Assessment Details

Subject NMDF211 Nutritional Biochemistry

Type Assessment II- Integrative Biochemical analysis

Due Date Sunday (11:59pm) following Week 12 Word Limit 1000+/- 10%
Weight 35% Total Marks 100

LEARNING OUTCOMES ASSESSED: 2 and 4

Task:
Investigate the major metabolic pathways of the given case and present detailed discussion on the role of
nutrient cofactors, substrates, hormones and enzymes in succeeding/failing to maintain normal metabolic
functions within the body. Explain integration among biochemical pathways and their correlation with client’s
symptoms.

OVERVIEW:
The assignment should be structured as a report. The purpose of writing a report is to present information
which can be described or analysed. Your report can have headings and subheadings, can include tables,
graphs and diagrams; and information can be presented in dot point form where appropriate.

Case study
A client named Susan has sought your nutritional advise for alleviation from her symptoms. Susan is a 44-
year-old female who has gained 10 Kg over last two years. She enjoys wearing perfumes daily and
watches her favourite web series till late night. Her GP has diagnosed her with fatty liver (Non-alcoholic
fatty liver disease-NAFLD). Her biochemical report (see Table below) indicates elevated liver enzymes,
inflammation, insulin resistance and issues with hepatic clearance of metabolites (cholesterol, cortisol,
hepatic toxins, microbial by-products etc)
Susan experiences bloating and abdominal pain after she eats. She suffers from fatigue and is a stressed
person. She has a history of anxiety.
She doesn’t have time to plan meals or cook and often buys take away foods.
When stressed, she drinks beer. She does not like fruits/salads and has a food intolerance to shellfish.
As her nutritionist, you would like to investigate her liver dysfunction and gut-liver connection. You would then
prioritise to alleviate her symptoms through dietary and lifestyle interventions with the aim to support liver-gut
axis healing.

Family history:
Father: Liver cancer, Mother: Diabetes Type II,
Sister: Diabetes Type II, Brother: Hypertension
One day diet recall
She likes to eat egg and meat (particularly beef).
Breakfast: Oats with soymilk (one medium bowl), orange juice (packaged-one glass)
Mid-morning: Black tea (I mug) with cream biscuits (4)
Lunch: Beef curry (one large bowl) with rice (175g)
Evening tea/Dinner: Pepperoni Pizza (one large/frozen)
Water-1 L approx. a day
Medications: Susan is not currently on any medication but has a history of extensive antibiotic use; at age 1
to 4 years for tonsillitis, and aged 13-15 years for mild acne.

Physical and Biochemical Tests:

Test Result Reference Range

Blood pressure 145/92 mm of Hg Systolic: 110-120 mm/Hg

Diastolic: 70 – 80 mm/Hg
Heart rate 76 beats per minute 72-84 beats per minute
Waist Hip Ratio 1.4 <0.8
Temperature 37˚C 35.8 – 37.3˚C
Body mass index (BMI) 28 kg/m2 Normal 18.5-24.9 kg/m2
Blood glucose fasting 7.0 mmol/L Below 5.5mmol/L
Fasting insulin 16mU/L Fasting 2 - 12 mU/L
2hr post prandial 5 - 30 mU/L
Liver tests:
Albumin 37 g/L 34–48
Protein 72 g/L 65–85
Total bilirubin 13 µmol/L 2–24
GGT 68 U/L <60
ALP 112 U/L 30–110
ALT 57 U/L <55
AST 50U/L <45
Total Cholesterol 5.7mmol/L Below 4.0mmol/L
ALP: Serum alkaline phosphatase test measures the level of alkaline phosphatase (an enzyme) in the blood to assess liver functioning and to
find liver lesions.
ALT: Alanine transaminase test measures the level of alanine aminotransferase: an enzyme found mostly in the liver that is released into the
bloodstream after acute liver cell damage.
AST: Aspartate transaminase test measures the level of aspartate transaminase: an enzyme that is released into the bloodstream after acute liver
cell damage.
GGT: Gamma-glutamyl transpeptidase test measures the level of gamma-glutamyl transpeptidase: an enzyme that indicates liver function, and to
detect alcohol ingestion.

Questions:

1. (a) Investigate functioning of liver phase I in Susan’s case. Present your clinical and nutritional
biochemical findings about reasons for suboptimal liver functioning while commenting on the
constituents, enzymes and, cofactors involved in the liver phase I. Your discussion will integrate the
significance/functioning of liver phase I, Kupffer cells and glutathione in relation to client’s signs,
symptoms, diet, family history and findings in the biochemical report.
(b) Discuss Gut-liver axis and its significance in NAFLD as relevant for the given case to demonstrate
your understanding of nutritional biochemical rationale underlying client’s gut/liver condition. Highlight
relevant pathways to rationalise her biochemical report, signs, symptoms while deducing facts from
investigation of her diet and family history through nutritional biochemistry perspectives. Overall while
 answering Question 1 (a) and (b), you should explain at least four (4) relevant signs/symptoms (e.g.,
bloating, anxiety) and three (3) pertinent biochemical findings (e.g., liver enzymes, BMI and insulin).

2. Suggest one (1) dietary inclusion as an intervention (food or food based, can be a supplement or a
nutrient but NOT an herb) using scientific evidence (based on human research) that may benefit this
client with a rationale. Comment on dose, form of inclusion and its impact on the biochemical findings
in the given case.

3. Suggest one (1) lifestyle inclusion as an intervention using scientific evidence (based on human
research) that may benefit this client with a rationale. Comment on duration, type/form of inclusion
and its impact on the biochemical findings in the given case.

No conclusion is required

The following is a basic report structure which can be used to successfully complete this assessment task.

Headings Include following relevant points (as a guide only)

General Introduction Briefly give an overview of the case including significance of the client’s main symptoms, medical condition and
to the report biochemical report. Based on this overview present the aims of your report.
(approx. 10-15% of
word count)
Body/discussion Q1 (a) and (b)
n Discuss:
(55-65% of the (a) Liver detox phase I
word count) (b) Role of glutathione and Kupffer cells
(c) Integration of gut dysbiosis and liver detoxification
Access full articles below to start your research:
1.Modulation of Metabolic Detoxification Pathways Using Foods
Hodges, R. E., & Minich, D. M. (2015). Modulation of Metabolic Detoxification Pathways Using Foods and Food-Derived
Components: A Scientific Review with Clinical Application. Journal of nutrition and metabolism, 2015, 760689.
https://doi.org/10.1155/2015/760689
2. Liver Microbiome Axis in Health and disease
Adolph, T. E., Grander, C., Moschen, A. R., & Tilg, H. (2018). Liver-Microbiome Axis in Health and Disease. Trends in
immunology, 39(9), 712–723. https://doi.org/10.1016/j.it.2018.05.002
3. Nutritional aspects of detoxification
Cline, J. (2015). Nutritional aspects of detoxification in clinical practice. Alternative therapies in health and medicine, 21 3,
54-62.
4.Fatty liver and microbiome
Campo, L., Eiseler, S., Apfel, T., & Pyrsopoulos, N. (2019). Fatty Liver Disease and Gut Microbiota: A Comprehensive
Update. Journal of clinical and translational hepatology, 7(1), 56–60. https://doi.org/10.14218/JCTH.2018.00008
5.NAFLD and insulin resistance
Kitade, H., Chen, G., Ni, Y., & Ota, T. (2017). Nonalcoholic Fatty Liver Disease and Insulin Resistance: New Insights and
2 Potential New Treatments. Nutrients, 9(4), 387. https://doi.org/10.3390/nu9040387
Dietary/nutritional
advice (10-15% of Suggest one nutrient or food that you would include in Susan’s diet to ensure optimal functioning of liver. Explain the
word rationale for your choice (biochemical pathways that are supported by inclusion of this food).
count) Suggested readings:
Kieffer, D. A., Martin, R.J., Adams, S.J. (2016). Impact of Dietary Fibres on Nutrient Management and Detoxification
Organs: Gut, Liver, and Kidneys. Advances in Nutrition, 7(6), 1111–1121. https://doi.org/10.3945/an.116.013219. Access
Here
Paolella, G., Mandato, C., Pierri, L., Poeta, M., Stasi, M.D., and Vajro, P. (2014). Gut-liver axis and probiotics: Their role
in non-alcoholic fatty liver disease. World J Gastroenterol. 20(42):
15518–15531. doi: 10.3748/wjg.v20.i42.15518. Access Here
(you may use these references for your report)
3.Lifestyle
Advice (10-15% of Suggest an appropriate lifestyle recommendation that may assist in alleviating client’s symptoms.
word count) Explain the rationale for your choice.
A suggested reading: Smart, N.A., King, N., McFarlane, J.R., Graham, PL., Dieberg, G. (2018). Effect of exercise training
on liver function in adults who are overweight or exhibit fatty liver disease: a systematic review and meta-analysis
British Journal of Sports Medicine, 52:834-843. Access Here
References followed Appendices need to be labelled and referenced, and each appendix should be on a separate page. Any table in the
by Appendix (if any) appendix should have dot points and only 10% of the total word count of the assessment. Excess
words/paragraphs/tables will not be assessed.
It should also adhere to the following format requirements:

• Title page (Subject code and name; Student name and number; Lecturer name; Type of assignment
(i.e. Report); Due date; and Word count)
• Your filename should contain the subject code, assignment name, your name and version.
Example filenames: NMDF211-report-JaneDoe-draft.pdf OR NMDF211-report-JaneDoe-final.pdf
• Word count to be clearly displayed on the cover sheet or title page
• The report should be typed using standard conservative fonts such as Times New Roman or Arial of
at least 12 point and double spaced.
• Fully referenced as per the American Psychological Association (APA) Referencing Guidelines,
available here:
https://acnm.s3-ap-southeast-2.amazonaws.com/pub/DOCID-2102554854-15539.pdf

Report due date is Sunday (11:59 pm) following Week 12.

Academic Writing and Student Integrity

Writing on all assessments is expected to be of an academic standard and presentation, and all non-original
work must be properly referenced.

For assistance in ensuring this academic standard, please refer to the Communication Skills Handbook, 4th
edition (2014) by Summers & Smith and the APA Referencing Guidelines.

For assistance with referencing, Mendeley citation software, and plagiarism please refer to links on the Library
homepage http://library.endeavour.edu.au.

The Library Research Skills Tutorial (located on the LMS drop down Library tab) covers these areas plus
other relevant skills through videos and quizzes.

Additional support can be found at the top of the LMS Main Page. The Study Skills tab contains a section on
Academic Writing.

Note that all forms of plagiarism and cheating are taken very seriously at Endeavour. Please ensure that you
are familiar with the Academic Integrity Policy - Higher Education and that you are mindful of avoiding the
use of any work that is not your own without proper attribution, as well as never allowing your work to be used
by another student.

Word Count
Word count must be clearly displayed on the title page or cover sheet. Words in excess of 10% beyond the
required word count will not be marked. Required word count includes in-text citations but excludes text
appearing in tables, graphs, figures, footnotes, captions and end-text references.
Tables, graphs, and figures can enhance assignment presentation if used in moderation to convey directly
relevant information. However, generally tables, graphs and figures should be included as Appendices at the
end of your assignment with an interpretation of these in text. Tables, graphs and figures should not be used
as tools to increase the amount of information that you are conveying whilst remaining within the required
word count, nor are they a substitute for your own synthesis or interpretation of the material. Thus, as a guide,
tables, graphs or figures presented should not consist of more than 10% of the total assignment word count,
whilst keeping in mind that any words so included are not part of the required word count.
 INTRODUCTION
Exemplary Proficient Developed Acquiring Underdeveloped Not developed

(5 marks) (4 marks) (3 marks) (2 marks) (1 mark) (0)

Introduction Extremely well-defined aims Few well-defined aims Few aims (n=1/2/3) are Few aims that are not well- Few irrelevant aims are The aim for the report is not
(10) (at least three) are presented (n=2/3) are presented for the presented for the report that defined are presented for the presented for the report that stated or presented in a non-
for the report that concisely report that concisely identify are not well-defined and report that do not exactly do not identify purpose and logical manner without
Aim identify purpose with purpose but omits enough somewhat identify purpose identify purpose and loosely do not align with the context. context.
appropriately detailed detailed context. but omits enough detailed align with the context.
context. context
(5 marks) (4 marks) (3 marks) (2 marks) (1 mark) (0)
Comprehensive and A concise overview of the An overview of the case is An incomplete overview of Overview of the case is Overview of the case is not
Case overview &
exhaustive overview of the case is presented along with presented in short along with the case is presented without presented as a single presented, or some non-
understanding
case is presented along with the relevance of the some relevance of the relevance of the symptoms sentence in the report or has logical relevance of the
the relevance of the symptoms and the findings in symptoms and few findings in and the findings in the major omissions in including symptoms and findings in the
symptoms and the findings in the biochemical report with the biochemical report with biochemical report with major the relevance of the biochemical report is
the biochemical report that minor omissions that minor omissions that omissions that demonstrates symptoms and the findings in presented that does not
demonstrates complete demonstrates some demonstrates limited limited understanding of the the biochemical report demonstrate any
understanding of the gut-liver understanding of the gut-liver understanding of the gut-liver gut-liver axis with NAFLD. thereby not demonstrating understanding of the gut-liver
axis with NAFLD. axis with NAFLD. axis with NAFLD. any understanding of the gut- axis with NAFLD.
liver axis with NAFLD.
BODY AND DISCUSSION
Exemplary Proficient Developed Acquiring Underdeveloped Not developed
(5 marks) (4 marks) (3 marks) (2 marks) (1 mark) (0 mark)
Q1 (a) and (b)
Thorough clear, concise and Clear, concise and insightful Clear and concise discussion Some discussion that is Insufficient and incomplete No discussion presented to
Demonstration insightful discussion that discussion that demonstrates demonstrates understanding incomplete and does not discussion that does not demonstrate understanding
of demonstrates a superlative a good level of understanding of some of the constituents, demonstrates adequate demonstrate even basic of functions, importance and
understanding level of understanding of all of most of the constituents, enzymes, cofactors involved understanding of functions, understanding of functions, relevance of Liver detox
of status and the constituents, enzymes & enzymes, cofactors involved in Liver detox phase I and importance and relevance of importance and relevance of pathway I in the given case.
reasons for the cofactors involved in Liver in Liver detox phase I and its functions, importance and Liver detox pathway I in the Liver detox pathway I in the
suboptimal Liver detox phase I along with its its functions, importance and relevance leading to given case with major given case and is presented
detox I pathway functions, importance and relevance leading to nutritional biochemical omissions of the pertinent in a non-logical manner.
and liver-gut relevance leading to nutritional biochemical imbalances in the given case factors.
integration nutritional biochemical imbalances in the given case with omissions of the most
through imbalances in the given case. but with few omissions. pertinent factors.
investigation (5 marks) (4 marks) (3 marks) (2 marks) (1 mark) (0 mark)
and Thorough clear, concise and Clear, concise and insightful Clear discussion that Discussion has major Insufficient and non-logical No discussion presented to
interpretation of insightful discussion, discussion that demonstrates demonstrates understanding omissions in demonstrating discussion that demonstrates demonstrate any academic
client’s demonstrates a superlative a good level of understanding of few functions and understanding of functions, basic understanding of understanding of the
symptoms, level of understanding of all of functions, importance and importance of Kupffer cells importance and relevance of functions and importance of functions, importance and
biochemical the functions, importance and relevance of Kupffer cells in but omits relevance to the Kupffer cells in the given Kupffer cells, fails to include relevance of Kupffer cells in
report, family relevance of Kupffer cells in the given case with minor given case and discussion on case. relevance of Kupffer cells in the given case.
history, dietary the given case. omissions of pertinent the pertinent factors. the given case
and lifestyle factors.
habits and (5 marks) (4 marks) (3 marks) (2 marks) (1 mark) (0 mark)

© Endeavour College of Natural Health Assessment - Integrative Biochemical Analysis

Last updated on 3-Mar-21 5.0 Page 6 of 10
 family history Thorough, concise and an
(40). insightful discussion that
demonstrates a superlative
level of understanding of
constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process. The
suboptimal functioning of
glutathione is sighted and
clinically correlated with the
relevant
symptoms/signs/findings in
the biochemical report as
evident in the given case.
(5 marks)
Exemplary investigative
skills are demonstrated in
discussion through
explanation of pertinent
symptoms of suboptimal liver
pathways
(n≥4)
(5 marks)
Superlative interpretative
skills are demonstrated in
discussion that expertly
explains rationale for the
pertinent biochemical
findings in the context of liver
detoxification process (n≥3).
(5 marks)
Relevance of liver pathways
is discussed expertly and in
detail in relation to all the
factors in the client’s diet,
lifestyle and family history.
(5 marks)
Thorough clear, concise, in
depth discussion that
demonstrates a high level of
understanding of
components of gut-liver
axis including factors and
metabolites involved.
(5 marks)
© Endeavour College of Natural Health
Last updated on 3-Mar-21
A concise and insightful
discussion that demonstrates
a good understanding of
constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process. But,
the suboptimal functioning of
glutathione is slightly
overlooked and not expertly
correlated with the relevant
symptoms/signs/findings in
the biochemical report as
evident in the given case
(4 marks)
Good investigative skills
are demonstrated in
discussion through
explanation of few important
symptoms of suboptimal liver
pathways
(n=3/4)
(4 marks)
Good interpretative skills
are demonstrated in
discussion that expertly
explains rationale for the
pertinent biochemical findings
(n=3/4) in the context of liver
detoxification process with
omission of a major
symptom/finding.
(4 marks)
Relevance of liver pathways
is discussed in detail in
relation to key factors in the
client’s diet, lifestyle and
family history.
(4 marks)
Demonstrates a good level of
understanding of
components of gut-liver
axis with minor omissions of
imperative factors and
metabolites
(4 marks)
5.0
Clear and concise discussion
that demonstrates some
understanding of
constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process with
minor omissions. The
suboptimal functioning of
glutathione is completely
overlooked, and report lacks
short to cohesively correlate
it with the relevant
symptoms/signs/findings in
the biochemical report as
evident in the given case
(3 marks)
Some investigative skills
are demonstrated in
discussion through
explanation of few irrelevant
symptoms of suboptimal liver
pathways
(n=3)
(3 marks)
Fair display of interpretative
skills in the discussion that
does not explain appropriate
rationale for the given
biochemical findings (n=3) in
the context of liver
detoxification process and
omission of a major
symptom/finding is evident.
(3 marks)
Relevance of liver pathways
is discussed moderately in
relation to few factors in the
client’s diet, lifestyle and
family history.
(3 marks)
Demonstrates a basic level of
understanding of gut-liver
axis with major omissions of
components, and imperative
factors/ metabolites
(3 marks)
A short, unclear discussion
presented that does not
demonstrate logical
understanding of
constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process. The
suboptimal functioning of
glutathione is completely
overlooked, and report fails to
correlate it with the relevant
symptoms/signs/findings in
the biochemical report as
evident in the given case
(2 marks)
Investigative skills are not
clearly demonstrated in
discussion through
explanation of irrelevant
symptoms of suboptimal liver
pathways in a non-coherent
manner (n<2))
(2 marks)
Display of basic
interpretative skills in the
discussion that does not
explain rationale for the
biochemical findings (n=2/3)
in the context of liver
detoxification process and
omission of a major
symptom/finding is evident.
(2 marks)
Relevance of liver pathways
is discussed fairly in relation
to the client’s diet, lifestyle
and family history with
some omissions.
(2 marks)
Demonstrates a low level of
understanding of gut-liver
axis with major omissions of
components, and imperative
factors/ metabolites
(2 marks)
Insufficient discussion that
demonstrates basic
understanding of
constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process as
major omissions are noted.
The discussion omits
correlation of suboptimal
functioning of glutathione with
the relevant
symptoms/signs/findings in
the biochemical report as
evident in the given case
(1 mark)
Investigative skills are not
demonstrated in a non-logical
discussion through
explanation of just one
symptom of suboptimal liver
pathways
(n=1)
(1 mark)
Interpretative skills are not
demonstrated in the
discussion that explains
rationale for a biochemical
finding (n=1) but not in the
context of liver detoxification
process
(1 mark)
Relevance of liver pathways
is not discussed in relation to
any of the client’s diet,
lifestyle and family history
or is incoherent.
(1 mark)
Demonstrates no
understanding of gut-liver
axis with major omissions of
components, and imperative
factors/ metabolites.
(1 mark)
Assessment - Integrative Biochemical Analysis
Page 7 of 10
No discussion presented to
demonstrate understanding
of constituents, cofactors,
functions and significance of
glutathione in liver
detoxification process. The
functioning of glutathione is
not correlated with any
symptoms/signs/findings in
the biochemical report as
evident in the given case.
(0 mark)
Investigative skills are not
demonstrated in the
discussion and report lacks
explanation of any relevant
symptoms of suboptimal liver
pathways (n<1))
(0 mark)
Interpretative skills in the
discussion are incongruent.
(0 mark)
Relevance of liver pathways
is not discussed in relation to
any of the client’s diet,
lifestyle and family history
(0 mark)
Discussion on the gut-liver
axis is completely omitted or
presented in an unsound
manner that is not relevant.
(0 mark)
 Exemplary and insightful
discussion that demonstrates
a high level of understanding
of the integration of gut-
liver axis while explaining
dysregulated pathways
underlying client’s
condition/symptoms/biochemi
cal findings
Exemplary
Q2 and 3 (5 marks)
Dietary and
The selection of the
lifestyle
food/supplement reflects
inclusions:
superlative understanding of
using scientific
the liver/gut dysregulation
evidence (based
and discussion includes all
on human
the correct mechanism of
research) that
actions of that food as
may benefit this
pertinent to the client’s
client with a
symptoms and biochemical
rationale.
findings
Comment on
duration,
type/form of (5 marks)
inclusion and its The dose, form, and
impact on duration of inclusion of
biochemical food/supplement is well
findings in the justified in the discussion
given case in a superlative manner with
Exclusion of a the support of appropriate
food or lifestyle evidence by referring to
will not be clinical research among
marked (20). humans
(5 marks)
The selection of the lifestyle
inclusion reflects superlative
understanding of the liver/gut
dysregulation and discussion
includes all the correct
mechanism of actions of that
intervention as pertinent to
the client’s symptoms and
biochemical findings
© Endeavour College of Natural Health
Last updated on 3-Mar-21
A good discussion that
demonstrates adequate
understanding of the
integration of gut-liver axis
while explaining dysregulated
pathways but few omissions
with respect to
factors/metabolites
imperative to rationalise
underlying client’s
condition/symptoms/biochem
ical findings.
Proficient
(4 marks)
The selection of
food/supplement reflects
adequate understanding of
the liver/gut dysregulation
and discussion includes a
few mechanisms of action
of that food that seem correct
and are related to the client’s
symptoms and biochemical
findings
(4 marks)
The dose, form, and
duration of inclusion of
food/supplement is justified
in the discussion with the
support of pertinent evidence
by referring to clinical
research among humans
with minor omissions.
(4 marks)
The selection of the lifestyle
inclusion reflects adequate
understanding of the liver/gut
dysregulation and discussion
includes a few mechanisms
of action of that intervention
that seem correct and are
related to the client’s
symptoms and biochemical
findings
5.0
A fair discussion that
demonstrates some
understanding of the
integration of gut-liver axis of the integration of gut-
in an illogical manner.
Omissions with respect to
dysregulated pathways,
factors/metabolites
imperative to rationalise
underlying client’s
condition/symptoms/biochemi cal findings are noted.
cal findings are noted.
INTERVENTIONS/INCLUSIONS
Developed
(3 marks)
The selection of
food/supplement reflects
inadequate understanding of
the liver/gut dysregulation
and discussion includes just
one correct mechanism of
action of that food that is
roughly related to the client’s
symptoms and biochemical
findings
(3 marks)
The dose, form, and
duration of inclusion of
food/supplement is justified
in the discussion with the
support of pertinent evidence
by referring to research-
based articles that have not
tested that food/supplement
among humans
(3 marks)
The selection of the lifestyle
inclusion reflects inadequate
understanding of the liver/gut
dysregulation and discussion
includes just one correct
mechanisms of action of that
intervention that is roughly
related to the client’s
symptoms and biochemical
findings
Few illogical sentences are
presented that do not
demonstrate understanding
liver axis. Major omissions
with respect to dysregulated
pathways, factors/metabolites
imperative to rationalise
underlying client’s
condition/symptoms/biochemi
Acquiring
(2 marks)
The selection of
food/supplement reflects
inadequate and insufficient
understanding of the liver/gut
dysregulation and discussion
does not include any
mechanism of action of that
food and is not related to the
client’s symptoms and
biochemical findings
(2 marks)
The dose or form or
duration of inclusion of
food/supplement is not
justified
in the discussion and lacks
support of pertinent evidence
of research-based articles
(2 marks)
The selection of the lifestyle
inclusion reflects inadequate
and insufficient
understanding of the liver/gut
dysregulation and discussion
does not include any
mechanisms of action and is
not related to the client’s
symptoms and biochemical
findings
Does not demonstrate
understanding of the
integration of gut-liver axis
Major omissions with respect
to dysregulated pathways,
factors/metabolites
imperative to rationalise
underlying client’s
condition/symptoms/biochemi
cal findings are noted.
Underdeveloped
(1 mark)
The selection of
food/supplement reflects
inadequate and insufficient
understanding of the liver/gut
dysregulation. No discussion
is evident or illogical facts are
presented to indicate some
mechanisms of action of
that food which are unrelated
to client’s symptoms and
biochemical findings
(1 mark)
The dose or form or
duration of inclusion of
food/supplement is not
presented in the discussion
or lacks support of pertinent
evidence of research-based
articles
(1 mark)
The selection of the lifestyle
inclusion reflects inadequate
and insufficient
understanding of the liver/gut
dysregulation. No discussion
is evident or illogical facts are
presented to indicate some
mechanisms of action which
are unrelated to client’s
symptoms and biochemical
findings
Assessment - Integrative Biochemical Analysis
Page 8 of 10
No discussion is presented,
or unscientific discussion is
noted that does not
demonstrate understanding
and relevance of the
integration of gut-liver axis
as per client’s
condition/symptoms/biochemi
cal findings.
Not developed
(0 mark)
No food/supplement is
presented as an intervention.
No discussion is evident or
illogical facts are presented
to indicate some
mechanisms of action
(0 mark)
The dose or form or
duration of inclusion of
food/supplement is not
presented in the discussion
or some baseless anecdotal
mentions are included
(0 mark)
No lifestyle inclusion is
presented as an intervention.
 (5 marks)
The dose, form, and
duration of inclusion of
lifestyle change is well
justified in the discussion
in a superlative manner with
the support of appropriate
evidence by referring to
clinical research among
humans.
(4 marks)
The dose, form, and
duration of inclusion of
lifestyle change is justified
in the discussion with the
support of pertinent evidence
by referring to clinical
research among humans
with minor omissions.
(3 marks)
The dose, form, and
duration of inclusion of
lifestyle change is justified
in the discussion with the
support of pertinent evidence
by referring to research-
based articles that have not
tested that activity among
humans
(2 marks)
The dose or form or
duration of inclusion of
lifestyle change is not
justified
in the discussion and lacks
support of pertinent evidence
of research-based articles
(1 mark)
The dose or form or
duration of inclusion of
lifestyle change is not
presented in the discussion
or lacks support of pertinent
evidence of research-based
articles
(0 mark)
The dose or form or
duration of inclusion of
lifestyle change is not
presented in the discussion
or some baseless anecdotal
mentions are included

STRUCTURE, WRITTEN EXPRESSION AND WORD COUNT

(5 marks)
Structure Exemplary display of
organisation, academic writing as evident
style, format and by well-organized and
written cohesive writing of concepts
expression and and expert inclusion of
word count (20) content page, subheadings,
tables, figures and
appendices.
(5 marks)
Excellent format and use of
English language
(5 marks)
Demonstrates a high level of
originality, critical thinking,
evaluation and insight into
the topic
Exemplary
(4 marks)
Good display of academic
writing as evident by an
organized and cohesive
writing of concepts with minor
mistakes while interpreting
from research facts. Content
page, subheadings, tables,
figures and appendices are
included.
(4 marks)
Good format and use of
English language
(4 marks)
Demonstrate a good level of
originality, critical thinking,
evaluation and insight into the
topic
Proficient
(3 marks)
Fair display of academic
writing as evident by an
organized writing of concepts
but with major mistakes in
cohesive/summative
inscription while drawing from
research-based facts.
Content page, subheadings,
tables, figures and
appendices are partially
included.
(3 marks)
Clear format and use of
English language
(3 marks)
Demonstrate a fair level of
originality, critical thinking,
evaluation and insight into
the topic
Developed
(2 marks)
Some academic writing as
evident by incoherent writing
of concepts. Major mistakes
in cohesive/summative
inscription are noted while
drawing from research-based
facts. Content page,
subheadings, tables, figures
and appendices are partially
included.
(2 marks)
Several grammatical, spelling
and/or punctuation errors
displaying minor problems
with
English construction
(2 marks)
Demonstrate low level of
originality, critical thinking,
evaluation and insight into
the topic
Acquiring Underdeveloped Not
(1 mark) (0 mark)
Academic writing is not The discussion is not
robust as evident by academically presented.
incoherent writing of Personal comments are
concepts and incorrect included. Report fails to draw
interpretation of research- form the research facts.
based facts. Major mistakes
in cohesive/summative
inscription are noted and
personal
comments/unacademic
language is included. No
inclusion of content page,
subheadings, tables, figures
and appendices.
(1 mark) (0 mark)
Numerous errors of Major problems with
grammatical, spelling and/or English construction is noted
punctuation displaying major
problems with
English construction
(1 mark) (0 mark)
Poor display of Does not demonstrate
originality, critical thinking, originality, critical thinking,
evaluation and insight into evaluation and insight into
the topic the topic

(5 marks) (0 mark)
Absolute adherence to the Word count excessive by more than 10% and the extra content will not be marked.
word count (1000-1100
words)

SOURCE OF INFORMATION AND REFERENCES

© Endeavour College of Natural Health Assessment - Integrative Biochemical Analysis

Last updated on 3-Mar-21 5.0 Page 9 of 10
 Exemplary
(5 marks)
Evidence of extensive
Source of reading on the topic as
information and evidenced by a large variety
references (10) of primary references, mainly
peer-reviewed articles, and
government scientific reports
(>15).
(5 marks)
Demonstrate correct and
accurate application of APA
referencing style with no
mistakes in punctuations, in-
text-and the reference list
Proficient
(4 marks)
Evidence of moderate
amount of reading on the
topic as evidenced by a
considerable variety of
references, including peer
reviewed articles,
government scientific reports,
textbooks, and government
websites (10-15).
(4 marks)
Demonstrate good
application of APA
referencing style with few
mistakes in the punctuation
and in in-text referencing
(n=2)
Developed
(3 marks)
Evidence of fair amount of
reading on the topic as
evidenced by a variety of
references, including peer
reviewed journal articles,
government reports,
textbooks, etc (5-9). Some
online/internet/web-based
sites are included
(3 marks)
Demonstrate fair application
of APA referencing style with
few mistakes in the
punctuation, reference list
and in in-text referencing
(n=3/4)
Acquiring
(2 marks)
Evidence of little reading on
the topic as evidenced by a
few references that are
predominantly secondary
sources mainly website blogs
or sites ending with org., au,
edu, etc. A few research-
based articles are included.
(<5)
(2 marks)
Demonstrate some
inaccurate application of APA
referencing style with
numerous mistakes in the
punctuation, reference list
and in in-text referencing
(n=4/5)
Underdeveloped
(1 mark)
Evidence of limited reading
on the topic as evidenced by
null or <5 references that are
inappropriate sources. Some
online/internet/web-based
sites are included or a few
scientific articles are noted.
(1 mark)
Demonstrate incorrect
application of APA
referencing style with various
mistakes in the punctuation,
reference list and in in-text
referencing (n>5)
Not developed
(0 mark)
Evidence of restricted
reading on the topic as
evidenced by null or <5
references that are either
inappropriate sources or
personal anecdotes without
critique
(0 mark)
Demonstrate incorrect
application of APA
referencing style

© Endeavour College of Natural Health Assessment - Integrative Biochemical Analysis

Last updated on 3-Mar-21 5.0 Page 10 of 10