METFORMIN-GLIBENCLAMIDE (Metformin hydrochloride + Glibenclamide, Metformin hydrochloride + Glyburide)

you have to follow closely to help control your blood

Why is this medicine prescribed to you?
Metformin-glibenclamide is prescribed to treat type 2
diabetes.
How do you use it?
Use metformin-glibenclamide exactly as instructed by your
doctor for it to be effective.
• Take metformin-glibenclamide before meals.
• If you are given the extended-release tablet, swallow it
whole; do not split, crush or chew.
• If you forget to use this medicine on schedule, use it
immediately as you remember. However, if it is already
time for the next dose, just proceed with your next
regular dose schedule.
• Unless advised by your doctor, do not double or adjust
dosage, or stop use even if you feel well.
What do you need to know before you use it?
• Inform your doctor or pharmacist:
- if you are pregnant, trying for a baby or
breast-feeding;
- if you have any of the following conditions: allergy,
type 1 diabetes, diabetic ketoacidosis, kidney
problem, liver problem, heart problem, heart failure,
recent heart attack or stroke, glucose-6-phosphate
dehydrogenase (G6PD) deficiency, blood disorder
(porphyria), severe infection, dehydration;
- if you are using any other prescription or over-the-
counter (OTC) medicines and dietary or
herbal supplements.
• Keep a regular check-up schedule. You need to test for
blood sugar levels regularly and keep a record of your
blood sugar levels. Your doctor will show you how to
test; explain how to use the test results; advise you on
the tests needed to check and monitor your progress
while under treatment with this medicine. Your doctor
will also advise you on the proper diet, exercise, weight
control and care of eyes, foot, gums and teeth which
sugar levels.
• Too low blood sugar levels can cause hypoglycemia. The
symptoms of hypoglycemia include nausea, headache,
fast heartbeat, irritability, chills, unusual sweating,
shaking, feeling hungry, vision changes, nervousness,
confusion, weakness, dizziness, drowsiness and fainting.
At the first sign of hypoglycemia, drink or eat something
containing sugar like glucose tablet, sugar, honey,
candy, orange juice or non-diet soda. If there is no
improvement in your condition, seek immediate
medical help.
• Avoid alcohol to help manage your condition.
• If you need to undergo surgery or dental procedure,
inform your doctor or dentist that you are using this
medicine before going through it.
• Side effects may possibly occur as with most medicines.
You may not experience any side effect; however, if you
experience any of these side effects with metformin-
glibenclamide, inform your doctor immediately,
especially if they become severe or persistent: nausea,
vomiting, diarrhea, upper stomach pain, loss of
appetite, taste changes, headache, dizziness, rash,
itching, visual problems, pale or yellowed skin, clay-
colored stools, yellowing of the skin or eyes, sneezing,
runny nose, cough and allergic reactions such as hives,
difficulty breathing and swelling of the face, lips, tongue
or throat.
• If you experience dizziness or vision problems, do not
drive, operate machinery or perform any activity which
will need you to be alert or to see clearly.
• The side effects mentioned here are not complete and
others may occur. If you observe other side effects or
reactions, call your doctor for advice.
• Do not share your medicine with others even if you
have the same disease symptoms.
How do you handle it before and after use?
Store in a cool, dry place, protected from light and
moisture. Keep the medicine out of children’s reach.
Discard it properly when it is expired or no longer needed.

This pharmacy information service of Mercury Drug Corporation contains only basic drug
information and must not be relied upon as substitute for professional medical care. It is intended
to be used as supplementary information to consultation with your doctor. Mercury Drug
www.mercurydrug.com Corporation shall not be responsible or liable for any claims or damages arising from the use or
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