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Name: AIRA SHANE MARGES

Year/Section: BSN 2D
Laboratory Activity #1
Clinical Comparison
Intestinal Nematodes
Parasite Possible cause of infection Clinical Manifestations Host/s Treatment
1. Capillaria Ingestion of uncooked freshwater Abdominal pain, borborygmus, Freshwater/ brackish Electrolyte replacement, Antidiarrheal
philippinensis or brackish water fish with larva diarrhea, few weeks (weight loss, fish and humans and Abendazole (200mg, 2x/day for 10
anorexia, vomiting, edema – leads to days)
severe protein -losing enteropathy,
malabsorption of fats and sugars, low
electrolyte levels, especially
postassium because of diarrhea. If left
untreated, usually leads to death
2. Schistosoma Skin comes in contact with Fever, cough, abdominal pain, Freshwater gastropod Praziquantel and anti-inflammatory
japonicum contaminated freshwater in which diarrhea, hepatosplenomegaly, and snails, Oncomelania effect of garlic can be shown to help
certain types of snails that carry eosinophilia. hupensis reduce Schistosoma infection in
schistosomes are living. humans, it may offer a valid route
forward.
3. Ascaris After accidentally ingesting the Severe abdominal pain, fatigue, Humans and swine Albendazole and mebendazole, are the
Lumbricoides eggs of the A. lumbricoides vomiting, weight loss or malnutrition drugs of choice for treatment of Ascaris
roundworm. and a worm in your vomit or stool. infections, regardless of the species of
worm. Infections are generally treated
for 1–3 days.
4. Taenia By the tapeworm species Taenia Abdominal pain, nausea, diarrhoea or Meat of cattle Single oral dose of praziquantel 5 or 10
saginata saginata (beef tapeworm), Taenia constipation may arise when the mg/kg. Alternatively, a single 2-g dose
solium (pork tapeworm), and tapeworms become fully developed in of niclosamide (not available in the US)
Taenia asiatica (Asian tapeworm). the intestine, approximately 8 weeks is given as 4 tablets (500 mg each) that
after ingestion of meat containing are chewed one at a time and
cysticerci. swallowed with a small amount of
water.
5. Trichuris Consuming dirt or water Abdominal pain, diarrhea, and, in Humans Mebendazole or albendazole. The
trichura contaminated with feces containing heavy infections, anemia and suggested dose of mebendazole is 100
whipworm parasites or their eggs. undernutrition. mg twice a day for 3 days or
albendazole is 200 to 400 mg twice a
day for 3 days. Mebendazole has been
shown to be more effective and is
considered first-line treatment.
Name: AIRA SHANE MARGES
Year/Section: BSN 2D
Laboratory Activity #1

6. Strongyloids Parasitic roundworm S. Diarrhea, pain, tenderness, nausea, Human parasite. Single dose of the antiparasitic
stercoralis stercoralis. This worm infects vomiting and peripheral eosinophilia However, patent medication ivermectin (Stromectol).
mainly humans. Most humans get infections with This drug works by killing the worms in
the infection by coming into contact parasitic females your small intestine. Your doctor may
with contaminated soil. have been detected in also prescribe two courses of
other primates albendazole (Albenza), to be taken 10
(chimpanzees,
days apart.
monkeys, etc.
7. Fasciolopsis By eating aquatic plants or Intestinal obstruction, abdominal pain, Pigs and dogs. Praziquantel 25 mg/kg orally 3 times a
buski ingesting contaminated water. nausea, vomiting, and fever. day for 1 day. Prevention involves not
drinking contaminated water or eating
freshwater plants in areas where
Fasciolopsis buski is endemic.
8. Fasciola Eating raw watercress or other Abdominal pain and hepatomegaly. cattle, sheep, and Triclabendazole, a benzimidazole
hepatica water plants contaminated with buffaloes compound active against immature and
immature parasite larvae. adult fasciola parasites, is the drug of
choice for treatment of fascioliasis.
9. Heterophyes By trematode parasites occurring Diarrhea and colicky abdominal pain. Heterophyes requires Praziquantel 25 mg/kg orally 3 times a
heterophyes in areas where brackish water fish Migration of the eggs to the heart, a snail as an day for 1 day for H. heterophyes and M.
is consumed raw or under resulting in potentially fatal intermediate host. yokogawai and 20 mg/kg orally 3 times
improperly cooked conditions. myocardial and valvular damage, has Cerithideopsilla a day for 1 day for N. salmincola.
been reported from the Philippines. cingulata is the main
first intermediate host
for H.
10. Echinostoma The snail Pila conica, which is In heavy infections, gastrointestinal Many animals Praziquantel is the drug of choice for
ilocanum eaten uncooked in parts of the signs/symptoms may occur. In which including birds, echinostomiasis.
Philippines. Other sources of heavy worm burdens caused anemia, carnivores, rodents,
infections are clams, tadpoles, malnutrition, or intestinal perforation, and humans may
frogs, and fish, all serving as serve as definitive
second intermediate hosts for hosts for various
echinostomid species.
echinostomes.
Name: AIRA SHANE MARGES
Year/Section: BSN 2D
Laboratory Activity #1
11. Wucheriria Most of the infections worldwide Limb lymphedema, inguinal Humans serve as the Diethylcarbamazine (DEC) is the drug
bancrofti are caused by Wuchereria lymphadenopathy and hydrocele. definitive host and of choice in the United States. The drug
bancrofti. In Asia, the disease can mosquitos as the kills the microfilariae and some of the
also be caused by Brugia malayi intermediate host. adult worms.
and Brugia timori. The infection The adult parasites
spreads from person to person by reside in the
mosquito bites. lymphatics of the
human host.

PARASITIC PROTOZOA
Possible cause of
Parasite Clinical Manifestations Host/s Treatment
infection
1. Entamoeba Ingestion of mature Loose feces (poop), Humans and Metronidazole 750 mg PO tid
histolytica cysts (2) in fecally stomach pain, and occasionally in for 7-10 days (35-50 mg/kg/d
contaminated food, stomach cramping. dogs, cats, cattle in children) OR tinidazole 2 g
water, or hands. and pigs. once PO daily for 5 days (50
mg/kg/day in children 3 years
of age or older). Luminal
agents used are
paromomycin, iodoquinol, and
diloxanide furoate.
2. Entamoeba This parasite, which is Diarrhea or dysentery with Trophozoites live in Metronidazole has been
gingivalis transmitted by simple frequent, small and often the oral cavity of reported to be effective.
droplet infection, is bloody stools. Chronic humans, residing in
one potential cause of amoebiasis can present the gingival pockets
severe oral with gastrointestinal near the base of the
inflammation. symptoms plus fatigue, teeth.
weight loss and occasional
fever.

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