Assignment 3: Pharmacology

Please find the information on the following drugs that are commonly used during emergencies.
Submission date: 31/10/2021 by 6pm.

Medication Indication Side effect Nursing responsibilities Dilution (If

required)

Brilinta 90mg Treatment of thrombosis Dizziness, nausea, 1. Assess patient for

diarrhea, slow symptoms of stroke,
heartbeat rate, rash, peripheral vascular
and allergic disease, or MI
reactions. periodically during
therapy.
2. Inform patient that they
will bleed and bruise
more easily and it will
take longer to stop
bleeding.

Nitroderm patch Prevention as well as Blurred vision 1. Check blood pressure

10mg treatment of angina Decreased blood and pulse before each
pressure administration of NTG–
Dizziness blood pressure can drop
Headache precipitously after a
Increased heart rate single dose.
Lightheadedness 2. Advised patient to rest in
Paresthesia (tingling bed and avoid ambulation
or pricking to prevent fall.
sensation) 3. Change the patch
according to the time.
Aspirin 300mg Anti-inflammatory Hypersensitivity, 1. Assess pain one hour
analgesic which can nausea and before or after medication
relieve pain and swelling vomiting 2. Monitor for bleeding
ringing in ears tendency.
pain or discomfort in
stomach or lower
chest after eating.

Angised/GTN Treat and prevent heart- Blurred vision 1. Check blood pressure
0.5mg related chest pain Decreased blood and pulse before each
(angina) pressure administration of NTG–
Dizziness blood pressure can drop
Headache precipitously after a
Increased heart rate single dose.
Lightheadedness 2. Advised patient to rest in
Paresthesia (tingling bed and avoid ambulation
or pricking to prevent fall.
sensation)

Amiodarone Treat certain types of Nausea, vomiting, 1. Monitor blood pressure Dextrose 5%
150mg/3mls serious (possibly fatal) constipation, loss of and apical pulse prior to 22ml
irregular heartbeat (such appetite, shaking, or administration.
as persistent ventricular tiredness may 2. Encourage patient to
fibrillation/tachycardia) occur. wear sunglasses for
photosensitivity.
3. Encourage patient to rest
in bed to prevent fall if
feel dizzy after taking
medication.

Succinyl Anaesthesia to facilitate Jaw rigidity. 1. Ensure patient is fully Normal Saline
(Suxamethonium tracheal intubation and Low blood pressure ventilated on a controlled
100mg/2mls) mechanical ventilation (hypotension) rate of breathing before
 surgical procedures. Muscle relaxation administration.
resulting in 2. Ensure ECG, oxygen
respiratory saturation, End Tidal CO2
depression to the and arterial pressure
point of breathing alarms are on with
cessation (apnea) appropriate alarm
Respiratory settings.
depression.

Naloxone Used in complete or Nausea, vomiting, 1. Monitor respirations and Normal Saline
0.4mg/ml partial reversal of opioid sweating or other vital signs. 10ml
depression tachycardia. 2. Monitor surgical and
obstetric patients closely
for bleeding.

Dopamine Treatment of low blood Palpitations, 1. Correct hypovolemia with Normal Saline
200mg/5ml pressure due to heart tachycardia fluid resuscitation before 500ml
attack, infection, heart (increased heart initiating dopamine
surgery, or trauma and rate), and infusion.
heart failure. headache. 2. Monitor blood pressure,
pulse, and peripheral
pulses every 15 minutes.
3. Monitor hourly urine
output.
4. Cardiac monitor should
be used on patients
receiving dopamine
infusion.

Lasix 20mgl/2ml Treatment of edema Increased urination, 1. Observe patients

associated with CHF, thirst, receiving parenteral drug
cirrhosis of liver, and muscle cramps, carefully; closely monitor
kidney disease, itching or rash, BP and vital signs.
 including nephrotic weakness, Sudden death from
syndrome. dizziness, cardiac arrest has been
spinning sensation, reported.
diarrhea 2. Monitor for S&S of
hypokalemia
3. Monitor BP during
periods of diuresis and
through period of dosage
adjustment.

Solu Cortef Treat various conditions Stomach upset, 1. Monitor for persistent 1ml of WFI
100mg such as arthritis, severe headache, backache or chest pain,
(Hydrocortisones) allergies, blood dizziness, trouble compression and
diseases, breathing sleeping, appetite spontaneous fractures of
problems, certain changes, menstrual long bones and vertebrae
cancers, eye diseases, period changes, present hazards.
intestinal disorders, and acne, or 2. Be alert to possibility of
skin diseases. pain/redness/swellin masked infection and
g at the injection site delayed healing (anti-
inflammatory and
immunosuppressive
actions).
References:

1mg.com. (2021a). Angised 0.5mg Tablet: View Uses, Side Effects, Price and Substitutes. 1mg. https://www.1mg.com/drugs/angised-

0.5mg-tablet-12269

1mg.com. (2021b). Dopamine 200mg Injection: View Uses, Side Effects, Price and Substitutes. 1mg.

https://www.1mg.com/drugs/dopamine-200mg-injection-354776

1mg.com. (2021). Nitroderm TTS 10mg Transdermal Patch: View Uses, Side Effects, Price and Substitutes. 1mg.

https://www.1mg.com/drugs/nitroderm-tts-10mg-transdermal-patch-237752

Aspirin 300 - Patient Information Leaflet (PIL) - (emc). (2021). EMC. https://www.medicines.org.uk/emc/product/8627/pil#gref

Amiodarone Oral: Uses, Side Effects, Interactions, Pictures, Warnings & Dosing - WebMD. (2021). WebMD.

https://www.webmd.com/drugs/2/drug-4521/amiodarone-oral/details

Amiodarone: Indication, Dosage, Side Effect, Precaution | MIMS Malaysia. (2021). MIMS Malaysia.

https://www.mims.com/malaysia/drug/info/amiodarone?mtype=generic

Brilinta Dosage & Drug Information | MIMS Malaysia. (2021). MIMS Malaysia. Retrieved October 27, 2021, from

https://www.mims.com/malaysia/drug/info/brilinta

Furosemide. (2021). RobHolland. http://www.robholland.com/Nursing/Drug_Guide/data/monographframes/F048.html

Naloxone Hydrochloride Injection USP 400 micrograms/1ml (0.4mg/ml, 1ml) - Summary of Product Characteristics (SmPC) - (emc).

(2021). EMC. https://www.medicines.org.uk/emc/product/6589/smpc#gref

Suxamethonium Chloride 50mg/ml Solution for Injection - Summary of Product Characteristics (SmPC) - (emc). (2021). EMC.

https://www.medicines.org.uk/emc/product/5189/smpc#gref