechanism ofAction Indication Contraindication
Adverse