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    Antibiotic Cross Sensitivity Chart

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    thao hoang
    This document provides an antibiotic cross-allergy chart for the pharmacy department at VCH-PHC. It uses symbols to indicate potential cross-sensitivities between different antibiotics. Blank spaces mean the antibiotics are not cross-sensitive, while X's mean to avoid due to risk of cross-sensitivity. Symbols with asterisks mean to use caution and monitor vital signs after the first dose due to some risk of cross-reaction due to similar structures. It also notes to avoid all penicillins, cephalosporins and carbapenems if the patient has a history of severe delayed skin reactions to beta-lactam antibiotics.

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    Antibiotic Cross Sensitivity Chart

    Uploaded by

    thao hoang
    543 views1 page
    This document provides an antibiotic cross-allergy chart for the pharmacy department at VCH-PHC. It uses symbols to indicate potential cross-sensitivities between different antibiotics. Blank spaces mean the antibiotics are not cross-sensitive, while X's mean to avoid due to risk of cross-sensitivity. Symbols with asterisks mean to use caution and monitor vital signs after the first dose due to some risk of cross-reaction due to similar structures. It also notes to avoid all penicillins, cephalosporins and carbapenems if the patient has a history of severe delayed skin reactions to beta-lactam antibiotics.

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    This document provides an antibiotic cross-allergy chart for the pharmacy department at VCH-PHC. It uses symbols to indicate potential cross-sensitivities between different antibiotics. Blank spaces mean the antibiotics are not cross-sensitive, while X's mean to avoid due to risk of cross-sensitivity. Symbols with asterisks mean to use caution and monitor vital signs after the first dose due to some risk of cross-reaction due to similar structures. It also notes to avoid all penicillins, cephalosporins and carbapenems if the patient has a history of severe delayed skin reactions to beta-lactam antibiotics.

    Copyright:

    © All Rights Reserved
    Download as PDF, TXT or read online from Scribd
    Flag for inappropriate content
    Download as pdf or txt
    543 views1 page

    Antibiotic Cross Sensitivity Chart

    Uploaded by

    thao hoang
    This document provides an antibiotic cross-allergy chart for the pharmacy department at VCH-PHC. It uses symbols to indicate potential cross-sensitivities between different antibiotics. Blank spaces mean the antibiotics are not cross-sensitive, while X's mean to avoid due to risk of cross-sensitivity. Symbols with asterisks mean to use caution and monitor vital signs after the first dose due to some risk of cross-reaction due to similar structures. It also notes to avoid all penicillins, cephalosporins and carbapenems if the patient has a history of severe delayed skin reactions to beta-lactam antibiotics.

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    VCH-PHC PHARMACY DEPARTMENT

    ANTIBIOTIC CROSS-ALLERGY CHART


    KEY TO SYMBOLS:
    Blank = Not cross-sensitive as different structure
    X = AVOID. Potential for cross-sensitivity due to similar structure
    or based on clinical reports of cross-senstivity
    * = USE WITH CAUTION. Similar side chain - Potential for cross
    reaction. Monitor first dose closely (vital signs at 15, 30, and

    Amikacin
    60 minutes post-first dose)

    Amoxicillin
    NF = Non-formulary drug

    Ampicillin
    Azithromycin
    Cefadroxil (NF)
    Amikacin Note: AVOID all penicillins, cephalosporins and carbapenems if
    Amoxicllin patient reports history of severe delayed skin allergy to ANY
    beta-lactam antibiotic (i.e. Steven-Johnson syndrome (SJS),
    Ampicillin X toxic epidermal necrolysis (TEN), drug rash with eosinophilia and

    Cefazolin
    systemic symptoms (DRESS), acute generalized exanthematous

    Cefepime
    Azithromycin pustolosis (AGEP)).
    Cefadroxil (NF) X X

    Cefixime
    Cefotaxime
    Cefazolin

    Cefprozil (NF)
    Cefepime

    Cefoxitin
    Cefixime *

    Ceftazidime
    Cefotaxime X *

    Ceftriaxone
    Cefoxitin

    Cefuroxime

    Chloramphenicol
    Cefprozil (NF) X X X

    Cephalexin
    Ceftazidime * * *
    * X *

    Ciprofloxacin
    Ceftriaxone X

    Clarithromycin
    X * X X * X

    Cotrimoxazole (Sulfa)
    Cefuroxime

    Clindamycin
    Cephalexin X X X X
    Chloramphenicol

    Cloxacillin
    Ciprofloxacin

    Daptomycin
    Clarithromycin X
    Clindamycin

    Ertapenem
    Erythromycin
    Cloxacillin X X
    Cotrimoxazole (Sulfa)

    Gentamicin
    Daptomycin

    Imipenem
    Levofloxacin
    Ertapenem

    Meropenem

    Piperacillin/Tazobactam
    Erythromycin X X

    Metronidazole
    Gentamicin X

    Moxifloxacin
    Imipenem X
    Levofloxacin X

    Penicillin
    Meropenem X X

    Streptomycin
    Metronidazole
    Moxifloxacin X X

    Tigecycline
    *

    Tobramycin
    Penicillin X X X

    Vancomycin
    Piperacillin/Tazobactam X X * * * X X
    Streptomycin X X
    Tigecycline
    Tobramycin X X X
    Vancomycin
    Ref: Adapted with permssion from Beta-lactam Antibiotic Cross-Allergy Chart, Interior Health Authority
    Updated: May 2021 PHARMACY/ASPIRES

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