Professional Documents
Culture Documents
HBS Block 9-1
HBS Block 9-1
d. Domperldone
e. Metoclopramlde
(Hofmann degradatlon) a n d
a. Atracurlum
b. Pancuronlum
C. Rocuronlum
d. Succinylcholine
e. Tubocurarine
or
neuromuscular Junctlon and used for treatment
23. Inhlbits release of Acetylchollne at the
around eyes and mouth.
blepharospasm and for rellef of wrinkles
a. Baclofenne
b. Botulinum toxin
C. Diazepam
d. Dantrolene
e. Tizanidine
for Leishmaniasls:
24. Usually recommended as first line drug
a. Clindamycin
b. Sodium stibogluconate
C. Permethrine
d. Metronidazole
e. Tretinoin
25. One of the following drugs is commonly used both orally and topically for Cutaneous Mycotic
Infectlons:
a. Clotrimazole
b. Ketoconazole
C. Terbinafine
d. Naftifine
e. Tolnaftate
26. Which one of the following drug is conyerted into an active metabolite (A sulfoxide) to kill worms in the
body?
a. Thiabendazole
b. Albendazole
C. Mebendazole
d. lvermectin
e. Pyrantel pamoate
27. The drug of first choice for most Schistosomes and other flukes is:
a. Albendazole
b. Bithionol
C. Metrifonate
d. Oxamniquin -
e. Prazequantal
28. Drug used for treatment of insomnia and non-24-hour sleep-wake disorder, eg. in totally blind adults.
a. Diazepam
Buspiron
Ramelteon
d. Lorazepam
e. Secobarbitone
29. A middle age lady suffering from migraine headache was not responding well to usual first-line
medication and was prescribed an alternate remedy. After a few days she developed ischemie palns
5 of 16 page
b. Semecarpus Anacardium
c.Ricinus communls
d. Croton seeds
e. Ergot
are Included lin
which type of following
trace evidence
37. Skin, tooth pulp, nals, and dandrutf
a. Testimonial evldence
b. Physical evldence
C. Blologlcal evldence
d. Non-blologlcal evldence
e. Chemical evidence
41. Tingling and numbness of the hands and feet and tenderness of the muscles, sometimes with paresis
most commonly affecting the extensors of feet are features of chronic arsenic poisoning. This condition
closely resembles with;
a. Lead encephalopathy
b: Alcoholic neuritis
c. Erythrism
d. Plumbism
e. Saturnism - --- --- -
42. A dead body was found with the presence of complete ligature mark and abrasions on the neck,
bruising of larynx and trachea internaly and fractures of laryngeal cartilage and hyoid bone. What will
be the cause of death in this case:
a. Hanging
b. Smothering
C. Strangulation
d. Choking
e. Autoerotic asphyxia
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43. A
gag8ng material was
eplthellum on the gaggingrecovered
materlal
from a person who was
accused of gagging. Detectlon of
a.
Age of victlm will help to establsh; buCcal
b. Age of accused
C. Sex of victim
d. Sex of accused
e.
Helght of the victim
44. Which one of the
following methods of ldentification Is the surest,
a. DNA profile silmple, and most rellable methoa:
b. Dactylography
C.Gustafson'smethod
d. Anthropometry
e. Poroscopy
c.Opioidpoisoning
d. Organophosphorus poisoning
e. Dhatura poisoning
49. A 70-year-old male is brought by his son to the psychiatric clinic. According to his son, his father has a
habit of forgetting moreover, he tels the doctor that he is under constant observation but tells stories
8 of 16 page
ike
meeting with different people
partlcular perlod. The old man Is recently and about the events which he has not experienceu that
b. Granulomas
C. Eosinophls
d. Vllous atrophy
e. Plasma cells
63. Llver
hlstopathology report of
47 years old man showad features of
a
of the
followlng morphologle feature will favour a dlagnosls of HBV Infectlon?viral hepatitls.
Whicn
a. Ground
glass hepatocytes
b. Lymphold follles
Steatosis
d. Neutrophilic Infiltrate
e. Plasma cells
64. A 38 years old woman
presented with morning stiffness and palnful, swollen
Jolnts. Her serum calclum, phosphorus, alkallne Interphalyngeal
and elbow
phosphatase and urlc acld levels were normal. But RAA
factor, C reactive protein and ESR were ralsed. What is the
in this case? pathogenetlc mechanlsm of Joint destructlon
a.
Deposition of crystals
b. Neutrophil infiltration
C. Pannus formation
d. Wear and tear
e. Porous bones
65. A 34 years old woman
presented with an exophytic cartillage tumor of
showed a cartilage cap with mature bone undemeath. What is upper end of tibia. Biopsy
a. Chondroma your diagnosis?
b. Enchondroma
C. Chondrosarcoma
d. Osteochondroma
e. Osteochramatosis
66. A 12 years old boy presented with bowing of legs and
pigeon chest deformity. He was
rickets. What is the pathogenetic mechanism in
this case? diagnosed with
a. Increase nonmineralized bone matrix
b. Decrease in normal mineralized bone
C. Persistence of fetal osteoid
d. Increased osteoclast activity
e. Decreased osteoblastic activity
67. A 10 years old boy
presented with fever. He had pain and swelling of left leg. X showed
tibial diaphysis. Biopsy showed sheets of small blue ray swelling of
cells with scanty
and vascularity. What is your oytoplasm and extensive necrosis
diagnosis?
Osteosarcoma
Osteoblastoma
Ewing sarcoma
d. Giant cell tumour
Chondrosarcoma
68. A 45 years old man presented with a
pigmented lesion on leg. The lesion had Irregular borders, color
variatlons, variable diameter and ulceration. The doctor suspected
malignant melanoma. What is the
most important prognostic factor in this case?
a. Epidermal involvement
b. Ulceration
Lateral spread
Mitosis
11 of 16 page
e.
9. A37 Depth of Invaslon
Years old man was
may also have.... dlagnosed with cellac disease.
Which of the following
a. Pemphlgus vulgarls bullous sin dsease he
b. Bullous pemphigold
C. Dermatitls herpetlformis
d. Epldermolysis bullosa
e. Darler disease
70. A 35 years old
woman presented with blateral,
hypekeratosis, acanthosls, absent granular layer,symmetrlcal scaly, white plaques. Biopsy showea
Is your diagnosis?
clubbing of rete rldges, and Monroe abscesses. Wna
a. Psorlasls
b. Lichen planus
C. Urticaria
d.
Squamous cell carcinoma
e. Basal cell carcinoma
71. A45 years old
man presented with a
dermls with surface non-heallng ulcer on nose. Blopsy showed nests of tumor cells In
connection, peripheral pallsading, and clefting. What ls your dlagnosis?
a.
Squamous cell carcinoma
b. Malignant melanoma
C. Basal cell carcinoma
d. Dysplastic nevus
e. Spitz nevus
72. What is the
compositlon of staghorn (struvite) renal calculus?
a. Calcium carbonate
b. Magnesium ammonium phosphate
C. Calcium oxalate
d. Uric acid
e. Cysteine
73 A 12 years old
boy presented with generalized edema, puffiness around
Renal biopsy and immunofloresnce was eyes and heavy proteinuria.
essentially normal but electron microscopy showed loss of
podocyte foot processes. What is your diagnosis?
a. minimal change disease
b. focal segmental glomerulonephritis
C. membranous glomerulopathy
d. acute post streptococcal
e. lgA nephropathy
glomerulonephritis
74. A 37 years old blood pressure of 200/120 mmHg. He was
man had a
diagnosed as a case of biopsy In
hypertension. What is the most likely morphologlc lesions in the small renal vessels on renalmalignant
this case?
a. Fibroelastic hyperplasia
b. Medial thickening
c.Hyalinearteriolosclerosis
d. Thrombatic microangiopathy
e. Fibrinoid necrosis
75. Which of the following
morphologlc features is dlagnostic for renal cell carcinoma?
a. Large glands and necrosis
b. Sheets of polygonal cells with deep eosinophilic cytoplasm
C. Clear cells and arborizing thin vessels
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d. Candlda alblcans
e. Coccldloldomycosls
83. Which of the
a.
following vlruses ls the most
HSV-1 common cause of
b. HSV-2 encephallts
VSV
CMV
e. Polio virus
84. Scalded skin
syndrome Is caused
a. by
Streptococcus pyogens exotoxin lexfollatlns) produced by whlch of the following bactena
b. Pseudomonas aeruginosa
C. Staphylococcus aureus
d. Propionibacterlum acne
e. Demodex folliculorum
85. Burn patlents often develop
a. nosocomial Infectlon caused by:
Streptococcus epidermis
b. Corynebacterium spp.
C. Staphylococcus aureus
d. Candida albicans
e.
Pseudomonas aeruginosa
86. The bacteria that
multiply in blocked skin pores, metabolize sebum, and can lead to the
acne are: development of
a. Pseudomonas aeruginosa
b. Propionibacterium spp.
C. Serratia marcescens
d. Streptococcus pyogenes
Acne is not caused
e.
by bacterial infection
87. A 60 years old farmer
working barefooted in the fields develop abdominal discomfort and
progressive anaemia ,had a past history of itching and papule formation on his left slowly
foot His stool
routine examinatlon revealed oval
transparent ova with a granulated mass in the centre. Which
parasite can be responsible for this infection;
a. a Ancylostoma duodenale
b. Ascaris lumbricoides
C. Enterobius vermicularis
d. Trichuris trichiura
e. Hymenolepis nana
88. Which of the following may be the only detectable serological marker durlng the earty convalescent
phase of HBV infection (window phase)7
a. Hepatitis B core antigen (HBCAg)
b. Hepatitis Be antigen (HBeAg)
C. Hepatitis Bsurface antigen (HBSAg)
d. Hepatitis B e antibody ( HBeAb)
e. Hepatitis Bcore antibody (HBc Ab)
89. A patient in an ICU is on CVP line. His blood culture show growth of gram positive coccl which are
catalase positive and coagulase negative. The most lIkely etiologlc agent Is..
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a. Staphylococcus aureus
b. Staphylococcus epldermidls
C.Enterococcus faecalls
d. Streptococcus Pyogenes
e. Streptococcus agalactea
90. Infants between 6-12 months are
more
or older persons because: susceptlble to systamlc
menlngococcal disease than newborns,
a. Thls age group
speclfic receptors for
b. Infants of thls age group are menlngococcal pll on nasopharynx
deflclent In C5, C6, and C7
CMaternally-derlved
d. Exposure
bacterlocidal antlbodles have In the
declined in complement system
Incldence is hlghest In thls this age group
Infants of thls group develop age group
Immune
woman, has blurred vision and complex agalnst this disease
91. A forty year old
nelghbourhood for her expertlse In home cannedslurred speech. She ls afebrlle. She ls well known in her
illness Is? vegetables and frults. The most
likely cause
of her
a.
Clostridlum perfringens toxin acting on
b. Clostridium botulinum toxin acting on the synaptic terminal of
neuromuscular junctlon
C.
Clostridlum botulinum toxin acting on synaptic terminal of
d. Clostridlum the cranlal nerves neuromuscular Junction
difficile acting on the
e.
Clostridium botulinum toxin acetylcholine receptors
92. The gastric acting on the
adrenerglc receptors
biopsy of a patlent with a
negative rods within the mucous history of peptic ulcer
disease
layer of the stomach. Urea breath revealed gull wing shaped gram-
gram-negative rod whlch Is a test was also
a. predisposing factor for gastric carcinoma
Bacteroldes fragilis positlve. This enterlc
Is;
b. Campylobacter jejuni
C. Helicobacter pylori
d. Salmonella typhi
e. Vibrio parahemolyticus
93. Which of the following set
of
bacterlal meningitis 48 hours findings
will most likely favour
after the
a
diagnosis of tuberculous meningitis over
a. Lymphocytosi development of neck rigldity?
, normal/ slightly elevated
b.
Lymphocytosis, markedly elevated glucoseglucose
concentration
C.
d.
Lymphocytosis and low glucose level
e.
Polymorphonuclear leukocytosis, normal/elevated glucose
94.
Polymorphonuclear leukocytosis, low glucose
A 23-year-old woman
comes to your office
urination, increased frequency of because, for 3 days, she has
urination, anda continual feeling thatexperienced burning with
'dipstick' urine tests are consistent with she needs urinate.
produces a lactose-fermenting Gram-negativeuncomplicated cystitis. Culture of urine ontostandard Rapid
rod. In situations such as media
pathogen? this, what Is the most likely
a. Enterobacterfaecium
b. Escherichia coli
C. Klebsiella pneumonia
d. Proteus vulgaris
e. Pseudomonas aeruginosa
95. A 22-year woman
develops dilarrhea. She reports pain on passage of stool, which is
smear of stool black
and tarry. A
revealed, cysts and amoeboid forms containing
ingested erythrocytes. Endoscopy
reveals ulceratlons 15 of 16
bloody diarrhea.
of his
colonlc mucosa.. page
Which organism Is
a. Entamoeba hlstolytica most likely to have caused the
b.
Glardla lamblla patlents
C.
d.
Salmonella enterica
e.
Shigella dysenterlae
96. Vibrlo cholera
Infectlon wlth
a. dermatophyte Is most often assoclated
intravenous drug with
b.
inhalatlon of the abuse
adherence of the organism from contaminated bird feces
97.
d. organism to
Fecal-oral transmisslon
perspiration molst skin
A girl who prlcked her
to an ulcer. Several finger while pruning some
rose bushes
nodules then
develop develops a local pustule that
Aspergillus fumigatus along the local lymphatic progresse
dralnage. The most likely ager"
. Sporothrix schenckil
C. Cryptococcus neoformans
d. Candida albicans
98. A
35-year-old man with severe
analgesic and antispasmodic radiating pain in the right
hypochondrium was hydrated and given i/v
drugs. After several hours he passes
the stone reveals a kidney stone.
a struvite (magnesium Laboratory analysis
of
following organisms can ammonium phosphate) stone. Infection with which of the
promote the production of such stones?
a.
Escherichia coli
b. Proteus mirabilis
C. Pseudomonas aeruginosa
d. Staphylococcus saprophyticus
e. Ureaplasma urealyticum
99. Rabies is identified by which of the following inclusion bodies
a. Guarneri bodies
b. Negri bodies
C. Cowdry A bodies
d. Cowdry B bodies
e. Downie bodies
100. All of the following statements are true regarding poliovirus except
a. It is transmitted
by feco-oral route
b. Asymptomatic infections are common in children
C. There is a single serotype causing infection
d Live attenuated vaccine produces herd immunity
e. It is a positive sense RNA virus