St.

Paul University Dumaguete

College of Nursing

DRUG STUDY
Name:____________________________________________________________________ Area:_______________________________ Date:_________________
Year/Section_________________________________________ Clinical Instructor:_________________________________________________

Name of Drug Dosage, Route, Mechanism of Indication Adverse Special Nursing

Frequency and Action Reactions Precautions Considerations
Timing
Generic: Dosage: Methergine For routine - hypertension Caution should - Assess patient
Intramuscularly: (methylergonovin management associated in be exercised in for any signs and
methylergonovin 1 mL, 0.2 mg, as e maleate) acts after delivery of several cases with the presence of symptoms of
e required directly on the the placenta; seizure sepsis, hypertension,
smooth muscle of postpartum and/or headache. - obliterative cramps, nausea,
Intravenously: the uterus and atony and hypotension has - vascular disease, vomiting,
Brand: 1 mL, 0.2 mg increases the hemorrhage; nausea and hepatic or dyspnea.
Methergine tone, rate, and subinvolution. vomiting renal
Orally amplitude of Under full Rarely observed involvement. - Monitor BP,
One tablet, 0.2 rhythmic obstetric reactions have Also use with heart rate,
mg, 3 or 4 times contractions. supervision, it included: caution during uterine response.
daily in the Thus, it induces a may be given in - acute myocardial the second stage
puerperium for a rapid and the second stage infarction of labor. The Assess calcium
maximum of 1 sustained tetanic of labor - transient necessity for levels –
week uterotonic effect following chest pains, manual removal effectiveness ↓
which shortens delivery of the -arterial spasm of a retained with
the third stage of anterior (coronary and placenta should hypocalcemia.
Route: labor and reduces shoulder. peripheral), occur only rarely
- Intramuscular blood loss. - bradycardia, with proper -Monitor uterine
-tachycardia, technique and bleeding and
- Intravenous -dyspnea, adequate notify physician
- hematuria, allowance of of any changes.
- Oral (after -thrombophlebitis, time for its
delivery of the -water intoxication, spontaneous - Instruct the
anterior shoulder, -hallucinations separation. mother not to
after delivery of - leg cramps, breastfeed within
the placenta, or - tinnitus 12 hours after
 during - nasal congestion, taking
the puerperium) - diarrhea, methylergonovin
- diaphoresis, e for it may pass
Frequency: - palpitation into breast milk
Intramuscular - foul taste in small amounts
at intervals of 2-4 - anaphylaxis, and could affect a
Classification hours. Contraindications Side Effects: nursing baby.
Functional: - High blood - Hives
Uterotonic agents Intravenous pressure - Difficulty - Teach the
- administered - Toxemia of breathing patient to do or
slowly over a pregnancy - Swelling of your use a breast
Chemical: period of no less - Hypersensitivity face, lips, tongue, pump in
Ergot Alkaloid than 60 seconds - If baby has not or throat establishing and
been delivered - stomach pain maintaining the
Oral yet. (caused by uterine milk flow until
3 or 4 times daily contractions) your
- mild headache or methylergonovin
dizziness. e treatment is
finished.
Timing:
1 week - Instruct the
patient not to eat
or drink any
grapefruit and
grapefruit juices
for it may
interact with
Methergine and
can lead to
adverse effects.

Name of Drug Dosage, Route, Mechanism of Indication Adverse Special Nursing

 Frequency and Action Reactions Precautions Considerations
Timing
Generic: Dosage: Mechanism of Cephalexin is - Gastritis and Cephalexin dose Assessment
cephalexin Oral capsule action of used in treatment abdominal pain reduction is - Watch for
-250 mg; 500 mg; cephalexin is of respiratory - Allergic reactions needed in seizures; notify
750 mg similar to tract infection, (eg. , rash, patients with physician
Brand: penicillin. It acts otitis media, skin urticaria, renal immediately if
Keflex, Panixine Oral powder for by inhibiting infections, bone angioedema, impairment. patient develops
Disperdose reconstitution bacterial cell wall infection and erythema and or increases
(125 mg/5 mL; synthesis, lack of genitourinary Steven Johnson Prolonged seizure activity.
250 mg/5 mL); bacterial cell wall infection caused syndrome) administration
results in death by sensitive - Genital and anal of cephalexin - Monitor signs or
Less severe due to lysis of organisms. pruritis may lead to symptoms of
infections bacteria. Cephalexin is - Hallucinations overgrowth of pseudomembran
Adults: 1 to 2 g normally - Arthralgia nonsusceptible ous colitis,
Children: 25 to effective in the - Joint disorder microorganisms. including
100 mg/kg eradication of - Reversible diarrhea,
streptococci from interstitial Use with caution abdominal pain,
Severe or deep- the nasopharyn nephritis in patients with fever, pus or
seated - Eosinophilia, a history of mucus in stools,
infections neutropenia, hypersensitivity and other severe
Adult: Up to 6 g thrombocytopenia, to penicillin. or prolonged GI
daily haemolytic anemia, problems. Notify
Children: Up to 4 slight elevations in physician or
g daily AST and ALT nursing staff
Classification Contraindications Side Effects: immediately of
Functional: Route: - patients with -diarrhea these signs.
Cephalosporins, - Oral known allergy to - nausea and
1st Generation the vomiting - Assess for any
cephalosporin - indigestion, signs of allergic
Frequency: group of -stomach pain reactions and
Chemical: Given in divided antibiotics - vaginal itching or anaphylaxis (e.g.,
Beta-lactam doses at 6-, 8-, or discharge tightness in the
Antibiotic 12-hourly - Cephalexin is throat and chest,
intervals avoided in wheezing, cough
porphyria. dyspnea) or skin
reactions (rash,
Timing: pruritus,
Daily urticaria). Notify
physician or
nursing staff
immediately if
these reactions
occur.

- Check signs of
eosinophilia,
neutropenia,
thrombocytopeni
a or hemolytic
anemia. Report
these signs to the
physician.

Nursing
Interventions
- Instuct patient
to wash hands
thoroughly and
disinfect
equipment to
help prevent the
spread of
infection. Use
universal
precautions or
isolation
procedures as
indicated for
specific patients.

- Instruct patient
to notify
physician
immediately of
signs of
 superinfection,
including black,
furry overgrowth
on tongue,
vaginal itching or
discharge, and
loose or foul-
smelling stools.

- Instruct patient
and
family/caregivers
to report other
troublesome side
effects such as
severe or
prolonged skin
problems
or GI problems.

Name of Drug Dosage, Route, Mechanism of Indication Adverse Special Nursing

 Frequency and Action Reactions Precautions Considerations
Timing
Generic: Dosage: Oxytocin In the Hypertonicity may Caution should Independent
oxytocin 10 units/mL in 1 production is antepartum occur with tearing be used in - Monitor
amp controlled by a period, oxytocin of uterus patients with frequency,
positive feedback is used to initiate - increased coronary disease duration,
Brand: Postpartum mechanism. This or improve bleeding and strength of
Pitocin, Hemorrhage: mechanism uterine - abruption of hypertension for contractions.
Syntocinon 10 unit IM; add allows the release contractions for placenta it may lead to
10-40 units. of the oxytocin vaginal delivery - fetal bradycardia arterial - Assess vital
hormone when a in situations - low apgar score at contraction signs for baseline
Labor Induction: trigger occurs. where there is 5 min which could data.
0.5-1 mUnit/min The hormone fetal or maternal elevate blood
IV titrate 1-2 then causes an concern. It may Prolonged IV pressure and - Monitor signs
mUnit/min action in the body, be used as well to infusion of compromise the for uterine
such as the induce labor in oxytocin with blood flow. rupture include
Incomplete or letdown of milk or cases of Rh excessive fluid Special FHR
Inevitable the start of labor sensitization, volume can lead to precaution must decelerations,
Abortion: contractions, maternal severe intoxication, be established as sudden increased
10-20 which signals diabetes, seizures, coma and well in patients pain, loss of
mUnit/min; not more production preeclampsia at death. who have or had uterine
exceed 30 units/ of oxytocin. or near term, and previous contractions,
12 hr when delivery is cesarean births hemorrhage and
indicated due to due to the effect hypovolemic
Route: prematurely of uterine shock.
ruptured contraction that
membranes. could - Observe strict I
- Intramuscular Moreover, compromise &O. Be alert to
after delivery of oxytocin is used scars. potential
the placenta in managing Patients with intoxication.
incomplete or hepatic and
- Intravenous inevitable renal - Monitor amount
abortion. And in impairment of blood loss.
Frequency: the postpartum must be taken
q 15-60 until period, oxytocin into - Stop infusion to
contraction is necessary to consideration prevent fetal
pattern reached induce for it anoxia.
to normal contractions in administration
 the 3rd stage of of oxytocin may - Check fundus
labor and to alter the frequently during
control excretion of first few
postpartum drug. postpartum
Timing: bleeding or hours.
hemorrhage.
Classification Contraindications Side Effects: Dependent
Functional: - Significant - nausea and
Uterotonic agents cephalopelvic Vomiting - Notify physician
disproportion for any changes
- Unfavorable Serious side in vital signs and
Chemical: fetal positions or effects: FHR and any
Ergot Alkaloid presentations, - severe allergic vaginal bleeding.
(e.g., transverse reactions Also, if
lies, which are - bleeding after contractions are
undeliverable childbirth prolonged at less
without - abnormal than 2- min
conversion heartbeat intervals.
before delivery) - high blood
- Obstetric pressure - Administer O2
emergencies that (hypertension) therapy if
favor surgery - rupture of the necessary.
- Fetal distress uterus.
where delivery is Patient and
not imminent Family Education
- inadequate - Be aware of
uterine activity purpose and
progress side-effects of
- Hyperactive or oxytocin.
hypertonic - Report
uterus immediately to
- Vaginal delivery healthcare
(e.g., invasive providers for any
cervical sudden severe
carcinoma, active headache.
herpes genitals,
total placenta
previa or
 prolapse of cord)
- Hypersensitivity
- Fetal distress
-polyhydramnios,
- previous major
surgery of
cervix or uterus
(including C-
section)
- over-distension
of the uterus, -

Name of Drug Dosage, Mechanism Indication Adverse Reactions Special Nursing Considerations
Route, of Action Precautions
Frequency
and Timing
Generic: Dosage:500mg Anti- - relief of CNS: headache, It is very - Assess patients
mefenamic inflammatory; moderate pain dizziness, insomnia important who develop
acid capsules analgesic, and when therapy that your severe diarrhea
antipyretic will not exceed Dermatologic: rash, doctor check and vomiting for
Route: Oral activities 1 week pruritus, sweating your dehydration and
related to - -treatment of progress at electrolyte
inhibition of primary Gl: nausea, pain, regular visits. imbalance.
Brand: prostaglandin dysmenorrhea diarrhea, to make sure
Mefenamic Frequency: synthesis; constipation this medicine - Lab tests: With
Acid Every 8 hours exact - Mefenamic acid is working long-term
mechanisms is given to GU: dysuria, renal properly. therapy (not
of action are patient for impairment Blood and recommended)
not known. relief of acute to urine tests obtain periodic
moderately Hematologic: may be complete blood
 Timing: severe pain bleeding, platelet needed to counts, Hct and
TID inhibition with check for Hgb, and kidney
higher doses, unwanted function tests.
neutropenia effects.
Respiratory: - Discontinue drug
dyspnea, This promptly if
hemoptysis, medicine diarrhea, dark
pharyngitis may raise stools,
your risk of hematemesis,
Other: peripheral having a ecchymoses,
edema, heart attack epistaxis, or ash
anaphylactoid or stroke. occur and do not
reactions to This is more use again. Contact
anaphylactic shock likely in physician.
Classification Contraindications Side Effects: people who
Functional: - Contraindicated - Stomach already have
CNS; analgesic, with pain, heart
antipyretic hypersensitivit indigestion, disease or in
y to mefenamic nausea, people who
acid, aspirin vomiting. use this
allergy, and as medicine for
Chemical: treatment of - diarrhea, a long time.
anthranilic perioperative constipation Check with
acid pain with , gas. your doctor
derivatives coronary artery right away if
you are
class of bypass grafting - headache,
having chest
nonsteroidal dizziness.
pain or
anti- - Use cautiously
discomfort,
inflammatory with asthma, - itching, skin
nausea or
drugs renal or hepatic rash
vomiting,
impairment,
pain or
peptic ulcer - ringing in
discomfort in
disease, GI your ears. the arms,
bleeding, jaw, back, or
hypertension, neck, trouble
heart failure, breathing,
pregnancy, slurred
lactation
 speech, or
weakness.

Name of Drug Dosage, Mechanism of Indication Adverse Special Nursing Considerations

Route, Action Reactions Precautions
Frequency
and Timing
Generic: Iron + Dosage: Hemarate Fa Prevention and Allergic Before using - Check the physician’s
Folic + Acid 1 tab tablet works by treatment of iron Sensitization Hemarate Fa order.
+ vitamin B helping red deficiency anemia has been Tablet, inform
complex blood cells to reported your doctor - Follow the 14rights of
Route: deliver oxygen following both about your medication
Oral to all over the oral and current list of
body; parenteral medications, - Advise patient to take
administering administration over the medicine as
Brand: Frequency: required of Hemarate counter prescribed.
Hemarate FA Every morning vitamins for FA products,
the body allergies, - Caution patient to
preexisting make position
Classification Contraindications Side Effects: diseases, and changes slowly to
Functional: Timing: Hypersensitivity, CNS: current health minimize orthostatic
Vitamins and OD Hemochromatosis Dermatologic conditions hypotension,
Minerals , peptic ulcer, Respiratory:
regional enteritis, Nausea, - Instruct patient to
ulcerative colitis vomiting, avoid concurrent use
Chemical: bloating, upper of OTC medicine
Antianemics abdominal without consulting
discomfort and the physician
Diarrhea
- Advise patient to
consult physician if
irregular heartbeat,
dyspnea, swelling of
hands sand feet and
hypotension occurs.

- Inform patient that

angina attacks may
occur 30min.after
administration due to
reflex tachycardia
- Encourage patient to
comply with
additional
intervention for
hypertension like
proper diet, regular
exercise, lifestyle
changes and stress
management

Name of Drug Dosage, Mechanism of Indication Adverse Reactions Special Nursing Considerations
Route, Action Precautions
Frequency
and Timing
Generic: Dosage: Special For maintenance Adverse Reactions: Do not take 2 The use of vitamins as
Multivitamins, Adult 5-10 nutritional of proper tablets of general pick-me-ups is of
minerals. mL supplement nutrition during Pruritus, eruption, Molvite-OB a unproven value and, in
Children 2 formulated to pregnancy and flare, erythema, day as the NHS, they should
mg Fe/kg provide lactation, also xeroderma, nausea, supplement. only be prescribed to
body wt maximum prevention of vomiting, diarrhea, prevent or to treat
nutrients and maternal and constipation, Discuss with a deficiency.
Brand: rapidly fetal complication epigastric distress, doctor if
Molvite-OB develop baby cause by anorexia, abdominal Molvite-OB is Women who are
in the womb. nutritional distention, having too little receiving antiepileptic
Route: Oral It is also deficiencies to photosensitivity, effect in 1 therapy need individual
requisite for promote proper convulsion, fever, month. counselling before
the lactating fetal coma, asystole, CNS starting
mother, the development. dysfunction, Should be used
Frequency: benefits hyperkalemia, with caution in Women who have not
Every consequently pulmonary edema and patients with been taking molvite
morning passed on to urticaria. gastrointestinal supplements and who
Classification the breast-fed Contraindications Side Effects: disorders, since suspect they are
Functional: infant. Hypersensitivity - Gastrointestinal iron salts can pregnant should start at
to Molvite Ob intolerance exacerbate once
Timing: Tablet is a gastrointestinal
OD contraindication. - Allergic bleeding.
Chemical: manifestations
Patients with
hypercalcemia, - Idiosyncratic
hyperkalemia, reactions
sarcoidosis,
nephrolithiasis, - Unusual,
severe renal unpleasant
failure, Wilson's taste in mouth
disease,
hemochromatosi - Upset stomach
s and those - Headache
taking oral
tetracyclines,
antacids,
phosphates and
levodopa.

Combination
therapy with
aldosterone
antagonist and
triamterene may
cause
hypercalcemia.
References:
https://www.coursehero.com/file/9102748/Mefenamic-Aciddocx/
https://www.mims.com/philippines/drug/info/hemarate?type=full
https://www.unilab.com.ph/hemarate-fa/faqs
https://www.tabletwise.net/philippines/molvite-ob-tablet
https://thefilipinodoctor.com/drug/molvite-ob