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In-vitro catalytic, antimicrobial and antioxidant activities of bioengineered

copper quantum dots using Mangifera indica (L.) leaf extract

Article  in  Materials Chemistry and Physics · January 2020

DOI: 10.1016/j.matchemphys.2019.122052

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 Materials Chemistry and Physics 239 (2020) 122052

Contents lists available at ScienceDirect

Materials Chemistry and Physics

journal homepage: www.elsevier.com/locate/matchemphys

In-vitro catalytic, antimicrobial and antioxidant activities of bioengineered

copper quantum dots using Mangifera indica (L.) leaf extract
Humaira Rani a, Satarudra Prakash Singh a, Thakur Prasad Yadav b, Mohd Sajid Khan c,
Mohammad Israil Ansari d, Akhilesh Kumar Singh a, *
a
Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Lucknow, 226028, India
b
Department of Physics, Institute of Science, Banaras Hindu University, Varanasi, 221005, India
c
Nanomedicine and Nanotechnology Lab., Department of Biosciences, Integral University, Lucknow, 226026, India
d
Department of Botany, University of Lucknow, Lucknow, 226007, India

H I G H L I G H T S G R A P H I C A L A B S T R A C T

� Mangifera indica is used to synthesize

and stabilize copper quantum dots (Cu
QDs).
� Cu QDs disintegrate hazardous methy­
lene blue in 195 min.
� Cu QDs depict good antibacterial activ­
ity against E. coli and S. aureus at 24 h.
� Cu QDs exhibit optimal antioxidant ac­
tivity against 1,1-diphenyl-2-picrylhy­
drazyl within 30 min.

A R T I C L E I N F O A B S T R A C T

Keywords: A simple green chemistry route has been developed for the synthesis of copper (Cu) quantum dots (QDs) from
Antibacterial activity copper sulfate using leaf extract of Mangifera indica (L.) with assessment of their catalytic, antibacterial and
Antioxidant property antioxidant activities. The impact of quantities of leaf extract, concentrations of copper sulfate, incubation
Catalytic activity
temperature, pH and reaction time were investigated so as to attain regulation on the QDs particle size and
Copper quantum dots
Nanoparticles
stability. The bio-fabrication of Cu QDs was studied by employing UV–Visible (UV–Vis) spectrophotometry at
Methylene blue wavelength (λmax) 338 nm. Fourier-Transform Infrared spectroscopy (FTIR), X-ray photoelectron spectroscopy
Organic dyes (XPS), energy dispersive X-ray spectroscopy (EDS), Scanning Electron Microscopy (SEM), Transmission Electron
Microscopy (TEM) along with Selected Area Electron Diffraction (SAED) as well as X-Ray Diffractometer (XRD)
were employed to characterize the morphology as well as structure of Cu QDs. The FTIR spectra depicted
polyphenolic compound ‘mangiferin’ as major phytochemical from M. indica leaf extract that functioned as
reducing, capping and stabilizing agent during Cu QDs fabrication. Highly stable spherical Cu QDs with very
narrow size distributions (4–7 nm) have been observed. These Cu QDs revealed distinctive catalytic activity
(against the reduction of anthropogenic prominent contaminant methylene blue for environment protection),
potent antimicrobial activity (against Escherichia coli KT45/45A and Staphylococcus aureus KT68) and free radical

* Corresponding author. Amity Institute of Biotechnology, Amity University Uttar Pradesh, Lucknow Campus, Uttar Pradesh, India.
E-mail addresses: aksingh2@lko.amity.edu, akhiliit@gmail.com (A.K. Singh).

https://doi.org/10.1016/j.matchemphys.2019.122052
Received 6 June 2019; Received in revised form 16 August 2019; Accepted 21 August 2019
Available online 22 August 2019
0254-0584/© 2019 Published by Elsevier B.V.

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